FR2146943A1 - Thrombolytic enzyme - from streptomyces venetus - Google Patents

Thrombolytic enzyme - from streptomyces venetus

Info

Publication number
FR2146943A1
FR2146943A1 FR7127449A FR7127449A FR2146943A1 FR 2146943 A1 FR2146943 A1 FR 2146943A1 FR 7127449 A FR7127449 A FR 7127449A FR 7127449 A FR7127449 A FR 7127449A FR 2146943 A1 FR2146943 A1 FR 2146943A1
Authority
FR
France
Prior art keywords
venetus
streptomyces
thrombolytic enzyme
enzyme
thrombolytis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7127449A
Other languages
French (fr)
Other versions
FR2146943B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE786788D priority Critical patent/BE786788A/en
Application filed by Rhone Poulenc SA filed Critical Rhone Poulenc SA
Priority to FR7127449A priority patent/FR2146943A1/en
Priority to FR7221092A priority patent/FR2187293B2/fr
Priority to NL7209980A priority patent/NL7209980A/xx
Priority to IE1045/72A priority patent/IE36596B1/en
Priority to AU44965/72A priority patent/AU468851B2/en
Priority to HURO671A priority patent/HU164499B/hu
Priority to GB3482572A priority patent/GB1375478A/en
Priority to US275091A priority patent/US3875005A/en
Priority to SU1817741A priority patent/SU434662A3/en
Priority to ES0405205A priority patent/ES405205A1/en
Priority to SE7209791A priority patent/SE387957B/en
Priority to DK370372AA priority patent/DK131043B/en
Priority to CH1113872A priority patent/CH556388A/en
Priority to DE19722236772 priority patent/DE2236772A1/en
Priority to CA148,034A priority patent/CA981611A/en
Priority to AT646872A priority patent/AT313225B/en
Priority to AR243312A priority patent/AR194605A1/en
Publication of FR2146943A1 publication Critical patent/FR2146943A1/en
Application granted granted Critical
Publication of FR2146943B1 publication Critical patent/FR2146943B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

A novel thrombolytis enzyme, 22,750 RP, (I), is obtd. by incubating Streptomyces venetus DS 24288, or a mutant, in an aerated medium for 1-7 days at 23-30 degrees and pH 6.0-7.8. (I) is isolated, e.g., by filtering the broth, acidifying to pH 4 to ppte. unwanted material, dialysing, and ppting. with Me2CO, opt. followed by chromatography and/or electrophoresis.
FR7127449A 1971-07-27 1971-07-27 Thrombolytic enzyme - from streptomyces venetus Granted FR2146943A1 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
BE786788D BE786788A (en) 1971-07-27 NEW THROMBOLYTIC ENZYME AND ITS PREPARATION BY FERMENTATION OF A STREPTOMYCES
FR7127449A FR2146943A1 (en) 1971-07-27 1971-07-27 Thrombolytic enzyme - from streptomyces venetus
FR7221092A FR2187293B2 (en) 1971-07-27 1972-06-12
NL7209980A NL7209980A (en) 1971-07-27 1972-07-19
US275091A US3875005A (en) 1971-07-27 1972-07-25 Thrombolytic and fibrinolytic enzyme from streptomyces
AU44965/72A AU468851B2 (en) 1971-07-27 1972-07-25 Anew enzyme and compositions containing it
HURO671A HU164499B (en) 1971-07-27 1972-07-25
GB3482572A GB1375478A (en) 1971-07-27 1972-07-25
IE1045/72A IE36596B1 (en) 1971-07-27 1972-07-25 A new enzyme and compositions containing it
SU1817741A SU434662A3 (en) 1971-07-27 1972-07-25 METHOD OF OBTAINING FIBRINOLYTIC EXPERTS
SE7209791A SE387957B (en) 1971-07-27 1972-07-26 PROCEDURE FOR THE PRODUCTION OF AN ENZYMATIC SUBSTANCE DESIGNATED WITH NO 22750 RP BY CULTIVATION OF A NEW ORGANISM NAMED STREPTOMYCES VENETUS
DK370372AA DK131043B (en) 1971-07-27 1972-07-26 Process for the preparation of a proteolytic enzyme, designated 22750 RP.
CH1113872A CH556388A (en) 1971-07-27 1972-07-26 PROCESS FOR PREPARING A THROMBOLYTIC ENZYME.
DE19722236772 DE2236772A1 (en) 1971-07-27 1972-07-26 NEW THROMBOLYTIC ENZYME AND ITS PRODUCTION BY FERMENTATION OF A STREPTOMYCES
CA148,034A CA981611A (en) 1971-07-27 1972-07-26 Enzyme thrombolitique et sa preparation par fermentation de streptomyces venetus
ES0405205A ES405205A1 (en) 1971-07-27 1972-07-26 Procedure for the preparation of an enzymatic substance with thrombolic activity. (Machine-translation by Google Translate, not legally binding)
AT646872A AT313225B (en) 1971-07-27 1972-07-27 Process for the preparation of an enzymatic substance with thrombolytic activity
AR243312A AR194605A1 (en) 1971-07-27 1972-07-27 PROCEDURE FOR THE PREPARATION OF FIBRINOLYTIC ENZYME 22.750RP

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7127449A FR2146943A1 (en) 1971-07-27 1971-07-27 Thrombolytic enzyme - from streptomyces venetus

Publications (2)

Publication Number Publication Date
FR2146943A1 true FR2146943A1 (en) 1973-03-09
FR2146943B1 FR2146943B1 (en) 1974-09-06

Family

ID=9080984

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7127449A Granted FR2146943A1 (en) 1971-07-27 1971-07-27 Thrombolytic enzyme - from streptomyces venetus

Country Status (4)

Country Link
AU (1) AU468851B2 (en)
DE (1) DE2236772A1 (en)
FR (1) FR2146943A1 (en)
SU (1) SU434662A3 (en)

Also Published As

Publication number Publication date
AU4496572A (en) 1974-01-31
SU434662A3 (en) 1974-06-30
FR2146943B1 (en) 1974-09-06
AU468851B2 (en) 1976-01-22
DE2236772A1 (en) 1973-02-08

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Legal Events

Date Code Title Description
ST Notification of lapse