FI955438L - N-asyylisulfamidihappoesterit (tai -tioesterit), N-asyylisulfonamidit ja N-sulfonyylikarbamiinihappoesterit (tai -tioesterit) hyperkolesteroleemisina aineina - Google Patents

N-asyylisulfamidihappoesterit (tai -tioesterit), N-asyylisulfonamidit ja N-sulfonyylikarbamiinihappoesterit (tai -tioesterit) hyperkolesteroleemisina aineina Download PDF

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Publication number
FI955438L
FI955438L FI955438A FI955438A FI955438L FI 955438 L FI955438 L FI 955438L FI 955438 A FI955438 A FI 955438A FI 955438 A FI955438 A FI 955438A FI 955438 L FI955438 L FI 955438L
Authority
FI
Finland
Prior art keywords
thioesters
acid esters
acyl
sulfonamides
carbamic acid
Prior art date
Application number
FI955438A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI955438A0 (fi
FI955438A7 (fi
Inventor
Helen Tsenwhei Lee
Joseph Armand Picard
Drago Robert Sliskovic
Wendell Wierenga
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/223,932 external-priority patent/US5491172A/en
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of FI955438A0 publication Critical patent/FI955438A0/fi
Publication of FI955438A7 publication Critical patent/FI955438A7/fi
Publication of FI955438L publication Critical patent/FI955438L/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/02—Monoamides of sulfuric acids or esters thereof, e.g. sulfamic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/51—Y being a hydrogen or a carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
FI955438A 1993-05-14 1994-05-11 N-asyylisulfamidihappoesterit (tai -tioesterit), N-asyylisulfonamidit ja N-sulfonyylikarbamiinihappoesterit (tai -tioesterit) hyperkolesteroleemisina aineina FI955438L (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6251593A 1993-05-14 1993-05-14
US08/223,932 US5491172A (en) 1993-05-14 1994-04-13 N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
PCT/US1994/005233 WO1994026702A1 (en) 1993-05-14 1994-05-11 N-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents

Publications (3)

Publication Number Publication Date
FI955438A0 FI955438A0 (fi) 1995-11-10
FI955438A7 FI955438A7 (fi) 1995-11-10
FI955438L true FI955438L (fi) 1995-11-10

Family

ID=26742358

Family Applications (1)

Application Number Title Priority Date Filing Date
FI955438A FI955438L (fi) 1993-05-14 1994-05-11 N-asyylisulfamidihappoesterit (tai -tioesterit), N-asyylisulfonamidit ja N-sulfonyylikarbamiinihappoesterit (tai -tioesterit) hyperkolesteroleemisina aineina

Country Status (21)

Country Link
US (1) US5633287A (cs)
EP (1) EP0698010B1 (cs)
JP (1) JP3704149B2 (cs)
AT (1) ATE178891T1 (cs)
AU (1) AU681152B2 (cs)
CA (1) CA2158268C (cs)
CZ (1) CZ290683B6 (cs)
DE (1) DE69417885T2 (cs)
DK (1) DK0698010T3 (cs)
ES (1) ES2133163T3 (cs)
FI (1) FI955438L (cs)
GR (1) GR3030356T3 (cs)
HU (1) HU223044B1 (cs)
IL (1) IL109431A (cs)
NO (1) NO305861B1 (cs)
NZ (1) NZ266689A (cs)
PH (1) PH30943A (cs)
RU (1) RU2137756C1 (cs)
SG (1) SG47056A1 (cs)
SK (1) SK282790B6 (cs)
WO (1) WO1994026702A1 (cs)

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Also Published As

Publication number Publication date
AU6831194A (en) 1994-12-12
IL109431A (en) 2001-01-11
GR3030356T3 (en) 1999-09-30
FI955438A0 (fi) 1995-11-10
EP0698010B1 (en) 1999-04-14
SG47056A1 (en) 1998-03-20
FI955438A7 (fi) 1995-11-10
SK139695A3 (en) 1996-11-06
DE69417885D1 (de) 1999-05-20
ATE178891T1 (de) 1999-04-15
WO1994026702A1 (en) 1994-11-24
CZ296695A3 (en) 1996-09-11
RU2137756C1 (ru) 1999-09-20
DK0698010T3 (da) 1999-10-25
NZ266689A (en) 1997-11-24
DE69417885T2 (de) 1999-09-30
HU9502811D0 (en) 1995-11-28
NO954564L (no) 1996-01-11
US5633287A (en) 1997-05-27
PH30943A (en) 1997-12-23
CA2158268C (en) 2006-11-07
SK282790B6 (sk) 2002-12-03
CZ290683B6 (cs) 2002-09-11
NO954564D0 (no) 1995-11-13
NO305861B1 (no) 1999-08-09
ES2133163T3 (es) 1999-09-01
EP0698010A1 (en) 1996-02-28
HUT72653A (en) 1996-05-28
AU681152B2 (en) 1997-08-21
HU223044B1 (hu) 2004-03-01
IL109431A0 (en) 1994-07-31
CA2158268A1 (en) 1994-11-24
JPH08510256A (ja) 1996-10-29
JP3704149B2 (ja) 2005-10-05

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