FR2364207A1 - Procede ameliore pour la preparation de 1,4-benzodiazepines - Google Patents
Procede ameliore pour la preparation de 1,4-benzodiazepinesInfo
- Publication number
- FR2364207A1 FR2364207A1 FR7627149A FR7627149A FR2364207A1 FR 2364207 A1 FR2364207 A1 FR 2364207A1 FR 7627149 A FR7627149 A FR 7627149A FR 7627149 A FR7627149 A FR 7627149A FR 2364207 A1 FR2364207 A1 FR 2364207A1
- Authority
- FR
- France
- Prior art keywords
- benzophenone
- reacting
- ammonium salt
- haloethyl
- tetr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- GUJAGMICFDYKNR-UHFFFAOYSA-N 1,4-benzodiazepine Chemical compound N1C=CN=CC2=CC=CC=C12 GUJAGMICFDYKNR-UHFFFAOYSA-N 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003863 ammonium salts Chemical class 0.000 title abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 title 1
- 150000001412 amines Chemical class 0.000 title 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 title 1
- 239000002904 solvent Substances 0.000 title 1
- 239000012965 benzophenone Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 125000004836 hexamethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[*:1] 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7627149A FR2364207A1 (fr) | 1976-09-09 | 1976-09-09 | Procede ameliore pour la preparation de 1,4-benzodiazepines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7627149A FR2364207A1 (fr) | 1976-09-09 | 1976-09-09 | Procede ameliore pour la preparation de 1,4-benzodiazepines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2364207A1 true FR2364207A1 (fr) | 1978-04-07 |
| FR2364207B1 FR2364207B1 (enrdf_load_stackoverflow) | 1979-07-27 |
Family
ID=9177533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7627149A Granted FR2364207A1 (fr) | 1976-09-09 | 1976-09-09 | Procede ameliore pour la preparation de 1,4-benzodiazepines |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2364207A1 (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7527183B2 (en) | 2002-08-21 | 2009-05-05 | Project S.A.S. Di Massimo Menichelli & C. | Cardboard tool for opening glass ampoules |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2144868A1 (enrdf_load_stackoverflow) * | 1971-07-08 | 1973-02-16 | Hoffmann La Roche |
-
1976
- 1976-09-09 FR FR7627149A patent/FR2364207A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2144868A1 (enrdf_load_stackoverflow) * | 1971-07-08 | 1973-02-16 | Hoffmann La Roche |
Non-Patent Citations (1)
| Title |
|---|
| NEANT * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7527183B2 (en) | 2002-08-21 | 2009-05-05 | Project S.A.S. Di Massimo Menichelli & C. | Cardboard tool for opening glass ampoules |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2364207B1 (enrdf_load_stackoverflow) | 1979-07-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FR2391990A1 (fr) | Procede pour la preparation de fluorobenzenes par reaction de chlorobenzenes avec le fluorure de potassium | |
| GB1312536A (en) | Hydantoin derivatives | |
| GB1148718A (en) | Phenyl benzoxazocineones and their preparation | |
| FR2364207A1 (fr) | Procede ameliore pour la preparation de 1,4-benzodiazepines | |
| FR2358378A1 (fr) | Systemes aqueux chimioluminescents | |
| FR2417498A1 (fr) | N-(1-ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoyl-benzamide levogyre, sa preparation et ses utilisations therapeutiques | |
| DE69807073D1 (de) | Herstellung von tri-iodo-benzol-verbindungen | |
| Nishiguchi et al. | Acid-catalyzed isomerization of 1-acyl-and 1-thioacylaziridines. II. Orientation of ring opening | |
| FR2381746A1 (fr) | Nouveaux derives encephaliniques a la methionine | |
| BAUER et al. | Synthesis of Aminoisoxazolones from α-Cyano Esters and Hydroxylamine1 | |
| FR2452925A1 (fr) | Composition pharmaceutique contenant un compose 1,3-5 substitue du biuret | |
| FR2361372A1 (fr) | Procede de preparation de la 2,4-diamino-5-(3', 4', 5'-trimethoxybenzyl)-pyrimidine | |
| Johnson et al. | Polyfunctional aliphatic compounds. V. The cyclization of dinitriles by halogen acids. A new synthesis of imidazoles | |
| US3917634A (en) | 1-(2,6-Dimethyl-2-octen-8-yl)-2-substituted or unsubstituted phenylimidazoles | |
| Hoffmann et al. | Transition States in the Gas Phase and in Solution | |
| GB1138888A (en) | The manufacture of benzdiaz[1,4]epines | |
| US4748264A (en) | Substituted alpha-[2'-tricyclo[3.3.1.13,7 ]-decylidene]benzeneacetonitrile derivatives | |
| GB1374404A (en) | Phenylhydrazone derivatives | |
| FR2453181A1 (fr) | Le 6-chloro-6-desoxy-mannose et son utilisation dans des compositions possedant une action inhibitrice de la fecondite masculine | |
| GB1428578A (en) | Methylene-bridged diaryl diisocyanates | |
| Akutagawa et al. | Copper catalyzed reactions of S, S-diaryl-N-tosylsulfilimines with sulfoxides: new synthesis of N-tosylsulfoximines | |
| US3530188A (en) | Bromomethylbenzophenones and related compounds | |
| JPS54112827A (en) | Preparation of 1,3,5-trichlorobenzene | |
| FR2406226A1 (fr) | Materiaux formant l'image a l'argent pouvant etre developpes a chaud | |
| US3584062A (en) | Alpha-methyl-beta-nitro-m-(trifluoromethyl)styrene |