FR2166117A1 - - Google Patents

Info

Publication number
FR2166117A1
FR2166117A1 FR7246572A FR7246572A FR2166117A1 FR 2166117 A1 FR2166117 A1 FR 2166117A1 FR 7246572 A FR7246572 A FR 7246572A FR 7246572 A FR7246572 A FR 7246572A FR 2166117 A1 FR2166117 A1 FR 2166117A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7246572A
Other versions
FR2166117B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG, Farbwerke Hoechst AG filed Critical Hoechst AG
Publication of FR2166117A1 publication Critical patent/FR2166117A1/fr
Application granted granted Critical
Publication of FR2166117B1 publication Critical patent/FR2166117B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
FR7246572A 1971-12-28 1972-12-28 Expired FR2166117B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2164919A DE2164919C3 (de) 1971-12-28 1971-12-28 Imidazolyl-(2)-carbinole, Verfahren zu ihrer Herstellung und pharmazeutische Präparate

Publications (2)

Publication Number Publication Date
FR2166117A1 true FR2166117A1 (fr) 1973-08-10
FR2166117B1 FR2166117B1 (fr) 1977-01-28

Family

ID=5829419

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7246572A Expired FR2166117B1 (fr) 1971-12-28 1972-12-28

Country Status (16)

Country Link
US (1) US4213994A (fr)
JP (1) JPS4875575A (fr)
KR (1) KR780000115B1 (fr)
AT (1) AT330764B (fr)
BE (1) BE793407A (fr)
CA (1) CA989845A (fr)
CH (3) CH615668A5 (fr)
DE (1) DE2164919C3 (fr)
ES (1) ES409907A1 (fr)
FR (1) FR2166117B1 (fr)
GB (1) GB1421774A (fr)
IL (1) IL41179A (fr)
NL (1) NL7217517A (fr)
NO (1) NO137123C (fr)
SE (1) SE412388B (fr)
ZA (1) ZA729141B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2292473A1 (fr) * 1974-11-28 1976-06-25 Expandia Sa Derives de benzimidazole utiles en tant que medicaments
FR2467847A1 (fr) * 1979-10-17 1981-04-30 Bouchara Emile Nouveaux derives de l'(hydroxybenzyl)-2 benzimidazole et les compositions pharmaceutiques en contenant
EP0034473A2 (fr) * 1980-02-13 1981-08-26 Farmos-Yhtyma Oy Imidazoles substitués, procédés pour leur préparation et compositions pharmaceutiques les contenant
FR2613720A1 (fr) * 1987-04-10 1988-10-14 Esteve Labor Dr Derives d'aryl-heteroaryl carbinols avec activite analgesique

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE793407A (fr) * 1971-12-28 1973-06-28 Hoechst Ag Imidazolyl - (2) -carbinols ayant une activite hypolipidemique et leur procede de preparation
JPS4881859A (fr) * 1972-02-04 1973-11-01
US4348404A (en) 1980-07-21 1982-09-07 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-α-polyfluoroalkyl-1H-imidazole-2-methanamines
US4372964A (en) * 1980-10-30 1983-02-08 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-1H-imidazole-2-methanols
GB2096987B (en) * 1981-04-22 1984-04-04 Farmos Oy Substituted imidazole and imidazole derivatives and their preparation and use
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
US4452987A (en) * 1981-08-20 1984-06-05 Pfizer Inc. Haloacetyl imidazoles
US4532331A (en) * 1983-04-12 1985-07-30 Smithkline Beckman Corporation 1-Benzyl-2-aminomethyl imidazole derivatives
US4661508A (en) * 1984-06-18 1987-04-28 Eli Lilly And Company Aromatase inhibiting α,α-diphenyl-4(5)imidazole-methanes or -ethanes
JPS61145165A (ja) * 1984-12-18 1986-07-02 Mitsubishi Petrochem Co Ltd ベンズイミダゾ−ル誘導体の製造法
US4869838A (en) * 1988-08-25 1989-09-26 Exxon Research And Engineering Company Bis imidazole ethers as metal deactivators
DE4217124A1 (de) * 1992-05-23 1993-11-25 Roehm Gmbh Verfahren zur Herstellung von endständig Stickstoffheterocyclus-substituiertem (Meth)acrylsäureester
US5455359B1 (en) * 1993-10-01 1998-05-05 Res Corp Technologies Inc Metal ion binding monomer and polymer
AU5513298A (en) * 1996-12-20 1998-07-17 Bristol-Myers Squibb Company Heterocyclic inhibitors of microsomal triglyceride transfer protein and method
AU5314900A (en) * 1999-06-04 2000-12-28 Elan Pharma International Limited Compositions and methods for inhibiting cell death
DE19951701A1 (de) 1999-10-27 2001-05-03 Aventis Pharma Gmbh Verwendung von 2-Imidazolyl-substituierten Carbinolen zur Herstellung eines Medikaments zur Behandlung oder Prophylaxe von durch ischämischen Zuständen bewirkten Krankheiten
US6489477B1 (en) 1999-10-29 2002-12-03 Merck & Co., Inc. 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
US6291499B1 (en) 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
US6432976B1 (en) 1999-10-29 2002-08-13 Merck & Co., Inc. 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
US6380205B1 (en) 1999-10-29 2002-04-30 Merck & Co., Inc. 2-cyclohexyl quinazoline NMDA/NR2B antagonists
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6495561B2 (en) 1999-10-29 2002-12-17 Merck & Co., Inc. 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
US6316474B1 (en) 1999-10-29 2001-11-13 Merck & Co., Inc. 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
ES2402305T3 (es) 2006-01-24 2013-04-30 Janssen Pharmaceutica N.V. Benzimidazolas 2-sustituidas nuevas como moduladores del receptor de andrógeno selectivo (SARMS)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3331739A (en) * 1961-11-01 1967-07-18 Merck & Co Inc 2-substituted benzimidazoles and their use in the inhibition of echo 6 and poliomyelitis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652579A (en) * 1969-06-26 1972-03-28 Hoffmann La Roche 1-methyl-2-substituted 5-nitroimidazoles
BE793407A (fr) * 1971-12-28 1973-06-28 Hoechst Ag Imidazolyl - (2) -carbinols ayant une activite hypolipidemique et leur procede de preparation
US3812189A (en) * 1972-07-24 1974-05-21 American Cyanamid Co N-(2,2-diloweralkoxyalkyl)-2,2-dilower-alkoxyloweralkanamidines and their acid addition salts

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3331739A (en) * 1961-11-01 1967-07-18 Merck & Co Inc 2-substituted benzimidazoles and their use in the inhibition of echo 6 and poliomyelitis

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2292473A1 (fr) * 1974-11-28 1976-06-25 Expandia Sa Derives de benzimidazole utiles en tant que medicaments
FR2467847A1 (fr) * 1979-10-17 1981-04-30 Bouchara Emile Nouveaux derives de l'(hydroxybenzyl)-2 benzimidazole et les compositions pharmaceutiques en contenant
EP0034473A2 (fr) * 1980-02-13 1981-08-26 Farmos-Yhtyma Oy Imidazoles substitués, procédés pour leur préparation et compositions pharmaceutiques les contenant
EP0034473A3 (en) * 1980-02-13 1981-11-18 Farmos-Yhtyma Oy Substituted imidazoles, their preparation, pharmaceutical compositions containing the same and their use in therapy
FR2613720A1 (fr) * 1987-04-10 1988-10-14 Esteve Labor Dr Derives d'aryl-heteroaryl carbinols avec activite analgesique
EP0289380A1 (fr) * 1987-04-10 1988-11-02 Laboratorios Del Dr. Esteve, S.A. Dérivés d'aryl-hétéroaryl carbinols avec activité analgésique
US5017596A (en) * 1987-04-10 1991-05-21 Laboratorios Del Dr. Esteve, S.A. Arylpyrazolylcarbinol compounds with analgesic activity

Also Published As

Publication number Publication date
FR2166117B1 (fr) 1977-01-28
AT330764B (de) 1976-07-26
CH615919A5 (fr) 1980-02-29
DE2164919C3 (de) 1980-04-10
CH615668A5 (fr) 1980-02-15
JPS4875575A (fr) 1973-10-11
NO137123B (no) 1977-09-26
US4213994A (en) 1980-07-22
BE793407A (fr) 1973-06-28
ES409907A1 (es) 1975-11-16
NO137123C (no) 1978-01-04
DE2164919B2 (de) 1979-08-09
CH615920A5 (fr) 1980-02-29
ZA729141B (en) 1973-09-26
GB1421774A (en) 1976-01-21
KR780000115B1 (en) 1978-04-15
IL41179A (en) 1978-06-15
IL41179A0 (en) 1973-02-28
SE412388B (sv) 1980-03-03
CA989845A (en) 1976-05-25
DE2164919A1 (de) 1973-07-12
ATA1107972A (de) 1975-10-15
NL7217517A (fr) 1973-07-02

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Legal Events

Date Code Title Description
CD Change of name or company name
ST Notification of lapse