FR2481280A1 - Procede de preparation de derives de 2-guanidinothiazole, nouveaux produits ainsi obtenus et leur utilisation comme agents contre les ulceres d'estomac - Google Patents
Procede de preparation de derives de 2-guanidinothiazole, nouveaux produits ainsi obtenus et leur utilisation comme agents contre les ulceres d'estomac Download PDFInfo
- Publication number
- FR2481280A1 FR2481280A1 FR8108468A FR8108468A FR2481280A1 FR 2481280 A1 FR2481280 A1 FR 2481280A1 FR 8108468 A FR8108468 A FR 8108468A FR 8108468 A FR8108468 A FR 8108468A FR 2481280 A1 FR2481280 A1 FR 2481280A1
- Authority
- FR
- France
- Prior art keywords
- group
- thiazole
- compound according
- ethylthiomethyl
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14494680A | 1980-04-29 | 1980-04-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2481280A1 true FR2481280A1 (fr) | 1981-10-30 |
FR2481280B1 FR2481280B1 (nl) | 1983-10-28 |
Family
ID=22510873
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8108468A Granted FR2481280A1 (fr) | 1980-04-29 | 1981-04-28 | Procede de preparation de derives de 2-guanidinothiazole, nouveaux produits ainsi obtenus et leur utilisation comme agents contre les ulceres d'estomac |
Country Status (16)
Country | Link |
---|---|
JP (1) | JPS574977A (nl) |
AR (1) | AR231538A1 (nl) |
AU (1) | AU540239B2 (nl) |
BE (1) | BE888602A (nl) |
CH (1) | CH646964A5 (nl) |
DE (1) | DE3116890A1 (nl) |
DK (1) | DK188881A (nl) |
ES (1) | ES8206501A1 (nl) |
FR (1) | FR2481280A1 (nl) |
GB (1) | GB2076397B (nl) |
IE (1) | IE51151B1 (nl) |
IL (1) | IL62747A (nl) |
IT (1) | IT1146750B (nl) |
NL (1) | NL8102099A (nl) |
NZ (1) | NZ196923A (nl) |
SE (1) | SE452462B (nl) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4501747A (en) * | 1982-05-10 | 1985-02-26 | Sanofi | Certain amide derivatives of 2-guanidino-thiazoles and compositions containing same |
FR2531705B1 (fr) * | 1982-08-13 | 1986-12-05 | Sanofi Sa | Amidobenzamides, leurs sels, procede pour leur preparation et compositions pharmaceutiques les renfermant |
JPS59104370A (ja) * | 1982-12-03 | 1984-06-16 | Kotobuki Seiyaku Kk | チアゾ−ル誘導体及びその製造方法 |
AU563072B2 (en) * | 1983-04-26 | 1987-06-25 | Shionogi & Co., Ltd. | 2-guanidino-4-hydroxymethylthiazole and derivitives thereof |
US4680300A (en) * | 1985-01-10 | 1987-07-14 | Syntex (U.S.A.) Inc. | Anti-inflammatory guanidines |
US4837316A (en) * | 1985-08-29 | 1989-06-06 | Fujirebio Kabushiki Kaisha | Alkylamide derivatives with H2 -receptor antagonistic and cytoprotective action |
EP0385525B1 (en) * | 1989-03-03 | 1994-04-13 | Akzo Nv | Aminoethylthiazole and aminoethyloxazole derivatives. |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4165378A (en) * | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidine derivatives of imidazoles and thiazoles |
US4165377A (en) * | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidino imidazoles and thiazoles |
EP0003640A2 (en) * | 1978-01-18 | 1979-08-22 | Imperial Chemical Industries Plc | Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them |
EP0010418A1 (en) * | 1978-10-16 | 1980-04-30 | Imperial Chemical Industries Plc | Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them |
EP0010893A1 (en) * | 1978-10-16 | 1980-05-14 | Imperial Chemical Industries Plc | Antisecretory branched-chain heterocyclic guanidine derivatives, processes for their manufacture, intermediates, and pharmaceutical compositions containing said derivatives |
EP0014057A1 (en) * | 1979-01-18 | 1980-08-06 | Imperial Chemical Industries Plc | Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH16099A (en) * | 1979-03-06 | 1983-06-24 | Yamanouchi Pharma Co Ltd | Guanidinothiazole compounds,process for preparing them and medical composition containing them |
GR71929B (nl) * | 1979-11-13 | 1983-08-19 | Ici Ltd | |
JPS5754177A (ja) * | 1980-09-19 | 1982-03-31 | Teikoku Hormone Mfg Co Ltd | Chikanchiazoorujudotai |
JPS57102852A (en) * | 1980-12-19 | 1982-06-26 | Shionogi & Co Ltd | Dicarboxylic acid diamide |
-
1981
- 1981-04-24 NZ NZ196923A patent/NZ196923A/xx unknown
- 1981-04-28 DK DK188881A patent/DK188881A/da not_active Application Discontinuation
- 1981-04-28 ES ES501736A patent/ES8206501A1/es not_active Expired
- 1981-04-28 JP JP6473981A patent/JPS574977A/ja active Granted
- 1981-04-28 SE SE8102683A patent/SE452462B/sv not_active IP Right Cessation
- 1981-04-28 BE BE0/204631A patent/BE888602A/fr not_active IP Right Cessation
- 1981-04-28 DE DE19813116890 patent/DE3116890A1/de not_active Ceased
- 1981-04-28 NL NL8102099A patent/NL8102099A/nl not_active Application Discontinuation
- 1981-04-28 FR FR8108468A patent/FR2481280A1/fr active Granted
- 1981-04-29 IE IE956/81A patent/IE51151B1/en unknown
- 1981-04-29 IT IT67585/81A patent/IT1146750B/it active
- 1981-04-29 AU AU69966/81A patent/AU540239B2/en not_active Ceased
- 1981-04-29 GB GB8113289A patent/GB2076397B/en not_active Expired
- 1981-04-29 CH CH279381A patent/CH646964A5/de not_active IP Right Cessation
- 1981-04-29 IL IL62747A patent/IL62747A/xx unknown
-
1984
- 1984-01-01 AR AR23153884D patent/AR231538A1/es active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4165378A (en) * | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidine derivatives of imidazoles and thiazoles |
US4165377A (en) * | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidino imidazoles and thiazoles |
EP0003640A2 (en) * | 1978-01-18 | 1979-08-22 | Imperial Chemical Industries Plc | Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them |
EP0010418A1 (en) * | 1978-10-16 | 1980-04-30 | Imperial Chemical Industries Plc | Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them |
EP0010893A1 (en) * | 1978-10-16 | 1980-05-14 | Imperial Chemical Industries Plc | Antisecretory branched-chain heterocyclic guanidine derivatives, processes for their manufacture, intermediates, and pharmaceutical compositions containing said derivatives |
EP0014057A1 (en) * | 1979-01-18 | 1980-08-06 | Imperial Chemical Industries Plc | Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them |
Non-Patent Citations (1)
Title |
---|
CA1979 * |
Also Published As
Publication number | Publication date |
---|---|
DE3116890A1 (de) | 1982-03-04 |
NZ196923A (en) | 1983-12-16 |
BE888602A (fr) | 1981-10-28 |
DK188881A (da) | 1981-10-30 |
FR2481280B1 (nl) | 1983-10-28 |
ES501736A0 (es) | 1982-08-16 |
SE8102683L (sv) | 1981-10-30 |
ES8206501A1 (es) | 1982-08-16 |
AR231538A1 (es) | 1984-12-28 |
IT1146750B (it) | 1986-11-19 |
CH646964A5 (de) | 1984-12-28 |
IT8167585A0 (it) | 1981-04-29 |
NL8102099A (nl) | 1981-11-16 |
IE810956L (en) | 1981-10-29 |
GB2076397A (en) | 1981-12-02 |
GB2076397B (en) | 1984-02-08 |
IL62747A0 (en) | 1981-06-29 |
AU540239B2 (en) | 1984-11-08 |
IL62747A (en) | 1984-10-31 |
SE452462B (sv) | 1987-11-30 |
JPH027952B2 (nl) | 1990-02-21 |
IE51151B1 (en) | 1986-10-15 |
AU6996681A (en) | 1981-11-05 |
JPS574977A (en) | 1982-01-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SU888821A3 (ru) | Способ получени 5-(замещенный фенил)-оксазолидинонов или их серусодержащих аналогов | |
CA2050908A1 (en) | Benzimidazole derivatives | |
CN114805314B (zh) | 一种恩赛特韦的合成方法 | |
KR100470887B1 (ko) | 3-아미노-2-머캅토벤조산 유도체 및 이들의 제조방법 | |
US4433154A (en) | Bis(carboxamide) derivatives | |
FR2481280A1 (fr) | Procede de preparation de derives de 2-guanidinothiazole, nouveaux produits ainsi obtenus et leur utilisation comme agents contre les ulceres d'estomac | |
FR2471376A1 (fr) | Derives de thioethylamide, utiles comme bloqueurs d'histamine h2 | |
Maduskuie et al. | Design, synthesis, and structure-activity relationship studies for a new imidazole series of J774 macrophage specific acyl-CoA: cholesterol acyltransferase (ACAT) inhibitors | |
JPH01172378A (ja) | 新規2−グアニジノ−チアゾール化合物、その製造及びファモチジン法の中間体としての使用 | |
PL174526B1 (pl) | Nowe związki pochodne karbazolonu | |
FR2523131A1 (fr) | N-(8a-ergolinyl)-n', n'-diethylurees substituees en 1 et procede d'obtention de ces composes | |
US4157340A (en) | N,N'-[Bis(N-cyanoguanyl)]cystamine derivatives | |
EP0285681A1 (de) | Verfahren zur Herstellung von Nitroethenderivaten | |
FR2534256A1 (nl) | ||
US5030738A (en) | Synthesis of antiulcer compounds | |
US5118813A (en) | Process for the preparation of compounds with antiulcer action | |
US4925944A (en) | Process for the preparation of o-carboxypyridyl- and o-carboxyquinolylimidazolinones | |
US5739382A (en) | Derivatives of 2-aminobenzenesulphonic acid and of 2-aminobenzenesulphonyl chloride, their preparation and their use as synthetic intermediates | |
KR20010005943A (ko) | 0-(3-아미노-2-히드록시-프로필)-히드록심산할라이드의 제조방법 | |
US4172141A (en) | N-(naphthylethyl)imidazole derivatives | |
DE69011620T2 (de) | Iso- und heterozyklische Phenylsulfonamide. | |
EP0303348B1 (en) | 2-amino-5-hydroxy-4-pyrimidones | |
EP0412529B1 (en) | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | |
US4908454A (en) | Process of producing guanidinothiazole derivatives | |
KR940008923B1 (ko) | 아미노아세토니트릴 유도체 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |