FR2502627A1 - Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent - Google Patents

Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent Download PDF

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Publication number
FR2502627A1
FR2502627A1 FR8101930A FR8101930A FR2502627A1 FR 2502627 A1 FR2502627 A1 FR 2502627A1 FR 8101930 A FR8101930 A FR 8101930A FR 8101930 A FR8101930 A FR 8101930A FR 2502627 A1 FR2502627 A1 FR 2502627A1
Authority
FR
France
Prior art keywords
erythromycin
oral
salt
preparation
animals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR8101930A
Other languages
English (en)
French (fr)
Inventor
Jacques Gonella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Refarmed SA
Original Assignee
Refarmed SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Refarmed SA filed Critical Refarmed SA
Priority to FR8101930A priority Critical patent/FR2502627A1/fr
Priority to EP82200131A priority patent/EP0060573B1/en
Priority to EP82200130A priority patent/EP0057489B1/en
Priority to DE8282200130T priority patent/DE3274243D1/de
Priority to DE8282200131T priority patent/DE3262069D1/de
Priority to DE8484116047T priority patent/DE3279709D1/de
Priority to AT82200131T priority patent/ATE11546T1/de
Priority to EP84116047A priority patent/EP0174395B1/en
Priority to AT84116047T priority patent/ATE43347T1/de
Priority to AT82200130T priority patent/ATE23538T1/de
Priority to IT8219410A priority patent/IT1210849B/it
Priority to ES510030A priority patent/ES8305001A1/es
Priority to US06/344,961 priority patent/US4393053A/en
Priority to JP57015441A priority patent/JPS57176996A/ja
Priority to JP57015442A priority patent/JPS57176997A/ja
Publication of FR2502627A1 publication Critical patent/FR2502627A1/fr
Priority to IT8421319A priority patent/IT1227789B/it
Priority to JP59155725A priority patent/JPS60132999A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
FR8101930A 1981-02-02 1981-02-02 Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent Withdrawn FR2502627A1 (fr)

Priority Applications (17)

Application Number Priority Date Filing Date Title
FR8101930A FR2502627A1 (fr) 1981-02-02 1981-02-02 Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent
AT82200130T ATE23538T1 (de) 1981-02-02 1982-02-01 Erythromycin-derivate, welche schwefel enthalten, mit einer therapeutischen wirkung, verfahren zu ihrer herstellung und die sie enthaltenden pharmazeutischen zubereitungen.
EP82200130A EP0057489B1 (en) 1981-02-02 1982-02-01 Thiolic derivatives of erythromycin having therapeutic activity, process for their preparation and pharmaceutical compositions containing them
DE8282200130T DE3274243D1 (en) 1981-02-02 1982-02-01 Thiolic derivatives of erythromycin having therapeutic activity, process for their preparation and pharmaceutical compositions containing them
DE8282200131T DE3262069D1 (en) 1981-02-02 1982-02-01 Thiolic derivatives of erythromycin having therapeutic activity, process for their preparation and pharmaceutical compositions containing them
DE8484116047T DE3279709D1 (en) 1981-02-02 1982-02-01 Salts of erythromycin with mercapto-succinic acid having therapeutic activity, process for their preparation and pharmaceutical compositions containing them
AT82200131T ATE11546T1 (de) 1981-02-02 1982-02-01 Schwefel enthaltende erythromycinderivate mit therapeutischer wirkung, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen.
EP84116047A EP0174395B1 (en) 1981-02-02 1982-02-01 Salts of erythromycin with mercapto-succinic acid having therapeutic activity, process for their preparation and pharmaceutical compositions containing them
AT84116047T ATE43347T1 (de) 1981-02-02 1982-02-01 Erythromycin-salze mit mercapto-bernsteinsaeure mit therapeutischer wirkung, verfahren zu ihrer herstellung und die sie enthaltenden pharmazeutischen zusammensetzungen.
EP82200131A EP0060573B1 (en) 1981-02-02 1982-02-01 Thiolic derivatives of erythromycin having therapeutic activity, process for their preparation and pharmaceutical compositions containing them
IT8219410A IT1210849B (it) 1981-02-02 1982-02-02 Derivati tiolici dell'eritromicina ad attivita' terapeutica, relativo procedimento di preparazione e composizioni farmaceutiche che licontengono.
ES510030A ES8305001A1 (es) 1981-02-02 1982-02-02 "procedimiento de preparacion de derivados tiolicos de erotromicina y del ester propionico de eritromicina".
US06/344,961 US4393053A (en) 1981-02-02 1982-02-02 Thiolic derivatives or erythromycin having therapeutic activity and pharmaceutical compositions containing them
JP57015441A JPS57176996A (en) 1981-02-02 1982-02-02 Thiol derivative of erythromycin, manufacture and composition
JP57015442A JPS57176997A (en) 1981-02-02 1982-02-02 Thiol derivative of erythromycin, manufacture and composition
IT8421319A IT1227789B (it) 1981-02-02 1984-06-08 Derivati tiolici dell'eritromicina ad attivita' terapeutica, relativo procedimento di preparazione e composizioni farmaceutiche che li contengono.
JP59155725A JPS60132999A (ja) 1981-02-02 1984-07-27 エリスロマイシンのチオ−ル誘導体、その製造方法並びにそれを含有する組成物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8101930A FR2502627A1 (fr) 1981-02-02 1981-02-02 Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent

Publications (1)

Publication Number Publication Date
FR2502627A1 true FR2502627A1 (fr) 1982-10-01

Family

ID=9254718

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8101930A Withdrawn FR2502627A1 (fr) 1981-02-02 1981-02-02 Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent

Country Status (7)

Country Link
US (1) US4393053A (en:Method)
EP (3) EP0057489B1 (en:Method)
JP (3) JPS57176997A (en:Method)
AT (2) ATE43347T1 (en:Method)
DE (2) DE3274243D1 (en:Method)
ES (1) ES8305001A1 (en:Method)
FR (1) FR2502627A1 (en:Method)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549057A1 (fr) * 1983-05-30 1985-01-18 Pavese Ist Biochim Derives a activite therapeutique de la s-carboxymethylcysteine, leur procede de preparation et compositions pharmaceutiques qui en renferment

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1163108B (it) * 1983-02-16 1987-04-08 Corvi Camillo Spa Sale di eritromicina dell'acido benzoico-o-carboniltiazolidina,procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono
US5333914A (en) * 1992-01-17 1994-08-02 Toyoda Gosei Co., Ltd. Hose device
WO1996019489A1 (en) * 1994-12-19 1996-06-27 Russinsky Limited Compounds
WO1998005674A1 (en) * 1996-08-07 1998-02-12 Russinsky Limited Process for the production of salts of erythromycin, roxithromycin, clarithromycin and azithromycin
ATE399541T1 (de) * 1998-08-18 2008-07-15 Univ California Epidermale wachstumsfaktor rezeptor antagonisten zur behandlung stark vermehrter schleimsekretion in der lunge
AU760884B2 (en) 1998-10-20 2003-05-22 Russinsky Limited Derivatives of erythromycin, clarithromycin, roxithromycin or azithromycin with antibiotic and mucolytic activity
US7923047B2 (en) 2006-06-30 2011-04-12 Conagra Foods Rdm, Inc. Seasoning and method for seasoning a food product while reducing dietary sodium intake

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2653899A (en) * 1952-04-14 1953-09-29 Lilly Co Eli Erythromycin, its salts, and method of preparation
US2743268A (en) * 1952-07-12 1956-04-24 Lilly Co Eli Erythromycin-penicillin
US2830982A (en) * 1955-06-03 1958-04-15 Abbott Lab Water-soluble salt of erythromycin
FR1465403A (fr) * 1965-07-02 1967-01-13 Roussel Uclaf Nouveau sel d'érythromycine et procédé de préparation
US3558594A (en) * 1968-09-04 1971-01-26 Abbott Lab Erythromycin aliphatic sulfate
GB1250045A (en) * 1969-01-15 1971-10-20 Pierrel Spa A new water soluble derivative of erythromycin
US3843787A (en) * 1969-01-15 1974-10-22 Pierrel Spa Water soluble derivative of erythromycin
US3847896A (en) * 1973-04-09 1974-11-12 Upjohn Co Erythromycin-2-thiol esters and process
DK139522C (da) * 1975-04-07 1979-08-20 Thomae Gmbh Dr K Analogifremgangsmaade til fremstilling af 9-iminoalkylamino-erythromyciner eller syreadditionssalte deraf
US4261982A (en) * 1977-11-09 1981-04-14 The Procter & Gamble Company Therapeutic composition
CA1121825A (en) * 1978-04-11 1982-04-13 Franco Bolasco 2-(2-thenoylthio)-propionylglycine: method for its preparation and pharmaceutical formulations containing said compound
US4264765A (en) * 1980-02-20 1981-04-28 Abbott Laboratories Salts of erythromycin A esters
IT1148890B (it) * 1980-07-22 1986-12-03 Neopharmed Spa Derivato della teonil tiopropionil glicina e procedimento per la sua preparazione

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549057A1 (fr) * 1983-05-30 1985-01-18 Pavese Ist Biochim Derives a activite therapeutique de la s-carboxymethylcysteine, leur procede de preparation et compositions pharmaceutiques qui en renferment

Also Published As

Publication number Publication date
EP0060573A1 (en) 1982-09-22
JPS60132999A (ja) 1985-07-16
JPH0216320B2 (en:Method) 1990-04-16
EP0057489B1 (en) 1986-11-12
ES510030A0 (es) 1983-04-01
US4393053A (en) 1983-07-12
JPS57176997A (en) 1982-10-30
JPS57176996A (en) 1982-10-30
EP0060573B1 (en) 1985-01-30
EP0057489A1 (en) 1982-08-11
ES8305001A1 (es) 1983-04-01
JPH0317840B2 (en:Method) 1991-03-11
DE3262069D1 (en) 1985-03-14
JPH0216758B2 (en:Method) 1990-04-18
DE3274243D1 (en) 1987-01-02
EP0174395A3 (en) 1986-08-27
ATE11546T1 (de) 1985-02-15
EP0174395B1 (en) 1989-05-24
EP0174395A2 (en) 1986-03-19
ATE43347T1 (de) 1989-06-15

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