GB1141392A - A 4-aminoquinaldine derivative, its preparation and pharmaceutical compositions containing it - Google Patents
A 4-aminoquinaldine derivative, its preparation and pharmaceutical compositions containing itInfo
- Publication number
- GB1141392A GB1141392A GB24714/66A GB2471466A GB1141392A GB 1141392 A GB1141392 A GB 1141392A GB 24714/66 A GB24714/66 A GB 24714/66A GB 2471466 A GB2471466 A GB 2471466A GB 1141392 A GB1141392 A GB 1141392A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aminoquinaldine
- derivative
- pharmaceutical compositions
- preparation
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- COCFIBRMFPWUDW-UHFFFAOYSA-N 2-methylquinolin-4-amine Chemical class C1=CC=CC2=NC(C)=CC(N)=C21 COCFIBRMFPWUDW-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- HQAIROMRVBVWSK-UHFFFAOYSA-N 4-chloro-2-methylquinoline Chemical compound C1=CC=CC2=NC(C)=CC(Cl)=C21 HQAIROMRVBVWSK-UHFFFAOYSA-N 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000003904 antiprotozoal agent Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- YQLZOAVZWJBZSY-UHFFFAOYSA-N decane-1,10-diamine Chemical compound NCCCCCCCCCCN YQLZOAVZWJBZSY-UHFFFAOYSA-N 0.000 abstract 1
- MDKXBBPLEGPIRI-UHFFFAOYSA-N ethoxyethane;methanol Chemical compound OC.CCOCC MDKXBBPLEGPIRI-UHFFFAOYSA-N 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US461531A US3362875A (en) | 1965-06-04 | 1965-06-04 | N4, n4'-decamethylene-bis(4-amino)-quinaldine diacetate compositions for controllingtopical infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1141392A true GB1141392A (en) | 1969-01-29 |
Family
ID=23832934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB24714/66A Expired GB1141392A (en) | 1965-06-04 | 1966-06-02 | A 4-aminoquinaldine derivative, its preparation and pharmaceutical compositions containing it |
Country Status (3)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5756517A (en) * | 1996-10-25 | 1998-05-26 | Bayer Aktiengesellschaft | Use of bisquinoline compounds in the treatment of cerebral disorders |
| US6174897B1 (en) | 1996-10-25 | 2001-01-16 | Bayer Aktiengesellschaft | Bis-(quinolyl)-diamines |
| US5866562A (en) * | 1996-10-25 | 1999-02-02 | Bayer Aktiengesellschaft | Ring-bridged bis-quinolines |
| ES2201674T3 (es) * | 1998-01-26 | 2004-03-16 | Smithkline Beecham Plc | Derivados de quinolina con propiedades antibacterianas. |
| GB9917408D0 (en) * | 1999-07-23 | 1999-09-22 | Smithkline Beecham Plc | Compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3026322A (en) * | 1962-03-20 | Bis-quevaldines | ||
| US2791582A (en) * | 1953-11-12 | 1957-05-07 | Allen & Hanburys Ltd | Polyalkylene bis-1 |
| US3027378A (en) * | 1959-06-26 | 1962-03-27 | Stark Hans Carl | Method of preparing nu4, nu4'-alkylene-n1, n1'-alkylene-bis-4-aminoquinaldinium-dihalides and resultant products |
| US3147182A (en) * | 1961-03-20 | 1964-09-01 | Johnson & Johnson | Antiseptic mixture of decamethylene 1, 10-bis-4-aminoquinaldinium salt and cetyl pridinium salt |
| DE1169948B (de) * | 1961-06-06 | 1964-05-14 | Dr Hans Carl Stark | Verfahren zur Herstellung von antibakteriell wirksamen N, N'-Alkylen-1, 1'-alkylen-bis-(4-aminochinolinium-halogeniden) |
-
1965
- 1965-06-04 US US461531A patent/US3362875A/en not_active Expired - Lifetime
-
1966
- 1966-06-02 GB GB24714/66A patent/GB1141392A/en not_active Expired
- 1966-06-03 FR FR64140A patent/FR5559M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3362875A (en) | 1968-01-09 |
| FR5559M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1967-11-20 |
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