GB1138419A - Ergoline derivatives - Google Patents
Ergoline derivativesInfo
- Publication number
- GB1138419A GB1138419A GB3388767A GB3388767A GB1138419A GB 1138419 A GB1138419 A GB 1138419A GB 3388767 A GB3388767 A GB 3388767A GB 3388767 A GB3388767 A GB 3388767A GB 1138419 A GB1138419 A GB 1138419A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ergoline
- acid
- dimethyl
- ergoline derivatives
- aminomethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- AWFDCTXCTHGORH-HGHGUNKESA-N 6-[4-[(6ar,9r,10ar)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-methylpyridin-2-one Chemical class O=C([C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC(Br)=C(C=34)C2)C1)C)N(CC1)CCN1C1=CC=CC(=O)N1C AWFDCTXCTHGORH-HGHGUNKESA-N 0.000 title abstract 3
- -1 heterocyclic carboxylic Chemical class 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- UNELDXFWWQRODL-IUODEOHRSA-N (6ar,10ar)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline Chemical class C1=CC([C@H]2CCCN([C@@H]2C2)C)=C3C2=CN(C)C3=C1 UNELDXFWWQRODL-IUODEOHRSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000002908 adrenolytic effect Effects 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000002196 ecbolic effect Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical compound OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 abstract 1
- 150000003568 thioethers Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1768466 | 1966-07-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1138419A true GB1138419A (en) | 1969-01-01 |
Family
ID=11150550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3388767A Expired GB1138419A (en) | 1966-07-29 | 1967-07-24 | Ergoline derivatives |
Country Status (4)
| Country | Link |
|---|---|
| CH (1) | CH503731A (en:Method) |
| FR (1) | FR6785M (en:Method) |
| GB (1) | GB1138419A (en:Method) |
| NL (1) | NL6710210A (en:Method) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0411494A3 (en) * | 1989-08-04 | 1991-04-24 | Poli Industria Chimica S.P.A. | Ergoline derivatives having dopaminergic activity |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2112382B (en) * | 1981-11-06 | 1985-03-06 | Erba Farmitalia | Ergoline derivatives |
-
1967
- 1967-07-24 NL NL6710210A patent/NL6710210A/xx unknown
- 1967-07-24 GB GB3388767A patent/GB1138419A/en not_active Expired
- 1967-07-26 FR FR115719A patent/FR6785M/fr not_active Expired
- 1967-07-28 CH CH1071767A patent/CH503731A/de not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0411494A3 (en) * | 1989-08-04 | 1991-04-24 | Poli Industria Chimica S.P.A. | Ergoline derivatives having dopaminergic activity |
Also Published As
| Publication number | Publication date |
|---|---|
| FR6785M (en:Method) | 1969-03-17 |
| NL6710210A (en:Method) | 1968-01-30 |
| CH503731A (de) | 1971-02-28 |
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