FR2338044A1 - Glycerophosphates de papaverine et d'ethaverine - Google Patents
Glycerophosphates de papaverine et d'ethaverineInfo
- Publication number
- FR2338044A1 FR2338044A1 FR7600793A FR7600793A FR2338044A1 FR 2338044 A1 FR2338044 A1 FR 2338044A1 FR 7600793 A FR7600793 A FR 7600793A FR 7600793 A FR7600793 A FR 7600793A FR 2338044 A1 FR2338044 A1 FR 2338044A1
- Authority
- FR
- France
- Prior art keywords
- alpha
- ethaverine
- hydrochlorides
- glycerophosphate
- degrees
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- XQYZDYMELSJDRZ-UHFFFAOYSA-N papaverine Chemical compound C1=C(OC)C(OC)=CC=C1CC1=NC=CC2=CC(OC)=C(OC)C=C12 XQYZDYMELSJDRZ-UHFFFAOYSA-N 0.000 title abstract 4
- 229960005269 ethaverine Drugs 0.000 title abstract 3
- 150000003840 hydrochlorides Chemical class 0.000 title abstract 3
- ZOWYFYXTIWQBEP-UHFFFAOYSA-N 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxyisoquinoline Chemical compound C1=C(OCC)C(OCC)=CC=C1CC1=NC=CC2=CC(OCC)=C(OCC)C=C12 ZOWYFYXTIWQBEP-UHFFFAOYSA-N 0.000 title abstract 2
- 229930008281 A03AD01 - Papaverine Natural products 0.000 title abstract 2
- 230000003170 musculotropic effect Effects 0.000 title abstract 2
- 229960001789 papaverine Drugs 0.000 title abstract 2
- 230000002048 spasmolytic effect Effects 0.000 title abstract 2
- 150000002315 glycerophosphates Chemical class 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 4
- AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 abstract 3
- DHCLVCXQIBBOPH-UHFFFAOYSA-N Glycerol 2-phosphate Chemical compound OCC(CO)OP(O)(O)=O DHCLVCXQIBBOPH-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- AWUCVROLDVIAJX-GSVOUGTGSA-N sn-glycerol 3-phosphate Chemical compound OC[C@@H](O)COP(O)(O)=O AWUCVROLDVIAJX-GSVOUGTGSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 125000002091 cationic group Chemical group 0.000 abstract 1
- GEKBIENFFVFKRG-UHFFFAOYSA-L disodium;2,3-dihydroxypropyl phosphate Chemical compound [Na+].[Na+].OCC(O)COP([O-])([O-])=O GEKBIENFFVFKRG-UHFFFAOYSA-L 0.000 abstract 1
- 238000001953 recrystallisation Methods 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7600793A FR2338044A1 (fr) | 1976-01-14 | 1976-01-14 | Glycerophosphates de papaverine et d'ethaverine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7600793A FR2338044A1 (fr) | 1976-01-14 | 1976-01-14 | Glycerophosphates de papaverine et d'ethaverine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2338044A1 true FR2338044A1 (fr) | 1977-08-12 |
| FR2338044B1 FR2338044B1 (enrdf_load_stackoverflow) | 1980-04-30 |
Family
ID=9167892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7600793A Granted FR2338044A1 (fr) | 1976-01-14 | 1976-01-14 | Glycerophosphates de papaverine et d'ethaverine |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2338044A1 (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004017971A1 (de) * | 2002-08-08 | 2004-03-04 | Ursapharm Arzneimittel Gmbh & Co. Kg | Verwendung von papaverinartigem vasodilatator und pharmazeutische zusammensetzung |
-
1976
- 1976-01-14 FR FR7600793A patent/FR2338044A1/fr active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004017971A1 (de) * | 2002-08-08 | 2004-03-04 | Ursapharm Arzneimittel Gmbh & Co. Kg | Verwendung von papaverinartigem vasodilatator und pharmazeutische zusammensetzung |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2338044B1 (enrdf_load_stackoverflow) | 1980-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |