FR2896245B1 - Nouveaux derives de chalcone, a activite antimitotique - Google Patents

Nouveaux derives de chalcone, a activite antimitotique

Info

Publication number
FR2896245B1
FR2896245B1 FR0600389A FR0600389A FR2896245B1 FR 2896245 B1 FR2896245 B1 FR 2896245B1 FR 0600389 A FR0600389 A FR 0600389A FR 0600389 A FR0600389 A FR 0600389A FR 2896245 B1 FR2896245 B1 FR 2896245B1
Authority
FR
France
Prior art keywords
chalcone derivatives
antimitotic activity
new chalcone
new
antimitotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0600389A
Other languages
English (en)
Other versions
FR2896245A1 (fr
Inventor
Ahcene Boumendjel
Charles Dumontet
Madeleine Blanc
Anne Marie Mariotte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Claude Bernard Lyon 1 UCBL
Universite Joseph Fourier Grenoble 1
Original Assignee
Universite Claude Bernard Lyon 1 UCBL
Universite Joseph Fourier Grenoble 1
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Claude Bernard Lyon 1 UCBL, Universite Joseph Fourier Grenoble 1 filed Critical Universite Claude Bernard Lyon 1 UCBL
Priority to FR0600389A priority Critical patent/FR2896245B1/fr
Priority to PCT/FR2007/050654 priority patent/WO2007083060A2/fr
Priority to US12/087,790 priority patent/US20090182058A1/en
Priority to EP07718039A priority patent/EP1976818A2/fr
Publication of FR2896245A1 publication Critical patent/FR2896245A1/fr
Application granted granted Critical
Publication of FR2896245B1 publication Critical patent/FR2896245B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/835—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups having unsaturation outside an aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/22—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR0600389A 2006-01-17 2006-01-17 Nouveaux derives de chalcone, a activite antimitotique Expired - Fee Related FR2896245B1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR0600389A FR2896245B1 (fr) 2006-01-17 2006-01-17 Nouveaux derives de chalcone, a activite antimitotique
PCT/FR2007/050654 WO2007083060A2 (fr) 2006-01-17 2007-01-15 Derives de chalcone a activite antimitotique
US12/087,790 US20090182058A1 (en) 2006-01-17 2007-01-15 Novel Chalcone Derivatives With Antimitotic Activity
EP07718039A EP1976818A2 (fr) 2006-01-17 2007-01-15 Derives de chalcone a activite antimitotique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0600389A FR2896245B1 (fr) 2006-01-17 2006-01-17 Nouveaux derives de chalcone, a activite antimitotique

Publications (2)

Publication Number Publication Date
FR2896245A1 FR2896245A1 (fr) 2007-07-20
FR2896245B1 true FR2896245B1 (fr) 2010-09-17

Family

ID=36950357

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0600389A Expired - Fee Related FR2896245B1 (fr) 2006-01-17 2006-01-17 Nouveaux derives de chalcone, a activite antimitotique

Country Status (4)

Country Link
US (1) US20090182058A1 (fr)
EP (1) EP1976818A2 (fr)
FR (1) FR2896245B1 (fr)
WO (1) WO2007083060A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011009826A2 (fr) * 2009-07-21 2011-01-27 ADAMED Sp.z o.o. Nouveaux dérivés de chalcone présentant une activité cytotoxique
KR101283004B1 (ko) * 2011-10-17 2013-07-05 건국대학교 산학협력단 벤조칼콘을 유효성분으로 포함하는 항암제 조성물
KR101333734B1 (ko) * 2011-10-13 2013-11-28 건국대학교 산학협력단 벤조히드록시메톡시칼콘을 유효성분으로 포함하는 항암제 조성물
KR101290578B1 (ko) 2011-10-25 2013-07-30 건국대학교 산학협력단 히드록시메톡시벤조칼콘 화합물을 유효성분으로 포함하는 항암용 조성물
KR101333736B1 (ko) * 2011-10-25 2013-11-27 건국대학교 산학협력단 히드록시메톡시칼콘 화합물을 유효성분으로 포함하는 항암용 조성물
KR101290579B1 (ko) * 2011-10-25 2013-07-30 건국대학교 산학협력단 벤조칼콘을 유효성분으로 포함하는 항암제 조성물
US10865176B2 (en) * 2012-12-21 2020-12-15 The Chinese University Of Hong Kong Small molecule modulators of microRNA-34a
CN103877069B (zh) * 2012-12-21 2017-01-04 香港中文大学 微RNA‑34a的小分子调节剂
FR3004180B1 (fr) 2013-04-05 2015-06-26 Univ Claude Bernard Lyon Nouveaux derives de chalcone presentant une activite anti-allergique
CN114409522B (zh) * 2022-03-01 2023-08-15 贵州省天然产物研究中心 一种查尔酮衍生物及其制备方法与用途
CN115433073B (zh) * 2022-08-15 2024-04-19 兰州大学 一种卡瓦胡椒素b类似物的制备方法及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2250464A1 (fr) * 1996-03-29 1997-10-09 G.D. Searle & Co. Derives de phenylene meta-substitues, utilises comme antagonistes ou inhibiteurs de l'integrine alphavbeta3
EP0998939A1 (fr) * 1998-09-09 2000-05-10 The School Of Pharmacy, University Of London Extraits de plantes à base de chalcone utilisables en thérapie
CA2395191A1 (fr) * 1999-12-23 2001-06-28 Tedman Ehlers Chalcone et ses analogues comme agents inhibiteurs de l'angiogenese et des etats pathologiques associes

Also Published As

Publication number Publication date
EP1976818A2 (fr) 2008-10-08
WO2007083060A3 (fr) 2007-09-13
FR2896245A1 (fr) 2007-07-20
WO2007083060A2 (fr) 2007-07-26
US20090182058A1 (en) 2009-07-16

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20130930