FR2818549B1 - Composition pharmaceutique solide thermoformable pour la liberation controlee de trimetazidine - Google Patents

Composition pharmaceutique solide thermoformable pour la liberation controlee de trimetazidine

Info

Publication number
FR2818549B1
FR2818549B1 FR0017014A FR0017014A FR2818549B1 FR 2818549 B1 FR2818549 B1 FR 2818549B1 FR 0017014 A FR0017014 A FR 0017014A FR 0017014 A FR0017014 A FR 0017014A FR 2818549 B1 FR2818549 B1 FR 2818549B1
Authority
FR
France
Prior art keywords
trimetazidine
pharmaceutical composition
controlled release
solid thermoformable
thermoformable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0017014A
Other languages
English (en)
Other versions
FR2818549A1 (fr
Inventor
Patrick Wuthrich
Herve Rolland
Gilles Briault
Gerald Pichon
Francois Tharrault
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier
Original Assignee
Laboratoires Servier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier filed Critical Laboratoires Servier
Priority to FR0017014A priority Critical patent/FR2818549B1/fr
Publication of FR2818549A1 publication Critical patent/FR2818549A1/fr
Application granted granted Critical
Publication of FR2818549B1 publication Critical patent/FR2818549B1/fr
Application status is Expired - Fee Related legal-status Critical
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
FR0017014A 2000-12-26 2000-12-26 Composition pharmaceutique solide thermoformable pour la liberation controlee de trimetazidine Expired - Fee Related FR2818549B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR0017014A FR2818549B1 (fr) 2000-12-26 2000-12-26 Composition pharmaceutique solide thermoformable pour la liberation controlee de trimetazidine

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR0017014A FR2818549B1 (fr) 2000-12-26 2000-12-26 Composition pharmaceutique solide thermoformable pour la liberation controlee de trimetazidine
PCT/FR2001/004132 WO2002051417A1 (fr) 2000-12-26 2001-12-21 Composition pharmaceutique solide thermoformable pour la liberation contrôlee de trimetazidine
ARP010106029 AR032049A1 (es) 2000-12-26 2001-12-26 Una composicion farmaceutica solida termoformable para la liberacion controlada de trimetazidina
ARP010106026 AR031970A1 (es) 2000-12-26 2001-12-26 Composicion farmaceutica solida termoformable para la liberacion controlada de ivabradina

Publications (2)

Publication Number Publication Date
FR2818549A1 FR2818549A1 (fr) 2002-06-28
FR2818549B1 true FR2818549B1 (fr) 2003-02-07

Family

ID=8858189

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0017014A Expired - Fee Related FR2818549B1 (fr) 2000-12-26 2000-12-26 Composition pharmaceutique solide thermoformable pour la liberation controlee de trimetazidine

Country Status (3)

Country Link
AR (2) AR032049A1 (fr)
FR (1) FR2818549B1 (fr)
WO (1) WO2002051417A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2885807B1 (fr) * 2005-05-18 2008-05-16 Mg Pharma Composition pharmaceutique solide a liberation prolongee de 1-(2,3,4-trimethoxybenzyl) piperazine, et procede de preparation
WO2009066315A2 (fr) * 2007-08-08 2009-05-28 Usv Limited Compositions à libération prolongée de trimétazidine et procédé de préparation
WO2009034541A2 (fr) * 2007-09-11 2009-03-19 Ranbaxy Laboratories Limited Formes galéniques à libération contrôlée à base de trimétazidine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2490963B1 (fr) * 1980-09-30 1986-04-18 Science Union & Cie Nouvelle composition therapeutique a action anti-ischemique contenant de la trimethoxy 2, 3, 4-benzyl 1-piperazine
JPH0625055B2 (ja) * 1985-03-18 1994-04-06 日本ケミフア株式会社 持続性錠剤
DE4138513A1 (de) * 1991-11-23 1993-05-27 Basf Ag Feste pharmazeutische retardform
FR2717687B1 (fr) * 1994-03-24 1996-06-14 Adir Compositions pharmaceutiques permettant la libération prolongée de trimétazidine après administration par voie orale.
US5965161A (en) * 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates

Also Published As

Publication number Publication date
WO2002051417A1 (fr) 2002-07-04
AR032049A1 (es) 2003-10-22
FR2818549A1 (fr) 2002-06-28
AR031970A1 (es) 2003-10-08

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Legal Events

Date Code Title Description
ST Notification of lapse