FR2455889A1 - PHENYLCYCLOHEXANE DERIVATIVES HAVING ANTIDEPRESSIVE ACTION - Google Patents

PHENYLCYCLOHEXANE DERIVATIVES HAVING ANTIDEPRESSIVE ACTION

Info

Publication number
FR2455889A1
FR2455889A1 FR8010379A FR8010379A FR2455889A1 FR 2455889 A1 FR2455889 A1 FR 2455889A1 FR 8010379 A FR8010379 A FR 8010379A FR 8010379 A FR8010379 A FR 8010379A FR 2455889 A1 FR2455889 A1 FR 2455889A1
Authority
FR
France
Prior art keywords
group
antidepressive action
linked
phenylcyclohexane derivatives
phenylcyclohexane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR8010379A
Other languages
French (fr)
Inventor
Massimo Carissimi
Franco Ravenna
Piergiuseppe De Meglio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Maggioni Farmaceutici SpA
Original Assignee
Maggioni Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maggioni Farmaceutici SpA filed Critical Maggioni Farmaceutici SpA
Publication of FR2455889A1 publication Critical patent/FR2455889A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/562—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
    • C07C45/565—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom by reaction with hexamethylene-tetramine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/527—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings
    • C07C49/563—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Lubricants (AREA)

Abstract

NOUVEAUX ANTIDEPRIMANTS ET AGENTS D'EQUILIBRE DU SYSTEME NERVEUX CENTRAL REPRESENTES PAR LA FORMULE GENERALE: (CF DESSIN DANS BOPI) OU A ET B SONT DIFFERENTS ET PEUVENT ETRE CHOISIS DANS LE GROUPE PHENYL OU CYCLOHEXYL, X ETANT UN RESIDU ALIPHATIQUE ET Y ET Y CHOISIS DANS LE GROUPE COMPOSE DE L'HYDROGENE OU D'UN RADICAL ALKYL EVENTUELLEMENT LIE A UN GROUPEMENT -CN OU PEUVENT ETRE REMPLACES PAR UN SEUL RADICAL LIE A L'ATOME D'AZOTE PAR UNE DOUBLE LIAISON.NEW ANTI-PRIMERS AND AGENTS OF BALANCE OF THE CENTRAL NERVOUS SYSTEM REPRESENTED BY THE GENERAL FORMULA: (CF DRAWING IN BOPI) OR A AND B ARE DIFFERENT AND CAN BE CHOSEN FROM THE PHENYL OR CYCLOHEXYL GROUP, X BEING A CHIPHAIS AND Y AL RESIDU IN THE GROUP COMPOSED OF HYDROGEN OR OF A RADICAL ALKYL POSSIBLY LINKED TO A -CN GROUP OR MAY BE REPLACED BY A SINGLE RADICAL LINKED TO THE NITROGEN ATOM BY A DOUBLE LINK.

FR8010379A 1979-05-09 1980-05-09 PHENYLCYCLOHEXANE DERIVATIVES HAVING ANTIDEPRESSIVE ACTION Withdrawn FR2455889A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22483/79A IT1113391B (en) 1979-05-09 1979-05-09 PHENYLCYCLOHEXANIC DERIVATIVES WITH ANTI-PRESSURE ACTIVITY

Publications (1)

Publication Number Publication Date
FR2455889A1 true FR2455889A1 (en) 1980-12-05

Family

ID=11196874

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8010379A Withdrawn FR2455889A1 (en) 1979-05-09 1980-05-09 PHENYLCYCLOHEXANE DERIVATIVES HAVING ANTIDEPRESSIVE ACTION

Country Status (5)

Country Link
JP (1) JPS568351A (en)
DE (1) DE3017815A1 (en)
FR (1) FR2455889A1 (en)
GB (1) GB2050358A (en)
IT (1) IT1113391B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0376850A1 (en) * 1988-12-30 1990-07-04 Elf Sanofi Benzene derivates, their preparation and pharmaceutical compositions containing them
WO1998004251A1 (en) * 1996-07-29 1998-02-05 Sanofi Use of amines to produce drugs for preventing tumour cell proliferation

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253501A3 (en) * 1986-07-16 1990-04-04 Imperial Chemical Industries Plc N-disubstituted cycloalkylmethyl amines useful as fungicides

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE477026A (en) *
US3076005A (en) * 1961-03-06 1963-01-29 Labofina Sa Nickel thiocyanate complexes of the werner type
FR2249659A1 (en) * 1973-11-02 1975-05-30 Clin Midy
JPS5223051A (en) * 1975-08-09 1977-02-21 Takeda Chem Ind Ltd Preparation of cyclohexane derivatives

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE477026A (en) *
US3076005A (en) * 1961-03-06 1963-01-29 Labofina Sa Nickel thiocyanate complexes of the werner type
FR2249659A1 (en) * 1973-11-02 1975-05-30 Clin Midy
JPS5223051A (en) * 1975-08-09 1977-02-21 Takeda Chem Ind Ltd Preparation of cyclohexane derivatives

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CA1977 *
EXBK/50 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0376850A1 (en) * 1988-12-30 1990-07-04 Elf Sanofi Benzene derivates, their preparation and pharmaceutical compositions containing them
FR2641276A1 (en) * 1988-12-30 1990-07-06 Sanofi Sa BENZENE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
US5354781A (en) * 1988-12-30 1994-10-11 Sanofi Benzene derivatives, their preparation and pharmaceutical compositions in which they are present
US5449693A (en) * 1988-12-30 1995-09-12 Sanofi Benzene derivatives, their preparation and pharmaceutical compositions in which they are present
WO1998004251A1 (en) * 1996-07-29 1998-02-05 Sanofi Use of amines to produce drugs for preventing tumour cell proliferation

Also Published As

Publication number Publication date
IT1113391B (en) 1986-01-20
IT7922483A0 (en) 1979-05-09
JPS568351A (en) 1981-01-28
DE3017815A1 (en) 1980-11-27
GB2050358A (en) 1981-01-07

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Legal Events

Date Code Title Description
ST Notification of lapse