FR3047012B1 - PRIMARY CELL MICROCAPSULE - Google Patents
PRIMARY CELL MICROCAPSULE Download PDFInfo
- Publication number
- FR3047012B1 FR3047012B1 FR1650638A FR1650638A FR3047012B1 FR 3047012 B1 FR3047012 B1 FR 3047012B1 FR 1650638 A FR1650638 A FR 1650638A FR 1650638 A FR1650638 A FR 1650638A FR 3047012 B1 FR3047012 B1 FR 3047012B1
- Authority
- FR
- France
- Prior art keywords
- primary cell
- microcapsule
- cell microcapsule
- present
- liquid core
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003094 microcapsule Substances 0.000 title abstract 3
- 239000007788 liquid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/067—Hepatocytes
- C12N5/0671—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/16—Particles; Beads; Granular material; Encapsulation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0012—Cell encapsulation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2513/00—3D culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/74—Alginate
Abstract
La présente invention concerne une microcapsule comprenant au moins une cellule primaire de type II étant formée d'un cœur liquide et d'une enveloppe gélifiée encapsulant le cœur liquide. La présente invention concerne en outre l'utilisation de cette microcapsule pour la culture in vitro 3D, la fabrication d'organe artificiel, le criblage de composés tests.The present invention relates to a microcapsule comprising at least one type II primary cell being formed of a liquid core and a gelled envelope encapsulating the liquid core. The present invention further relates to the use of this microcapsule for 3D in vitro culture, the manufacture of artificial organs, the screening of test compounds.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1650638A FR3047012B1 (en) | 2016-01-26 | 2016-01-26 | PRIMARY CELL MICROCAPSULE |
PCT/FR2017/050178 WO2017129907A1 (en) | 2016-01-26 | 2017-01-26 | Microcapsule containing primary cells |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1650638A FR3047012B1 (en) | 2016-01-26 | 2016-01-26 | PRIMARY CELL MICROCAPSULE |
Publications (2)
Publication Number | Publication Date |
---|---|
FR3047012A1 FR3047012A1 (en) | 2017-07-28 |
FR3047012B1 true FR3047012B1 (en) | 2020-07-31 |
Family
ID=56008680
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1650638A Active FR3047012B1 (en) | 2016-01-26 | 2016-01-26 | PRIMARY CELL MICROCAPSULE |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR3047012B1 (en) |
WO (1) | WO2017129907A1 (en) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2939012B1 (en) * | 2008-12-01 | 2015-03-27 | Capsum | PROCESS FOR MANUFACTURING A SERIES OF CAPSULES, AND ASSOCIATED SERIES OF CAPSULES |
FR2986165B1 (en) * | 2012-01-31 | 2015-07-24 | Capsum | PROCESS FOR PREPARING RIGIDIFIED CAPSULES |
FR3014691B1 (en) * | 2013-12-13 | 2016-02-05 | Ets Francais Du Sang | CAPSULES CONTAINING CELLS WITH HEMATOPOIETIC POTENTIALITY |
-
2016
- 2016-01-26 FR FR1650638A patent/FR3047012B1/en active Active
-
2017
- 2017-01-26 WO PCT/FR2017/050178 patent/WO2017129907A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2017129907A1 (en) | 2017-08-03 |
FR3047012A1 (en) | 2017-07-28 |
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Legal Events
Date | Code | Title | Description |
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PLFP | Fee payment |
Year of fee payment: 2 |
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PLSC | Publication of the preliminary search report |
Effective date: 20170728 |
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PLFP | Fee payment |
Year of fee payment: 3 |
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TQ | Partial transmission of property |
Owner name: CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE, FR Effective date: 20180622 Owner name: ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDU, FR Effective date: 20180622 |
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PLFP | Fee payment |
Year of fee payment: 5 |
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PLFP | Fee payment |
Year of fee payment: 6 |
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PLFP | Fee payment |
Year of fee payment: 7 |
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PLFP | Fee payment |
Year of fee payment: 8 |
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PLFP | Fee payment |
Year of fee payment: 9 |