FI951386A0 - Sulfanamidokarbonyylipyridiini-2-karboksyylihappoamidit sekä niiden pyridiini-N-oksidit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä - Google Patents

Sulfanamidokarbonyylipyridiini-2-karboksyylihappoamidit sekä niiden pyridiini-N-oksidit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä

Info

Publication number
FI951386A0
FI951386A0 FI951386A FI951386A FI951386A0 FI 951386 A0 FI951386 A0 FI 951386A0 FI 951386 A FI951386 A FI 951386A FI 951386 A FI951386 A FI 951386A FI 951386 A0 FI951386 A0 FI 951386A0
Authority
FI
Finland
Prior art keywords
alkyl
opt
bond
substd
alkoxy
Prior art date
Application number
FI951386A
Other languages
English (en)
Swedish (sv)
Other versions
FI951386A (fi
Inventor
Klaus Weidmann
Martin Bickel
Volkmar Guenzler-Pukall
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI951386A0 publication Critical patent/FI951386A0/fi
Publication of FI951386A publication Critical patent/FI951386A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
FI951386A 1994-03-25 1995-03-23 Sulfanamidokarbonyylipyridiini-2-karboksyylihappoamidit sekä niiden pyridiini-N-oksidit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä FI951386A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4410423A DE4410423A1 (de) 1994-03-25 1994-03-25 Sulfonamidocarbonylpyridin-2-carbonsäureamide sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (2)

Publication Number Publication Date
FI951386A0 true FI951386A0 (fi) 1995-03-23
FI951386A FI951386A (fi) 1995-09-26

Family

ID=6513863

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951386A FI951386A (fi) 1994-03-25 1995-03-23 Sulfanamidokarbonyylipyridiini-2-karboksyylihappoamidit sekä niiden pyridiini-N-oksidit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä

Country Status (20)

Country Link
US (1) US5610172A (fi)
EP (1) EP0673931B1 (fi)
JP (1) JPH07278109A (fi)
KR (1) KR950032124A (fi)
CN (1) CN1114312A (fi)
AT (1) ATE156815T1 (fi)
AU (1) AU689199B2 (fi)
CA (1) CA2145476A1 (fi)
CZ (1) CZ287768B6 (fi)
DE (2) DE4410423A1 (fi)
DK (1) DK0673931T3 (fi)
ES (1) ES2105798T3 (fi)
FI (1) FI951386A (fi)
GR (1) GR3024860T3 (fi)
HK (1) HK1012338A1 (fi)
HU (1) HUT72059A (fi)
NO (1) NO304308B1 (fi)
NZ (1) NZ270783A (fi)
PL (1) PL180042B1 (fi)
ZA (1) ZA952408B (fi)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
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US6191368B1 (en) 1995-09-12 2001-02-20 Tessera, Inc. Flexible, releasable strip leads
CN102526044A (zh) 2001-12-06 2012-07-04 法布罗根股份有限公司 提高内源性红细胞生成素(epo)的方法
EP2295060B1 (en) 2001-12-06 2018-10-31 Fibrogen, Inc. Treatment or prevention of ischemic or hypoxic conditions
US20040158289A1 (en) * 2002-11-30 2004-08-12 Girouard Steven D. Method and apparatus for cell and electrical therapy of living tissue
US8124582B2 (en) 2002-12-06 2012-02-28 Fibrogen, Inc. Treatment of diabetes
US7618940B2 (en) * 2002-12-06 2009-11-17 Fibrogen, Inc. Fat regulation
US8614204B2 (en) 2003-06-06 2013-12-24 Fibrogen, Inc. Enhanced erythropoiesis and iron metabolism
US7840263B2 (en) * 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
US7764995B2 (en) * 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7729761B2 (en) * 2004-07-14 2010-06-01 Cardiac Pacemakers, Inc. Method and apparatus for controlled gene or protein delivery
US7828711B2 (en) * 2004-08-16 2010-11-09 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular growth and regeneration using ventricular assist device
US8060219B2 (en) * 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
MX2007016160A (es) 2005-06-15 2008-03-07 Fibrogen Inc Uso de moduladoers de hif-1 alfa para el tratamiento contra el cancer.
US7774057B2 (en) 2005-09-06 2010-08-10 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression for cardiac protection
AU2007232607B2 (en) * 2006-03-30 2010-09-16 Lg Electronics Inc. A method and apparatus for decoding/encoding a video signal
EP2044005B8 (en) 2006-06-26 2012-12-05 Warner Chilcott Company, LLC Prolyl hydroxylase inhibitors and methods of use
WO2009002533A1 (en) * 2007-06-27 2008-12-31 The Brigham And Women's Hospital, Inc. Inflammatory bowel disease therapies
NO2686520T3 (fi) 2011-06-06 2018-03-17
EP3007695B1 (en) 2013-06-13 2024-02-07 Akebia Therapeutics, Inc. Compositions and methods for treating anemia
MA39033A1 (fr) 2013-11-15 2017-11-30 Akebia Therapeutics Inc Formes solides d'acide {[5-(3-chlorophényl)-3-hydroxypyridine-2-carbonyl] amino}acétique, compositions et leurs utilisations
BR112017015852A2 (pt) 2015-01-23 2018-03-27 Akebia Therapeutics Inc forma de cristal, sal hemicálcico, sal hemicálcico di-hidratado, sal monossódico hidratado, sal bissódico monoidratado, sal monossódico anidro e método para preparar o composto 1
DK3277270T3 (da) 2015-04-01 2021-12-06 Akebia Therapeutics Inc Sammensætninger og fremgangsmåder til behandling af anæmi
US11713298B2 (en) 2018-05-09 2023-08-01 Akebia Therapeutics, Inc. Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW352384B (en) * 1992-03-24 1999-02-11 Hoechst Ag Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals

Also Published As

Publication number Publication date
CZ287768B6 (en) 2001-01-17
ZA952408B (en) 1995-11-27
HUT72059A (en) 1996-03-28
EP0673931A1 (de) 1995-09-27
CA2145476A1 (en) 1995-09-26
DE4410423A1 (de) 1995-09-28
PL307848A1 (en) 1995-10-02
CZ73395A3 (en) 1995-11-15
PL180042B1 (en) 2000-12-29
ATE156815T1 (de) 1997-08-15
EP0673931B1 (de) 1997-08-13
HU9500865D0 (en) 1995-05-29
DK0673931T3 (da) 1998-03-16
US5610172A (en) 1997-03-11
AU689199B2 (en) 1998-03-26
KR950032124A (ko) 1995-12-20
NO951146L (no) 1995-09-26
ES2105798T3 (es) 1997-10-16
DE59500488D1 (de) 1997-09-18
JPH07278109A (ja) 1995-10-24
HK1012338A1 (en) 1999-07-30
AU1504295A (en) 1995-10-05
NO951146D0 (no) 1995-03-24
NO304308B1 (no) 1998-11-30
FI951386A (fi) 1995-09-26
CN1114312A (zh) 1996-01-03
GR3024860T3 (en) 1998-01-30
NZ270783A (en) 1997-02-24

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