FR2518093A2 - Nouveaux derives de l'hydroxyphenyl tetrahydropyridine, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant - Google Patents
Nouveaux derives de l'hydroxyphenyl tetrahydropyridine, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant Download PDFInfo
- Publication number
- FR2518093A2 FR2518093A2 FR8123275A FR8123275A FR2518093A2 FR 2518093 A2 FR2518093 A2 FR 2518093A2 FR 8123275 A FR8123275 A FR 8123275A FR 8123275 A FR8123275 A FR 8123275A FR 2518093 A2 FR2518093 A2 FR 2518093A2
- Authority
- FR
- France
- Prior art keywords
- sep
- formula
- tetrahydropyridin
- tetrahydropyridine
- phenol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical compound [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 208000022821 personality disease Diseases 0.000 description 1
- LIGACIXOYTUXAW-UHFFFAOYSA-N phenacyl bromide Chemical compound BrCC(=O)C1=CC=CC=C1 LIGACIXOYTUXAW-UHFFFAOYSA-N 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000009991 scouring Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000009518 sodium iodide Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 238000000859 sublimation Methods 0.000 description 1
- 230000008022 sublimation Effects 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 235000011044 succinic acid Nutrition 0.000 description 1
- 150000003444 succinic acids Chemical class 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8123275A FR2518093A2 (fr) | 1980-12-15 | 1981-12-14 | Nouveaux derives de l'hydroxyphenyl tetrahydropyridine, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8026540A FR2496099A1 (fr) | 1980-12-15 | 1980-12-15 | Nouveaux derives de l'hydroxyphenyl tetrahydropyridine, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant |
| FR8123275A FR2518093A2 (fr) | 1980-12-15 | 1981-12-14 | Nouveaux derives de l'hydroxyphenyl tetrahydropyridine, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2518093A2 true FR2518093A2 (fr) | 1983-06-17 |
| FR2518093B2 FR2518093B2 (enrdf_load_stackoverflow) | 1984-02-17 |
Family
ID=26222121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8123275A Granted FR2518093A2 (fr) | 1980-12-15 | 1981-12-14 | Nouveaux derives de l'hydroxyphenyl tetrahydropyridine, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2518093A2 (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2703354A1 (fr) * | 1993-03-31 | 1994-10-07 | Lafon Labor | Dérivés de 1, 2, 5, 6-tétrahydropyridine, leur procédé de préparation et leurs applications en thérapeutique. |
| FR2721513A1 (fr) * | 1994-06-23 | 1995-12-29 | Lafon Labor | Utilisation de dérivés de 1,2,5,6-tétrahydropyridine pour la fabrication de médicaments à effet sédatif. |
| FR2721514A1 (fr) * | 1994-06-23 | 1995-12-29 | Lafon Labor | Compositions thérapeutiques comprenant des 3-phényl-3-hydroxypipéridines. |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2498431A (en) * | 1945-06-13 | 1950-02-21 | Hoffmann La Roche | 2-and 4-homocyclyl substituted piperidines |
| FR2034448A1 (en) * | 1968-02-23 | 1970-12-11 | Beecham Group Ltd | Benzoxazocine derivs cns active |
| FR2310762A1 (fr) * | 1975-05-16 | 1976-12-10 | Roussel Uclaf | Nouveaux derives n-substitues de la phenyl piperidine et leurs sels, procede de preparation et application a titre de medicaments |
| US4081450A (en) * | 1974-09-06 | 1978-03-28 | Eli Lilly And Company | 1,3,4-Trisubstituted-4-arylpiperidines and their preparation |
-
1981
- 1981-12-14 FR FR8123275A patent/FR2518093A2/fr active Granted
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2498431A (en) * | 1945-06-13 | 1950-02-21 | Hoffmann La Roche | 2-and 4-homocyclyl substituted piperidines |
| FR2034448A1 (en) * | 1968-02-23 | 1970-12-11 | Beecham Group Ltd | Benzoxazocine derivs cns active |
| US4081450A (en) * | 1974-09-06 | 1978-03-28 | Eli Lilly And Company | 1,3,4-Trisubstituted-4-arylpiperidines and their preparation |
| FR2310762A1 (fr) * | 1975-05-16 | 1976-12-10 | Roussel Uclaf | Nouveaux derives n-substitues de la phenyl piperidine et leurs sels, procede de preparation et application a titre de medicaments |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2703354A1 (fr) * | 1993-03-31 | 1994-10-07 | Lafon Labor | Dérivés de 1, 2, 5, 6-tétrahydropyridine, leur procédé de préparation et leurs applications en thérapeutique. |
| WO1994022827A1 (fr) * | 1993-03-31 | 1994-10-13 | Laboratoire L. Lafon | Derives de 3-phenyl-1,2,5,6-tetrahydropyridine comme sedatifs |
| US5439920A (en) * | 1993-03-31 | 1995-08-08 | Laboratoire L. Lafon | 1,2,5,6-tetrahydropyridine derivative, process for preparing it and its applications in therapy |
| FR2721513A1 (fr) * | 1994-06-23 | 1995-12-29 | Lafon Labor | Utilisation de dérivés de 1,2,5,6-tétrahydropyridine pour la fabrication de médicaments à effet sédatif. |
| FR2721514A1 (fr) * | 1994-06-23 | 1995-12-29 | Lafon Labor | Compositions thérapeutiques comprenant des 3-phényl-3-hydroxypipéridines. |
| WO1996000064A1 (fr) * | 1994-06-23 | 1996-01-04 | Laboratoire L. Lafon | Compositions therapeutiques comprenant des 3-phenyl-3-hydroxypiperidines |
| WO1996000063A1 (fr) * | 1994-06-23 | 1996-01-04 | Laboratoire L. Lafon | Utilisation de derives de 1,2,5,6-tetrahydropyridine pour la fabrication de medicaments a effet sedatif |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2518093B2 (enrdf_load_stackoverflow) | 1984-02-17 |
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