GB1102905A - Method for producing ª‡-keto glutaric acid by fermentation - Google Patents

Method for producing ª‡-keto glutaric acid by fermentation

Info

Publication number
GB1102905A
GB1102905A GB2813865A GB2813865A GB1102905A GB 1102905 A GB1102905 A GB 1102905A GB 2813865 A GB2813865 A GB 2813865A GB 2813865 A GB2813865 A GB 2813865A GB 1102905 A GB1102905 A GB 1102905A
Authority
GB
United Kingdom
Prior art keywords
glutaric acid
keto glutaric
paraffin
medium
nutrient medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2813865A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of GB1102905A publication Critical patent/GB1102905A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/50—Polycarboxylic acids having keto groups, e.g. 2-ketoglutaric acid

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

a -Keto glutaric acid is produced by the aerobic culturing of a microorganism of a strain capable of producing a -keto glutaric acid in a nutrient medium containing a C10- 25 n-paraffin or a C10- 25 n-paraffin-containing petroleum fraction, the medium being stirred and its pH being maintained at 5-8, accumulating a -keto glutaric acid in the medium and separating the acid so produced. Preferred strains are those of the genera Corynebacterium, Brevibacterium, Anthrobacter and Micrococcus. The nutrient medium may also include a source of nitrogen, e.g. ammonium salts or urea, and organic nutrients, e.g. peptones, corn steep liquors, meat extracts, hydrolysates of soybean meals, yeast extracts, amino acids, organic nucleic bases, and vitamins, e.g. thiamine. It is preferred to include calcium carbonate in the nutrient medium. In examples, dodecane, C12- 14 and C11- 19 n-paraffin mixtures and kerosene are used as the carbon source.
GB2813865A 1964-07-10 1965-07-02 Method for producing ª‡-keto glutaric acid by fermentation Expired GB1102905A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3892164 1964-07-10

Publications (1)

Publication Number Publication Date
GB1102905A true GB1102905A (en) 1968-02-14

Family

ID=12538666

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2813865A Expired GB1102905A (en) 1964-07-10 1965-07-02 Method for producing ª‡-keto glutaric acid by fermentation

Country Status (3)

Country Link
DE (1) DE1442259A1 (en)
FR (1) FR1451390A (en)
GB (1) GB1102905A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007051451A1 (en) 2007-10-27 2009-04-30 Evonik Degussa Gmbh Microbial reaction system, useful for the fermentative preparation of alpha-ketoglutaric acid, comprises recombinant microorganism and reaction medium, where an inactivation of the glutamate dehydrogenase is present in the microorganism
DE102007051452A1 (en) 2007-10-27 2009-04-30 Evonik Degussa Gmbh Microbial reaction system, useful for the fermentative preparation of alpha-ketoglutaric acid, comprises recombinant microorganism and reaction medium, where an inactivation of the glutamate dehydrogenase is present in the microorganism

Also Published As

Publication number Publication date
DE1442259A1 (en) 1969-07-10
FR1451390A (en) 1966-09-02

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