FR2401146A1 - LIPOGENESIS INHIBITORS BASED ON 2,3-DIHYDROBENZOFURAN DERIVATIVES - Google Patents

LIPOGENESIS INHIBITORS BASED ON 2,3-DIHYDROBENZOFURAN DERIVATIVES

Info

Publication number
FR2401146A1
FR2401146A1 FR7819308A FR7819308A FR2401146A1 FR 2401146 A1 FR2401146 A1 FR 2401146A1 FR 7819308 A FR7819308 A FR 7819308A FR 7819308 A FR7819308 A FR 7819308A FR 2401146 A1 FR2401146 A1 FR 2401146A1
Authority
FR
France
Prior art keywords
inhibitors based
dihydrobenzofuran derivatives
lipogenesis inhibitors
derivatives
lipogenesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7819308A
Other languages
French (fr)
Other versions
FR2401146B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shell Internationale Research Maatschappij BV
Original Assignee
Shell Internationale Research Maatschappij BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shell Internationale Research Maatschappij BV filed Critical Shell Internationale Research Maatschappij BV
Publication of FR2401146A1 publication Critical patent/FR2401146A1/en
Application granted granted Critical
Publication of FR2401146B1 publication Critical patent/FR2401146B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/008—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with tri- or tetrahalomethyl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

L'invention concerne des dérivés de 2,3-dihydrofuranne. Des compositions comprenant un dérivé de 5 R- ou 6 R- benzofuranne de formule :The invention relates to derivatives of 2,3-dihydrofuran. Compositions comprising a 5 R- or 6 R- benzofuran derivative of formula:

FR7819308A 1977-06-30 1978-06-28 LIPOGENESIS INHIBITORS BASED ON 2,3-DIHYDROBENZOFURAN DERIVATIVES Granted FR2401146A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81164777A 1977-06-30 1977-06-30
US81789877A 1977-07-21 1977-07-21

Publications (2)

Publication Number Publication Date
FR2401146A1 true FR2401146A1 (en) 1979-03-23
FR2401146B1 FR2401146B1 (en) 1983-03-18

Family

ID=27123512

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7819308A Granted FR2401146A1 (en) 1977-06-30 1978-06-28 LIPOGENESIS INHIBITORS BASED ON 2,3-DIHYDROBENZOFURAN DERIVATIVES

Country Status (9)

Country Link
AU (1) AU520682B2 (en)
DD (1) DD141023A5 (en)
DE (1) DE2828396A1 (en)
DK (1) DK292678A (en)
FR (1) FR2401146A1 (en)
GB (1) GB2007973B (en)
IT (1) IT1113147B (en)
NL (1) NL7806944A (en)
SE (1) SE7807338L (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0019955A1 (en) * 1979-05-16 1980-12-10 Shell Internationale Researchmaatschappij B.V. Benzofurancarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions
US4229467A (en) * 1979-08-16 1980-10-21 Richardson-Merrell Inc. Alkoxy benzofuran carboxylic acids and salts and esters thereof as hypolipidemic agents
EP0146243A1 (en) * 1983-10-31 1985-06-26 Merck Frosst Canada Inc. Lipoxygenase inhibitors
US4663347A (en) * 1983-10-31 1987-05-05 Merck Frosst Canada, Inc. Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis
US4933351A (en) * 1983-10-31 1990-06-12 Merck Frosst Canada, Inc. Benzofuran 2-carbox amides useful as inhibitors of leukoriene biosynthesis
US4822803A (en) * 1983-10-31 1989-04-18 Merck Frosst Canada, Inc. Benzofuran 2-carboxylic acid hydrazides useful as inhibitors of leukotriene biosynthesis
JP3093507B2 (en) * 1993-02-15 2000-10-03 キヤノン株式会社 Liquid crystal compound, liquid crystal composition containing the same, liquid crystal element having the same, display method and display device using them

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/76 *

Also Published As

Publication number Publication date
GB2007973A (en) 1979-05-31
AU3751578A (en) 1980-01-03
NL7806944A (en) 1979-01-03
SE7807338L (en) 1978-12-31
IT7825091A0 (en) 1978-06-28
AU520682B2 (en) 1982-02-18
DD141023A5 (en) 1980-04-09
DE2828396A1 (en) 1979-01-11
DK292678A (en) 1978-12-31
GB2007973B (en) 1982-04-21
IT1113147B (en) 1986-01-20
FR2401146B1 (en) 1983-03-18

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Legal Events

Date Code Title Description
ST Notification of lapse