GB1096732A - Novel 16-alkyl-steroids - Google Patents
Novel 16-alkyl-steroidsInfo
- Publication number
- GB1096732A GB1096732A GB727765A GB727765A GB1096732A GB 1096732 A GB1096732 A GB 1096732A GB 727765 A GB727765 A GB 727765A GB 727765 A GB727765 A GB 727765A GB 1096732 A GB1096732 A GB 1096732A
- Authority
- GB
- United Kingdom
- Prior art keywords
- keto
- reduction
- ones
- formula
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000006722 reduction reaction Methods 0.000 abstract 3
- 239000004215 Carbon black (E152) Substances 0.000 abstract 2
- 229930195733 hydrocarbon Natural products 0.000 abstract 2
- -1 hydrocarbon radical Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 2
- 230000009466 transformation Effects 0.000 abstract 2
- 238000000844 transformation Methods 0.000 abstract 2
- 238000006027 Birch reduction reaction Methods 0.000 abstract 1
- 229930194542 Keto Natural products 0.000 abstract 1
- 150000001335 aliphatic alkanes Chemical class 0.000 abstract 1
- 150000001336 alkenes Chemical class 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 150000002084 enol ethers Chemical class 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000003431 oxalo group Chemical group 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 230000002829 reductive effect Effects 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL6402049A NL6402049A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1964-02-29 | 1964-02-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1096732A true GB1096732A (en) | 1967-12-29 |
Family
ID=19789441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB727765A Expired GB1096732A (en) | 1964-02-29 | 1965-02-19 | Novel 16-alkyl-steroids |
Country Status (8)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4082780A (en) * | 1975-11-27 | 1978-04-04 | Takeda Chemical Industries, Ltd. | Estradiol derivatives |
| US8003783B2 (en) | 2003-03-24 | 2011-08-23 | Sterix Limited | 17B-hydroxysteroid dehydrogenase inhibitors |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2100319C3 (de) * | 1970-01-07 | 1974-10-31 | Takeda Chemical Industries, Ltd., Osaka (Japan) | Neue Östranverbindungen, ihre Herstellung und sie enthaltende Arzneimittel |
-
1964
- 1964-02-29 NL NL6402049A patent/NL6402049A/xx unknown
-
1965
- 1965-02-19 GB GB727765A patent/GB1096732A/en not_active Expired
- 1965-02-24 CH CH249865A patent/CH495965A/de not_active IP Right Cessation
- 1965-02-26 BE BE660312D patent/BE660312A/ unknown
- 1965-02-26 BR BR16756665A patent/BR6567566D0/pt unknown
- 1965-02-26 DE DE1965N0026296 patent/DE1543266A1/de active Pending
- 1965-02-27 FR FR7317A patent/FR1453828A/fr not_active Expired
- 1965-03-01 DK DK104865A patent/DK116508B/da unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4082780A (en) * | 1975-11-27 | 1978-04-04 | Takeda Chemical Industries, Ltd. | Estradiol derivatives |
| US8003783B2 (en) | 2003-03-24 | 2011-08-23 | Sterix Limited | 17B-hydroxysteroid dehydrogenase inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| BE660312A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1965-08-26 |
| BR6567566D0 (pt) | 1973-08-02 |
| DK116508B (da) | 1970-01-19 |
| NL6402049A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1965-08-30 |
| FR1453828A (fr) | 1966-09-30 |
| CH495965A (de) | 1970-09-15 |
| DE1543266A1 (de) | 1969-11-06 |
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