GB1239814A - Process for the preparation of 7-aminocephalosporanic acid and its derivatives - Google Patents
Process for the preparation of 7-aminocephalosporanic acid and its derivativesInfo
- Publication number
- GB1239814A GB1239814A GB35757/68A GB3575768A GB1239814A GB 1239814 A GB1239814 A GB 1239814A GB 35757/68 A GB35757/68 A GB 35757/68A GB 3575768 A GB3575768 A GB 3575768A GB 1239814 A GB1239814 A GB 1239814A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- agent
- group
- prepared
- imino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 title abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 239000004215 Carbon black (E152) Substances 0.000 abstract 2
- 229930186147 Cephalosporin Natural products 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 229940124587 cephalosporin Drugs 0.000 abstract 2
- 150000001780 cephalosporins Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229930195733 hydrocarbon Natural products 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 241001137862 IDIR agent Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 201000011243 gastrointestinal stromal tumor Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- ODUCDPQEXGNKDN-UHFFFAOYSA-N nitroxyl Chemical compound O=N ODUCDPQEXGNKDN-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003808 silyl group Chemical group [H][Si]([H])([H])[*] 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1896—Compounds having one or more Si-O-acyl linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0834—Compounds having one or more O-Si linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL676710835A NL150798B (nl) | 1967-08-07 | 1967-08-07 | Werkwijze voor de bereiding van 7-aminocefalosoranzuur en derivaten daarvan. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1239814A true GB1239814A (en) | 1971-07-21 |
Family
ID=19800883
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB35757/68A Expired GB1239814A (en) | 1967-08-07 | 1968-07-26 | Process for the preparation of 7-aminocephalosporanic acid and its derivatives |
Country Status (13)
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4242509A (en) * | 1979-04-13 | 1980-12-30 | Eli Lilly And Company | Process for producing 7-amino-7-alkoxycephalosporins |
| US4286088A (en) * | 1977-12-12 | 1981-08-25 | Takeda Chemical Industries, Ltd. | Process for preparing 7-aminocephalosporins |
| US4562253A (en) * | 1982-08-06 | 1985-12-31 | Biochemie Gesellschaft M.B.H. | Deacylation of amides |
| US6642020B2 (en) | 2001-04-19 | 2003-11-04 | Bioferma Murcia S.A. | Process for preparing cephalosporin derivatives |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE758587A (fr) * | 1969-11-17 | 1971-05-06 | Fujisawa Pharmaceutical Co | Procede de preparation de derives d'acide 7-aminocephalosporanique et nouveaux produits ainsi obtenus |
| JPS4948760B1 (enrdf_load_stackoverflow) * | 1970-12-25 | 1974-12-23 | ||
| GB1388267A (en) * | 1971-06-17 | 1975-03-26 | Glaxo Lab Ltd | Preparation of antibiotic compounds |
-
1967
- 1967-08-07 NL NL676710835A patent/NL150798B/xx not_active IP Right Cessation
-
1968
- 1968-07-18 IL IL30392A patent/IL30392A/en unknown
- 1968-07-26 ES ES356543A patent/ES356543A1/es not_active Expired
- 1968-07-26 GB GB35757/68A patent/GB1239814A/en not_active Expired
- 1968-07-30 CH CH1141768A patent/CH513920A/de not_active IP Right Cessation
- 1968-07-30 IE IE920/68A patent/IE32230B1/xx unknown
- 1968-07-31 BE BE718824D patent/BE718824A/xx not_active IP Right Cessation
- 1968-08-01 YU YU1833/68A patent/YU34589B/xx unknown
- 1968-08-01 DK DK372068AA patent/DK142912B/da not_active IP Right Cessation
- 1968-08-05 SE SE6810565A patent/SE373591B/xx unknown
- 1968-08-05 IT IT38917/68A patent/IT1035011B/it active
- 1968-08-06 AT AT766168A patent/AT280475B/de not_active IP Right Cessation
- 1968-08-06 FR FR1583480D patent/FR1583480A/fr not_active Expired
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4286088A (en) * | 1977-12-12 | 1981-08-25 | Takeda Chemical Industries, Ltd. | Process for preparing 7-aminocephalosporins |
| US4242509A (en) * | 1979-04-13 | 1980-12-30 | Eli Lilly And Company | Process for producing 7-amino-7-alkoxycephalosporins |
| US4562253A (en) * | 1982-08-06 | 1985-12-31 | Biochemie Gesellschaft M.B.H. | Deacylation of amides |
| US6642020B2 (en) | 2001-04-19 | 2003-11-04 | Bioferma Murcia S.A. | Process for preparing cephalosporin derivatives |
| US6730497B2 (en) | 2001-04-19 | 2004-05-04 | Bioferma Murcia S.A. | Process for preparing cephalosporanic acid derivatives using β-ketoacid derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| IE32230B1 (en) | 1973-05-16 |
| DK142912B (da) | 1981-02-23 |
| DE1770980B2 (de) | 1977-04-07 |
| FR1583480A (enrdf_load_stackoverflow) | 1969-10-31 |
| AT280475B (de) | 1970-04-10 |
| NL6710835A (enrdf_load_stackoverflow) | 1969-02-11 |
| DK142912C (enrdf_load_stackoverflow) | 1981-10-05 |
| CH513920A (de) | 1971-10-15 |
| IL30392A (en) | 1971-12-29 |
| YU34589B (en) | 1979-10-31 |
| IL30392A0 (en) | 1968-09-26 |
| DE1770980A1 (de) | 1972-03-02 |
| IT1035011B (it) | 1979-10-20 |
| SE373591B (sv) | 1975-02-10 |
| YU183368A (en) | 1979-04-30 |
| IE32230L (en) | 1969-02-07 |
| BE718824A (enrdf_load_stackoverflow) | 1969-01-31 |
| NL150798B (nl) | 1976-09-15 |
| ES356543A1 (es) | 1970-01-16 |
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