FR2132761A1 - Vasoactive substances produced by extracting from - ginkgo biloba leaves - Google Patents

Vasoactive substances produced by extracting from - ginkgo biloba leaves

Info

Publication number
FR2132761A1
FR2132761A1 FR7212288A FR7212288A FR2132761A1 FR 2132761 A1 FR2132761 A1 FR 2132761A1 FR 7212288 A FR7212288 A FR 7212288A FR 7212288 A FR7212288 A FR 7212288A FR 2132761 A1 FR2132761 A1 FR 2132761A1
Authority
FR
France
Prior art keywords
mek
extn
ext
alcohol
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7212288A
Other languages
English (en)
French (fr)
Other versions
FR2132761B1 (https=
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Willmar Schwabe GmbH and Co KG
Original Assignee
Dr Willmar Schwabe GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Willmar Schwabe GmbH and Co KG filed Critical Dr Willmar Schwabe GmbH and Co KG
Publication of FR2132761A1 publication Critical patent/FR2132761A1/fr
Application granted granted Critical
Publication of FR2132761B1 publication Critical patent/FR2132761B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)
FR7212288A 1971-04-08 1972-04-07 Vasoactive substances produced by extracting from - ginkgo biloba leaves Granted FR2132761A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2117429A DE2117429C3 (de) 1971-04-08 1971-04-08 Verfahren zur Herstellung eines Injektions- bzw. Infusionspräparates mit einem Gehalt an einem Wirkstoffgemisch aus den Blättern von Ginkgo biloba

Publications (2)

Publication Number Publication Date
FR2132761A1 true FR2132761A1 (en) 1972-11-24
FR2132761B1 FR2132761B1 (https=) 1975-10-10

Family

ID=5804351

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7212288A Granted FR2132761A1 (en) 1971-04-08 1972-04-07 Vasoactive substances produced by extracting from - ginkgo biloba leaves

Country Status (6)

Country Link
JP (1) JPS4927323B1 (https=)
BE (1) BE781802A (https=)
DE (1) DE2117429C3 (https=)
FR (1) FR2132761A1 (https=)
LU (1) LU65123A1 (https=)
NL (1) NL175383C (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2627387A1 (fr) * 1988-02-24 1989-08-25 Fabre Sa Pierre Procede d'obtention d'un extrait de feuilles de ginkgo biloba
EP0352146A1 (fr) 1988-07-19 1990-01-24 Abraxas Bio Labs S.A. Régulateur biologique extrait de Gingko Biloba, actif dans diverses pathologies.
EP0437840A1 (en) * 1989-12-29 1991-07-24 Freund Industrial Co., Ltd. Aqueous solution containing ginkgo-leaf extract
ES2036951A1 (es) * 1991-11-29 1993-06-01 Euromed S A Procedimiento de obtencion de un extracto esencialmente compuesto de ginkgoflavonoides a partir de las hojas de ginkgo biloba.

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50144535U (https=) * 1974-05-15 1975-11-28
FR2518406A1 (fr) * 1981-12-22 1983-06-24 Prodipharm Nouveau procede d'obtention de substances vaso-actives extraites de feuilles de ginkgo
GB8418424D0 (en) * 1984-07-19 1984-08-22 Scras Inhibition of platelets aggregation
JP2818220B2 (ja) * 1988-11-04 1998-10-30 フロイント産業株式会社 食品用の含水有機溶剤抽出物含有組成物および医薬用の含水有機溶剤抽出物含有組成物、並びにそれらの製造方法
KR940002795B1 (ko) * 1989-06-16 1994-04-02 주식회사 선경인더스트리 은행잎에서 징코라이드를 분리 및 정제하는 방법
DE3940092A1 (de) * 1989-12-04 1991-06-06 Schwabe Willmar Gmbh & Co Extrakt aus blaettern von ginkgo biloba, verfahren zu seiner herstellung und den extrakt enthaltende arzneimittel
DE3940094A1 (de) * 1989-12-04 1991-06-06 Montana Ltd Wirkstoffkonzentrate und neue wirkstoff-kombinationen aus blaettern von ginkgo biloba, ein verfahren zu ihrer herstellung und die wirkstoff-konzentrate bzw. die wirkstoff-kombinationen enthaltenden arzneimittel
DE3940091A1 (de) * 1989-12-04 1991-06-06 Schwabe Willmar Gmbh & Co Extrakt aus blaettern von ginkgo biloba, verfahren zu seiner herstellung und den extrakt enthaltende arzneimittel
DE4030758A1 (de) * 1990-09-28 1992-04-02 Schwabe Willmar Gmbh & Co Extrakt aus blaettern von ginkgo biloba, insbesondere zur intravenoesen injektion oder infusion, verfahren zu seiner herstellung und den extrakt enthaltende ampullenpraeparate
US6086883A (en) * 1993-12-03 2000-07-11 Montana Limited Extract from the leaves of Ginkgo biloba
DE19829516B4 (de) † 1998-07-02 2004-08-26 Dr. Willmar Schwabe Gmbh & Co. Kg Wasserlöslicher nativer Trockenextrakt aus Gingko biloba mit hohem Gehalt an Terpenoiden und Flavonglykosiden
DE10040610A1 (de) * 2000-08-16 2002-03-07 Schwabe Willmar Gmbh & Co Flavonhaltige Pflanzenextraktlösungen mit verbesserter Lager- und Hitzestabilität
US6590109B2 (en) * 2001-07-11 2003-07-08 The Trustees Of Columbia University In The City Of New York Method for isolating terpene trilactones (ginkgolides, bilobalide) from leaves and pharmaceutical powders of ginkgo biloba
WO2003082185A2 (en) 2002-03-29 2003-10-09 The Trustees Of Columbia University In The City Of New York Analogs of terpene trilactones from ginkgo biloba and related compounds and uses thereof
US7429670B2 (en) 2003-08-27 2008-09-30 The Trustees Of Columbia University In The City Of New York Synthesis of derivatives of ginkgolide C
WO2005046829A2 (en) 2003-11-12 2005-05-26 The Trustees Of Columbia University In The City Of New York Separation of ginkgolides and bilobalide from g. biloba
CN1954826A (zh) 2005-10-26 2007-05-02 上海生物芯片有限公司 银杏叶提取物在降低胆固醇方面的用途
CN102659808B (zh) 2012-04-23 2014-10-29 成都百裕科技制药有限公司 一种银杏内酯的提取分离方法
DE102023131617A1 (de) 2023-11-14 2025-05-15 Dr. Willmar Schwabe Gmbh & Co. Kg Verfahren zur Herstellung von Ginkgoextrakten mit hohem Gehalt an Proanthocyanidinen und Nahrungsergänzungsmittel und Arzneimittel enthaltend Ginkgoextrakte

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1418062A (fr) * 1964-07-10 1965-11-19 Organon Nv Purification de préparation biologiquement actives de source animale

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1767098C2 (de) * 1968-03-29 1973-01-04 Dr. Willmar Schwabe Gmbh, 7500 Karlsruhe-Durlach Verfahren zur Gewinnung eines vasoaktiven Arzneimittels aus den Blättern von Ginkgo biloba

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1418062A (fr) * 1964-07-10 1965-11-19 Organon Nv Purification de préparation biologiquement actives de source animale

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2627387A1 (fr) * 1988-02-24 1989-08-25 Fabre Sa Pierre Procede d'obtention d'un extrait de feuilles de ginkgo biloba
EP0330567A1 (fr) * 1988-02-24 1989-08-30 Pierre Fabre Sante Procédé d'obtention d'un extrait de feuilles de ginkgo biloba
US4981688A (en) * 1988-02-24 1991-01-01 Pierre Fabre Medicament Method for obtaining an extract or Ginkgo biloba leaves
EP0352146A1 (fr) 1988-07-19 1990-01-24 Abraxas Bio Labs S.A. Régulateur biologique extrait de Gingko Biloba, actif dans diverses pathologies.
FR2634380A1 (fr) * 1988-07-19 1990-01-26 Beljanski Mirko Regulateur biologique, actif dans diverses pathologies
EP0437840A1 (en) * 1989-12-29 1991-07-24 Freund Industrial Co., Ltd. Aqueous solution containing ginkgo-leaf extract
ES2036951A1 (es) * 1991-11-29 1993-06-01 Euromed S A Procedimiento de obtencion de un extracto esencialmente compuesto de ginkgoflavonoides a partir de las hojas de ginkgo biloba.

Also Published As

Publication number Publication date
DE2117429A1 (de) 1972-10-12
LU65123A1 (https=) 1972-07-12
DE2117429B2 (de) 1981-05-27
FR2132761B1 (https=) 1975-10-10
NL175383C (nl) 1984-11-01
NL7204696A (https=) 1972-10-10
DE2117429C3 (de) 1982-04-01
NL175383B (nl) 1984-06-01
JPS4927323B1 (https=) 1974-07-17
BE781802A (fr) 1972-07-31

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Legal Events

Date Code Title Description
CL Concession to grant licences
CL Concession to grant licences
EM Correction of a material error concerning inscription in the national patent register
CA Change of address
CD Change of name or company name
CL Concession to grant licences
CL Concession to grant licences