FR2249671A2 - 2-Aryl-4poxo-phthalazin-2-ones and their enols - as diuretics and saluretics also 2-sulpho-1-naphthols as inters therefor - Google Patents
2-Aryl-4poxo-phthalazin-2-ones and their enols - as diuretics and saluretics also 2-sulpho-1-naphthols as inters thereforInfo
- Publication number
- FR2249671A2 FR2249671A2 FR7436390A FR7436390A FR2249671A2 FR 2249671 A2 FR2249671 A2 FR 2249671A2 FR 7436390 A FR7436390 A FR 7436390A FR 7436390 A FR7436390 A FR 7436390A FR 2249671 A2 FR2249671 A2 FR 2249671A2
- Authority
- FR
- France
- Prior art keywords
- substd
- opt
- aryl
- saluretics
- diuretics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002934 diuretic Substances 0.000 title abstract 2
- 229940030606 diuretics Drugs 0.000 title abstract 2
- 230000000894 saliuretic effect Effects 0.000 title abstract 2
- PWJNDVAKQLOWRZ-UHFFFAOYSA-N 1-hydroxynaphthalene-2-sulfonic acid Chemical class C1=CC=C2C(O)=C(S(O)(=O)=O)C=CC2=C1 PWJNDVAKQLOWRZ-UHFFFAOYSA-N 0.000 title 1
- 150000002085 enols Chemical class 0.000 title 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical group C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000003435 aroyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- -1 cycloalkenylthio Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- SGBQUMZTGSQNAO-UHFFFAOYSA-N 2-hydroxynaphthalene-1-sulfonic acid Chemical compound C1=CC=CC2=C(S(O)(=O)=O)C(O)=CC=C21 SGBQUMZTGSQNAO-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000005108 alkenylthio group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000005110 aryl thio group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000004465 cycloalkenyloxy group Chemical group 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000005366 cycloalkylthio group Chemical group 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical group O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB50623/73A GB1480591A (en) | 1973-10-31 | 1973-10-31 | Substituted phthalazines and their use as therapeutic agents |
| DK229774A DK229774A (cs) | 1973-10-31 | 1974-04-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2249671A2 true FR2249671A2 (en) | 1975-05-30 |
| FR2249671B2 FR2249671B2 (cs) | 1978-08-11 |
Family
ID=26066472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7436390A Granted FR2249671A2 (en) | 1973-10-31 | 1974-10-31 | 2-Aryl-4poxo-phthalazin-2-ones and their enols - as diuretics and saluretics also 2-sulpho-1-naphthols as inters therefor |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS5077382A (cs) |
| BG (1) | BG25083A3 (cs) |
| CA (1) | CA1032163A (cs) |
| CH (1) | CH608493A5 (cs) |
| DD (1) | DD116140A6 (cs) |
| DE (1) | DE2451117A1 (cs) |
| ES (1) | ES431524A2 (cs) |
| FR (1) | FR2249671A2 (cs) |
| LU (1) | LU71199A1 (cs) |
| NL (1) | NL7414229A (cs) |
| PH (1) | PH10816A (cs) |
| RO (1) | RO69058A (cs) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE47592B1 (en) * | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
-
1974
- 1974-10-28 DE DE19742451117 patent/DE2451117A1/de active Pending
- 1974-10-29 RO RO7480359A patent/RO69058A/ro unknown
- 1974-10-29 LU LU71199A patent/LU71199A1/xx unknown
- 1974-10-30 CH CH1453274A patent/CH608493A5/xx not_active IP Right Cessation
- 1974-10-30 JP JP12531674A patent/JPS5077382A/ja active Pending
- 1974-10-30 ES ES431524A patent/ES431524A2/es not_active Expired
- 1974-10-31 BG BG028086A patent/BG25083A3/xx unknown
- 1974-10-31 FR FR7436390A patent/FR2249671A2/fr active Granted
- 1974-10-31 DD DD18207774A patent/DD116140A6/xx unknown
- 1974-10-31 CA CA212,785A patent/CA1032163A/en not_active Expired
- 1974-10-31 PH PH16477A patent/PH10816A/en unknown
- 1974-10-31 NL NL7414229A patent/NL7414229A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2249671B2 (cs) | 1978-08-11 |
| JPS5077382A (cs) | 1975-06-24 |
| PH10816A (en) | 1977-09-08 |
| BG25083A3 (en) | 1978-07-12 |
| DE2451117A1 (de) | 1975-05-22 |
| RO69058A (ro) | 1980-06-15 |
| CA1032163A (en) | 1978-05-30 |
| ES431524A2 (es) | 1977-07-01 |
| DD116140A6 (cs) | 1975-11-12 |
| NL7414229A (nl) | 1975-05-02 |
| AU7448474A (en) | 1976-04-29 |
| CH608493A5 (cs) | 1979-01-15 |
| LU71199A1 (cs) | 1975-04-17 |
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