FR2600205A1 - Apparatus for measuring and irradiating cavities - Google Patents
Apparatus for measuring and irradiating cavities Download PDFInfo
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- FR2600205A1 FR2600205A1 FR8707471A FR8707471A FR2600205A1 FR 2600205 A1 FR2600205 A1 FR 2600205A1 FR 8707471 A FR8707471 A FR 8707471A FR 8707471 A FR8707471 A FR 8707471A FR 2600205 A1 FR2600205 A1 FR 2600205A1
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- catheter
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- dispersing agent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1027—Making of balloon catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00064—Constructional details of the endoscope body
- A61B1/00071—Insertion part of the endoscope body
- A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
- A61B1/00082—Balloons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1011—Multiple balloon catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22051—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
- A61B2017/22054—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation with two balloons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22051—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
- A61B2017/22057—Optical properties
- A61B2017/22059—Optical properties transparent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22051—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
- A61B2017/22062—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation to be filled with liquid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
- A61B2018/2255—Optical elements at the distal end of probe tips
- A61B2018/2261—Optical elements at the distal end of probe tips with scattering, diffusion or dispersion of light
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1052—Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1088—Balloon catheters with special features or adapted for special applications having special surface characteristics depending on material properties or added substances, e.g. for reducing friction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
- A61N5/0603—Apparatus for use inside the body for treatment of body cavities
- A61N2005/061—Bladder and/or urethra
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
Abstract
Description
"Appareil pour mesurer et irradier des cavités"
L'invention concerne un appareil de mesure et d'irradiation de cavités dans lequel est introduit un agent dispersant pour le rayonnement qui doit être excité, ce rayonnement ainsi qu'un rayonnement- de mesure pouvant être accouplé ou désaccouplé par l'intermédiaire d'un cathéter, la source de rayonnement ainsi que le détecteur de mesure étant montés sur le cathéter. Un appareil de ce genre est déJà connu par le DE-OS 33 25 365."Apparatus for measuring and irradiating cavities"
The invention relates to a device for measuring and irradiating cavities into which a dispersing agent is introduced for the radiation which is to be excited, this radiation as well as a measuring radiation which can be coupled or uncoupled by means of a catheter, the radiation source and the measurement detector being mounted on the catheter. A device of this kind is already known from DE-OS 33 25 365.
Dans les tumeurs à croissance multiloculaire, par exemple les carcinomes de la vessie, à côté de foyers tumoraux que l'on peut déceler de manière macroscopique, il existe aussi très fréquemment des régions tumorales très petites, microscopiques, réparties sur toute la paroi intérieure de la vessie. Etant donné que celles-ci ne peuvent actuellement pas être détectées dans les opérations thérapeutiques courantes (voir par exemple "Der Urologe", édition B 21, DG, 3ème fascicule, juin 1982), dans environ 50 % des cas, il apparalt, par exemple, dans un carcinome de la vessie ce qu'on appelle une récidive de la tumeur récidivante, dans les 15 mois qui suivent le premier traitement. In tumors with multilocular growth, for example carcinomas of the bladder, alongside tumor foci which can be detected macroscopically, there are also very frequently very small, microscopic tumor regions distributed over the entire inner wall of the bladder. Since these cannot currently be detected in current therapeutic operations (see for example "Der Urologe", edition B 21, DG, 3rd booklet, June 1982), in about 50% of cases, it appears, by for example, in a bladder carcinoma what is called a recurrence of the recurrent tumor, within 15 months of the first treatment.
Les procédés thérapeutiques utilisés jusqu'ici dans le traitement des carcinomes de la vessie comprennent la résection transuréthrale, la résection partielle de la vessie, la coagulation de la tumeur par un courant électrique ou un rayonnement laser (Nd YAG, Laser à l'argon). Des installations cytostatiques locales dans la vessie ont pu réduire les quotas de récidive des tumeurs à croissance superficielle dans une proportion maximum de30 %. Ni l'hyperthermie locale qui n'en est encore qu'au stade expérimental, ni l'utilisation de rayons ionisants n'ont toutefois apporté des améliorations sensibles. The therapeutic methods hitherto used in the treatment of carcinomas of the bladder include transurethral resection, partial resection of the bladder, coagulation of the tumor by an electric current or laser radiation (Nd YAG, Argon laser) . Local cytostatic facilities in the bladder could reduce recurrence quotas for surface growth tumors by up to 30%. Neither the local hyperthermia which is still only in the experimental stage, nor the use of ionizing rays have brought significant improvements, however.
Il est connu (voir par exemple 3. of Urology, vol. 115 Février, pages 150-151) que l'on peut rendre sensibles à la lumière, c'est-à-dire photo-sensibiliser sélectivement des tumeurs qui se développent en étant dispersées dans la paroi intérieure d'organes creux en administrant des substances chimiques appropriées telles que les dérivés de l'hématoporphyrine (HpD), l'hématoporphyrine, la porphyrine, la tétracyline, l'orangé d'acridine,
L'irradiation avec une lumière appropriée, dans le cas de l'HpD par exemple une lumière (Laser) rouge, entrai#ne des réactions photochimiques dans les tissus photosensibilisés qui finalement provoquent une destruction du tissu tumoral. Le tissu normal non-sensibilisé n'est en revanche pas endommagé par une irradiation lumineuse à faible énergie.It is known (see for example 3. of Urology, vol. 115 February, pages 150-151) that one can make sensitive to light, that is to say selectively photo-sensitize tumors which develop in being dispersed in the inner wall of hollow organs by administering appropriate chemicals such as hematoporphyrin derivatives (HpD), hematoporphyrin, porphyrin, tetracyline, acridine orange,
Irradiation with an appropriate light, in the case of HpD for example a red (laser) light, causes photochemical reactions in the photosensitized tissues which ultimately cause destruction of the tumor tissue. Normal non-sensitized tissue, on the other hand, is not damaged by low-energy light irradiation.
On se heurte également à des problèmes dans le domaine technique, en particulier dans la construction des automobiles, pour rechercher explorer et/ou irradier pour les sceller des cavités qui ne sont à peu près pas, ou ne sont que difficilement accessibles. Les memes problèmes se présentent dans le domaine de la sauvegarde du patrimoine pour éviter une poursuite de la dégradation de cavités existant dans des monuments ou des objets précieux du point de vue archéologique ou historique, ou pour sceller ces cavités pour des raisons de stabilité. Problems are also encountered in the technical field, in particular in the construction of automobiles, in seeking to explore and / or irradiate in order to seal them cavities which are almost not, or are only difficult to access. The same problems arise in the field of safeguarding the heritage in order to avoid further deterioration of cavities existing in monuments or objects precious from an archaeological or historical point of view, or to seal these cavities for reasons of stability.
Dans la thérapeutique photodynamique des tumeurs à croissance multiloculaire photosensibilisées, il est apparu - les memes remarques sont également valables pour les autres domaines d'utilisation technique - qu'une irradiation uniforme des cavités est absolument nécessaire pour obtenir des résultats efficaces. In photodynamic therapy of photosensitized multilocular growing tumors, it has appeared - the same remarks also apply to other areas of technical use - that uniform irradiation of the cavities is absolutely necessary to obtain effective results.
(s.P.A. Marinissen et W. M. Star, localisation de la porphyrine et traitement des tumeurs, pages 133 à 148, 1984 Alan R. Liss. Inc.). Cette condition ne peut être satisfaite avec l'appareillage connu jusqu'ici car une introduction reproductible et localement contrôlable du corps de cathéter dans les cavités est pratiquement exclue. (s.P.A. Marinissen and W. M. Star, localization of porphyrin and treatment of tumors, pages 133 to 148, 1984 Alan R. Liss. Inc.). This condition cannot be satisfied with the apparatus known hitherto since a reproducible and locally controllable introduction of the catheter body into the cavities is practically excluded.
La présente invention a pour objet de modifier cet appareillage pour lui donner une configuration telle qu'il permette une mise en place et une fixation sûre du cathéter dans la cavité, et ainsi une mesure directe de l'intensité de l'irradiation. The object of the present invention is to modify this apparatus to give it a configuration such that it allows secure positioning and fixing of the catheter in the cavity, and thus a direct measurement of the intensity of the irradiation.
A cet effet l'appareil selon l'invention est caractérisé en ce que sont fixés sur le corls du cathéter, au moins deux ballon-nets, optiquement transparents, entourant le corps du cathéter et disposés à une certaine distance l'un de l'autre, ces ballonnets pouvant etre gonflés avec l'agent dispersant, de façon telle qu'ils viennent s'appliquer sur des parties de la paroi de la cavité. For this purpose the apparatus according to the invention is characterized in that are fixed to the corls of the catheter, at least two balloons-nets, optically transparent, surrounding the body of the catheter and arranged at a certain distance from one other, these balloons can be inflated with the dispersing agent, so that they are applied to parts of the wall of the cavity.
D'autres améliorations et modes de réalisation avantageux ressortiront de la description ci-après. Other improvements and advantageous embodiments will emerge from the description below.
En liaison avec l'agent de dispersion on peut obtenir de façon sûre un éclairement uniforme de cavités, en particulier d'organes creux, et il est possible de surveiller cet éclairement. On remplit de préférence avec l'agent de dispersion deux ballonnets de fixation en une matière optiquement transparente éventuellement aussi dispersante, au moyen d'un cathéter possédant plusieurs foyers lumineux. Les espaces intermédiaires de la cavité qui ne sont pas atteints par les ballonnets sont ensuite remplis par d'autres canaux du cathéter (éventuellement des canaux de balayage), avec un agent dispersant compatible avec le corps, et le cas échéant balayés pendant l'irradiation. Des conducteurs lumineux par l'irradiation peuvent etre intégrés dans des canaux séparés.La courte partie du cathéter qui se trouve entre les ballonnets est avantageusement plus rigide que les autres parties du cathéter, pour éviter d'une façon sûre que cette partie du cathéter s'applique sur la paroi de la cavité. La mise en place des détecteurs isotropes ou des diodes en des points qui sont voisins de zones de la paroi de la cavité qui sont critiques au point de vue de la technique d'irradiation, permet de doser exactement l'irradiation penda#nt toute la durée de cette opération. L'intensité lumineuse enregistrée dans les détecteurs isotropes est transmise à un instrument de mesure extérieur par des conducteurs lumineux flexibles, intégrés dans la paroi du cathéter ou par des canaux conducteurs séparés. In connection with the dispersing agent, uniform illumination of cavities, in particular of hollow organs, can be surely obtained, and it is possible to monitor this illumination. Two fixing balloons are preferably filled with the dispersing agent in an optically transparent material, possibly also dispersing, by means of a catheter having several light sources. The intermediate spaces of the cavity which are not reached by the balloons are then filled by other catheter channels (possibly scanning channels), with a dispersing agent compatible with the body, and if necessary scanned during irradiation. . Light conductors by irradiation can be integrated in separate channels. The short part of the catheter which is located between the balloons is advantageously more rigid than the other parts of the catheter, to avoid in a safe way that this part of the catheter s applied to the wall of the cavity. The placement of isotropic detectors or diodes at points which are close to areas of the wall of the cavity which are critical from the point of view of the irradiation technique, makes it possible to exactly dose the irradiation during the entire period. duration of this operation. The light intensity recorded in the isotropic detectors is transmitted to an external measuring instrument by flexible light conductors, integrated in the wall of the catheter or by separate conducting channels.
Le cathéter de mesure et d'irradiation suivant l'invention permet, pour la première fois, de mettre en place, d'une façon sure, douce et précise un conducteur lumineux au centre d'une cavité pour l'éclairer d'une façon homogène, entre autres en utilisant un agent dispersant. Contraitement aux procédés qui peuvent constituer une alternative d'appareils extérieurs de contrôle, supplémentaires, de la position de l'extrémité du conducteur lumineux dans l'organe creux, on peut tenir compte des différences de configuration d'organes en faisant appel à la détection isotrope dans le choix des paramètres d'irradiation. Des cavités tubulaires peuvent être éclairées d'une façon homogène dans des sections bien définies en rendant étanches des aires déterminées au moyen des ballonnets (volume de remplissage variable). The measuring and irradiation catheter according to the invention makes it possible, for the first time, to set up, in a safe, gentle and precise manner, a light conductor in the center of a cavity to illuminate it in a way homogeneous, inter alia by using a dispersing agent. Contrary to the methods which can constitute an alternative of external, additional control devices, of the position of the end of the light conductor in the hollow organ, one can take into account the differences in configuration of organs by calling on detection isotropic in the choice of irradiation parameters. Tubular cavities can be uniformly illuminated in well-defined sections by sealing certain areas by means of balloons (variable filling volume).
L'invention sera décrite plus en détail ci-après, avec référence à deux exemples de réalisation illustrés dans les figures 1 à 3. The invention will be described in more detail below, with reference to two exemplary embodiments illustrated in Figures 1 to 3.
On se propose suivant les figures 1 et 2 qui sont des coupes schématiques, d'obtenir un positionnement et une fixation sures d'un conducteur de rayon laser dans un organe creux 2 (par exemple la vessie), pour y réaliser un éclairement uniforme. Celui-ci est nécessaire pour la thérapie photodynamique intégrale des tumeurs photosensibilisées. Il est toutefois absolument nécessaire d'empêcher un contact de la paroi avec l'extrémité 3 de la fibre rayonnante et l'importante luminance locale qui y est liée. Pour la surveillance de l'irradiation que l'on a avantage à ne pas effectuer avec l'oeil, mode de traitement délicat, risques d'éblouissement, protection de l'oeil contre le rayonnement (laser) !), et pour la détection, il est prévu des détecteurs isotropes 4, qui sont disposés sur des points choisis du corps du cathéter 5 et des ballonnets 10, 11. It is proposed according to Figures 1 and 2 which are schematic sections, to obtain a secure positioning and fixing of a laser beam conductor in a hollow member 2 (for example the bladder), to achieve uniform illumination. This is necessary for the integral photodynamic therapy of photosensitized tumors. It is however absolutely necessary to prevent contact of the wall with the end 3 of the radiating fiber and the significant local luminance which is linked to it. For the monitoring of the irradiation which it is advantageous not to carry out with the eye, delicate treatment mode, risks of dazzling, protection of the eye against radiation (laser)!), And for detection , isotropic detectors 4 are provided, which are arranged at selected points on the body of the catheter 5 and the balloons 10, 11.
Le corps du cathéter 5 est constitué essentiellement par un tube allongé, souple, dont la pointe 25 peut être pourvue d'un agent contrastant pour les rayons X. Le conducteur 1 de la lumière laser est mis en place au centre du tube. Les quatre conducteurs de mesure 6 (fibres optiques en verre), allant des détecteurs 4 (des diodes par exemple) à la tête de mesures ou vice
versa et deux canaux 8, 9 allant aux deux#bal1onets 10, 11, y sont aussi logés. Les positions de ces derniers qui sont avantageusement diamétralement opposées dans la paroi du corps du cathéter 5 sont représentées sur la figure 2 qui est une coupe de la figure 1 suivant A.A. Le corps 5 du cathéter renferme également l'arrivée et le départ, 12, 13 de l'agent dispersant qui doit aller dans la zone 18 de l'organe creux 2.Le faisceau de fibres optiques 1, 3 est fixé, par rapport à la paroi du cathéter 5, par le plan de séparation en deux parties 14, ce plan 14 séparant l'arrivée et le départ 12, 13 de l'agent de dispersion.The body of the catheter 5 consists essentially of an elongated, flexible tube, the tip 25 of which can be provided with a contrasting agent for X-rays. The conductor 1 of the laser light is placed in the center of the tube. The four measurement conductors 6 (glass optical fibers), ranging from detectors 4 (for example diodes) to the measurement head or vice
versa and two channels 8, 9 going to the two # bal1onets 10, 11, are also housed there. The positions of the latter which are advantageously diametrically opposite in the wall of the body of the catheter 5 are shown in FIG. 2 which is a section of FIG. 1 along AA The body 5 of the catheter also contains the arrival and departure, 12, 13 of the dispersing agent which must go into the zone 18 of the hollow member 2. The bundle of optical fibers 1, 3 is fixed, relative to the wall of the catheter 5, by the plane of separation into two parts 14, this plane 14 separating the arrival and departure 12, 13 of the dispersing agent.
Les ballonnets 10 et 11 (fig. 1), sont fixés coaxialement autour du cathéter et peuvent être gonflés avec l'agent dispersant 26 par des ouvertures 15, 16, de façon telle que leurs parois extérieures s'appliquent sur la surface intérieure de l'organe creux 2. L'enveloppe des ballonnets est souple et optiquement transparente. The balloons 10 and 11 (fig. 1) are fixed coaxially around the catheter and can be inflated with the dispersing agent 26 through openings 15, 16, so that their outer walls are applied to the inner surface of the 'hollow organ 2. The envelope of the balloons is flexible and optically transparent.
Ceux qui peuvent, quand ils sont vides, être introduits avec le cathéter 5 dans l'organe creux 2. La partie 17 du cathéter 5, qui se trouve entre les deux ballonnets, est plus rigide que les autres parties, afin qu'il ne puisse se produire aucune modification de la distance qui sépare les deux ballonnets 10, 11 par exemple par courbure.Those which, when empty, can be inserted with the catheter 5 into the hollow organ 2. The part 17 of the catheter 5, which is located between the two balloons, is more rigid than the other parts, so that it does not may occur any change in the distance between the two balloons 10, 11 for example by curvature.
Pour effectuer des mesures ou pour des raisons thérapeutiques, l'espace intermédiaire 18 entre les ballonnets 10, 11 est lui aussi rempli d'agent dispersant 26, et ce, par les orifices 19, 20 d'entrée et de sortie dans l'arrivée et le départ 12, 13 placés sur le cathéter, de préférence dans la zone 17. Les ballonnets 10, 11, pouvant être gonflés au moyen des injecteurs 21, 22, de la tête du cathéter, s'appliquent sur la paroi intérieure de l'organe creux 2, de façon à permettre un centrage du corps du cathéter 5, et de la pointe 3 du conducteur de lumière. Les détecteurs 4 sont disposés aussi bien sur les ballonnets 10, 11, que sur le corps du cathéter lui-même. La tête du cathéter 23 peut être pourvue d'une arrivée d'eau (refroidissement) 24. To carry out measurements or for therapeutic reasons, the intermediate space 18 between the balloons 10, 11 is also filled with dispersing agent 26, and this, through the orifices 19, 20 of inlet and outlet in the inlet and the outlet 12, 13 placed on the catheter, preferably in the area 17. The balloons 10, 11, which can be inflated by means of the injectors 21, 22, of the head of the catheter, are applied to the inner wall of the 'hollow organ 2, so as to allow centering of the body of the catheter 5, and the tip 3 of the light conductor. The detectors 4 are arranged both on the balloons 10, 11, and on the body of the catheter itself. The head of the catheter 23 can be provided with a water supply (cooling) 24.
La figure 3 est une coupe d'une partie d'un organe creux 27 cylindrique, ou une partie d'un oesophage, d'un intestin ou d'un vaisseau sanguin. Le corps du cathéter 5 contenant la fibre optique 1, et les deux ballonnets~10, 11, limite une zone allongée 18 contenant de l'agent dispersant 26. Figure 3 is a section through a portion of a hollow cylindrical member 27, or a portion of an esophagus, intestine or blood vessel. The body of the catheter 5 containing the optical fiber 1, and the two balloons ~ 10, 11, limits an elongated zone 18 containing dispersing agent 26.
La partie rigide 17 du corps du cathéter 5 peut, en particulier quand l'organe creux 27 est lui-même courbé ou enroulé, être fixée au moyen d'autres ballonnets intermédiaires qui ne sont pas représentés. Les ballonnets extérieurs 10, 11 peuvent également servir à assurer l'étanchéité par rapport à des milieux extérieurs. Les détecteurs, qui ne sont pas représentés sur cette figure, peuvent être intégrés dans le corps du cathéter comme dans l'exemple de réalisation des figures 1 et 2, ou être introduits séparément. En tant que détecteurs 4, on peut faire appel par exemple à des détecteurs à fibres de verre, ou à des composants semi-conducteurs. Au lieu de la fibre optique 1, on peut aussi intégrer dans le corps du cathéter 5 d'autres sources d'irradiation lumineuse (laser-semi-conducteur), lampes à incandescence, LED), et/ou des sources radio-actives, (par exemple pour l'examen de la paroi). Quand on soumet exclusivement la zone 18 à la lumière, une disposition utilisant des ballonnets 10, 11 non-transparents et/ou un remplissage non transparent des ballonnets convient également. Il est en principe possible de gonfler les ballonnets 10, 11 avec des milieux différents. The rigid part 17 of the body of the catheter 5 can, in particular when the hollow member 27 is itself curved or wound, be fixed by means of other intermediate balloons which are not shown. The external balloons 10, 11 can also be used to seal against external environments. The detectors, which are not shown in this figure, can be integrated into the body of the catheter as in the embodiment of Figures 1 and 2, or be introduced separately. As detectors 4, it is possible, for example, to use glass fiber detectors, or semiconductor components. Instead of the optical fiber 1, it is also possible to integrate into the body of the catheter 5 other sources of light irradiation (laser-semiconductor), incandescent lamps, LED), and / or radioactive sources, (for example for the examination of the wall). When the area 18 is exclusively subjected to light, a provision using non-transparent balloons 10, 11 and / or a non-transparent filling of the balloons is also suitable. It is in principle possible to inflate the balloons 10, 11 with different media.
Claims (5)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863620123 DE3620123A1 (en) | 1986-06-14 | 1986-06-14 | MEASURING AND RADIATION DEVICE FOR CAVITIES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2600205A1 true FR2600205A1 (en) | 1987-12-18 |
| FR2600205B1 FR2600205B1 (en) | 1995-03-03 |
Family
ID=6303052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8707471A Granted FR2600205A1 (en) | 1986-06-14 | 1987-05-27 | Apparatus for measuring and irradiating cavities |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPH0751156B2 (en) |
| DE (1) | DE3620123A1 (en) |
| FR (1) | FR2600205A1 (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2644699A1 (en) * | 1989-03-25 | 1990-09-28 | Strahlen Umweltforsch Gmbh | METHOD AND DEVICE FOR IRRADIATION OF CAVITIES FROM THE INTERIOR |
| EP0428875A2 (en) * | 1989-10-24 | 1991-05-29 | Zewa Ag | Apparatus to treat diseases of the walls of body orifices or cavities |
| US5320604A (en) * | 1991-04-24 | 1994-06-14 | Baxter International Inc. | Low-profile single-lumen dual-balloon catheter with integrated guide wire for embolectomy dilatation/occlusion and delivery of treatment fluid |
| US5454788A (en) * | 1991-04-24 | 1995-10-03 | Baxter International Inc. | Exchangeable integrated-wire balloon catheter |
| FR2767703A1 (en) * | 1997-09-04 | 1999-03-05 | Medlight Sa | DEVICE FOR THE IRRADIATION OF INTERNAL CAVITIES OF THE ORGANISM |
| USRE37315E1 (en) | 1991-11-11 | 2001-08-07 | Medical Enterprises Ltd. | Radiating device for hyperthermia |
| WO2002000128A2 (en) * | 2000-06-23 | 2002-01-03 | Cryocath Technologies, Inc. | Cryotreatment device and method |
| WO2002053218A2 (en) * | 2000-12-28 | 2002-07-11 | The Regents Of The University Of California | An implantable photo applicator for long term fractionated photodynamic and radiation therapy and method of using the same |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2729275B2 (en) * | 1988-10-05 | 1998-03-18 | 則雄 大工園 | Heating device by laser light |
| EP0965363B1 (en) | 1994-06-24 | 2002-02-13 | Schneider (Europe) GmbH | Medical appliance for the treatment of a portion of body vessel by ionizing radiation |
| US5899882A (en) | 1994-10-27 | 1999-05-04 | Novoste Corporation | Catheter apparatus for radiation treatment of a desired area in the vascular system of a patient |
| US5683345A (en) * | 1994-10-27 | 1997-11-04 | Novoste Corporation | Method and apparatus for treating a desired area in the vascular system of a patient |
| ATE192346T1 (en) * | 1995-06-22 | 2000-05-15 | Schneider Europ Gmbh | MEDICINAL DEVICE FOR THE TREATMENT OF A PART OF A BODY VESSEL USING IONIZATION RADIATION |
| US6273850B1 (en) | 1997-10-29 | 2001-08-14 | Medtronic Ave, Inc. | Device for positioning a radiation source at a stenosis treatment site |
| DE102005007574B3 (en) | 2005-02-18 | 2006-08-31 | Siemens Ag | catheter device |
| DE102005008955A1 (en) * | 2005-02-27 | 2006-09-07 | Lothar Sellin | Medical implant for treating restenosis by generating reactive species in vivo in conjunction with laser light, comprises photosensitizer on its surface |
| DE102006003181A1 (en) * | 2006-01-23 | 2007-07-05 | Siemens Ag | Centering catheter has two sections whereby area between two sections consists of material transparent for light assigned with optical coherence tomography or photo-dynamic therapy and second section is expandable by pressure application |
| US9326785B2 (en) * | 2011-05-12 | 2016-05-03 | Microline Surgical, Inc. | Connector for a laparoscopic surgical system |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2848484A1 (en) * | 1977-11-08 | 1979-05-10 | Olympus Optical Co | ENDOSCOPE |
| DE2829516A1 (en) * | 1978-07-05 | 1980-01-17 | Messerschmitt Boelkow Blohm | Monitor for medical laser coagulator - detects changes in thermal radiation from irradiated tissue for conversion to temperature values |
| WO1983003188A1 (en) * | 1982-03-11 | 1983-09-29 | Laserscope Inc | Endoscopic device |
| FR2577410A1 (en) * | 1985-02-20 | 1986-08-22 | Gilles Karcher | Laser endoscope |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3235974A1 (en) * | 1981-11-24 | 1983-06-01 | Volkmar Dipl.-Ing. Merkel (FH), 8520 Erlangen | DEVICE FOR REMOVAL OR FOR THE EXPANSION OF CONSTRAINTS IN BODY LIQUID LEADING VESSELS |
| DE3323365C2 (en) * | 1982-09-04 | 1994-10-20 | Gsf Forschungszentrum Umwelt | Method and device for illuminating cavities |
-
1986
- 1986-06-14 DE DE19863620123 patent/DE3620123A1/en not_active Ceased
-
1987
- 1987-05-27 FR FR8707471A patent/FR2600205A1/en active Granted
- 1987-06-15 JP JP62147185A patent/JPH0751156B2/en not_active Expired - Lifetime
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2848484A1 (en) * | 1977-11-08 | 1979-05-10 | Olympus Optical Co | ENDOSCOPE |
| DE2829516A1 (en) * | 1978-07-05 | 1980-01-17 | Messerschmitt Boelkow Blohm | Monitor for medical laser coagulator - detects changes in thermal radiation from irradiated tissue for conversion to temperature values |
| WO1983003188A1 (en) * | 1982-03-11 | 1983-09-29 | Laserscope Inc | Endoscopic device |
| FR2577410A1 (en) * | 1985-02-20 | 1986-08-22 | Gilles Karcher | Laser endoscope |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2644699A1 (en) * | 1989-03-25 | 1990-09-28 | Strahlen Umweltforsch Gmbh | METHOD AND DEVICE FOR IRRADIATION OF CAVITIES FROM THE INTERIOR |
| EP0428875A2 (en) * | 1989-10-24 | 1991-05-29 | Zewa Ag | Apparatus to treat diseases of the walls of body orifices or cavities |
| EP0428875A3 (en) * | 1989-10-24 | 1991-09-18 | Zewa Ag | Apparatus to treat diseases of the walls of body orifices or cavities |
| CH679274A5 (en) * | 1989-10-24 | 1992-01-31 | Zewa Ag | |
| US5320604A (en) * | 1991-04-24 | 1994-06-14 | Baxter International Inc. | Low-profile single-lumen dual-balloon catheter with integrated guide wire for embolectomy dilatation/occlusion and delivery of treatment fluid |
| US5454788A (en) * | 1991-04-24 | 1995-10-03 | Baxter International Inc. | Exchangeable integrated-wire balloon catheter |
| USRE37315E1 (en) | 1991-11-11 | 2001-08-07 | Medical Enterprises Ltd. | Radiating device for hyperthermia |
| FR2767703A1 (en) * | 1997-09-04 | 1999-03-05 | Medlight Sa | DEVICE FOR THE IRRADIATION OF INTERNAL CAVITIES OF THE ORGANISM |
| WO1999011322A1 (en) * | 1997-09-04 | 1999-03-11 | Medlight S.A. | Device for irradiating internal cavities of the body |
| US6364874B1 (en) | 1997-09-04 | 2002-04-02 | Medlight S.A. | Device for irradiating internal cavities of the body |
| WO2002000128A2 (en) * | 2000-06-23 | 2002-01-03 | Cryocath Technologies, Inc. | Cryotreatment device and method |
| WO2002000128A3 (en) * | 2000-06-23 | 2002-06-06 | Cryocath Technologies Inc | Cryotreatment device and method |
| US6595988B2 (en) | 2000-06-23 | 2003-07-22 | Cryocath Technologies Inc. | Cryotreatment device and method |
| WO2002053218A2 (en) * | 2000-12-28 | 2002-07-11 | The Regents Of The University Of California | An implantable photo applicator for long term fractionated photodynamic and radiation therapy and method of using the same |
| WO2002053218A3 (en) * | 2000-12-28 | 2003-01-16 | Univ California | An implantable photo applicator for long term fractionated photodynamic and radiation therapy and method of using the same |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2600205B1 (en) | 1995-03-03 |
| JPH0751156B2 (en) | 1995-06-05 |
| JPS63260577A (en) | 1988-10-27 |
| DE3620123A1 (en) | 1987-12-17 |
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| ST | Notification of lapse |