GB1157176A - Hydroxyamino-Acid-containing Peptides and a Process for Preparing them - Google Patents

Hydroxyamino-Acid-containing Peptides and a Process for Preparing them

Info

Publication number
GB1157176A
GB1157176A GB25298/67A GB2529867A GB1157176A GB 1157176 A GB1157176 A GB 1157176A GB 25298/67 A GB25298/67 A GB 25298/67A GB 2529867 A GB2529867 A GB 2529867A GB 1157176 A GB1157176 A GB 1157176A
Authority
GB
United Kingdom
Prior art keywords
hydroxy
group
amino acids
acid
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB25298/67A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG, Farbwerke Hoechst AG filed Critical Hoechst AG
Publication of GB1157176A publication Critical patent/GB1157176A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/065—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for hydroxy functions, not being part of carboxy functions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1,157,176. Hydroxy amino acids and peptides containing them. FARBWERKE HOECHST A.G. 1 June, 1967 [1 June, 1966], No. 25298/67. Heading C2C. Hydroxy-α-amino acids and their derivatives in which the hydroxy group is blocked by a 2,2,2-trihalo-1-acylamino-ethyl group are prepared by reacting the amino acid or its derivative with N-acyl-1-trihalogeno-acetaldimine. Peptides containing hydroxy-amino acids are also prepared by condensing an hydroxyamino acid or a peptide containing such an acid having a free amino group or a free carboxylic group but having its hydroxy group protected by a 2,2,2-trihalogeno-1-acylamino-ethyl group, with an amino acid having a free carboxy or free amino group respectively, and, if desired, removing all or some of the protecting groups in the resulting peptide. Medicaments contain the hydroxy-α-amino acids or hydroxy-α-amino acid derivatives which are the products of the process above. The dicyclohexylamine salts of N- and O- protected hydroxy-α-amino acids and peptides containing them are prepared.
GB25298/67A 1966-06-01 1967-06-01 Hydroxyamino-Acid-containing Peptides and a Process for Preparing them Expired GB1157176A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF0049355 1966-06-01

Publications (1)

Publication Number Publication Date
GB1157176A true GB1157176A (en) 1969-07-02

Family

ID=7102953

Family Applications (1)

Application Number Title Priority Date Filing Date
GB25298/67A Expired GB1157176A (en) 1966-06-01 1967-06-01 Hydroxyamino-Acid-containing Peptides and a Process for Preparing them

Country Status (3)

Country Link
DE (1) DE1543594A1 (en)
GB (1) GB1157176A (en)
NL (1) NL6707485A (en)

Also Published As

Publication number Publication date
NL6707485A (en) 1967-12-04
DE1543594A1 (en) 1969-09-25

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees