FR2471787A1 - Melanges de cephalexine et de bioxyde de silicium a introduire dans des gelules pharmaceutiques, leur procede de preparation et gelules ainsi obtenues - Google Patents
Melanges de cephalexine et de bioxyde de silicium a introduire dans des gelules pharmaceutiques, leur procede de preparation et gelules ainsi obtenues Download PDFInfo
- Publication number
- FR2471787A1 FR2471787A1 FR8027032A FR8027032A FR2471787A1 FR 2471787 A1 FR2471787 A1 FR 2471787A1 FR 8027032 A FR8027032 A FR 8027032A FR 8027032 A FR8027032 A FR 8027032A FR 2471787 A1 FR2471787 A1 FR 2471787A1
- Authority
- FR
- France
- Prior art keywords
- cephalexin
- mixture
- weight
- lubricant
- colloidal silicon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims 15
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 title claims 6
- ZAIPMKNFIOOWCQ-UEKVPHQBSA-N cephalexin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C)C(O)=O)=CC=CC=C1 ZAIPMKNFIOOWCQ-UEKVPHQBSA-N 0.000 title claims 5
- 229940106164 cephalexin Drugs 0.000 title claims 5
- 239000000314 lubricant Substances 0.000 title claims 5
- 235000019359 magnesium stearate Nutrition 0.000 title claims 3
- 239000002775 capsule Substances 0.000 title claims 2
- 229910052710 silicon Inorganic materials 0.000 title claims 2
- 239000010703 silicon Substances 0.000 title claims 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 5
- 229940075614 colloidal silicon dioxide Drugs 0.000 claims 5
- 238000000034 method Methods 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7944279 | 1979-12-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2471787A1 true FR2471787A1 (fr) | 1981-06-26 |
| FR2471787B1 FR2471787B1 (enExample) | 1984-05-18 |
Family
ID=10510032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8027032A Granted FR2471787A1 (fr) | 1979-12-21 | 1980-12-19 | Melanges de cephalexine et de bioxyde de silicium a introduire dans des gelules pharmaceutiques, leur procede de preparation et gelules ainsi obtenues |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5699415A (enExample) |
| BE (1) | BE886778A (enExample) |
| DE (1) | DE3048039A1 (enExample) |
| FR (1) | FR2471787A1 (enExample) |
| IT (1) | IT1144023B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS591417A (ja) * | 1982-06-28 | 1984-01-06 | Toyo Jozo Co Ltd | 持続性セフアレキシン錠およびその製造法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1007465A (en) * | 1961-06-09 | 1965-10-13 | Eastman Kodak Co | Process for preparing a dry, finely divided gelatin particle product containing a medicament |
| GB1128275A (en) * | 1966-04-08 | 1968-09-25 | Jefferson Chem Co Inc | Method for the treatment of piperazine and salts thereof |
| FR2356430A1 (fr) * | 1976-06-29 | 1978-01-27 | Kockums Chem | Procede et composition pour reduire la dose d'une substance biologiquement active tout en maintenant son effet biologique |
-
1980
- 1980-12-19 FR FR8027032A patent/FR2471787A1/fr active Granted
- 1980-12-19 DE DE19803048039 patent/DE3048039A1/de not_active Withdrawn
- 1980-12-19 JP JP18118080A patent/JPS5699415A/ja active Pending
- 1980-12-19 IT IT50416/80A patent/IT1144023B/it active
- 1980-12-19 BE BE0/203254A patent/BE886778A/fr not_active IP Right Cessation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1007465A (en) * | 1961-06-09 | 1965-10-13 | Eastman Kodak Co | Process for preparing a dry, finely divided gelatin particle product containing a medicament |
| GB1128275A (en) * | 1966-04-08 | 1968-09-25 | Jefferson Chem Co Inc | Method for the treatment of piperazine and salts thereof |
| FR2356430A1 (fr) * | 1976-06-29 | 1978-01-27 | Kockums Chem | Procede et composition pour reduire la dose d'une substance biologiquement active tout en maintenant son effet biologique |
Non-Patent Citations (1)
| Title |
|---|
| CHEMICAL ABSTRACTS, vol. 91, no. 2, 9 juillet 1979, page 274, no. 9430b, Columbus Ohio (USA); * |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5699415A (en) | 1981-08-10 |
| FR2471787B1 (enExample) | 1984-05-18 |
| IT1144023B (it) | 1986-10-29 |
| DE3048039A1 (de) | 1981-09-10 |
| IT8050416A0 (it) | 1980-12-19 |
| BE886778A (fr) | 1981-06-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |