FR2685918B1 - Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. - Google Patents
Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.Info
- Publication number
- FR2685918B1 FR2685918B1 FR9200138A FR9200138A FR2685918B1 FR 2685918 B1 FR2685918 B1 FR 2685918B1 FR 9200138 A FR9200138 A FR 9200138A FR 9200138 A FR9200138 A FR 9200138A FR 2685918 B1 FR2685918 B1 FR 2685918B1
- Authority
- FR
- France
- Prior art keywords
- processes
- preparation
- pharmaceutical compositions
- compositions containing
- pct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000003835 adenosine derivatives Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (26)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9200138A FR2685918B1 (fr) | 1992-01-08 | 1992-01-08 | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. |
| US07/832,576 US5229505A (en) | 1992-01-08 | 1992-02-07 | N6 -[3-(1-substituted)indolylethyl] adenosine 5'-carboxamides and their pharmaceutical compositions |
| NZ246904A NZ246904A (en) | 1992-01-08 | 1992-12-29 | 6-(indol-3-ylalkylamino)substituted adenosine derivatives, their preparation and pharmaceutical compositions |
| HU9402040A HU221304B1 (en) | 1992-01-08 | 1992-12-29 | New adenosine derivatives, medicaments containing the same and process for producing them |
| AU34550/93A AU661894B2 (en) | 1992-01-08 | 1992-12-29 | New adenosine derivatives, preparation methods and pharmaceutical compositions containing them |
| RU94039545A RU2129560C1 (ru) | 1992-01-08 | 1992-12-29 | Производные аденозина, способ их получения, фармацевтическая композиция и способ ее получения |
| AT93914481T ATE153342T1 (de) | 1992-01-08 | 1992-12-29 | Adenosinderivate, verfahren zu deren herstellung und pharmazeutische mittel |
| JP51218093A JP3224542B2 (ja) | 1992-01-08 | 1992-12-29 | 新規なアデノシン誘導体，その製造方法およびそれを含有する医薬組成物 |
| DE69219901T DE69219901T2 (de) | 1992-01-08 | 1992-12-29 | Adenosinderivate, Verfahren zu deren Herstellung und pharmazeutische Mittel |
| ES93914481T ES2105285T3 (es) | 1992-01-08 | 1992-12-29 | Nuevos derivados de la adenosina, sus procedimientos de preparacion, composiciones farmaceuticas que los contienen. |
| KR1019940702365A KR100232672B1 (ko) | 1992-01-08 | 1992-12-29 | 신규한 아데노신 유도체, 아데노신 유도체의 제조방법 및 이를 포함하는 약제 조성물 |
| SK818-94A SK282205B6 (sk) | 1992-01-08 | 1992-12-29 | Adenozínové deriváty, spôsob ich prípravy a farmaceutický prostriedok obsahujúci tieto zlúčeniny |
| CA002127472A CA2127472C (en) | 1992-01-08 | 1992-12-29 | New adenosine derivatives, preparation methods and pharmaceutical compositions containing them |
| CZ19941643A CZ289047B6 (cs) | 1992-01-08 | 1992-12-29 | Adenosinové deriváty, způsob jejich přípravy, a farmaceutický prostředek obsahující tyto sloučeniny |
| EP93914481A EP0623138B1 (fr) | 1992-01-08 | 1992-12-29 | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant |
| PCT/FR1992/001241 WO1993014102A1 (fr) | 1992-01-08 | 1992-12-29 | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant |
| DK93914481.2T DK0623138T3 (da) | 1992-01-08 | 1992-12-29 | Nye adenosinderivater, fremgangsmåder til deres fremstilling og farmaceutiske præparater med indhold deraf |
| GEAP19922541A GEP19981357B (en) | 1992-01-08 | 1992-12-29 | New Adenozine Derivatives, Prepatation Methods and Pharmaceutical Composit¬i¬ons Containing Them |
| US08/256,081 US5480983A (en) | 1992-01-08 | 1992-12-29 | Adenosine derivatives, preparation methods and pharmaceutical compositions containing them |
| UA94005387A UA44221C2 (uk) | 1992-01-08 | 1992-12-29 | Похідні аденозину, спосіб їх отримання , фармацевтична композиція на їх основі, спосіб отримання фармацевтичної композиції |
| TW082100078A TW254945B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1992-01-08 | 1993-01-07 | |
| FI943222A FI106205B (fi) | 1992-01-08 | 1994-07-06 | Menetelmä terapeuttisesti aktiivisten adenosiinijohdannaisten valmistamiseksi |
| EE9400381A EE03087B1 (et) | 1992-01-08 | 1994-11-22 | Adenosiini derivaadid, nende valmistamise meetodid ja neid sisaldavad ravimvormid |
| MD95-0111A MD502G2 (ro) | 1992-01-08 | 1994-12-30 | Derivaţi noi ai adenozinei, procedee de preparare a lor, compoziţii farmaceutice ce le conţin |
| LVP-97-128A LV11899B (lv) | 1992-01-08 | 1997-06-25 | Jauni adenozīna atvasinājumi, to iegūšanas paņēmiens |
| GR970402030T GR3024386T3 (en) | 1992-01-08 | 1997-08-07 | New adenosine derivatives, preparation methods and pharmaceutical compositions containing them. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9200138A FR2685918B1 (fr) | 1992-01-08 | 1992-01-08 | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2685918A1 FR2685918A1 (fr) | 1993-07-09 |
| FR2685918B1 true FR2685918B1 (fr) | 1995-06-23 |
Family
ID=9425478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR9200138A Expired - Lifetime FR2685918B1 (fr) | 1992-01-08 | 1992-01-08 | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. |
Country Status (25)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2685918B1 (fr) * | 1992-01-08 | 1995-06-23 | Union Pharma Scient Appl | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. |
| WO1995018817A1 (fr) * | 1994-01-07 | 1995-07-13 | Laboratoires Upsa | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant |
| FR2714907B1 (fr) * | 1994-01-07 | 1996-03-29 | Union Pharma Scient Appl | Nouveaux dérivés de l'Adénosine, leurs procédés de préparation, compositions pharmaceutiques les contenant. |
| TW528755B (en) | 1996-12-24 | 2003-04-21 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
| FR2772271B1 (fr) * | 1997-12-11 | 2000-09-01 | Union Pharma Scient Appl | Nouvelle association pharmaceutique a activite analgesique |
| YU44900A (sh) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola |
| KR20010071591A (ko) | 1998-06-23 | 2001-07-28 | 그레이엄 브레레톤, 레슬리 에드워즈 | 2-(퓨린-9-일)-테트라히드로푸란-3,4-디올 유도체 |
| JP2002173427A (ja) * | 1998-09-01 | 2002-06-21 | Yamasa Shoyu Co Ltd | 眼疾患治療用医薬組成物 |
| DE19924818A1 (de) * | 1999-05-29 | 2000-11-30 | Bayer Ag | Substituierte Phenylcyclohexancarbonsäureamide |
| AU770395B2 (en) * | 1999-11-17 | 2004-02-19 | Boston Scientific Limited | Microfabricated devices for the delivery of molecules into a carrier fluid |
| WO2002020539A1 (fr) * | 2000-09-08 | 2002-03-14 | Toa Eiyo Ltd. | Derives d'adenosine et leur utilisation |
| EP1352910A1 (en) * | 2002-04-10 | 2003-10-15 | Grünenthal GmbH | New analogs of nitrobenzylthioinosine |
| AR049384A1 (es) | 2004-05-24 | 2006-07-26 | Glaxo Group Ltd | Derivados de purina |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE788958A (fr) * | 1971-09-18 | 1973-03-19 | Schering Ag | Derives d'adenosine et leur procede de preparation |
| US4167565A (en) * | 1976-11-08 | 1979-09-11 | Abbott Laboratories | Adenosine-5'-carboxamides and method of use |
| US5310731A (en) * | 1984-06-28 | 1994-05-10 | Whitby Research, Inc. | N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents |
| US4755594A (en) * | 1986-01-31 | 1988-07-05 | Warner-Lambert Company | N6 -substituted adenosines |
| JPH0696534B2 (ja) * | 1986-04-25 | 1994-11-30 | ヘキストジヤパン株式会社 | 抗痴呆剤 |
| WO1988003148A2 (en) * | 1986-10-31 | 1988-05-05 | Warner-Lambert Company | Heteroaromatic derivatives of adenoside |
| AU8276187A (en) * | 1986-10-31 | 1988-05-25 | Warner-Lambert Company | Selected n6-substituted adenosines having selective a2 binding activity |
| IL84414A0 (en) * | 1986-11-14 | 1988-04-29 | Ciba Geigy Ag | N9-cyclopentyl-substituted adenine derivatives |
| SU1661367A1 (ru) * | 1988-11-01 | 1991-07-07 | Всесоюзный научно-исследовательский институт по креплению скважин и буровым растворам | Способ гидрофобизации тампонажных материалов |
| CA2092305C (en) * | 1990-09-25 | 2003-02-11 | Alfred P. Spada | Compounds having antihypertensive and anti-ischemic properties |
| FR2685918B1 (fr) * | 1992-01-08 | 1995-06-23 | Union Pharma Scient Appl | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. |
-
1992
- 1992-01-08 FR FR9200138A patent/FR2685918B1/fr not_active Expired - Lifetime
- 1992-02-07 US US07/832,576 patent/US5229505A/en not_active Expired - Lifetime
- 1992-12-29 RU RU94039545A patent/RU2129560C1/ru active
- 1992-12-29 NZ NZ246904A patent/NZ246904A/en not_active IP Right Cessation
- 1992-12-29 AU AU34550/93A patent/AU661894B2/en not_active Expired
- 1992-12-29 UA UA94005387A patent/UA44221C2/uk unknown
- 1992-12-29 SK SK818-94A patent/SK282205B6/sk not_active IP Right Cessation
- 1992-12-29 ES ES93914481T patent/ES2105285T3/es not_active Expired - Lifetime
- 1992-12-29 AT AT93914481T patent/ATE153342T1/de active
- 1992-12-29 EP EP93914481A patent/EP0623138B1/fr not_active Expired - Lifetime
- 1992-12-29 US US08/256,081 patent/US5480983A/en not_active Expired - Lifetime
- 1992-12-29 HU HU9402040A patent/HU221304B1/hu unknown
- 1992-12-29 KR KR1019940702365A patent/KR100232672B1/ko not_active Expired - Lifetime
- 1992-12-29 DE DE69219901T patent/DE69219901T2/de not_active Expired - Lifetime
- 1992-12-29 DK DK93914481.2T patent/DK0623138T3/da active
- 1992-12-29 JP JP51218093A patent/JP3224542B2/ja not_active Expired - Lifetime
- 1992-12-29 CA CA002127472A patent/CA2127472C/en not_active Expired - Lifetime
- 1992-12-29 WO PCT/FR1992/001241 patent/WO1993014102A1/fr active IP Right Grant
- 1992-12-29 CZ CZ19941643A patent/CZ289047B6/cs not_active IP Right Cessation
- 1992-12-29 GE GEAP19922541A patent/GEP19981357B/en unknown
-
1993
- 1993-01-07 TW TW082100078A patent/TW254945B/zh not_active IP Right Cessation
-
1994
- 1994-07-06 FI FI943222A patent/FI106205B/fi not_active IP Right Cessation
- 1994-11-22 EE EE9400381A patent/EE03087B1/xx unknown
- 1994-12-30 MD MD95-0111A patent/MD502G2/ro active IP Right Grant
-
1997
- 1997-06-25 LV LVP-97-128A patent/LV11899B/lv unknown
- 1997-08-07 GR GR970402030T patent/GR3024386T3/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FR2685918B1 (fr) | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. | |
| FR2686084B1 (fr) | Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques. | |
| ATE286500T1 (de) | 1,2,3,4-tetrahydroisochinolin-derivate | |
| PT87552A (pt) | Process for the preparation of novel tetrazole intermediates toantihypertensive compounds | |
| ATE219765T1 (de) | Indolderivate als cgmp-pde inhibitoren | |
| BG103518A (en) | 2-(purin-9-yl)tetrahydrofuran-3,4-diol derivatives | |
| UA41297C2 (uk) | Похідні індолу, фармацевтична композиція і спосіб лікування | |
| MY123354A (en) | 4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives | |
| FR2714378B1 (fr) | Dérivés de l'indol-2-one substitués en 3 par un groupe azoté, leur préparation, les compositions pharmaceutiques en contenant. | |
| FR2743562B1 (fr) | Derives de n-(arylsulfonyl) aminoacides, leur preparation, les compositions pharmaceutiques en contenant | |
| BG103947A (en) | Derivatives of 9-oxymerythromycin | |
| KR890700125A (ko) | 신규 벤즈이미다졸 유도체, 그 제조방법 및 이 화합물을 함유하는 제약 조성물 | |
| FR2361901A1 (fr) | Derives de substitution de nucleotides et medicament contenant ces substances | |
| FR2681784B1 (fr) | Composition dermatologique et/ou cosmetologique contenant des retinouides et utilisation de nouveaux retinouides. | |
| BG100069A (bg) | Амидинови производни,съдържащи хетероциклични групи,получаване и приложението им | |
| FR2613365B1 (fr) | Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent | |
| TR200000153T2 (tr) | İl-5 inhibite eden 6-azaurasil türevleri. | |
| FR2687678B1 (fr) | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. | |
| MX9709451A (es) | Derivados de benzisoxazol e indazol como agentes antipsicoticos. | |
| FR2699176B1 (fr) | Nouveaux composés bicycliques de pyrimidine, leur procédé de préparation et les compositions pharmaceutiques les renfermant. | |
| TR200402070T4 (tr) | Siklobüten-dion türevleri ve bunların damar sertliği tedavisinde kullanımı | |
| ATE199641T1 (de) | Terpenderivate (sarcodictyine) als antikrebsmittel | |
| BR9604907B1 (pt) | derivados de nucleosidios homocarbociclico de pirimidinodiona substituìda antiviral e composição contendo derivados de nucleosidios homocarbociclico de pirimidinodiona substituìda antiviral com princìpios ativos. | |
| AP9801235A0 (en) | Erythromycin derivatives. |