FR2424256A1 - Nouveaux derives d'acides naphtalenetris (sulfonamidobenzenemono-, di- ou tricarboxyliques), utiles notamment comme inhibiteurs du complement, et leur procede de preparation - Google Patents

Nouveaux derives d'acides naphtalenetris (sulfonamidobenzenemono-, di- ou tricarboxyliques), utiles notamment comme inhibiteurs du complement, et leur procede de preparation

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Publication number
FR2424256A1
FR2424256A1 FR7812564A FR7812564A FR2424256A1 FR 2424256 A1 FR2424256 A1 FR 2424256A1 FR 7812564 A FR7812564 A FR 7812564A FR 7812564 A FR7812564 A FR 7812564A FR 2424256 A1 FR2424256 A1 FR 2424256A1
Authority
FR
France
Prior art keywords
tris
treating
useful
inflammatory processes
membrane damage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7812564A
Other languages
English (en)
Other versions
FR2424256B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Priority to FR7812564A priority Critical patent/FR2424256A1/fr
Publication of FR2424256A1 publication Critical patent/FR2424256A1/fr
Application granted granted Critical
Publication of FR2424256B1 publication Critical patent/FR2424256B1/fr
Granted legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C205/60—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms in ortho-position to the carboxyl group, e.g. nitro-salicylic acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'INVENTION CONCERNE DE NOUVEAUX DERIVES D'ACIDES NAPHTALENE-TRIS (SULFONAMIDOBENZENEMONO-, DI- OU TRICARBOXYLIQUES), UTILES NOTAMMENT COMME INHIBITEURS DE COMPLEMENT, ET LEURS PROCEDES DE PREPARATION. LES MEDICAMENTS SELON L'INVENTION CONSISTENT EN COMPOSES DE FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE R EST UN ATOME D'HYDROGENE OU UN GROUPE METHYLE; R EST UN ATOME D'HYDROGENE OU UN GROUPE CARBOXY OU UN GROUPE COOR DANS LEQUEL R EST UN METAL ALCALIN OU ALCALINO-TERREUX; R EST UN ATOME D'HYDROGENE OU UN GROUPE HYDROXY OU UN GROUPE COOR DANS LEQUEL R EST TEL QUE DEFINI CI-DESSUS, AVEC LA CONDITION QUE CHAQUE GROUPE PHENYLE DOIT PORTER AU MOINS UN GROUPE COOR; ET LEURS SELS D'ADDITION D'ACIDES ET SELS D'AMMONIUM QUATERNAIRE NON TOXIQUES ACCEPTABLES EN PHARMACOLOGIE. LA DOSE JOURNALIERE HABITUELLE POUR UN HUMAIN DE 70KG VARIE D'ENVIRON 350 MG A 3,5 G, EN DOSES UNITAIRES DE L'ACIDE OU DE SEL CONTENANT 0,5 A 500 MG D'INGREDIENT ACTIF.
FR7812564A 1978-04-27 1978-04-27 Nouveaux derives d'acides naphtalenetris (sulfonamidobenzenemono-, di- ou tricarboxyliques), utiles notamment comme inhibiteurs du complement, et leur procede de preparation Granted FR2424256A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7812564A FR2424256A1 (fr) 1978-04-27 1978-04-27 Nouveaux derives d'acides naphtalenetris (sulfonamidobenzenemono-, di- ou tricarboxyliques), utiles notamment comme inhibiteurs du complement, et leur procede de preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7812564A FR2424256A1 (fr) 1978-04-27 1978-04-27 Nouveaux derives d'acides naphtalenetris (sulfonamidobenzenemono-, di- ou tricarboxyliques), utiles notamment comme inhibiteurs du complement, et leur procede de preparation

Publications (2)

Publication Number Publication Date
FR2424256A1 true FR2424256A1 (fr) 1979-11-23
FR2424256B1 FR2424256B1 (fr) 1980-10-31

Family

ID=9207680

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7812564A Granted FR2424256A1 (fr) 1978-04-27 1978-04-27 Nouveaux derives d'acides naphtalenetris (sulfonamidobenzenemono-, di- ou tricarboxyliques), utiles notamment comme inhibiteurs du complement, et leur procede de preparation

Country Status (1)

Country Link
FR (1) FR2424256A1 (fr)

Also Published As

Publication number Publication date
FR2424256B1 (fr) 1980-10-31

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