FR2663225B1 - Nouvelle utilisation du modafinil. - Google Patents

Nouvelle utilisation du modafinil.

Info

Publication number
FR2663225B1
FR2663225B1 FR9007442A FR9007442A FR2663225B1 FR 2663225 B1 FR2663225 B1 FR 2663225B1 FR 9007442 A FR9007442 A FR 9007442A FR 9007442 A FR9007442 A FR 9007442A FR 2663225 B1 FR2663225 B1 FR 2663225B1
Authority
FR
France
Prior art keywords
modafinil
new use
new
medicament
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9007442A
Other languages
English (en)
French (fr)
Other versions
FR2663225A1 (fr
Inventor
Louis Lafon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Priority to FR9007442A priority Critical patent/FR2663225B1/fr
Priority to DE69112717T priority patent/DE69112717T2/de
Priority to DK91401563.1T priority patent/DK0462004T3/da
Priority to AT91401563T priority patent/ATE127341T1/de
Priority to EP91401563A priority patent/EP0462004B1/fr
Priority to HU911968A priority patent/HU215590B/hu
Priority to US07/713,376 priority patent/US5180745A/en
Priority to KR1019910009712A priority patent/KR100190454B1/ko
Priority to JP3143267A priority patent/JP2531868B2/ja
Priority to AU78436/91A priority patent/AU655769B2/en
Priority to TW080105041A priority patent/TW206916B/zh
Publication of FR2663225A1 publication Critical patent/FR2663225A1/fr
Application granted granted Critical
Publication of FR2663225B1 publication Critical patent/FR2663225B1/fr
Priority to HK98106619A priority patent/HK1007415A1/xx
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Networks Using Active Elements (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Steroid Compounds (AREA)
FR9007442A 1990-06-14 1990-06-14 Nouvelle utilisation du modafinil. Expired - Lifetime FR2663225B1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR9007442A FR2663225B1 (fr) 1990-06-14 1990-06-14 Nouvelle utilisation du modafinil.
DK91401563.1T DK0462004T3 (da) 1990-06-14 1991-06-12 Hidtil ukendt anvendelse af modafinil
AT91401563T ATE127341T1 (de) 1990-06-14 1991-06-12 Neue verwendung von modafinil.
EP91401563A EP0462004B1 (fr) 1990-06-14 1991-06-12 Nouvelle utilisation du modafinil
DE69112717T DE69112717T2 (de) 1990-06-14 1991-06-12 Neue Verwendung von Modafinil.
US07/713,376 US5180745A (en) 1990-06-14 1991-06-13 Method for providing a neuroprotective effect
HU911968A HU215590B (hu) 1990-06-14 1991-06-13 Eljárás modafiniltartalmú a nigro-neurostriatalis terület dopaminerg útjára, kolinerg-, noradrenerg- és 5-OH triptamin-neuranokra kifejtett hatás alapján a központi idegrendszer degeneratív megbetegedéseinek kezelésére szolgáló gyógyászati készítmény ..
KR1019910009712A KR100190454B1 (ko) 1990-06-14 1991-06-13 모다피닐의 용도
JP3143267A JP2531868B2 (ja) 1990-06-14 1991-06-14 モダフィニルの新規使用
AU78436/91A AU655769B2 (en) 1990-06-14 1991-06-14 Novel use of modafinil
TW080105041A TW206916B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1990-06-14 1991-06-28
HK98106619A HK1007415A1 (en) 1990-06-14 1998-06-25 New use of modafinil

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9007442A FR2663225B1 (fr) 1990-06-14 1990-06-14 Nouvelle utilisation du modafinil.

Publications (2)

Publication Number Publication Date
FR2663225A1 FR2663225A1 (fr) 1991-12-20
FR2663225B1 true FR2663225B1 (fr) 1994-11-04

Family

ID=9397614

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9007442A Expired - Lifetime FR2663225B1 (fr) 1990-06-14 1990-06-14 Nouvelle utilisation du modafinil.

Country Status (12)

Country Link
US (1) US5180745A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0462004B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP2531868B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100190454B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE127341T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU655769B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69112717T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0462004T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2663225B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK1007415A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU215590B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW206916B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR950010400B1 (ko) * 1990-08-16 1995-09-16 삼성전자주식회사 김치냉장고의 발효 및 저장제어방법
FR2684875B1 (fr) * 1991-12-13 1995-05-24 Lafon Labor Utilisation du modafinil pour la fabrication d'un medicament ayant un effet anti-ischemique.
US5281607B1 (en) * 1992-10-08 1998-05-19 Univ New York Method of using alpha 2-antagonists for the treatment of neurodegenerative diseases
FR2697162B1 (fr) * 1992-10-23 1995-01-13 Lafon Labor Utilisation du modafinil pour la fabrication d'un médicament pour le traitement de l'incontinence urinaire et des troubles sphinctériens urétro vésicaux.
FR2706767B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1993-06-22 1995-09-08 Lafon Labor
FR2708201B1 (fr) * 1993-06-30 1995-10-20 Lafon Labor Utilisation de dérivés d'acétamide pour la fabrication de médicaments.
US5618845A (en) 1994-10-06 1997-04-08 Cephalon, Inc. Acetamide derivative having defined particle size
KR980010274A (ko) * 1996-07-23 1998-04-30 오상수 열전소자를 이용한 식품저장고
US6346548B1 (en) * 1999-08-16 2002-02-12 Cephalon, Inc. Compositions including modafinil for treatment of attention deficit hyperactivity disorder and multiple sclerosis fatigue
US6455588B1 (en) 1999-08-20 2002-09-24 Cephalon, Inc. Compositions including modafinil for treatment of eating disorders and for appetite stimulation
KR100350444B1 (ko) * 2000-02-22 2002-08-28 만도공조 주식회사 복합형 김치저장고
US6492396B2 (en) * 2000-05-16 2002-12-10 Cephalon, Inc. Substituted thioacetamides
US6489363B2 (en) 2000-10-11 2002-12-03 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
US6919378B2 (en) * 2000-10-11 2005-07-19 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
MXPA03003152A (es) * 2000-10-11 2005-07-29 Cephalon Inc Composiciones que contienen compuestos de modafinilo.
US7704975B2 (en) * 2000-12-19 2010-04-27 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US7141555B2 (en) 2000-12-19 2006-11-28 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
KR100911779B1 (ko) * 2001-05-25 2009-08-12 세파론, 인코포레이티드 모다피닐을 포함하는 고형 제약 제제
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
US20040048931A1 (en) 2002-07-12 2004-03-11 Craig Heacock Modafinil pharmaceutical compositions
US6992219B2 (en) * 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
US20040116532A1 (en) * 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
IL153098A0 (en) * 2002-11-26 2003-06-24 Chemagis Ltd Pharmaceutical compositions containing modafinil
FR2849029B1 (fr) * 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
CA2511992A1 (en) * 2003-02-24 2004-09-10 Mallinckrodt Inc. Process for preparing benzhydrylthioacetamide
US20040253308A1 (en) * 2003-04-29 2004-12-16 Barr Laboratories, Inc. Surface-treated modafinil particles
AR045423A1 (es) * 2003-05-13 2005-10-26 Cephalon Inc Combinaciones de analiticos y antidepresivos
US7368591B2 (en) 2003-09-19 2008-05-06 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
US7423176B2 (en) * 2004-04-13 2008-09-09 Cephalon, Inc. Bicyclic aromatic sulfinyl derivatives
US7119214B2 (en) * 2004-04-13 2006-10-10 Cephalon France Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives
US7449481B2 (en) * 2004-04-13 2008-11-11 Cephalon, Inc. Thio-substituted biaryl-methanesulfinyl derivatives
US7297817B2 (en) * 2004-04-13 2007-11-20 Cephalon France Thio-substituted arylmethanesulfinyl derivatives
EP1586560A1 (en) * 2004-04-13 2005-10-19 Cephalon, Inc. Thio-substituted arylmethanesulfinyl derivatives
US7314875B2 (en) * 2004-04-13 2008-01-01 Cephalon, Inc. Tricyclic aromatic and bis-phenyl sulfinyl derivatives
US20060024370A1 (en) * 2004-07-29 2006-02-02 Cephalon France Modafinil oral lyophilizate
US20080181966A1 (en) * 2006-10-18 2008-07-31 Cephalon, Inc. Modafinil pharmaceutical compositions
WO2008077127A2 (en) * 2006-12-19 2008-06-26 Lavin Thomas N Use of modafinil to treat restless leg syndrome
US20090325999A1 (en) * 2008-06-27 2009-12-31 Jie Du Personalized pharmaceutical kits, packaging and compositions for the treatment of allergic conditions
EP2238973A1 (en) 2009-04-07 2010-10-13 Cephalon France Lyophilized preparations of proteasome inhibitors
CN111437297A (zh) 2013-08-30 2020-07-24 绿十字生命健康有限公司 用于预防及治疗癌因性疲乏的组合物及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1520812A (en) * 1975-10-02 1978-08-09 Lafon Labor Benzhydrylsulphinyl derivatives
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
FR2593809B1 (fr) * 1986-01-31 1988-07-22 Lafon Labor Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique

Also Published As

Publication number Publication date
DK0462004T3 (da) 1995-10-16
JPH04230214A (ja) 1992-08-19
AU7843691A (en) 1991-12-19
EP0462004A3 (en) 1992-01-22
TW206916B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-06-01
HU215590B (hu) 1999-01-28
HUT57984A (en) 1992-01-28
KR920000315A (ko) 1992-01-29
AU655769B2 (en) 1995-01-12
DE69112717T2 (de) 1996-04-11
US5180745A (en) 1993-01-19
HU911968D0 (en) 1991-12-30
EP0462004B1 (fr) 1995-09-06
HK1007415A1 (en) 1999-04-09
FR2663225A1 (fr) 1991-12-20
EP0462004A2 (fr) 1991-12-18
ATE127341T1 (de) 1995-09-15
KR100190454B1 (ko) 1999-06-01
JP2531868B2 (ja) 1996-09-04
DE69112717D1 (de) 1995-10-12

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