FR2769629B1 - 8-AZABICYCLO [3.2.1] OCTANE-3-METHANAMINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION - Google Patents

8-AZABICYCLO [3.2.1] OCTANE-3-METHANAMINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Info

Publication number
FR2769629B1
FR2769629B1 FR9712583A FR9712583A FR2769629B1 FR 2769629 B1 FR2769629 B1 FR 2769629B1 FR 9712583 A FR9712583 A FR 9712583A FR 9712583 A FR9712583 A FR 9712583A FR 2769629 B1 FR2769629 B1 FR 2769629B1
Authority
FR
France
Prior art keywords
azabicyclo
octane
preparation
therapeutic application
methanamine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9712583A
Other languages
French (fr)
Other versions
FR2769629A1 (en
Inventor
Mireille Sevrin
Peretti Daniele De
Benoit Marabout
Jocelyne Roy
David Machnik
Pascal George
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR9712583A priority Critical patent/FR2769629B1/en
Priority to UA2000041930A priority patent/UA58476C2/en
Priority to ARP980104978A priority patent/AR017300A1/en
Priority to EP98947615A priority patent/EP1021442B1/en
Priority to IL13552098A priority patent/IL135520A0/en
Priority to CA002305468A priority patent/CA2305468C/en
Priority to CNB988119404A priority patent/CN1140526C/en
Priority to BR9812752-7A priority patent/BR9812752A/en
Priority to CZ20001278A priority patent/CZ290679B6/en
Priority to NZ503829A priority patent/NZ503829A/en
Priority to RU2000109298/04A priority patent/RU2203281C2/en
Priority to TR2000/00942T priority patent/TR200000942T2/en
Priority to PL98339764A priority patent/PL186998B1/en
Priority to ES98947615T priority patent/ES2171306T3/en
Priority to AT98947615T priority patent/ATE212631T1/en
Priority to SK504-2000A priority patent/SK283080B6/en
Priority to HU0102086A priority patent/HUP0102086A3/en
Priority to AU94468/98A priority patent/AU746935B2/en
Priority to KR1020007003811A priority patent/KR20010015717A/en
Priority to PCT/FR1998/002137 priority patent/WO1999019325A1/en
Priority to SI9830132T priority patent/SI1021442T1/en
Priority to DK98947615T priority patent/DK1021442T3/en
Priority to EEP200000207A priority patent/EE04347B1/en
Priority to PT98947615T priority patent/PT1021442E/en
Priority to US09/529,077 priority patent/US6221879B1/en
Priority to JP2000515897A priority patent/JP4505135B2/en
Priority to DE69803689T priority patent/DE69803689T2/en
Priority to CO98058540A priority patent/CO5011097A1/en
Priority to TW087116738A priority patent/TW444014B/en
Publication of FR2769629A1 publication Critical patent/FR2769629A1/en
Application granted granted Critical
Publication of FR2769629B1 publication Critical patent/FR2769629B1/en
Priority to IL135520A priority patent/IL135520A/en
Priority to BG104309A priority patent/BG64859B1/en
Priority to NO20001810A priority patent/NO325170B1/en
Priority to HK00107648A priority patent/HK1029108A1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
FR9712583A 1997-10-09 1997-10-09 8-AZABICYCLO [3.2.1] OCTANE-3-METHANAMINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION Expired - Fee Related FR2769629B1 (en)

Priority Applications (33)

Application Number Priority Date Filing Date Title
FR9712583A FR2769629B1 (en) 1997-10-09 1997-10-09 8-AZABICYCLO [3.2.1] OCTANE-3-METHANAMINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
UA2000041930A UA58476C2 (en) 1997-10-09 1998-07-10 8-AZABICYCLO[3.2.1]OCTANE-3-METHANAMINE DERIVATIVES, ITS PREPARATION AND APPLICATION IN therapeutics
ARP980104978A AR017300A1 (en) 1997-10-09 1998-10-06 A COMPOSITE DERIVED FROM 8-AZABICICLO [3.2.1] OCTAN-3-METHANAMINE, AND A MEDICINAL PRODUCT AND A PHARMACEUTICAL COMPOSITION THAT INCLUDES THAT DERIVATIVE.
SI9830132T SI1021442T1 (en) 1997-10-09 1998-10-07 8-azabicyclo 3.2.1) octane-3-methanamine derivatives as ligands of d2 and d3 dopamine and 5ht1a and 5ht2 serotonin receptors
CA002305468A CA2305468C (en) 1997-10-09 1998-10-07 8-azabicyclo [3.2.1] octane-3-methanamine derivatives as ligands of d2 and d3 dopamine and 5ht1a and 5ht2 serotonin receptors
CNB988119404A CN1140526C (en) 1997-10-09 1998-10-07 8-Azabicyclo [3,2,1] octane-3-methanamine derivatives as ligands of D2 and D3 dopamine and 5HT1A and 5HT2 serotonin receptors
BR9812752-7A BR9812752A (en) 1997-10-09 1998-10-07 Derivatives of 8-azabicyclo [3.2.1] octane-3-methanamine as ligands for dopamine d2 and d3 receptors and serotonin 5ht1a and 5ht2
CZ20001278A CZ290679B6 (en) 1997-10-09 1998-10-07 Derivatives of 8-azabicyclo[3,2,1]octane-3-methanamine, process of their preparation and their therapeutic use
NZ503829A NZ503829A (en) 1997-10-09 1998-10-07 8-azabicyclo [3.2.1] octane-3-methanamine derivatives as ligands of D2 and D3 dopamine and 5HT1A and 5HT2 serotonin receptors
RU2000109298/04A RU2203281C2 (en) 1997-10-09 1998-10-07 Derivatives of 8-azabicyclo[3,2,1]octane-3-methan- amine as ligands of dopamine receptors d2 and d3 and serotonin receptors 5-ht1a and 5-ht2 and drug and pharmaceutical composition containing thereof
TR2000/00942T TR200000942T2 (en) 1997-10-09 1998-10-07 8-Azabisayklo (3.2.1) octane-3-methanamine derivatives, their preparation and therapeutic applications.
PL98339764A PL186998B1 (en) 1997-10-09 1998-10-07 Derivatives of azabicyclo[3.2.1]octane-3-methylamine as ligands of dopamine d2 and d3 as well as serotonin 5ht1a and 5ht2 receptors
ES98947615T ES2171306T3 (en) 1997-10-09 1998-10-07 COMPOSED UNDER THE FORM OF A PURE GEOMETRIC ISOMER OR A MIXTURE OF THESE ISOMERS.
AT98947615T ATE212631T1 (en) 1997-10-09 1998-10-07 8-AZABICYCLO(3.2.1)0CTAN-3-METHANAMENE DERIVATIVES AS LIGANDS OF THE DOPAMINE RECEPTORS D2 AND D3 AND THE SEROTONIN RECEPTORS 5HT1A AND 5HT2
SK504-2000A SK283080B6 (en) 1997-10-09 1998-10-07 8-azabicyclo[3.2.1]octane-3-methanamine derivatives, medicament and pharmaceutical composition
HU0102086A HUP0102086A3 (en) 1997-10-09 1998-10-07 8-azabicyclo[3.2.1]octane-3-methanamine derivatives and pharmaceutical compositions containing the same
EP98947615A EP1021442B1 (en) 1997-10-09 1998-10-07 8-azabicyclo 3.2.1] octane-3-methanamine derivatives as ligands of d2 and d3 dopamine and 5ht1a and 5ht2 serotonin receptors
KR1020007003811A KR20010015717A (en) 1997-10-09 1998-10-07 8-azabicyclo [3.2.1] octane-3-methanamine derivatives as ligands of d2 and d3 dopamine and 5ht1a and 5ht2 serotonin receptors
PCT/FR1998/002137 WO1999019325A1 (en) 1997-10-09 1998-10-07 8-azabicyclo [3.2.1] octane-3-methanamine derivatives as ligands of d2 and d3 dopamine and 5ht1a and 5ht2 serotonin receptors
IL13552098A IL135520A0 (en) 1997-10-09 1998-10-07 8-azabicyclo [3.2.1.] octane-3-methanamine derivatives, their preparation and their therapeutic application
DK98947615T DK1021442T3 (en) 1997-10-09 1998-10-07 Derivatives of 8-azabicyclo [3.2.1] octan-3-methanamine as ligands to the D2 and D3 dopamine receptors and the 5HT1A and 5HT2 serotonin receptors
EEP200000207A EE04347B1 (en) 1997-10-09 1998-10-07 8-Azabicyclo [3.2.1] octane-3-methanamine derivatives, medicament and pharmaceutical composition containing them
PT98947615T PT1021442E (en) 1997-10-09 1998-10-07 8-AZABICYCLO-3,2.1 | OCTANO-3-METHANAMINE DERIVATIVES AS DIGAMINE D2 AND D3 AND SEROTONIN 5HT1A AND 5HT2 RECEPTORS LIGANDS
US09/529,077 US6221879B1 (en) 1997-10-09 1998-10-07 8-azabicyclo[3.2.1] octane-3-methanamine derivatives as ligands of D2 and D3 dopamine and 5HT1A and 5HT2 serotonin receptors
JP2000515897A JP4505135B2 (en) 1997-10-09 1998-10-07 8-azabicyclo [3.2.1] octane-3-methanamine derivatives as ligands for the receptors of D2 and D3 dopamine and 5HT1A and 5HT2 serotonin
DE69803689T DE69803689T2 (en) 1997-10-09 1998-10-07 8-AZABICYCLO (3.2.1) 0CTAN-3-METHANAMINE DERIVATIVES AS LIGANDS OF THE DOPAMINE RECEPTORS D2 AND D3 AND THE SEROTONIN RECEPTORS 5HT1A AND 5HT2
AU94468/98A AU746935B2 (en) 1997-10-09 1998-10-07 8-azabicyclo (3.2.1) octane-3-methanamine derivatives as ligands of D2 and D3 dopamine and 5HT1A and 5HT2 serotonin receptors
CO98058540A CO5011097A1 (en) 1997-10-09 1998-10-08 DERIVATIVES OF 8-AZABICICLO [3.2.1] OCTAN-3-METHANAMINE.
TW087116738A TW444014B (en) 1997-10-09 1998-10-08 8-azabicyclo [3.2.1] octane-3-methanamine derivatives, their preparation and their therapeutic application
IL135520A IL135520A (en) 1997-10-09 2000-04-06 N-substituted 8-benz(o)yl-8-azabicyclo [3.2.1.] octane-3-methanamine derivatives, their preparation and pharmaceutical compositions containing them
BG104309A BG64859B1 (en) 1997-10-09 2000-04-07 8-azabicyclo[3,2,1]octane-3-methanamine derivatives as ligands of d2 and d3 dopamine and 5ht1a and 5ht2 serotonin receptors
NO20001810A NO325170B1 (en) 1997-10-09 2000-04-07 8-azabicyclo [3.2.1] octane-3-methanamine derivatives, drugs and pharmaceutical preparations
HK00107648A HK1029108A1 (en) 1997-10-09 2000-11-29 8-azabicyclo 3.2.1) octane-3-methanamine derivatives as ligands of d2 and d3 dopamine and 5ht1a and 5ht2 serotonin receptors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9712583A FR2769629B1 (en) 1997-10-09 1997-10-09 8-AZABICYCLO [3.2.1] OCTANE-3-METHANAMINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Publications (2)

Publication Number Publication Date
FR2769629A1 FR2769629A1 (en) 1999-04-16
FR2769629B1 true FR2769629B1 (en) 1999-11-12

Family

ID=9511997

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9712583A Expired - Fee Related FR2769629B1 (en) 1997-10-09 1997-10-09 8-AZABICYCLO [3.2.1] OCTANE-3-METHANAMINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Country Status (1)

Country Link
FR (1) FR2769629B1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI117964B (en) 2005-11-21 2007-05-15 Ensihoito Pekka Kilpelaeinen K Liquid collection device
US9125866B1 (en) 2015-01-28 2015-09-08 King Saud University Antidepressant compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4910302A (en) * 1988-12-19 1990-03-20 American Home Products Corporation Psychotropic polycyclic imides
FR2681325B1 (en) * 1991-09-16 1993-12-17 Fabre Medicament Pierre DERIVATIVES OF AMINOMETHYL-4 PIPERIDINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
DE4135474A1 (en) * 1991-10-28 1993-04-29 Bayer Ag 2-AMINOMETHYL-chromans
FR2702211B1 (en) * 1993-03-04 1995-06-02 Pf Medicament New derivatives of 2-phenoxyethylamine, their preparation and their therapeutic use.

Also Published As

Publication number Publication date
FR2769629A1 (en) 1999-04-16

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CD Change of name or company name
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Effective date: 20130628