FR2439177A1 - METHOD FOR SYNTHESIS OF KETONIC ACIDS AND ESTERS - Google Patents
METHOD FOR SYNTHESIS OF KETONIC ACIDS AND ESTERSInfo
- Publication number
- FR2439177A1 FR2439177A1 FR7925756A FR7925756A FR2439177A1 FR 2439177 A1 FR2439177 A1 FR 2439177A1 FR 7925756 A FR7925756 A FR 7925756A FR 7925756 A FR7925756 A FR 7925756A FR 2439177 A1 FR2439177 A1 FR 2439177A1
- Authority
- FR
- France
- Prior art keywords
- esters
- acid
- ketonic acids
- organic solvent
- synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
- C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
Abstract
ON PREPARE DES ACIDES OU DES ESTERS CETONIQUES, OU LEURS PRECURSEURS, PAR EXEMPLE LES DIESTERS DE L'ACIDE ACETONE DICARBOXYLIQUE, EN FAISANT REAGIR UN ACIDE A-HYDROXYLE, PAR EXEMPLE L'ACIDE CITRIQUE, OU UN DERIVE DE CET ACIDE, AVEC UN ACIDE MINERAL ANHYDRE OU UN ANHYDRIDE D'ACIDE CARBOXYLIQUE EN PRESENCE D'UN SOLVANT ORGANIQUE INERTE ET NON MISCIBLE A L'EAU. IL EST POSSIBLE DE DIMINUER LES DIFFICULTES DE FABRICATION QUAND ON PREPARE LES ACIDES OU ESTERS CETONIQUES DANS UN MILIEU REACTIONNEL CONTENANT UN TEL SOLVANT ORGANIQUE. LES ESTERS DE L'ACIDE ACETONE DICARBOXYLIQUE SONT UTILES COMME CATALYSEURS POUR LA POLYMERISATION DU CHLOROPRENE, ET ON PEUT EGALEMENT LES FAIRE REAGIR AVEC DES AMINES PRIMAIRES ET UNE HALOACETONE POUR FORMER DES ESTERS DE PYRROLE SUBSTITUES QUI SONT DES PRODUITS PHARMACEUTIQUES.KETONIC ACIDS OR ESTERS, OR THEIR PRECURSORS, FOR EXAMPLE ACETONE DICARBOXYLIC ACID DIESTERS, ARE PREPARED BY REACTING AN A-HYDROXYL ACID, FOR EXAMPLE CITRIC ACID, OR A DERIVATIVE OF THIS ACID, WITH AN ACID. MINERAL ANHYDROUS OR A CARBOXYLIC ACID ANHYDRIDE IN THE PRESENCE OF AN INERT ORGANIC SOLVENT AND NOT MISCIBLE TO WATER. IT IS POSSIBLE TO REDUCE MANUFACTURING DIFFICULTIES WHEN PREPARING KETONIC ACIDS OR ESTERS IN A REACTIONAL MEDIUM CONTAINING SUCH ORGANIC SOLVENT. ACETONE DICARBOXYLIC ACID ESTERS ARE USEFUL AS CATALYSTS FOR POLYMERIZATION OF CHLOROPRENE, AND CAN ALSO BE REACTED WITH PRIMARY AMINES AND HALOACETONE TO FORM PYRROLE ESTERS SUBSTITUTE FOR PHARMACEUTICALS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95268178A | 1978-10-19 | 1978-10-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2439177A1 true FR2439177A1 (en) | 1980-05-16 |
Family
ID=25493135
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7925756A Withdrawn FR2439177A1 (en) | 1978-10-19 | 1979-10-17 | METHOD FOR SYNTHESIS OF KETONIC ACIDS AND ESTERS |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS5594336A (en) |
BE (1) | BE879537A (en) |
DE (1) | DE2942105A1 (en) |
FI (1) | FI793220A (en) |
FR (1) | FR2439177A1 (en) |
GB (1) | GB2033391A (en) |
NL (1) | NL7907734A (en) |
SE (1) | SE7908597L (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3765899D1 (en) * | 1986-08-29 | 1990-12-06 | American Cyanamid Co | METHOD FOR PRODUCING ANILINOFUMARATE AND 2,3-CHINOLINE DICARBONIC ACID. |
ATE412625T1 (en) * | 2003-04-10 | 2008-11-15 | Egis Gyogyszergyar Nyilvanosan | METHOD FOR PRODUCING DIALKYL 3-OXOGLUTARATES |
EP2895613A2 (en) * | 2012-09-14 | 2015-07-22 | BioAmber Inc. | Alternative pathways to adipates and adipic acid by combined fermentation and catalytic methods |
CN103288628B (en) * | 2013-06-09 | 2016-06-01 | 重庆邮电大学 | Citric acid hydrogen peroxide oxidation prepares the method for 1,3-��-ketoglutaric acid diester and intermediate thereof |
CN109053413A (en) * | 2018-08-04 | 2018-12-21 | 许昌恒生制药有限公司 | A kind of preparation method of cholinolytic class pharmaceutical intermediate |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2848480A (en) * | 1953-02-19 | 1958-08-19 | Smith New York Co Inc | Production of keto esters |
US2887508A (en) * | 1958-07-17 | 1959-05-19 | Pfizer & Co C | Lower alkyl ester of acetonedicarboxylic acid |
FR1203748A (en) * | 1957-11-21 | 1960-01-20 | Pfizer & Co C | Improvements to the processes for preparing acetonedicarboxylic acid and its esters |
DE1160841B (en) * | 1961-01-16 | 1964-01-09 | Boehringer Sohn Ingelheim | Process for the preparation of acetone dicarboxylic acid and its alkyl esters from citric acid |
-
1979
- 1979-10-17 FR FR7925756A patent/FR2439177A1/en not_active Withdrawn
- 1979-10-17 FI FI793220A patent/FI793220A/en not_active Application Discontinuation
- 1979-10-17 SE SE7908597A patent/SE7908597L/en not_active Application Discontinuation
- 1979-10-17 JP JP13410579A patent/JPS5594336A/en active Pending
- 1979-10-18 DE DE19792942105 patent/DE2942105A1/en not_active Withdrawn
- 1979-10-18 GB GB7936181A patent/GB2033391A/en not_active Withdrawn
- 1979-10-19 NL NL7907734A patent/NL7907734A/en not_active Application Discontinuation
- 1979-10-19 BE BE0/197746A patent/BE879537A/en unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2848480A (en) * | 1953-02-19 | 1958-08-19 | Smith New York Co Inc | Production of keto esters |
FR1203748A (en) * | 1957-11-21 | 1960-01-20 | Pfizer & Co C | Improvements to the processes for preparing acetonedicarboxylic acid and its esters |
US2887508A (en) * | 1958-07-17 | 1959-05-19 | Pfizer & Co C | Lower alkyl ester of acetonedicarboxylic acid |
DE1160841B (en) * | 1961-01-16 | 1964-01-09 | Boehringer Sohn Ingelheim | Process for the preparation of acetone dicarboxylic acid and its alkyl esters from citric acid |
Also Published As
Publication number | Publication date |
---|---|
NL7907734A (en) | 1980-04-22 |
JPS5594336A (en) | 1980-07-17 |
BE879537A (en) | 1980-02-15 |
FI793220A (en) | 1980-04-20 |
GB2033391A (en) | 1980-05-21 |
SE7908597L (en) | 1980-04-20 |
DE2942105A1 (en) | 1980-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |