FI960309A0 - Neisseria meningitidis, B-ryhmän ulkomembraanin poriiniproteiinien korkean tason ilmentäminen, puhdistaminen ja uudelleenlaskostaminen - Google Patents

Neisseria meningitidis, B-ryhmän ulkomembraanin poriiniproteiinien korkean tason ilmentäminen, puhdistaminen ja uudelleenlaskostaminen

Info

Publication number
FI960309A0
FI960309A0 FI960309A FI960309A FI960309A0 FI 960309 A0 FI960309 A0 FI 960309A0 FI 960309 A FI960309 A FI 960309A FI 960309 A FI960309 A FI 960309A FI 960309 A0 FI960309 A0 FI 960309A0
Authority
FI
Finland
Prior art keywords
refolding
purification
group
neisseria meningitidis
level expression
Prior art date
Application number
FI960309A
Other languages
English (en)
Swedish (sv)
Other versions
FI960309A (fi
Inventor
Milan S Blake
Joseph Y Tai
Huilin L Qi
Shu-Mei Liang
Lucjan J J Hronowski
Jeffrey K Pullen
Original Assignee
Univ Rockefeller
North American Vaccine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rockefeller, North American Vaccine Inc filed Critical Univ Rockefeller
Publication of FI960309A0 publication Critical patent/FI960309A0/fi
Publication of FI960309A publication Critical patent/FI960309A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
FI960309A 1993-07-23 1996-01-23 Neisseria meningitidis, B-ryhmän ulkomembraanin poriiniproteiinien korkean tason ilmentäminen, puhdistaminen ja uudelleenlaskostaminen FI960309A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/096,182 US5439808A (en) 1993-07-23 1993-07-23 Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
PCT/US1994/008327 WO1995003413A1 (en) 1993-07-23 1994-07-22 High level expression, purification and refolding of the neisseria meningitidis outer membrane group b porin proteins

Publications (2)

Publication Number Publication Date
FI960309A0 true FI960309A0 (fi) 1996-01-23
FI960309A FI960309A (fi) 1996-03-22

Family

ID=22256136

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960309A FI960309A (fi) 1993-07-23 1996-01-23 Neisseria meningitidis, B-ryhmän ulkomembraanin poriiniproteiinien korkean tason ilmentäminen, puhdistaminen ja uudelleenlaskostaminen

Country Status (12)

Country Link
US (3) US5439808A (fi)
EP (1) EP0713530A4 (fi)
JP (1) JPH09500538A (fi)
AU (1) AU690570B2 (fi)
BR (1) BR9407092A (fi)
CA (1) CA2167677A1 (fi)
FI (1) FI960309A (fi)
NO (1) NO960256L (fi)
NZ (1) NZ269996A (fi)
PL (1) PL182573B1 (fi)
RU (1) RU2181378C2 (fi)
WO (1) WO1995003413A1 (fi)

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US6284884B1 (en) 1995-06-07 2001-09-04 North American Vaccine, Inc. Antigenic group B streptococcus type II and type III polysaccharide fragments having a 2,5-anhydro-D-mannose terminal structure and conjugate vaccine thereof
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US6482415B1 (en) * 1997-12-24 2002-11-19 The United States Of America As Represented By The Secretary Of The Navy Expression and refolding of truncated recombinant major outer membrane protein antigen (r56) of Orientia tsutsugamushi and its use in antibody based detection assays and vaccines
US7335477B2 (en) * 1997-12-24 2008-02-26 The United States Of America As Represented By The Secretary Of The Navy Truncated recombinant major outer membrane protein antigen (r56) of Orientia tsutsugamushi strains Karp, Kato and Gilliam and its use in antibody based detection assays and vaccines
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US20110045011A1 (en) * 1998-12-22 2011-02-24 Wei-Mei Ching TRUNCATED RECOMBINANT MAJOR OUTER MEMBRANE PROTEIN ANTIGEN (R56) OF ORIENTIA TSUTSUGAMUSHI STRAINS KARP, KATO and GILLIAM AND ITS USE IN ANTIBODY BASED DETECTION ASSAYS AND VACCINES
EP1154791B1 (en) 1999-02-22 2008-02-20 Health Protection Agency Neisserial vaccine compositions and methods
US7081244B2 (en) * 1999-02-22 2006-07-25 Health Protection Agency Neisserial vaccine compositions and methods
EP1228217B1 (en) 1999-04-30 2012-11-21 Novartis Vaccines and Diagnostics S.r.l. Conserved neisserial antigens
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US20070020293A1 (en) 2003-06-23 2007-01-25 Michon Francis J Vaccines against group neisseria meningitidis and meningococcal combinations thereof
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PT2682126T (pt) 2005-01-27 2017-02-28 Children`S Hospital & Res Center At Oakland Vacinas de vesícula com base em agn1870 para proteção de amplo espetro contra doenças causadas por neisseria meningitidis
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Also Published As

Publication number Publication date
US5879686A (en) 1999-03-09
AU7371694A (en) 1995-02-20
PL182573B1 (pl) 2002-01-31
JPH09500538A (ja) 1997-01-21
NO960256D0 (no) 1996-01-22
NO960256L (no) 1996-03-20
WO1995003413A1 (en) 1995-02-02
RU2181378C2 (ru) 2002-04-20
BR9407092A (pt) 1996-09-03
US6013267A (en) 2000-01-11
US5439808A (en) 1995-08-08
NZ269996A (en) 1997-10-24
PL312712A1 (en) 1996-05-13
AU690570B2 (en) 1998-04-30
FI960309A (fi) 1996-03-22
EP0713530A1 (en) 1996-05-29
EP0713530A4 (en) 2002-09-18
CA2167677A1 (en) 1995-02-02

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