FR3060859B1 - Bio-electrode pour la detection et/ou l'oxydation du glucose et son procede de fabrication et dispositif la comprenant. - Google Patents

Bio-electrode pour la detection et/ou l'oxydation du glucose et son procede de fabrication et dispositif la comprenant. Download PDF

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Publication number
FR3060859B1
FR3060859B1 FR1662997A FR1662997A FR3060859B1 FR 3060859 B1 FR3060859 B1 FR 3060859B1 FR 1662997 A FR1662997 A FR 1662997A FR 1662997 A FR1662997 A FR 1662997A FR 3060859 B1 FR3060859 B1 FR 3060859B1
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FR
France
Prior art keywords
same
glucose
oxidation
detection
bio electrode
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1662997A
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English (en)
Other versions
FR3060859A1 (fr
Inventor
Fabien GIROUD
Andrew Gross
Serge Cosnier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite Grenoble Alpes
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite Grenoble Alpes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Universite Grenoble Alpes filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR1662997A priority Critical patent/FR3060859B1/fr
Priority to CA3047525A priority patent/CA3047525C/fr
Priority to PCT/FR2017/053689 priority patent/WO2018115710A1/fr
Priority to US16/471,319 priority patent/US11337627B2/en
Priority to EP17832514.8A priority patent/EP3560021B1/fr
Priority to ES17832514T priority patent/ES2867898T3/es
Publication of FR3060859A1 publication Critical patent/FR3060859A1/fr
Application granted granted Critical
Publication of FR3060859B1 publication Critical patent/FR3060859B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01M—PROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
    • H01M8/00—Fuel cells; Manufacture thereof
    • H01M8/16—Biochemical fuel cells, i.e. cells in which microorganisms function as catalysts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0209—Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01M—PROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
    • H01M4/00—Electrodes
    • H01M4/86—Inert electrodes with catalytic activity, e.g. for fuel cells
    • H01M4/90—Selection of catalytic material
    • H01M4/9008—Organic or organo-metallic compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/30—Hydrogen technology
    • Y02E60/50—Fuel cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P70/00—Climate change mitigation technologies in the production process for final industrial or consumer products
    • Y02P70/50—Manufacturing or production processes characterised by the final manufactured product

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Electrochemistry (AREA)
  • Zoology (AREA)
  • Sustainable Development (AREA)
  • Sustainable Energy (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Manufacturing & Machinery (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Inert Electrodes (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Carbon And Carbon Compounds (AREA)

Abstract

L'invention concerne une bioélectrode et un dispositif la comprenant, pour la détection ou l'oxydation du glucose. La bioélectrode de l'invention comprend une couche de nanotubes de carbone auxquels des molécules aromatiques sont liées, et des enzymes FAD-GDH étant adsorbées aux molécules aromatiques. L'invention trouve application dans le domaine des biocapteurs et des biopiles à combustible, en particulier.
FR1662997A 2016-12-21 2016-12-21 Bio-electrode pour la detection et/ou l'oxydation du glucose et son procede de fabrication et dispositif la comprenant. Expired - Fee Related FR3060859B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR1662997A FR3060859B1 (fr) 2016-12-21 2016-12-21 Bio-electrode pour la detection et/ou l'oxydation du glucose et son procede de fabrication et dispositif la comprenant.
CA3047525A CA3047525C (fr) 2016-12-21 2017-12-19 Bio-electrode pour la detection et/ou l'oxydation du glucose et son procede de fabrication et dispositif la comprenant
PCT/FR2017/053689 WO2018115710A1 (fr) 2016-12-21 2017-12-19 Bio-electrode pour la detection et/ou l'oxydation du glucose et son procede de fabrication et dispositif la comprenant
US16/471,319 US11337627B2 (en) 2016-12-21 2017-12-19 Bioelectrode for detection and/or oxidation of glucose, its production method and device
EP17832514.8A EP3560021B1 (fr) 2016-12-21 2017-12-19 Bio-électrode pour la détection et/ou l'oxydation du glucose et son procédé de fabrication et dispositif la comprenant
ES17832514T ES2867898T3 (es) 2016-12-21 2017-12-19 Bioelectrodo para la detección y/u oxidación de glucosa, su método de producción y dispositivo

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1662997A FR3060859B1 (fr) 2016-12-21 2016-12-21 Bio-electrode pour la detection et/ou l'oxydation du glucose et son procede de fabrication et dispositif la comprenant.
FR1662997 2016-12-21

Publications (2)

Publication Number Publication Date
FR3060859A1 FR3060859A1 (fr) 2018-06-22
FR3060859B1 true FR3060859B1 (fr) 2019-05-31

Family

ID=58737649

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1662997A Expired - Fee Related FR3060859B1 (fr) 2016-12-21 2016-12-21 Bio-electrode pour la detection et/ou l'oxydation du glucose et son procede de fabrication et dispositif la comprenant.

Country Status (6)

Country Link
US (1) US11337627B2 (fr)
EP (1) EP3560021B1 (fr)
CA (1) CA3047525C (fr)
ES (1) ES2867898T3 (fr)
FR (1) FR3060859B1 (fr)
WO (1) WO2018115710A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3079073B1 (fr) * 2018-03-16 2024-03-01 Centre Nat Rech Scient Bioelectrode nanostructuree pour l'oxydation du glucose a partir de composes aromatiques electrogeneres
CA3180461A1 (fr) 2020-06-01 2021-12-09 Gambro Lundia Ab Systeme et methode de traitement du sang extracorporel
FR3150700A1 (fr) 2023-07-06 2025-01-10 Commissariat A L'energie Atomique Et Aux Energies Alternatives Dispositif de type patch micro-aiguilles à bioélectrode intégrée
FR3150909A1 (fr) 2023-07-07 2025-01-10 Centre National De La Recherche Scientifique Fabrication d'électrodes en graphite pop-corn pour l'électronique et la bioélectronique
CN117402195B (zh) * 2023-09-13 2026-03-03 浙江晟格生物科技有限公司 一种促进氧气传质生产麦芽糖酸的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7955559B2 (en) * 2005-11-15 2011-06-07 Nanomix, Inc. Nanoelectronic electrochemical test device
US7638228B2 (en) * 2002-11-27 2009-12-29 Saint Louis University Enzyme immobilization for use in biofuel cells and sensors
WO2014160210A1 (fr) * 2013-03-13 2014-10-02 The Regents Of The University Of Michigan Procédé pour déterminer la concentration en glucose des larmes à l'aide des bâtonnets diagnostiques de la glycémie
EP3249050B1 (fr) * 2016-05-23 2019-01-23 ARKRAY, Inc. Électrode à enzyme et biodétecteur l'utilisant

Also Published As

Publication number Publication date
EP3560021A1 (fr) 2019-10-30
CA3047525A1 (fr) 2018-06-28
CA3047525C (fr) 2024-04-30
US11337627B2 (en) 2022-05-24
WO2018115710A1 (fr) 2018-06-28
ES2867898T3 (es) 2021-10-21
EP3560021B1 (fr) 2021-01-27
US20190328288A1 (en) 2019-10-31
FR3060859A1 (fr) 2018-06-22

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