GB1070593A - Ophthalmic ointment composition and the preparation thereof - Google Patents

Ophthalmic ointment composition and the preparation thereof

Info

Publication number
GB1070593A
GB1070593A GB45791/63A GB4579163A GB1070593A GB 1070593 A GB1070593 A GB 1070593A GB 45791/63 A GB45791/63 A GB 45791/63A GB 4579163 A GB4579163 A GB 4579163A GB 1070593 A GB1070593 A GB 1070593A
Authority
GB
United Kingdom
Prior art keywords
preparation
polyethylene
ophthalmic ointment
ointment composition
acetonide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB45791/63A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olin Corp
Original Assignee
Olin Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olin Corp filed Critical Olin Corp
Publication of GB1070593A publication Critical patent/GB1070593A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Abstract

An ointment base, particularly for ophthalmic use comprises an intimate mixture of yellow soft paraffin (30-70% by weight) liquid paraffin (25-70%) and polyethylene (0.1-5%). Preferably, it is made by a process involving a "quick cooling" step, e.g. the polyethylene and at least some of the mineral oil are intermixed at 80-120 DEG C. and "quick-cooled" before being mixed with the remaining ingredients. Medicaments may be incorporated into the base e.g. anti-inflammatory agents such as triamcinolone acetonide or 6a -fluoro-triamcinolane acetonide; bactericidal agents e.g. neomycin or gramicidin; and surface anaesthetics e.g. proparacaine hydrochloride.
GB45791/63A 1962-12-26 1963-11-20 Ophthalmic ointment composition and the preparation thereof Expired GB1070593A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24733362A 1962-12-26 1962-12-26

Publications (1)

Publication Number Publication Date
GB1070593A true GB1070593A (en) 1967-06-01

Family

ID=22934517

Family Applications (1)

Application Number Title Priority Date Filing Date
GB45791/63A Expired GB1070593A (en) 1962-12-26 1963-11-20 Ophthalmic ointment composition and the preparation thereof

Country Status (2)

Country Link
FR (1) FR3377M (en)
GB (1) GB1070593A (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2208645A2 (en) * 1972-11-30 1974-06-28 Pharmacia Ab
US3968201A (en) 1972-11-30 1976-07-06 Pharmacia Aktiebolag Dosage unit containing a substance showing a topical effect on the eye, and a method of preparing same
EP0608419A1 (en) * 1991-09-18 1994-08-03 Fujisawa Pharmaceutical Co., Ltd. Transocular preparation
EP0630254A1 (en) * 1992-12-08 1994-12-28 Deo Corporation Method of ophthalmic drug delivery
EP0693932A1 (en) * 1993-03-19 1996-01-31 Cellegy Pharmaceuticals, Inc. Methods and compositions for inducing phase separation of epithelial lipid bilayers
US5830508A (en) * 1992-08-06 1998-11-03 Deo Corporation Composition for treating dry eye
US6562606B1 (en) 1993-03-19 2003-05-13 The Regents Of The University Of California Methods and compositions for disrupting the epithelial barrier function

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2208645A2 (en) * 1972-11-30 1974-06-28 Pharmacia Ab
US3968201A (en) 1972-11-30 1976-07-06 Pharmacia Aktiebolag Dosage unit containing a substance showing a topical effect on the eye, and a method of preparing same
EP0608419A1 (en) * 1991-09-18 1994-08-03 Fujisawa Pharmaceutical Co., Ltd. Transocular preparation
EP0608419A4 (en) * 1991-09-18 1995-01-11 Fujisawa Pharmaceutical Co Transocular preparation.
US6254893B1 (en) 1992-08-06 2001-07-03 Deo Corporation Composition for treating dry eye
US5830508A (en) * 1992-08-06 1998-11-03 Deo Corporation Composition for treating dry eye
EP0630254A4 (en) * 1992-12-08 1997-01-15 Deo Corp Method of ophthalmic drug delivery.
EP0879601A2 (en) * 1992-12-08 1998-11-25 Deo Corporation Ophthalmic drug delivery system
EP0879601A3 (en) * 1992-12-08 2000-08-30 Deo Corporation Ophthalmic drug delivery system
EP0630254A1 (en) * 1992-12-08 1994-12-28 Deo Corporation Method of ophthalmic drug delivery
EP0693932A1 (en) * 1993-03-19 1996-01-31 Cellegy Pharmaceuticals, Inc. Methods and compositions for inducing phase separation of epithelial lipid bilayers
EP0693932A4 (en) * 1993-03-19 2000-06-14 Cellegy Pharma Inc Methods and compositions for inducing phase separation of epithelial lipid bilayers
US6562606B1 (en) 1993-03-19 2003-05-13 The Regents Of The University Of California Methods and compositions for disrupting the epithelial barrier function

Also Published As

Publication number Publication date
FR3377M (en) 1965-06-14

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