US5846782A
(en)
|
1995-11-28 |
1998-12-08 |
Genvec, Inc. |
Targeting adenovirus with use of constrained peptide motifs
|
US6465253B1
(en)
|
1994-09-08 |
2002-10-15 |
Genvec, Inc. |
Vectors and methods for gene transfer to cells
|
US5770442A
(en)
*
|
1995-02-21 |
1998-06-23 |
Cornell Research Foundation, Inc. |
Chimeric adenoviral fiber protein and methods of using same
|
US6127525A
(en)
*
|
1995-02-21 |
2000-10-03 |
Cornell Research Foundation, Inc. |
Chimeric adenoviral coat protein and methods of using same
|
EP1445322B2
(en)
|
1995-06-15 |
2012-06-06 |
Crucell Holland B.V. |
Packaging systems for human recombinant adenovirus to be used in gene therapy
|
CA2277869A1
(en)
*
|
1997-01-17 |
1998-07-23 |
Institut National De La Sante Et De La Recherche Medicale |
Adenoviral-vector-mediated gene transfer into medullary motor neurons
|
FR2761258B1
(fr)
*
|
1997-03-26 |
1999-06-11 |
Rhone Poulenc Rorer Sa |
Procede de stimulation de la regeneration nerveuse
|
US20030017138A1
(en)
|
1998-07-08 |
2003-01-23 |
Menzo Havenga |
Chimeric adenoviruses
|
US6929946B1
(en)
|
1998-11-20 |
2005-08-16 |
Crucell Holland B.V. |
Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells
|
US6913922B1
(en)
*
|
1999-05-18 |
2005-07-05 |
Crucell Holland B.V. |
Serotype of adenovirus and uses thereof
|
US6492169B1
(en)
|
1999-05-18 |
2002-12-10 |
Crucell Holland, B.V. |
Complementing cell lines
|
US20050232900A1
(en)
*
|
1999-05-18 |
2005-10-20 |
Crucell Holland B.V. |
Serotype of adenovirus and uses thereof
|
WO2001036603A2
(en)
*
|
1999-11-17 |
2001-05-25 |
Avigen, Inc. |
Recombinant adeno-associated virus virions for the treatment of lysosomal disorders
|
US7235233B2
(en)
|
2000-09-26 |
2007-06-26 |
Crucell Holland B.V. |
Serotype 5 adenoviral vectors with chimeric fibers for gene delivery in skeletal muscle cells or myoblasts
|
US6998118B2
(en)
*
|
2001-12-21 |
2006-02-14 |
The Salk Institute For Biological Studies |
Targeted retrograde gene delivery for neuronal protection
|
CA2471812C
(en)
*
|
2001-12-21 |
2012-09-04 |
The Salk Institute For Biological Studies |
Targeted retrograde gene delivery to motor neurons
|
MXPA04008891A
(es)
*
|
2002-04-25 |
2004-11-26 |
Crucell Holland Bv |
Medios y metodos para la produccion de vectores de adenovirus.
|
HUE030903T2
(en)
|
2006-04-25 |
2017-06-28 |
Univ California |
Administration of growth factors for the treatment of CNS disorders
|
ES2560107T3
(es)
|
2009-02-12 |
2016-02-17 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con el factor neurotrófico derivado de cerebro (BDNF) por inhibición de transcrito antisentido natural para BDNF
|
US20110319476A1
(en)
|
2009-02-12 |
2011-12-29 |
Opko Curna, Llc |
Treatment of glial cell derived neurotrophic factor (gdnf) related diseases by inhibition of natural antisense transcript to gdnf
|
US20110319317A1
(en)
|
2009-03-04 |
2011-12-29 |
Opko Curna, Llc |
Treatment of sirtuin 1 (sirt1) related diseases by inhibition of natural antisense transcript to sirt1
|
WO2010107733A2
(en)
|
2009-03-16 |
2010-09-23 |
Curna, Inc. |
Treatment of nuclear factor (erythroid-derived 2)-like 2 (nrf2) related diseases by inhibition of natural antisense transcript to nrf2
|
EP2408920B1
(en)
|
2009-03-17 |
2017-03-08 |
CuRNA, Inc. |
Treatment of delta-like 1 homolog (dlk1) related diseases by inhibition of natural antisense transcript to dlk1
|
JP6250930B2
(ja)
|
2009-05-06 |
2017-12-20 |
クルナ・インコーポレーテッド |
トリステトラプロリン(ttp)に対する天然アンチセンス転写物の抑制によるttp関連疾患の治療
|
US9155754B2
(en)
|
2009-05-06 |
2015-10-13 |
Curna, Inc. |
Treatment of ABCA1 gene related diseases by inhibition of a natural antisense transcript to ABCA1
|
CA2762369C
(en)
|
2009-05-18 |
2021-12-28 |
Joseph Collard |
Treatment of reprogramming factor related diseases by inhibition of natural antisense transcript to a reprogramming factor
|
KR101703695B1
(ko)
|
2009-05-22 |
2017-02-08 |
큐알엔에이, 인크. |
전사 인자 e3(tfe3)에 대한 천연 안티센스 전사체의 억제에 의해 tfe3 및 인슐린 수용체 기질 2(irs2)의 치료
|
CA2764683A1
(en)
|
2009-05-28 |
2010-12-02 |
Joseph Collard |
Treatment of antiviral gene related diseases by inhibition of natural antisense transcript to an antiviral gene
|
EP2443238B1
(en)
|
2009-06-16 |
2017-03-22 |
CuRNA, Inc. |
Treatment of paraoxonase 1 (pon1) related diseases by inhibition of natural antisense transcript to pon1
|
EP2443237B1
(en)
|
2009-06-16 |
2017-02-22 |
CuRNA, Inc. |
Treatment of collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene
|
EP2446036B1
(en)
|
2009-06-24 |
2017-03-01 |
CuRNA, Inc. |
Treatment of tumor necrosis factor receptor 2 (tnfr2) related diseases by inhibition of natural antisense transcript to tnfr2
|
JP5907866B2
(ja)
|
2009-06-26 |
2016-04-26 |
クルナ・インコーポレーテッド |
ダウン症候群遺伝子に対する天然アンチセンス転写物の抑制によるダウン症候群遺伝子関連疾患の治療
|
US9234199B2
(en)
|
2009-08-05 |
2016-01-12 |
Curna, Inc. |
Treatment of insulin gene (INS) related diseases by inhibition of natural antisense transcript to an insulin gene (INS)
|
CA2771172C
(en)
|
2009-08-25 |
2021-11-30 |
Opko Curna, Llc |
Treatment of 'iq motif containing gtpase activating protein' (iqgap) related diseases by inhibition of natural antisense transcript to iqgap
|
EP2513310B1
(en)
|
2009-12-16 |
2017-11-01 |
CuRNA, Inc. |
Treatment of membrane bound transcription factor peptidase, site 1 (mbtps1) related diseases by inhibition of natural antisense transcript to mbtps1
|
KR101891352B1
(ko)
|
2009-12-23 |
2018-08-24 |
큐알엔에이, 인크. |
간세포 성장 인자(hgf)에 대한 천연 안티센스 전사체의 억제에 의한 hgf 관련 질환의 치료
|
US9068183B2
(en)
|
2009-12-23 |
2015-06-30 |
Curna, Inc. |
Treatment of uncoupling protein 2 (UCP2) related diseases by inhibition of natural antisense transcript to UCP2
|
JP5982288B2
(ja)
|
2009-12-29 |
2016-08-31 |
カッパーアールエヌエー,インコーポレイテッド |
腫瘍タンパク質63(p63)に対する天然アンチセンス転写物の阻害による腫瘍タンパク質63関連疾患の治療
|
CN102782134B
(zh)
|
2009-12-29 |
2017-11-24 |
库尔纳公司 |
通过抑制核呼吸因子1(nrf1)的天然反义转录物而治疗nrf1相关疾病
|
WO2011082409A2
(en)
|
2010-01-04 |
2011-07-07 |
Curna, Inc. |
Treatment of interferon regulatory factor 8 (irf8) related diseases by inhibition of natural antisense transcript to irf8
|
JP5963680B2
(ja)
|
2010-01-06 |
2016-08-03 |
カッパーアールエヌエー,インコーポレイテッド |
膵臓発生遺伝子に対する天然アンチセンス転写物の阻害による膵臓発生遺伝子疾患の治療
|
DK2524039T3
(en)
|
2010-01-11 |
2018-03-12 |
Curna Inc |
TREATMENT OF GENDER HORMON-BINDING GLOBULIN (SHBG) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENCE TRANSCRIPTS TO SHBG
|
WO2011091390A2
(en)
|
2010-01-25 |
2011-07-28 |
Opko Curna, Llc |
Treatment of rnase h1 related diseases by inhibition of natural antisense transcript to rnase h1
|
KR101838308B1
(ko)
|
2010-02-22 |
2018-03-13 |
큐알엔에이, 인크. |
피롤린-5-카르복실레이트 환원효소 1(pycr1)에 대한 천연 안티센스 전사체의 억제에 의한 pycr1과 관련된 질환의 치료
|
CN102858979B
(zh)
|
2010-04-09 |
2018-01-26 |
库尔纳公司 |
通过抑制成纤维细胞生长因子21(fgf21)的天然反义转录物而治疗fgf21相关疾病
|
RU2693462C2
(ru)
|
2010-05-03 |
2019-07-03 |
Курна, Инк. |
Лечение заболеваний, связанных с сиртуином (sirt), путем ингибирования природного антисмыслового транскрипта к сиртуину (sirt)
|
TWI531370B
(zh)
|
2010-05-14 |
2016-05-01 |
可娜公司 |
藉由抑制par4天然反股轉錄本治療par4相關疾病
|
NO2576783T3
(sv)
|
2010-05-26 |
2018-04-28 |
|
|
JP5998131B2
(ja)
|
2010-07-14 |
2016-09-28 |
カッパーアールエヌエー,インコーポレイテッド |
Discslargehomolog(dlg)dlg1への天然アンチセンス転写物の阻害によるdlg関連疾患の治療
|
ES2640755T3
(es)
|
2010-10-06 |
2017-11-06 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con la Sialidasa 4 (neu4) mediante inhibición del transcrito antisentido natural al gen neu4
|
CN103180445B
(zh)
|
2010-10-22 |
2018-02-16 |
库尔纳公司 |
通过抑制α‑L‑艾杜糖醛酸酶(IDUA)的天然反义转录物而治疗IDUA相关疾病
|
CA2816056A1
(en)
|
2010-10-27 |
2012-05-03 |
Curna, Inc. |
Treatment of interferon-related developmental regulator 1 (ifrd1) related diseases by inhibition of natural antisense transcript to ifrd1
|
CA2818824A1
(en)
|
2010-11-23 |
2012-05-31 |
Joseph Collard |
Treatment of nanog related diseases by inhibition of natural antisense transcript to nanog
|
CA2838588C
(en)
|
2011-06-09 |
2021-09-14 |
Curna, Inc. |
Treatment of frataxin (fxn) related diseases by inhibition of natural antisense transcript to fxn
|
EP2825648B1
(en)
|
2012-03-15 |
2018-09-05 |
CuRNA, Inc. |
Treatment of brain derived neurotrophic factor (bdnf) related diseases by inhibition of natural antisense transcript to bdnf
|
WO2015171918A2
(en)
|
2014-05-07 |
2015-11-12 |
Louisiana State University And Agricultural And Mechanical College |
Compositions and uses for treatment thereof
|
GB201410693D0
(en)
|
2014-06-16 |
2014-07-30 |
Univ Southampton |
Splicing modulation
|
CN107109411B
(zh)
|
2014-10-03 |
2022-07-01 |
冷泉港实验室 |
核基因输出的定向增加
|
IL308174A
(en)
|
2015-10-09 |
2024-01-01 |
Univ Southampton |
Gene expression modulation and dysregulated protein expression scanning
|
EP3390642B1
(en)
|
2015-12-14 |
2021-11-24 |
Cold Spring Harbor Laboratory |
Compositions for treatment of retinitis pigmentosa 13
|
CA3005246A1
(en)
|
2015-12-14 |
2017-06-22 |
Cold Spring Harbor Laboratory |
Compositions and methods for treatment of central nervous system diseases
|
US11096956B2
(en)
|
2015-12-14 |
2021-08-24 |
Stoke Therapeutics, Inc. |
Antisense oligomers and uses thereof
|
EP3389671A4
(en)
|
2015-12-14 |
2019-07-17 |
Cold Spring Harbor Laboratory |
ANTISENSE OLIGOMERS FOR THE TREATMENT OF ALAGILLE'S SYNDROME
|
WO2017106283A1
(en)
|
2015-12-14 |
2017-06-22 |
Cold Spring Harbor Laboratory |
Compositions and methods for treatment of liver diseases
|
CA3005256A1
(en)
|
2015-12-14 |
2017-06-22 |
Cold Spring Harbor Laboratory |
Antisense oligomers for treatment of autosomal dominant mental retardation-5 and dravet syndrome
|
HUE064635T2
(hu)
|
2017-08-25 |
2024-04-28 |
Stoke Therapeutics Inc |
Antisensz oligomerek állapotok és betegségek kezelésére
|
GB2610100B
(en)
|
2017-10-23 |
2023-08-16 |
Stoke Therapeutics Inc |
Antisense oligomers for treatment of non-sense mediated RNA decay based conditions and diseases
|
EP3788169A4
(en)
|
2018-05-04 |
2022-08-10 |
Stoke Therapeutics, Inc. |
METHODS AND COMPOSITIONS FOR TREATING A CHOLESTERYL ESTER STORAGE DISEASE
|
US11845797B2
(en)
|
2018-07-03 |
2023-12-19 |
Marengo Therapeutics, Inc. |
Anti-TCR antibody molecules and uses thereof
|
TW202208627A
(zh)
|
2020-05-11 |
2022-03-01 |
美商斯托克治療公司 |
用於病症及疾病之治療的opa1反義寡聚物
|
AU2022255506A1
(en)
|
2021-04-08 |
2023-11-09 |
Marengo Therapeutics, Inc. |
Multifunctional molecules binding to tcr and uses thereof
|
US20240209371A1
(en)
|
2021-04-22 |
2024-06-27 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating cancer
|
WO2023178311A1
(en)
*
|
2022-03-18 |
2023-09-21 |
The University Of North Carolina At Chapel Hill |
Methods for treating disorders under hypothermia and compositions relating to the same
|