FR2571374B1 - Nouveaux derives de 5-fluoro-2'-desoxyuridine et leurs sels, leur procede de preparation, et agents antitumoraux les contenant - Google Patents

Nouveaux derives de 5-fluoro-2'-desoxyuridine et leurs sels, leur procede de preparation, et agents antitumoraux les contenant

Info

Publication number
FR2571374B1
FR2571374B1 FR8514854A FR8514854A FR2571374B1 FR 2571374 B1 FR2571374 B1 FR 2571374B1 FR 8514854 A FR8514854 A FR 8514854A FR 8514854 A FR8514854 A FR 8514854A FR 2571374 B1 FR2571374 B1 FR 2571374B1
Authority
FR
France
Prior art keywords
desoxyuridine
fluoro
derivatives
salts
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8514854A
Other languages
English (en)
French (fr)
Other versions
FR2571374A1 (fr
Inventor
Takako Hori
Isao Myokan
Shinji Miyabara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP21052584A external-priority patent/JPS6191196A/ja
Priority claimed from JP919285A external-priority patent/JPH0655755B2/ja
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of FR2571374A1 publication Critical patent/FR2571374A1/fr
Application granted granted Critical
Publication of FR2571374B1 publication Critical patent/FR2571374B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FR8514854A 1984-10-09 1985-10-08 Nouveaux derives de 5-fluoro-2'-desoxyuridine et leurs sels, leur procede de preparation, et agents antitumoraux les contenant Expired FR2571374B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21052584A JPS6191196A (ja) 1984-10-09 1984-10-09 新規な５―フルオロ―２´―デオキシウリジン―５´―ホスフェート誘導体およびその塩並びにそれらを含有する抗腫瘍剤
JP919285A JPH0655755B2 (ja) 1985-01-23 1985-01-23 新規な５−フルオロ−２′−デオキシウリジン−３′−ホスフエ−ト誘導体およびその塩

Publications (2)

Publication Number Publication Date
FR2571374A1 FR2571374A1 (fr) 1986-04-11
FR2571374B1 true FR2571374B1 (fr) 1988-09-09

Family

ID=26343875

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8514854A Expired FR2571374B1 (fr) 1984-10-09 1985-10-08 Nouveaux derives de 5-fluoro-2'-desoxyuridine et leurs sels, leur procede de preparation, et agents antitumoraux les contenant

Country Status (9)

Country Link
US (2) US4684631A (forum.php)
BE (1) BE903389A (forum.php)
CH (1) CH670091A5 (forum.php)
DE (1) DE3535766A1 (forum.php)
DK (1) DK166830B1 (forum.php)
FR (1) FR2571374B1 (forum.php)
GB (1) GB2166740B (forum.php)
NL (1) NL8502739A (forum.php)
SE (1) SE466151B (forum.php)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684631A (en) * 1984-10-09 1987-08-04 Toyama Chemical Co., Ltd. Novel 5-fluoro-2-deoxyuridine derivatives and salts thereof, process for producing the same, and antitumor agents containing the same
JPS61189215A (ja) * 1985-02-18 1986-08-22 Teijin Ltd ５−フルオロ−２′−デオキシウリジンエステル類の油状医薬組成物
AU610344B2 (en) * 1988-02-29 1991-05-16 Taiho Pharmaceutical Co., Ltd. 2'-deoxy-5-fluorouridine derivatives
GB2260319B (en) 1991-10-07 1995-12-06 Norsk Hydro As Acyl derivatives of nucleosides and nucleoside analogues having anti-viral activity
GB9307043D0 (en) * 1993-04-05 1993-05-26 Norsk Hydro As Chemical compounds
WO2007130783A2 (en) 2006-05-03 2007-11-15 Chimerix, Inc. Metabolically stable alkoxyalkyl esters of antiviral or antiproliferative phosphonates, nucleoside phosphonates and nucleoside phosphates
US20130018006A1 (en) * 2011-07-14 2013-01-17 Stephen King Atheroscleroclastic Bioceutical Formulations

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR767195A (fr) * 1934-01-17 1934-07-12 Batteuse centrifuge
JPS457056Y1 (forum.php) * 1968-07-31 1970-04-07
BE767195A (en) * 1970-05-30 1971-11-16 Soc D Etudes Prod Chimique Betaine inosinate, uridylate and cytidylate, hepatoprotective agents
JPS4886869A (forum.php) * 1972-02-23 1973-11-15
JPS57128699A (en) * 1981-02-03 1982-08-10 Tokyo Kinzoku Kogyo Kk 5-fluorouracil derivative and its medical composition
DE3263939D1 (en) * 1981-12-09 1985-07-04 Teijin Ltd 5-fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof
JPS5993096A (ja) * 1982-11-19 1984-05-29 Teijin Ltd ５−フルオロ−２′−デオキシウリジン誘導体及びその製造法
US4684631A (en) * 1984-10-09 1987-08-04 Toyama Chemical Co., Ltd. Novel 5-fluoro-2-deoxyuridine derivatives and salts thereof, process for producing the same, and antitumor agents containing the same

Also Published As

Publication number Publication date
DK457985D0 (da) 1985-10-08
GB2166740A (en) 1986-05-14
US4740503A (en) 1988-04-26
BE903389A (fr) 1986-04-08
GB8524309D0 (en) 1985-11-06
DK457985A (da) 1986-04-10
GB2166740B (en) 1987-11-18
SE8504657L (sv) 1986-04-10
DK166830B1 (da) 1993-07-19
SE466151B (sv) 1992-01-07
SE8504657D0 (sv) 1985-10-08
NL8502739A (nl) 1986-05-01
FR2571374A1 (fr) 1986-04-11
DE3535766A1 (de) 1986-04-17
CH670091A5 (forum.php) 1989-05-12
US4684631A (en) 1987-08-04

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Legal Events

Date Code Title Description
ST Notification of lapse