US5354844A
(en)
*
|
1989-03-16 |
1994-10-11 |
Boehringer Ingelheim International Gmbh |
Protein-polycation conjugates
|
US5981273A
(en)
*
|
1991-09-30 |
1999-11-09 |
Boehringer Ingelheim Int'l. Gmbh |
Composition comprising an endosomolytic agent for introducing nucleic acid complexes into higher eucaryotic cells
|
NZ244306A
(en)
*
|
1991-09-30 |
1995-07-26 |
Boehringer Ingelheim Int |
Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
|
WO1993018759A1
(en)
*
|
1992-03-20 |
1993-09-30 |
Baylor College Of Medicine |
A dna transporter system and method of use
|
DK0636028T3
(da)
*
|
1992-04-03 |
2004-07-12 |
Univ California |
Selvorganiserende polynucleotidleveringssystem omfattende et amfipatisk kationisk peptid
|
WO1994006923A1
(en)
*
|
1992-09-24 |
1994-03-31 |
The University Of Connecticut |
Modification of a virus to redirect infectivity and enhance targeted delivery of polynucleotides to cells
|
CA2158655A1
(en)
*
|
1993-03-19 |
1994-09-29 |
Max L. Birnstiel |
Process for preparing cancer vaccines
|
DE4311651A1
(de)
*
|
1993-04-08 |
1994-10-13 |
Boehringer Ingelheim Int |
Virus für den Transport von Fremd-DNA in höhere eukaryotische Zellen
|
WO1995002698A1
(en)
*
|
1993-07-12 |
1995-01-26 |
Life Technologies, Inc. |
Composition and methods for transfecting eukaryotic cells
|
DE4335025A1
(de)
*
|
1993-10-14 |
1995-04-20 |
Boehringer Ingelheim Int |
Endosomolytisch wirksame Partikel
|
EP0648493A1
(en)
*
|
1993-10-19 |
1995-04-19 |
Tadatsugu Prof. Dr. Taniguchi |
A method to reverse the phenotype of transformed cells by the transcription factor IRF-1
|
US5928944A
(en)
*
|
1994-02-04 |
1999-07-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
Method of adenoviral-medicated cell transfection
|
MX9603866A
(es)
*
|
1994-03-18 |
1997-03-29 |
Boehringer Ingelheim Int |
Procedimiento para el tratamiento de celulas eucarioticas.
|
WO1995026411A2
(en)
*
|
1994-03-25 |
1995-10-05 |
The Uab Research Foundation |
Composition and methods for creating syngeneic recombinant virus-producing cells
|
US5670347A
(en)
|
1994-05-11 |
1997-09-23 |
Amba Biosciences Llc |
Peptide-mediated gene transfer
|
EP0767840A2
(de)
|
1994-05-30 |
1997-04-16 |
BOEHRINGER INGELHEIM INTERNATIONAL GmbH |
Verfahren zum einbringen von fremdmaterial in höhere eukaryotische zellen
|
DE4418965A1
(de)
*
|
1994-05-31 |
1995-12-07 |
Boehringer Ingelheim Int |
Verfahren zum Einbringen von Nukleinsäure in höhere eukaryotische Zellen
|
DE4426429A1
(de)
*
|
1994-07-26 |
1996-02-01 |
Boehringer Ingelheim Int |
Verfahren zum Einführen von DNA in höhere eukaryotische Zellen
|
US6468981B1
(en)
|
1994-07-29 |
2002-10-22 |
Emory University |
Compositions and methods for targeting pharmaceutically active materials to cells containing androgen receptors
|
US5525606A
(en)
|
1994-08-01 |
1996-06-11 |
The United States Of America As Represented By The Department Of Health And Human Services |
Substituted 06-benzylguanines and 6(4)-benzyloxypyrimidines
|
US6465253B1
(en)
|
1994-09-08 |
2002-10-15 |
Genvec, Inc. |
Vectors and methods for gene transfer to cells
|
US5846782A
(en)
|
1995-11-28 |
1998-12-08 |
Genvec, Inc. |
Targeting adenovirus with use of constrained peptide motifs
|
US5559099A
(en)
*
|
1994-09-08 |
1996-09-24 |
Genvec, Inc. |
Penton base protein and methods of using same
|
US5965541A
(en)
*
|
1995-11-28 |
1999-10-12 |
Genvec, Inc. |
Vectors and methods for gene transfer to cells
|
US5962311A
(en)
*
|
1994-09-08 |
1999-10-05 |
Genvec, Inc. |
Short-shafted adenoviral fiber and its use
|
US5837533A
(en)
*
|
1994-09-28 |
1998-11-17 |
American Home Products Corporation |
Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent
|
WO1996010089A1
(fr)
*
|
1994-09-29 |
1996-04-04 |
Ajinomoto Co., Inc. |
Modification d'un peptide et d'une proteine
|
US6221959B1
(en)
|
1994-11-18 |
2001-04-24 |
Supratek Pharma, Inc. |
Polynucleotide compositions
|
US6359054B1
(en)
|
1994-11-18 |
2002-03-19 |
Supratek Pharma Inc. |
Polynucleotide compositions for intramuscular administration
|
US6008202A
(en)
*
|
1995-01-23 |
1999-12-28 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
US5795587A
(en)
*
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
US6127525A
(en)
*
|
1995-02-21 |
2000-10-03 |
Cornell Research Foundation, Inc. |
Chimeric adenoviral coat protein and methods of using same
|
US5770442A
(en)
*
|
1995-02-21 |
1998-06-23 |
Cornell Research Foundation, Inc. |
Chimeric adenoviral fiber protein and methods of using same
|
WO1996028563A1
(en)
*
|
1995-03-09 |
1996-09-19 |
Bavarian Nordic |
Vectors carrying therapeutic genes encoding antimicrobial peptides for gene therapy
|
WO1996029423A1
(en)
*
|
1995-03-20 |
1996-09-26 |
Baylor College Of Medicine |
Compositions and methods for inducing infection by retroviral vectors outside of their host range
|
DE19510344C1
(de)
*
|
1995-03-22 |
1996-11-07 |
Boehringer Ingelheim Int |
Verwendung einer Tumorvakzine
|
US6420549B1
(en)
|
1995-06-06 |
2002-07-16 |
Isis Pharmaceuticals, Inc. |
Oligonucleotide analogs having modified dimers
|
WO1996040958A1
(en)
*
|
1995-06-07 |
1996-12-19 |
Baylor College Of Medicine |
Nucleic acid transporters for delivery of nucleic acids into a cell
|
US20030069173A1
(en)
*
|
1998-03-16 |
2003-04-10 |
Life Technologies, Inc. |
Peptide-enhanced transfections
|
US6051429A
(en)
|
1995-06-07 |
2000-04-18 |
Life Technologies, Inc. |
Peptide-enhanced cationic lipid transfections
|
AU5979296A
(en)
*
|
1995-06-07 |
1996-12-30 |
Life Technologies, Inc. |
Peptide-enhanced cationic lipid transfections
|
US6783980B2
(en)
*
|
1995-06-15 |
2004-08-31 |
Crucell Holland B.V. |
Packaging systems for human recombinant adenovirus to be used in gene therapy
|
US5994128A
(en)
*
|
1995-06-15 |
1999-11-30 |
Introgene B.V. |
Packaging systems for human recombinant adenovirus to be used in gene therapy
|
US5908777A
(en)
*
|
1995-06-23 |
1999-06-01 |
University Of Pittsburgh |
Lipidic vector for nucleic acid delivery
|
GB9515356D0
(en)
*
|
1995-07-26 |
1995-09-20 |
Medical Res Council |
Improvements in or relating to delivery of nucleic acid
|
US5770720A
(en)
*
|
1995-08-30 |
1998-06-23 |
Barnes-Jewish Hospital |
Ubiquitin conjugating enzymes having transcriptional repressor activity
|
IL115199A
(en)
|
1995-09-07 |
2005-05-17 |
Opperbas Holding Bv |
Composition comprising a polynucleic acid molecule in a liposome and method using said composition
|
US6630351B1
(en)
*
|
1999-06-07 |
2003-10-07 |
Mirus Corporation |
Compositions and methods for drug delivery using pH sensitive molecules
|
CA2190304A1
(en)
*
|
1995-12-15 |
1997-06-16 |
Elazar Rabbani |
Property effecting and/or property exhibiting compositions for therapeutic and diagnostic uses
|
ATE333892T1
(de)
*
|
1996-02-09 |
2006-08-15 |
Pi-Wan Cheng |
Kationisches lipid und rezeptorligand erleichterte gabe von biologisch aktiven molekuelen
|
DE19605548A1
(de)
*
|
1996-02-15 |
1997-09-04 |
Boehringer Ingelheim Int |
Zusammensetzung für die Transfektion höherer eukaryotischer Zellen
|
AU728146B2
(en)
*
|
1996-03-14 |
2001-01-04 |
Immune Response Corporation, The |
Targeted delivery of genes encoding interferon
|
DE19615803A1
(de)
|
1996-04-20 |
1997-10-23 |
Boehringer Ingelheim Int |
CELO-Virus
|
US9096636B2
(en)
|
1996-06-06 |
2015-08-04 |
Isis Pharmaceuticals, Inc. |
Chimeric oligomeric compounds and their use in gene modulation
|
US5898031A
(en)
|
1996-06-06 |
1999-04-27 |
Isis Pharmaceuticals, Inc. |
Oligoribonucleotides for cleaving RNA
|
US7812149B2
(en)
|
1996-06-06 |
2010-10-12 |
Isis Pharmaceuticals, Inc. |
2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
|
JP4320054B2
(ja)
*
|
1996-08-13 |
2009-08-26 |
ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド |
ポリヌクレオチド送達のための組成物および方法
|
DE19632532A1
(de)
*
|
1996-08-13 |
1998-02-19 |
Boehringer Ingelheim Int |
Verfahren zur Herstellung von Säugetieren mit definierten genetischen Eigenschaften
|
US5948681A
(en)
*
|
1996-08-14 |
1999-09-07 |
Children's Hospital Of Philadelphia |
Non-viral vehicles for use in gene transfer
|
CN1181422A
(zh)
*
|
1996-10-31 |
1998-05-13 |
上海市肿瘤研究所 |
与生长因子受体结合的多肽所构建的基因转移载体
|
US6544523B1
(en)
|
1996-11-13 |
2003-04-08 |
Chiron Corporation |
Mutant forms of Fas ligand and uses thereof
|
US5965441A
(en)
*
|
1996-11-13 |
1999-10-12 |
The General Hospital Coporation |
HSV/AAV hybrid amplicon vectors
|
US20060002949A1
(en)
|
1996-11-14 |
2006-01-05 |
Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. |
Transcutaneous immunization without heterologous adjuvant
|
US6797276B1
(en)
|
1996-11-14 |
2004-09-28 |
The United States Of America As Represented By The Secretary Of The Army |
Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
|
US5980898A
(en)
|
1996-11-14 |
1999-11-09 |
The United States Of America As Represented By The U.S. Army Medical Research & Material Command |
Adjuvant for transcutaneous immunization
|
AU5729898A
(en)
*
|
1996-12-18 |
1998-07-15 |
Emory University |
Polycationic oligomers
|
CA2283639A1
(en)
*
|
1997-03-14 |
1998-09-24 |
The Children's Hospital Of Philadelphia |
Methods and compositions for use in gene therapy for treatment of hemophilia
|
US20040009166A1
(en)
*
|
1997-04-30 |
2004-01-15 |
Filpula David R. |
Single chain antigen-binding polypeptides for polymer conjugation
|
WO1998049198A1
(en)
*
|
1997-04-30 |
1998-11-05 |
Enzon, Inc. |
Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof
|
US6635623B1
(en)
|
1997-06-13 |
2003-10-21 |
Baylor College Of Medicine |
Lipoproteins as nucleic acid vectors
|
US20050096288A1
(en)
*
|
1997-06-13 |
2005-05-05 |
Aragene, Inc. |
Lipoproteins as nucleic acid vectors
|
DE19726186A1
(de)
*
|
1997-06-20 |
1998-12-24 |
Boehringer Ingelheim Int |
Komplexe für den Transport von Nukleinsäure in höhere eukaryotische Zellen
|
US6172211B1
(en)
|
1997-07-11 |
2001-01-09 |
Boehringer Ingelheim International Gmbh |
Nucleic acid encoding tag7 polypeptide
|
EP1007099A4
(en)
|
1997-07-11 |
2004-11-24 |
Univ Brandeis |
METHOD FOR INDUCING APOPTOSE BY LOWERING THE THIAMINE MIRROR
|
US7923250B2
(en)
|
1997-07-30 |
2011-04-12 |
Warsaw Orthopedic, Inc. |
Methods of expressing LIM mineralization protein in non-osseous cells
|
ATE417927T1
(de)
|
1997-07-30 |
2009-01-15 |
Univ Emory |
Neue knochenmineralisierungsproteine, dna, vektoren, expressionssysteme
|
WO1999007723A1
(en)
*
|
1997-08-07 |
1999-02-18 |
University Of Maryland, Baltimore |
Nucleic acid uptake and release vehicle
|
US20030125278A1
(en)
*
|
1997-08-13 |
2003-07-03 |
Tang De-Chu C. |
Immunization of animals by topical applications of a salmonella-based vector
|
US20030045492A1
(en)
*
|
1997-08-13 |
2003-03-06 |
Tang De-Chu C. |
Vaccination by topical application of recombinant vectors
|
US6197332B1
(en)
*
|
1997-08-13 |
2001-03-06 |
Chiron Corporation |
Lipid-conjugated polyamide compounds and related compositions and methods thereof
|
US6706693B1
(en)
|
1997-08-13 |
2004-03-16 |
The Uab Research Foundation |
Vaccination by topical application of genetic vectors
|
US6348450B1
(en)
|
1997-08-13 |
2002-02-19 |
The Uab Research Foundation |
Noninvasive genetic immunization, expression products therefrom and uses thereof
|
US6716823B1
(en)
|
1997-08-13 |
2004-04-06 |
The Uab Research Foundation |
Noninvasive genetic immunization, expression products therefrom, and uses thereof
|
US5998386A
(en)
|
1997-09-19 |
1999-12-07 |
Feldman; Arthur M. |
Pharmaceutical compositions and method of using same for the treatment of failing myocardial tissue
|
US6555367B1
(en)
*
|
1997-10-10 |
2003-04-29 |
The United States Of America As Represented By The Department Of Health And Human Services |
Complex of biotinylated viral vector and ligand for targeted gene delivery
|
US6914131B1
(en)
|
1998-10-09 |
2005-07-05 |
Chiron S.R.L. |
Neisserial antigens
|
CA2671261A1
(en)
|
1997-11-06 |
1999-05-20 |
Novartis Vaccines And Diagnostics S.R.L. |
Neisserial antigens
|
WO1999025863A1
(en)
*
|
1997-11-14 |
1999-05-27 |
Cedars-Sinai Medical Center |
Transfection and transfer of male germ cells for generation of transgenic species
|
US6734338B1
(en)
|
1997-11-14 |
2004-05-11 |
Cedars-Sinai Medical Center |
Transfection, storage and transfer of male germ cells for generation of transgenic species and genetic therapies
|
US7294755B1
(en)
|
1997-11-14 |
2007-11-13 |
Cedars-Sinai Medical Center |
Genetic modification of male germ cells for generation of transgenic species and genetic therapies
|
EP0945138A1
(en)
*
|
1997-12-04 |
1999-09-29 |
Université Louis Pasteur de Strasbourg |
Transfection particles
|
CA2317549C
(en)
*
|
1998-01-05 |
2006-04-11 |
University Of Washington |
Composition for enhancing transport through lipid-containing membranes, and uses thereof
|
PT1047784E
(pt)
|
1998-01-14 |
2009-12-21 |
Novartis Vaccines & Diagnostic |
Antigénios de neisseria meningitidis
|
AU4070499A
(en)
|
1998-04-30 |
1999-11-16 |
Cornell Research Foundation Inc. |
Adenoviral vectors with tandem fiber proteins
|
ES2304065T3
(es)
|
1998-05-01 |
2008-09-01 |
Novartis Vaccines And Diagnostics, Inc. |
Antigenos y composiciones de neisseria meningitidis.
|
US7244714B1
(en)
*
|
1998-06-12 |
2007-07-17 |
Aradigm Corporation |
Methods of delivering aerosolized polynucleotides to the respiratory tract
|
US6509323B1
(en)
|
1998-07-01 |
2003-01-21 |
California Institute Of Technology |
Linear cyclodextrin copolymers
|
US7091192B1
(en)
*
|
1998-07-01 |
2006-08-15 |
California Institute Of Technology |
Linear cyclodextrin copolymers
|
US6245427B1
(en)
|
1998-07-06 |
2001-06-12 |
DüZGüNES NEJAT |
Non-ligand polypeptide and liposome complexes as intracellular delivery vehicles
|
US20040043489A1
(en)
*
|
1998-07-08 |
2004-03-04 |
Menzo Havenga |
Gene delivery vectors provided with a tissue tropism for dendritic cells and methods of use
|
US20030017138A1
(en)
*
|
1998-07-08 |
2003-01-23 |
Menzo Havenga |
Chimeric adenoviruses
|
US7396919B1
(en)
*
|
1998-07-17 |
2008-07-08 |
Mirus Bio Corporation |
Charge reversal of polyion complexes
|
WO2000011019A1
(en)
*
|
1998-08-21 |
2000-03-02 |
Felix Frey |
Conjugates of dna interacting groups with steroid hormones for use as nucleic acid transfection agent
|
WO2000015823A1
(en)
|
1998-09-11 |
2000-03-23 |
Genvec, Inc. |
Alternatively targeted adenovirus
|
US6077709A
(en)
|
1998-09-29 |
2000-06-20 |
Isis Pharmaceuticals Inc. |
Antisense modulation of Survivin expression
|
JP2002527066A
(ja)
|
1998-10-15 |
2002-08-27 |
カイロン コーポレイション |
転移性乳癌および結腸癌調節遺伝子
|
US6333396B1
(en)
|
1998-10-20 |
2001-12-25 |
Enzon, Inc. |
Method for targeted delivery of nucleic acids
|
EP2298728A1
(en)
|
1998-11-12 |
2011-03-23 |
Life Technologies Corporation |
Transfection reagents
|
CN100572542C
(zh)
|
1998-11-19 |
2009-12-23 |
乔治敦大学 |
系统性病毒/配体基因输送系统和基因治疗
|
US20050063950A1
(en)
*
|
1998-11-19 |
2005-03-24 |
Georgetown University |
Systemic viral/ligand gene delivery system and gene therapy
|
US6929946B1
(en)
|
1998-11-20 |
2005-08-16 |
Crucell Holland B.V. |
Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells
|
WO2000036118A2
(en)
|
1998-12-16 |
2000-06-22 |
Chiron Corporation |
HUMAN CYCLIN-DEPENDENT KINASE (hPNQALRE)
|
US7098192B2
(en)
|
1999-04-08 |
2006-08-29 |
Isis Pharmaceuticals, Inc. |
Antisense oligonucleotide modulation of STAT3 expression
|
GB9908195D0
(en)
|
1999-04-09 |
1999-06-02 |
Microbiological Res Authority |
Treatment of intracellular infection
|
DE19918446A1
(de)
*
|
1999-04-23 |
2000-11-23 |
Univ Eberhard Karls |
Verwendung von Coxsackievirus B3 zur Verbesserung der Transfektion von Zellen
|
US6514762B1
(en)
|
1999-04-23 |
2003-02-04 |
New Mexico State University Technology Transfer Corporation |
Delivery of nucleotides by electrochemical release
|
BR0010130A
(pt)
|
1999-04-30 |
2002-06-04 |
Chiron Spa |
Antìgenos de neisseria conservados
|
US20040009936A1
(en)
*
|
1999-05-03 |
2004-01-15 |
Tang De-Chu C. |
Vaccine and drug delivery by topical application of vectors and vector extracts
|
US6913922B1
(en)
*
|
1999-05-18 |
2005-07-05 |
Crucell Holland B.V. |
Serotype of adenovirus and uses thereof
|
US20050232900A1
(en)
*
|
1999-05-18 |
2005-10-20 |
Crucell Holland B.V. |
Serotype of adenovirus and uses thereof
|
US6492169B1
(en)
|
1999-05-18 |
2002-12-10 |
Crucell Holland, B.V. |
Complementing cell lines
|
GB9911683D0
(en)
|
1999-05-19 |
1999-07-21 |
Chiron Spa |
Antigenic peptides
|
US6696272B1
(en)
|
1999-06-02 |
2004-02-24 |
Hsc Research & Development Limited Partnership |
Products and methods for gaucher disease therapy
|
US8541548B2
(en)
*
|
1999-06-07 |
2013-09-24 |
Arrowhead Madison Inc. |
Compounds and methods for reversible modification of biologically active molecules
|
US20080281041A1
(en)
|
1999-06-07 |
2008-11-13 |
Rozema David B |
Reversibly Masked Polymers
|
GB9916529D0
(en)
|
1999-07-14 |
1999-09-15 |
Chiron Spa |
Antigenic peptides
|
DE60017924T2
(de)
*
|
1999-09-17 |
2006-03-30 |
Tgt Laboratories, S.A. De C.V. |
Rekombinante, adenovirale vektoren und ihre verwendung zur behandlung von leberzirrhose
|
RU2281956C2
(ru)
|
1999-10-29 |
2006-08-20 |
Чирон С.Р.Л. |
Антигенные пептиды neisseria
|
AU3366901A
(en)
*
|
1999-12-30 |
2001-07-16 |
Novartis Ag |
Novel colloid synthetic vectors for gene therapy
|
US7737108B1
(en)
|
2000-01-07 |
2010-06-15 |
University Of Washington |
Enhanced transport using membrane disruptive agents
|
EP2289545B1
(en)
|
2000-01-17 |
2016-06-08 |
GlaxoSmithKline Biologicals SA |
Supplemented OMV vaccine against meningococcus
|
US20020055479A1
(en)
|
2000-01-18 |
2002-05-09 |
Cowsert Lex M. |
Antisense modulation of PTP1B expression
|
US6261840B1
(en)
|
2000-01-18 |
2001-07-17 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of PTP1B expression
|
DK2270030T3
(da)
|
2000-02-28 |
2012-08-13 |
Novartis Vaccines & Diagnostic |
Heterolog ekspression af Neisseria-proteiner
|
US6680172B1
(en)
|
2000-05-16 |
2004-01-20 |
Regents Of The University Of Michigan |
Treatments and markers for cancers of the central nervous system
|
EP1157999A1
(en)
*
|
2000-05-24 |
2001-11-28 |
Introgene B.V. |
Methods and means for enhancing skin transplantation using gene delivery vehicles having tropism for primary fibroblasts, as well as other uses thereof
|
EP1950297A2
(en)
|
2000-05-31 |
2008-07-30 |
Novartis Vaccines and Diagnostics, Inc. |
Compositions and methods for treating neoplastic disease using chemotherapy and radiation sensitizers
|
EP1301612A2
(en)
*
|
2000-05-31 |
2003-04-16 |
Genvec, Inc. |
Method and composition for targeting an adenoviral vector
|
DE10130849A1
(de)
|
2000-06-28 |
2002-06-06 |
Max Delbrueck Centrum |
Verfahren zur Verbesserung der Transfektionseffizienz
|
AU2001260729A1
(en)
*
|
2000-07-26 |
2002-02-13 |
Cho, Sung-Woo |
Oligolysine transducing domain, oligolysine-cargo molecule complex and uses thereof
|
US7198924B2
(en)
|
2000-12-11 |
2007-04-03 |
Invitrogen Corporation |
Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
|
AU2002223556A1
(en)
*
|
2000-09-20 |
2002-04-02 |
Crucell Holland B.V. |
Transduction of dendritic cells using adenoviral vectors
|
DE60138403D1
(de)
*
|
2000-09-26 |
2009-05-28 |
Crucell Holland Bv |
Adenovirale vektoren für die übertragung von genen in zellen der skelettmuskulatur oder myoblasten
|
EP1191104A1
(en)
*
|
2000-09-26 |
2002-03-27 |
Introgene B.V. |
Gene delivery vehicles and use thereof in the preparation of a medicament and/or vaccine
|
DE10049010A1
(de)
*
|
2000-10-04 |
2002-04-18 |
Boehringer Ingelheim Int |
Transferrin-Polykation/DNS-Komplexe für die systemische Therapie von Tumorerkrankungen mit zytotoxischen Proteinen
|
EP1337664A4
(en)
*
|
2000-10-27 |
2005-01-19 |
Invitrogen Corp |
METHOD FOR INTRODUCING ANTISENSE OLIGONUCLEOTIDES IN EUKARYOTIC CELLS
|
ES2330083T3
(es)
|
2000-10-27 |
2009-12-04 |
Novartis Vaccines And Diagnostics S.R.L. |
Acidos nucleicos y proteinas de estreptococos de los grupos a y b.
|
US6892140B1
(en)
*
|
2000-11-27 |
2005-05-10 |
Enteron, Inc. |
Immunogenic cancer peptides and uses thereof
|
MXPA00011713A
(es)
*
|
2000-11-28 |
2002-05-31 |
Tgt Lab S A De C V |
Vectores recombinantes virales y no virales conteniendo el gen humano del activador de plasminogeno derivado de urocinasa y su utilidad en el tratamiento de diversos tipos de fibrosis hepatica, renal, pulmonar, pancreatica, cardiaca y cicatrices hipe
|
US7635571B2
(en)
*
|
2000-12-07 |
2009-12-22 |
Siemens Healthcare Diagnostics Products Gmbh |
Amplified signal in binding assays
|
US6635466B2
(en)
*
|
2001-01-09 |
2003-10-21 |
University Of Iowa Research Foundation |
Adenovirus serotype 30 (Ad30)
|
WO2002062823A2
(en)
*
|
2001-02-02 |
2002-08-15 |
Yale University |
Peptides for facilitating composite receptor expression and translocation of macromolecules
|
EP1372708B1
(en)
|
2001-02-13 |
2008-06-18 |
GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE ARMY |
Vaccine for transcutaneous immunization against travellers' diarrhoea
|
US20020150566A1
(en)
*
|
2001-03-23 |
2002-10-17 |
Kun-Liang Guan |
Method of inhibiting cancerous cell proliferation using Ras mutants of GDP-bound conformation
|
GB0107661D0
(en)
|
2001-03-27 |
2001-05-16 |
Chiron Spa |
Staphylococcus aureus
|
GB0107658D0
(en)
|
2001-03-27 |
2001-05-16 |
Chiron Spa |
Streptococcus pneumoniae
|
US20020193295A1
(en)
*
|
2001-05-04 |
2002-12-19 |
Emanuel Calenoff |
Immunogenic peptides and uses thereof
|
CA2445947A1
(en)
*
|
2001-04-30 |
2002-11-07 |
Targeted Genetics Corporation |
Lipid-comprising drug delivery complexes and methods for their production
|
WO2002089586A1
(en)
*
|
2001-05-10 |
2002-11-14 |
St. Jude Children's Research Hospital |
Lung epithelial cell line for propagating viruses
|
US20030003074A1
(en)
*
|
2001-06-14 |
2003-01-02 |
Macromed, Inc. |
Formulations of lymphokines and method of use thereof for local or both local and systemic control of proliferative cell disorders
|
US20060159657A1
(en)
*
|
2001-06-14 |
2006-07-20 |
Macromed, Incorporated |
Formulations of lymphokines and method of use thereof for local or both local and systemic control of proliferative cell disorders
|
US7803915B2
(en)
|
2001-06-20 |
2010-09-28 |
Genentech, Inc. |
Antibody compositions for the diagnosis and treatment of tumor
|
CA2633171C
(en)
|
2001-06-20 |
2012-11-20 |
Genentech, Inc. |
Antibodies against tumor-associated antigenic target (tat) polypeptides
|
AU2002315393A1
(en)
|
2001-06-21 |
2003-01-08 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of superoxide dismutase 1, soluble expression
|
US6964950B2
(en)
|
2001-07-25 |
2005-11-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of C-reactive protein expression
|
US7425545B2
(en)
|
2001-07-25 |
2008-09-16 |
Isis Pharmaceuticals, Inc. |
Modulation of C-reactive protein expression
|
US20030096772A1
(en)
|
2001-07-30 |
2003-05-22 |
Crooke Rosanne M. |
Antisense modulation of acyl CoA cholesterol acyltransferase-2 expression
|
US7407943B2
(en)
|
2001-08-01 |
2008-08-05 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of apolipoprotein B expression
|
US7227014B2
(en)
|
2001-08-07 |
2007-06-05 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of apolipoprotein (a) expression
|
GB0120022D0
(en)
*
|
2001-08-16 |
2001-10-10 |
Photobiotics Ltd |
Conjugate
|
CA2460120A1
(en)
|
2001-09-18 |
2003-03-27 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
WO2003052117A2
(en)
*
|
2001-09-19 |
2003-06-26 |
Massachusetts Institute Of Technology |
Methods and products related to non-viral transfection
|
NZ566396A
(en)
|
2001-10-09 |
2009-07-31 |
Isis Pharmaceuticals Inc |
Antisense modulation of insulin-like growth factor binding protein 5 expressions
|
US6750019B2
(en)
|
2001-10-09 |
2004-06-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of insulin-like growth factor binding protein 5 expression
|
US7745418B2
(en)
*
|
2001-10-12 |
2010-06-29 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting viral replication
|
JP2005508396A
(ja)
*
|
2001-11-02 |
2005-03-31 |
イントラディグム、コーポレイション |
核酸送達ビヒクルのための治療方法
|
EP2325193A3
(en)
|
2001-11-02 |
2012-05-02 |
Insert Therapeutics, Inc. |
Methods and compositions for therapeutic use of RNA interference
|
US6965025B2
(en)
|
2001-12-10 |
2005-11-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of connective tissue growth factor expression
|
RU2331435C2
(ru)
|
2001-12-12 |
2008-08-20 |
Чирон Срл. |
Иммунизация против chlamydia trachomatis
|
KR20080106369A
(ko)
|
2002-01-02 |
2008-12-04 |
제넨테크, 인크. |
종양의 진단 및 치료 방법 및 이를 위한 조성물
|
US8138383B2
(en)
*
|
2002-03-11 |
2012-03-20 |
Arrowhead Madison Inc. |
Membrane active heteropolymers
|
US8008355B2
(en)
*
|
2002-03-11 |
2011-08-30 |
Roche Madison Inc. |
Endosomolytic poly(vinyl ether) polymers
|
AU2003220161A1
(en)
*
|
2002-03-12 |
2003-09-29 |
Nitto Denko Corporation |
Vector for transfection of eukaryotic cells
|
WO2003077864A2
(en)
*
|
2002-03-15 |
2003-09-25 |
Department Of Veterans Affairs, Rehabilitation R & D Service |
Methods and compositions for directing cells to target organs
|
US20030180712A1
(en)
|
2002-03-20 |
2003-09-25 |
Biostratum Ab |
Inhibition of the beta3 subunit of L-type Ca2+ channels
|
KR20040101502A
(ko)
|
2002-04-16 |
2004-12-02 |
제넨테크, 인크. |
종양의 진단 및 치료 방법 및 이를 위한 조성물
|
SI1497438T1
(sl)
*
|
2002-04-25 |
2010-03-31 |
Crucell Holland Bv |
Sredstva in postopki za pripravo adenovirusnih vektorjev
|
US20040142450A1
(en)
*
|
2002-05-10 |
2004-07-22 |
Seo Sang Heui |
Lung epithelial cell line for propagating viruses
|
US7199107B2
(en)
|
2002-05-23 |
2007-04-03 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of kinesin-like 1 expression
|
US20050233993A1
(en)
*
|
2002-06-05 |
2005-10-20 |
Kadonaga James T |
Methods for promoting homologous recombination
|
DE60324925D1
(de)
|
2002-06-19 |
2009-01-08 |
Univ Health Network |
Ace2-aktivierung zur behandlung von herz, lungen, und nierenkrankheit und bluthochdruck
|
US20060003316A1
(en)
*
|
2002-07-15 |
2006-01-05 |
John Simard |
Immunogenic compositions derived from poxviruses and methods of using same
|
KR101476067B1
(ko)
|
2002-09-06 |
2014-12-23 |
인설트 테라페틱스, 인코퍼레이티드 |
공유결합된 치료제 전달을 위한 사이클로덱스트린-기초 중합체
|
US20050260601A1
(en)
*
|
2002-09-09 |
2005-11-24 |
Whitt Michael A |
Recombinant mutants of rhabdovirus and methods of use thereof
|
EP2330194A3
(en)
|
2002-09-13 |
2011-10-12 |
Replicor, Inc. |
Non-sequence complementary antiviral oligonucleotides
|
EP2272958A1
(en)
|
2002-09-26 |
2011-01-12 |
ISIS Pharmaceuticals, Inc. |
Modulation of forkhead box O1A expression
|
EP1554575A2
(en)
*
|
2002-10-10 |
2005-07-20 |
The U.S. Government represented by The Department of Veterans Affairs |
Detection, localization and staging of tumors using labeled activated lymphocytes directed to a tumor specific epitope
|
WO2004044138A2
(en)
|
2002-11-05 |
2004-05-27 |
Isis Pharmaceuticals, Inc. |
Chimeric oligomeric compounds and their use in gene modulation
|
WO2004044132A2
(en)
|
2002-11-05 |
2004-05-27 |
Isis Pharmaceuticals, Inc. |
Modified oligonucleotides for use in rna interference
|
US20080026077A1
(en)
*
|
2002-11-12 |
2008-01-31 |
John Hilfinger |
Methods and compositions of gene delivery agents for systemic and local therapy
|
US20050026859A1
(en)
*
|
2002-11-12 |
2005-02-03 |
John Hilfinger |
Methods and compositions of gene delivery agents for systemic and local therapy
|
WO2004044181A2
(en)
|
2002-11-13 |
2004-05-27 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of apolipoprotein b expression
|
SI2336318T1
(sl)
|
2002-11-13 |
2013-07-31 |
Genzyme Corporation |
Protismiselna modulacija ekspresije apolipoproteina B
|
US7144999B2
(en)
|
2002-11-23 |
2006-12-05 |
Isis Pharmaceuticals, Inc. |
Modulation of hypoxia-inducible factor 1 alpha expression
|
NZ541637A
(en)
|
2003-02-11 |
2008-07-31 |
Antisense Therapeutics Pty Ltd |
Modulation of insulin like growth factor I receptor
|
US7803781B2
(en)
|
2003-02-28 |
2010-09-28 |
Isis Pharmaceuticals, Inc. |
Modulation of growth hormone receptor expression and insulin-like growth factor expression
|
US20040185559A1
(en)
|
2003-03-21 |
2004-09-23 |
Isis Pharmaceuticals Inc. |
Modulation of diacylglycerol acyltransferase 1 expression
|
US7217566B2
(en)
*
|
2003-03-24 |
2007-05-15 |
Invitrogen Corporation |
Attached cell lines
|
GB0308198D0
(en)
|
2003-04-09 |
2003-05-14 |
Chiron Srl |
ADP-ribosylating bacterial toxin
|
US7598227B2
(en)
|
2003-04-16 |
2009-10-06 |
Isis Pharmaceuticals Inc. |
Modulation of apolipoprotein C-III expression
|
WO2004093788A2
(en)
*
|
2003-04-17 |
2004-11-04 |
The Trustees Of Columbia University In The City Ofnew York |
Desmoglein 4 is a novel gene involved in hair growth
|
US7399853B2
(en)
|
2003-04-28 |
2008-07-15 |
Isis Pharmaceuticals |
Modulation of glucagon receptor expression
|
US20040220085A1
(en)
*
|
2003-05-02 |
2004-11-04 |
Jasbir Sandhu |
Compositions for nucleic acid delivery
|
US20040220084A1
(en)
*
|
2003-05-02 |
2004-11-04 |
Jasbir Sandhu |
Methods for nucleic acid delivery
|
US7541344B2
(en)
|
2003-06-03 |
2009-06-02 |
Eli Lilly And Company |
Modulation of survivin expression
|
EP1639109B1
(en)
*
|
2003-06-09 |
2011-04-13 |
Corixa Corporation |
Dna vectors
|
WO2005007819A2
(en)
*
|
2003-07-09 |
2005-01-27 |
Wisconsin Alumni Research Foundation |
Charge-dynamic polymers and delivery of anionic compounds
|
EP2530157B1
(en)
|
2003-07-31 |
2016-09-28 |
Regulus Therapeutics Inc. |
Oligomeric compounds and compositions for use in modulation of miRNAs
|
US7825235B2
(en)
|
2003-08-18 |
2010-11-02 |
Isis Pharmaceuticals, Inc. |
Modulation of diacylglycerol acyltransferase 2 expression
|
SG146682A1
(en)
|
2003-09-18 |
2008-10-30 |
Isis Pharmaceuticals Inc |
Modulation of eif4e expression
|
NZ546272A
(en)
|
2003-10-10 |
2009-05-31 |
Alchemia Oncology Pty Ltd |
The modulation of hyaluronan synthesis and degradation in the treatment of disease
|
EP2083089A1
(en)
*
|
2003-10-23 |
2009-07-29 |
Illumigen Biosciences, Inc. |
Detection of mutations in a gene associated with resistance to viral infection, oas1
|
US8062891B2
(en)
|
2003-10-24 |
2011-11-22 |
Gencia Corporation |
Nonviral vectors for delivering polynucleotides to plants
|
US20090208478A1
(en)
*
|
2003-10-24 |
2009-08-20 |
Gencia Corporation |
Transducible polypeptides for modifying metabolism
|
CA2543257C
(en)
|
2003-10-24 |
2013-12-31 |
Gencia Corporation |
Methods and compositions for delivering polynucleotides
|
US20090123468A1
(en)
|
2003-10-24 |
2009-05-14 |
Gencia Corporation |
Transducible polypeptides for modifying metabolism
|
US8507277B2
(en)
|
2003-10-24 |
2013-08-13 |
Gencia Corporation |
Nonviral vectors for delivering polynucleotides
|
US8133733B2
(en)
|
2003-10-24 |
2012-03-13 |
Gencia Corporation |
Nonviral vectors for delivering polynucleotides to target tissues
|
US20050191653A1
(en)
|
2003-11-03 |
2005-09-01 |
Freier Susan M. |
Modulation of SGLT2 expression
|
SI2161283T1
(sl)
|
2003-11-17 |
2014-10-30 |
Genentech, Inc. |
Sestavki, ki obsegajo protitelesa proti CD79b, konjugirana na sredstvo, ki inhibira rast, ali na citotoksično sredstvo, in postopki za zdravljenje tumorja hematopoetskega izvora
|
EP1697534B1
(en)
|
2003-12-01 |
2010-06-02 |
Life Technologies Corporation |
Nucleic acid molecules containing recombination sites and methods of using the same
|
SG113562A1
(en)
*
|
2004-01-12 |
2005-08-29 |
Agency Science Tech & Res |
Polyalkyleneimine-graft-biodegradable polymers for delivery of bioactive agents
|
JP2007520222A
(ja)
|
2004-01-20 |
2007-07-26 |
アイシス ファーマシューティカルズ インコーポレイテッド |
グルココルチコイドレセプター発現の調節
|
US7468431B2
(en)
|
2004-01-22 |
2008-12-23 |
Isis Pharmaceuticals, Inc. |
Modulation of eIF4E-BP2 expression
|
US20050227940A1
(en)
*
|
2004-01-23 |
2005-10-13 |
City Of Hope |
Amplifying interfering RNA (RNAi) expression and effects
|
US8569474B2
(en)
|
2004-03-09 |
2013-10-29 |
Isis Pharmaceuticals, Inc. |
Double stranded constructs comprising one or more short strands hybridized to a longer strand
|
US20050203047A1
(en)
*
|
2004-03-10 |
2005-09-15 |
Ulrich Thomann |
Delivery vectors for short interfering RNA, micro-RNA and antisense RNA
|
EP1730309B1
(en)
|
2004-03-15 |
2016-05-04 |
Ionis Pharmaceuticals, Inc. |
Compositions and methods for optimizing cleavage of rna by rnase h
|
WO2005097207A2
(en)
*
|
2004-03-26 |
2005-10-20 |
Curis, Inc. |
Rna interference modulators of hedgehog signaling and uses thereof
|
US8268324B2
(en)
|
2004-03-29 |
2012-09-18 |
Galpharma Co., Ltd. |
Modified galectin 9 proteins and use thereof
|
US20050244869A1
(en)
|
2004-04-05 |
2005-11-03 |
Brown-Driver Vickie L |
Modulation of transthyretin expression
|
US8394947B2
(en)
|
2004-06-03 |
2013-03-12 |
Isis Pharmaceuticals, Inc. |
Positionally modified siRNA constructs
|
US7884086B2
(en)
|
2004-09-08 |
2011-02-08 |
Isis Pharmaceuticals, Inc. |
Conjugates for use in hepatocyte free uptake assays
|
US8697139B2
(en)
|
2004-09-21 |
2014-04-15 |
Frank M. Phillips |
Method of intervertebral disc treatment using articular chondrocyte cells
|
WO2006042112A2
(en)
|
2004-10-05 |
2006-04-20 |
California Institute Of Technology |
Aptamer regulated nucleic acids and uses thereof
|
EP1799243B1
(en)
|
2004-10-06 |
2015-07-15 |
University Of Rochester |
Treatment of pulmonary hypertension using an agent that inhibits a tissue factor pathway
|
US7833513B2
(en)
|
2004-12-03 |
2010-11-16 |
Rhode Island Hospital |
Treatment of Alzheimer's Disease
|
US8999944B2
(en)
|
2005-01-20 |
2015-04-07 |
University Of Rochester |
Thioredoxin interacting protein (TXNIP) as regulator of vascular function
|
AU2006213686A1
(en)
|
2005-02-09 |
2006-08-17 |
Avi Bio Pharma, Inc. |
Antisense composition and method for treating muscle atrophy
|
CN101163494A
(zh)
*
|
2005-02-23 |
2008-04-16 |
Uab研究基金会 |
烷基糖苷增强的接种
|
CA2597325A1
(en)
|
2005-03-10 |
2006-09-21 |
Genentech, Inc. |
Methods and compositions for modulating vascular integrity
|
WO2006105361A2
(en)
|
2005-03-31 |
2006-10-05 |
Calando Pharmaceuticals, Inc. |
Inhibitors of ribonucleotide reductase subunit 2 and uses thereof
|
US8734851B2
(en)
*
|
2005-04-29 |
2014-05-27 |
Wisconsin Alumni Research Foundation |
Localized delivery of nucleic acid by polyelectrolyte assemblies
|
UA95446C2
(xx)
|
2005-05-04 |
2011-08-10 |
Іллюміджен Байосайєнсіз, Інк. |
Мутації в генах oas1$мутаци в генах oas1
|
DE102005023993A1
(de)
*
|
2005-05-20 |
2006-11-23 |
TransMIT Gesellschaft für Technologietransfer mbH |
Nicht virales Vektorsystem zum Transport von Nukleinsäure in die Lunge
|
CA2630602A1
(en)
|
2005-11-21 |
2007-05-31 |
Isis Pharmaceuticals, Inc. |
Modulation of eif4e-bp2 expression
|
CA2566267A1
(en)
*
|
2005-12-09 |
2007-06-09 |
University Health Network |
Thymidylate kinase mutants and uses thereof
|
WO2007067733A2
(en)
*
|
2005-12-09 |
2007-06-14 |
Massachusetts Institute Of Technology |
Compositions and methods to monitor rna delivery to cells
|
US20090068158A1
(en)
*
|
2005-12-09 |
2009-03-12 |
Medin Jeffrey A |
Thymidylate kinase mutants and uses thereof
|
PT2161038E
(pt)
|
2006-01-26 |
2014-03-10 |
Isis Pharmaceuticals Inc |
Composições e suas utilizações dirigidas à huntingtina
|
AU2007215275B2
(en)
*
|
2006-02-10 |
2013-01-17 |
The Regents Of The University Of California |
Transducible delivery of siRNA by dsRNA binding domain fusions to PTD/CPPS
|
EP2495327B1
(en)
|
2006-03-03 |
2016-09-28 |
ProMIS Neurosciences Inc. |
Methods and compositions to treat and detect misfolded-SOD1 mediated diseases
|
US7718193B2
(en)
*
|
2006-03-16 |
2010-05-18 |
University Of Washington |
Temperature- and pH-responsive polymer compositions
|
WO2007126455A2
(en)
|
2006-04-05 |
2007-11-08 |
Genentech, Inc. |
Method for using boc/cdo to modulate hedgehog signaling
|
BRPI0711182A2
(pt)
|
2006-05-03 |
2011-08-23 |
Baltic Technology Dev |
agentes anti-sentido combinando base fortemente ligada-oligonucleotìdeo modificado e nuclease artificial
|
WO2008020335A2
(en)
|
2006-06-09 |
2008-02-21 |
Novartis Ag |
Immunogenic compositions for streptococcus agalactiae
|
EP2046964B1
(en)
*
|
2006-07-12 |
2018-07-04 |
The Regents of The University of California |
Transducible delivery of nucleic acids by reversible phosphotriester charge neutralization protecting groups
|
WO2008011473A2
(en)
|
2006-07-19 |
2008-01-24 |
Isis Pharmaceuticals, Inc. |
Compositions and their uses directed to hbxip
|
US8017109B2
(en)
*
|
2006-08-18 |
2011-09-13 |
Roche Madison Inc. |
Endosomolytic poly(acrylate) polymers
|
MX2009001207A
(es)
*
|
2006-08-18 |
2009-02-11 |
Hoffmann La Roche |
Policonjugados para el suministro in vivo de polinucleotidos.
|
WO2008030604A2
(en)
|
2006-09-08 |
2008-03-13 |
Rhode Island Hospital |
Treatment, prevention, and reversal of alcohol-induced brain disease
|
ES2399147T3
(es)
|
2006-09-08 |
2013-03-26 |
Rhode Island Hospital |
Tratamiento, prevención y reversión de una enfermedad hepática alcohólica
|
WO2008058291A2
(en)
|
2006-11-09 |
2008-05-15 |
California Institute Of Technology |
Modular aptamer-regulated ribozymes
|
CA2671850A1
(en)
*
|
2006-12-08 |
2008-06-19 |
Massachusetts Institute Of Technology |
Delivery of nanoparticles and/or agents to cells
|
WO2008086807A2
(en)
*
|
2007-01-19 |
2008-07-24 |
Exiqon A/S |
Mediated cellular delivery of lna oligonucleotides
|
US8834918B2
(en)
*
|
2007-01-22 |
2014-09-16 |
Wisconsin Alumni Research Foundation |
Modified multilayered film
|
US20080176958A1
(en)
|
2007-01-24 |
2008-07-24 |
Insert Therapeutics, Inc. |
Cyclodextrin-based polymers for therapeutics delivery
|
US20100093836A1
(en)
|
2007-01-29 |
2010-04-15 |
Isis Pharmaceuticals, Inc |
Compounds and methods for modulating protein expression
|
US7875431B2
(en)
|
2007-02-22 |
2011-01-25 |
Genentech, Inc. |
Methods for detecting inflammatory bowel disease
|
US7981688B2
(en)
|
2007-03-08 |
2011-07-19 |
University Of Washington |
Stimuli-responsive magnetic nanoparticles and related methods
|
US8673859B2
(en)
|
2007-03-20 |
2014-03-18 |
New York University |
GM-CSF cosmeceutical compositions and methods of use thereof
|
CA2584494A1
(en)
*
|
2007-03-27 |
2008-09-27 |
Jeffrey A. Medin |
Vector encoding therapeutic polypeptide and safety elements to clear transduced cells
|
EP3293266A1
(en)
|
2007-05-04 |
2018-03-14 |
University Health Network |
Il-12 immunotherapy for cancer
|
US20090082217A1
(en)
*
|
2007-07-16 |
2009-03-26 |
California Institute Of Technology |
Selection of nucleic acid-based sensor domains within nucleic acid switch platform
|
US8367815B2
(en)
*
|
2007-08-28 |
2013-02-05 |
California Institute Of Technology |
Modular polynucleotides for ligand-controlled regulatory systems
|
US20120165387A1
(en)
|
2007-08-28 |
2012-06-28 |
Smolke Christina D |
General composition framework for ligand-controlled RNA regulatory systems
|
US8865667B2
(en)
*
|
2007-09-12 |
2014-10-21 |
California Institute Of Technology |
Higher-order cellular information processing devices
|
AU2008307482B2
(en)
|
2007-10-02 |
2012-07-12 |
Amgen Inc. |
Increasing erythropoietin using nucleic acids hybridizable to micro-RNA and precursors thereof
|
US20090105375A1
(en)
*
|
2007-10-09 |
2009-04-23 |
Lynn David M |
Ultrathin Multilayered Films for Controlled Release of Anionic Reagents
|
US9029524B2
(en)
*
|
2007-12-10 |
2015-05-12 |
California Institute Of Technology |
Signal activated RNA interference
|
EP2077119A1
(de)
*
|
2007-12-21 |
2009-07-08 |
Apeiron Biologics Forschungs- und Entwicklungsgesellschaft M.B.H. |
Behandlung von Fibrosen und Lebererkrankungen
|
US8344116B2
(en)
*
|
2008-03-17 |
2013-01-01 |
Case Western Reserve University |
Polymers and complexes for delivery of nucleic acids to intracellular targets
|
US8568709B2
(en)
|
2008-03-20 |
2013-10-29 |
University Health Network |
Thymidylate kinase fusions and uses thereof
|
AU2009232355A1
(en)
|
2008-04-04 |
2009-10-08 |
Calando Pharmaceuticals, Inc. |
Compositions and use of EPAS1 inhibitors
|
GB2459436A
(en)
*
|
2008-04-08 |
2009-10-28 |
Henderson Morley Plc |
Vaccine adjuvant
|
US8324333B2
(en)
*
|
2008-06-05 |
2012-12-04 |
Wisconsin Alumni Research Foundation |
Anionic charge-dynamic polymers for release of cationic agents
|
WO2010008582A2
(en)
|
2008-07-18 |
2010-01-21 |
Rxi Pharmaceuticals Corporation |
Phagocytic cell drug delivery system
|
BRPI0912923A8
(pt)
|
2008-08-25 |
2017-12-12 |
Ionis Pharmaceuticals Inc |
Composto que consiste de um oligonucleotídeo modificadpo composto de 12-30 nucleosídeos ligados, compostos que compreende um oligonucleotídeo modificado que compreende pelo menos 12 nucleosídeos ligados, composto que compreende um oligonucleotídeo modificado que compreende nucleosídeos ligados, e, uso de um composto
|
WO2010033246A1
(en)
|
2008-09-22 |
2010-03-25 |
Rxi Pharmaceuticals Corporation |
Rna interference in skin indications
|
JP6091752B2
(ja)
|
2008-12-04 |
2017-03-08 |
クルナ・インコーポレーテッド |
Epoに対する天然アンチセンス転写物の抑制によるエリスロポエチン(epo)関連疾患の治療
|
KR101840618B1
(ko)
|
2008-12-04 |
2018-03-20 |
큐알엔에이, 인크. |
종양 억제 유전자에 대한 천연 안티센스 전사체의 억제에 의해 종양 억제 유전자 관련된 질환의 치료
|
US20110237649A1
(en)
|
2008-12-04 |
2011-09-29 |
Opko Curna, Llc |
Treatment of sirtuin 1 (sirt1) related diseases by inhibition of natural antisense transcript to sirtuin 1
|
US9493774B2
(en)
|
2009-01-05 |
2016-11-15 |
Rxi Pharmaceuticals Corporation |
Inhibition of PCSK9 through RNAi
|
ES2560107T3
(es)
|
2009-02-12 |
2016-02-17 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con el factor neurotrófico derivado de cerebro (BDNF) por inhibición de transcrito antisentido natural para BDNF
|
JP6066035B2
(ja)
|
2009-02-12 |
2017-01-25 |
クルナ・インコーポレーテッド |
グリア細胞由来神経栄養因子(gdnf)関連疾病の、gdnfに対する天然アンチセンス転写物の抑制による治療
|
US8329882B2
(en)
|
2009-02-18 |
2012-12-11 |
California Institute Of Technology |
Genetic control of mammalian cells with synthetic RNA regulatory systems
|
US20110319317A1
(en)
|
2009-03-04 |
2011-12-29 |
Opko Curna, Llc |
Treatment of sirtuin 1 (sirt1) related diseases by inhibition of natural antisense transcript to sirt1
|
US9464287B2
(en)
|
2009-03-16 |
2016-10-11 |
Curna, Inc. |
Treatment of nuclear factor (erythroid-derived 2)-like 2 (NRF2) related diseases by inhibition of natural antisense transcript to NRF2
|
WO2010107740A2
(en)
|
2009-03-17 |
2010-09-23 |
Curna, Inc. |
Treatment of delta-like 1 homolog (dlk1) related diseases by inhibition of natural antisense transcript to dlk1
|
US8772238B2
(en)
|
2009-03-18 |
2014-07-08 |
The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Use of ixolaris, a tissue factor inhibitor, for the treatment of cancer
|
US9145555B2
(en)
|
2009-04-02 |
2015-09-29 |
California Institute Of Technology |
Integrated—ligand-responsive microRNAs
|
EP3248618A1
(en)
|
2009-04-22 |
2017-11-29 |
Massachusetts Institute Of Technology |
Innate immune suppression enables repeated delivery of long rna molecules
|
DK2424987T3
(en)
|
2009-05-01 |
2018-02-26 |
Curna Inc |
TREATMENT OF HEMOGLOBIN (HBF / HBG) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPTION TO HBF / HBG
|
CN102803492B
(zh)
|
2009-05-06 |
2016-06-29 |
库尔纳公司 |
通过抑制针对三重四脯氨酸(ttp)的天然反义转录物来治疗ttp相关疾病
|
CN102459596B
(zh)
|
2009-05-06 |
2016-09-07 |
库尔纳公司 |
通过针对脂质转运和代谢基因的天然反义转录物的抑制治疗脂质转运和代谢基因相关疾病
|
JP5922017B2
(ja)
|
2009-05-18 |
2016-05-24 |
クルナ・インコーポレーテッド |
リプログラミング因子に対する天然アンチセンス転写物の抑制によるリプログラミング因子関連疾患の治療
|
JP2012527248A
(ja)
|
2009-05-22 |
2012-11-08 |
クルナ・インコーポレーテッド |
転写因子e3(tfe3)に対する天然アンチセンス転写物の阻害によるtfe3およびインスリン受容体基質2(irs2)関連疾患の処置
|
ES2618576T3
(es)
|
2009-05-28 |
2017-06-21 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con un gen antivírico mediante la inhibición de una transcripción antisentido natural a un gen antivírico
|
JP5917394B2
(ja)
|
2009-06-10 |
2016-05-11 |
ニューヨーク・ユニバーシティ |
病理学的タウタンパク質の免疫学的標的化方法
|
US8426214B2
(en)
*
|
2009-06-12 |
2013-04-23 |
University Of Washington |
System and method for magnetically concentrating and detecting biomarkers
|
ES2620960T3
(es)
|
2009-06-16 |
2017-06-30 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con un gen de colágeno mediante la inhibición de un transcrito antisentido natural a un gen de colágeno
|
EP2443238B1
(en)
|
2009-06-16 |
2017-03-22 |
CuRNA, Inc. |
Treatment of paraoxonase 1 (pon1) related diseases by inhibition of natural antisense transcript to pon1
|
JP6073133B2
(ja)
|
2009-06-24 |
2017-02-01 |
クルナ・インコーポレーテッド |
腫瘍壊死因子受容体2(tnfr2)に対する天然アンチセンス転写物の抑制によるtnfr2関連疾患の治療
|
ES2583691T3
(es)
|
2009-06-26 |
2016-09-21 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con un gen del síndrome de Down mediante la inhibición de una transcripción antisentido natural a un gen del síndrome de Down
|
EP2462229B1
(en)
|
2009-08-05 |
2016-05-11 |
CuRNA, Inc. |
Treatment of insulin gene (ins) related diseases by inhibition of natural antisense transcript to an insulin gene (ins)
|
CN102482671B
(zh)
|
2009-08-25 |
2017-12-01 |
库尔纳公司 |
通过抑制‘含有iq模体的gtp酶激活蛋白’(iqgap)的天然反义转录物而治疗iqgap相关疾病
|
US9321823B2
(en)
|
2009-09-02 |
2016-04-26 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
AU2010306940A1
(en)
|
2009-10-12 |
2012-06-07 |
Smith, Larry |
Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro
|
WO2011050194A1
(en)
|
2009-10-22 |
2011-04-28 |
Genentech, Inc. |
Methods and compositions for modulating hepsin activation of macrophage-stimulating protein
|
WO2011052804A1
(en)
*
|
2009-10-30 |
2011-05-05 |
Tokyo University Of Science Educational Foundation Administrative Organization |
Method of delivering agent into target cell
|
US20120244169A1
(en)
|
2009-11-06 |
2012-09-27 |
Fibrogen, Inc. |
Treatment for Radiation-Induced Disorders
|
US20110117668A1
(en)
*
|
2009-11-09 |
2011-05-19 |
University Of Washington Through Its Center For Commercialization |
Self-powered smart diagnostic devices
|
US9080933B2
(en)
|
2009-11-09 |
2015-07-14 |
University Of Washington Through Its Center For Commercialization |
Stimuli-responsive polymer diagnostic assay comprising magnetic nanoparticles and capture conjugates
|
JP6220126B2
(ja)
*
|
2009-11-23 |
2017-10-25 |
セルリアン・ファーマ・インコーポレイテッド |
治療的送達のためのシクロデキストリンに基づく重合体
|
PE20121584A1
(es)
|
2009-11-30 |
2012-11-29 |
Genentech Inc |
Composiciones y metodos para el diagnostico y el tratamiento de tumores
|
AU2010329847A1
(en)
|
2009-12-11 |
2012-07-26 |
Genecode As |
Methods of facilitating neural cell survival using GDNF family ligand (GFL) mimetics or RET signaling pathway activators
|
CN102712927B
(zh)
|
2009-12-16 |
2017-12-01 |
库尔纳公司 |
通过抑制膜结合转录因子肽酶,位点1(mbtps1)的天然反义转录物来治疗mbtps1相关疾病
|
NO2516648T3
(xx)
|
2009-12-23 |
2018-04-07 |
|
|
CN102781480B
(zh)
|
2009-12-23 |
2018-07-27 |
库尔纳公司 |
通过抑制解偶联蛋白2(ucp2)的天然反义转录物而治疗ucp2相关疾病
|
KR101838305B1
(ko)
|
2009-12-29 |
2018-03-13 |
큐알엔에이, 인크. |
NRF1(Nuclear Respiratory Factor 1)에 대한 천연 안티센스 전사체의 억제에 의한 핵 호흡 인자 1 관련된 질환의 치료
|
ES2585829T3
(es)
|
2009-12-29 |
2016-10-10 |
Curna, Inc. |
Tratamiento de las enfermedades relacionadas con la proteína tumoral 63 (p63) por inhibición de transcripción antisentido natural a p63
|
RU2611187C2
(ru)
|
2010-01-04 |
2017-02-21 |
Курна, Инк. |
Лечение заболеваний, связанных с интерферон-регуляторным фактором 8 (irf8), путем ингибирования природного антисмыслового транскрипта к irf8
|
JP5963680B2
(ja)
|
2010-01-06 |
2016-08-03 |
カッパーアールエヌエー,インコーポレイテッド |
膵臓発生遺伝子に対する天然アンチセンス転写物の阻害による膵臓発生遺伝子疾患の治療
|
JP6027893B2
(ja)
|
2010-01-11 |
2016-11-16 |
カッパーアールエヌエー,インコーポレイテッド |
性ホルモン結合グロブリン(shbg)に対する天然アンチセンス転写物の阻害による性ホルモン結合グロブリン(shbg)関連疾患の治療
|
EP2525808A2
(en)
|
2010-01-19 |
2012-11-28 |
The Trustees Of Columbia University In The City Of New York |
Osteocalcin as a treatment for male reproductive disorders
|
JP5981850B2
(ja)
|
2010-01-25 |
2016-08-31 |
カッパーアールエヌエー,インコーポレイテッド |
RNaseH1に対する天然アンチセンス転写物の阻害によるRNaseH1関連疾患の治療
|
JP5976548B2
(ja)
|
2010-02-22 |
2016-08-23 |
カッパーアールエヌエー,インコーポレイテッド |
Pycr1に対する天然アンチセンス転写物の阻害によるピロリン−5−カルボン酸レダクターゼ1(pycr1)関連疾患の治療
|
EP2538981B1
(en)
|
2010-02-23 |
2017-12-20 |
F. Hoffmann-La Roche AG |
Compositions and methods for the diagnosis and treatment of tumor
|
AP3284A
(en)
|
2010-02-24 |
2015-05-31 |
Arrowhead Res Corp |
Compositions for targeted delivery of SIRNA
|
KR101900962B1
(ko)
|
2010-04-09 |
2018-09-20 |
큐알엔에이, 인크. |
섬유아세포 성장 인자 21 (fgf21)에 대한 자연 안티센스 전사체의 저해에 의한 섬유아세포 성장 인자 21 (fgf21) 관련된 질환의 치료
|
US8362207B2
(en)
|
2010-04-16 |
2013-01-29 |
Wake Forest University Health Sciences |
Multi-level specific targeting of cancer cells with IL-13
|
MX343559B
(es)
|
2010-04-29 |
2016-11-10 |
Ionis Pharmaceuticals Inc |
Modulacion de la expresion de transtiretina.
|
CN107988228B
(zh)
|
2010-05-03 |
2022-01-25 |
库尔纳公司 |
通过抑制沉默调节蛋白(sirt)的天然反义转录物而治疗沉默调节蛋白(sirt)相关疾病
|
WO2011139985A1
(en)
|
2010-05-03 |
2011-11-10 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
CN103429739B
(zh)
|
2010-05-12 |
2018-11-13 |
哥伦比亚大学纽约管理委员会 |
制备产生和分泌胰岛素的肠内分泌细胞的方法
|
TWI531370B
(zh)
|
2010-05-14 |
2016-05-01 |
可娜公司 |
藉由抑制par4天然反股轉錄本治療par4相關疾病
|
US8895528B2
(en)
|
2010-05-26 |
2014-11-25 |
Curna, Inc. |
Treatment of atonal homolog 1 (ATOH1) related diseases by inhibition of natural antisense transcript to ATOH1
|
US9057067B2
(en)
|
2010-07-10 |
2015-06-16 |
Kinki University |
Method for transfecting nucleic acid to cell and nucleic acid complex
|
CN103068982B
(zh)
|
2010-07-14 |
2017-06-09 |
库尔纳公司 |
通过抑制盘状大同系物(dlg)的天然反义转录物而治疗dlg相关疾病
|
US8481680B2
(en)
|
2010-10-05 |
2013-07-09 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
JP5986998B2
(ja)
|
2010-10-06 |
2016-09-06 |
カッパーアールエヌエー,インコーポレイテッド |
シアリダーゼ4(neu4)への天然アンチセンス転写物の阻害によるneu4関連疾患の治療
|
KR101865433B1
(ko)
|
2010-10-22 |
2018-07-13 |
큐알엔에이, 인크. |
알파-l 이두로니다아제 (idua)에 대한 자연 안티센스 전사체의 저해에 의한 idua 관련된 질환의 치료
|
CN103201387B
(zh)
|
2010-10-27 |
2018-02-02 |
库尔纳公司 |
通过抑制干扰素相关发育调节因子1(ifrd1)的天然反义转录物而治疗ifrd1相关疾病
|
WO2012061811A2
(en)
|
2010-11-05 |
2012-05-10 |
Fibrogen, Inc. |
Treatment method for lung remodeling diseases
|
CA2817712C
(en)
|
2010-11-12 |
2020-03-24 |
Georgetown University |
Immortalization of epithelial cells and methods of use
|
WO2012071238A2
(en)
|
2010-11-23 |
2012-05-31 |
Opko Curna Llc |
Treatment of nanog related diseases by inhibition of natural antisense transcript to nanog
|
US20130344053A1
(en)
|
2010-12-28 |
2013-12-26 |
University Of Rochester |
Methods of Modifying Insulin Signaling Using Biliverdin Reductase (BVR) and BVR Derived Peptides
|
HUE044178T2
(hu)
|
2011-02-02 |
2019-10-28 |
Excaliard Pharmaceuticals Inc |
Kötõszöveti növekedési faktort (CTGF) célzó antiszensz vegyületek keloidok vagy hipertrófiás hegek kezelési eljárásban történõ alkalmazásra
|
WO2012109495A1
(en)
|
2011-02-09 |
2012-08-16 |
Metabolic Solutions Development Company, Llc |
Cellular targets of thiazolidinediones
|
WO2012124688A1
(ja)
|
2011-03-14 |
2012-09-20 |
国立大学法人北海道大学 |
肺送達のためのベクター、導入剤及び使用
|
EP2697244B1
(en)
|
2011-04-13 |
2017-05-17 |
Ionis Pharmaceuticals, Inc. |
Antisense modulation of ptp1b expression
|
RU2620980C2
(ru)
|
2011-06-09 |
2017-05-30 |
Курна, Инк. |
Лечение заболеваний, связанных с фратаксином (fxn), путем ингибирования природного антисмыслового транскрипта fxn
|
EP2721156B1
(en)
|
2011-06-16 |
2016-12-21 |
Ionis Pharmaceuticals, Inc. |
Antisense modulation of fibroblast growth factor receptor 4 expression
|
PL2753346T3
(pl)
|
2011-09-07 |
2020-10-19 |
Mount Sinai School Of Medicine |
Ceramidaza i różnicowanie komórek
|
EP2758533B1
(en)
|
2011-09-20 |
2018-04-11 |
Ionis Pharmaceuticals, Inc. |
Antisense modulation of gcgr expression
|
US20130085139A1
(en)
|
2011-10-04 |
2013-04-04 |
Royal Holloway And Bedford New College |
Oligomers
|
KR20140084232A
(ko)
|
2011-10-25 |
2014-07-04 |
아이시스 파마수티컬즈 인코포레이티드 |
Gccr 발현의 안티센스 조절
|
KR20140136488A
(ko)
|
2012-03-15 |
2014-11-28 |
큐알엔에이, 인크. |
뇌 유래 신경영양 인자(bdnf)에 대한 천연 안티센스 전사체의 저해에 의한 뇌 유래 신경영양 인자(bdnf)관련 질환의 치료
|
US9950001B2
(en)
|
2012-08-20 |
2018-04-24 |
The Regents Of The University Of California |
Polynucleotides having bioreversible groups
|
US20160136159A1
(en)
|
2012-09-17 |
2016-05-19 |
Chemedest Ltd. |
Method for Treating Peripheral Neuropathy
|
WO2014055493A1
(en)
|
2012-10-02 |
2014-04-10 |
Cerulean Pharma Inc. |
Methods and systems for polymer precipitation and generation of particles
|
WO2014063155A1
(en)
|
2012-10-21 |
2014-04-24 |
University Of Rochester |
Thy1 (cd90) as a novel therapy to control adipose tissue accumulation
|
AU2013344375B2
(en)
|
2012-11-16 |
2017-09-14 |
Transposagen Biopharmaceuticals, Inc. |
Site-specific enzymes and methods of use
|
US10052364B2
(en)
|
2013-03-15 |
2018-08-21 |
The Trustees Of Columbia University In The City Of New York |
Osteocalcin as a treatment for cognitive disorders
|
US9822418B2
(en)
|
2013-04-22 |
2017-11-21 |
Icahn School Of Medicine At Mount Sinai |
Mutations in PDGFRB and NOTCH3 as causes of autosomal dominant infantile myofibromatosis
|
AU2014280847B2
(en)
|
2013-06-13 |
2019-07-04 |
Antisense Therapeutics Ltd |
Combination therapy
|
IL282239B2
(en)
|
2013-09-05 |
2023-10-01 |
Sarepta Therapeutics Inc |
Inclusion of exon 2 is induced by antisense in acid alpha-glucosidase
|
EP3047023B1
(en)
|
2013-09-19 |
2019-09-04 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Compositions and methods for inhibiting jc virus (jcv)
|
EP3068797B1
(en)
|
2013-11-11 |
2020-01-08 |
Wake Forest University Health Sciences |
Constructs for multi-valent targeting of tumors
|
WO2015116902A1
(en)
|
2014-01-31 |
2015-08-06 |
Genentech, Inc. |
G-protein coupled receptors in hedgehog signaling
|
CA2937539A1
(en)
|
2014-02-04 |
2015-08-13 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
WO2015171918A2
(en)
|
2014-05-07 |
2015-11-12 |
Louisiana State University And Agricultural And Mechanical College |
Compositions and uses for treatment thereof
|
EP3142673A4
(en)
|
2014-05-14 |
2018-01-03 |
Targlmmune Therapeutics AG |
Improved polyethyleneimine polyethyleneglycol vectors
|
US10729785B2
(en)
*
|
2014-05-19 |
2020-08-04 |
BioNTech SE |
Particles comprising protamine and RNA in combination with endosome destabilizing agents
|
EP3160503B1
(en)
|
2014-06-26 |
2021-02-17 |
The Trustees of Columbia University in the City of New York |
Inhibition of serotonin expression in gut enteroendocrine cells results in conversion to insulin-positive cells
|
EP3169310A1
(en)
|
2014-07-15 |
2017-05-24 |
Life Technologies Corporation |
Compositions with lipid aggregates and methods for efficient delivery of molecules to cells
|
WO2016033424A1
(en)
|
2014-08-29 |
2016-03-03 |
Genzyme Corporation |
Methods for the prevention and treatment of major adverse cardiovascular events using compounds that modulate apolipoprotein b
|
US11191811B2
(en)
|
2014-11-19 |
2021-12-07 |
The Trustees Of Columbia University In The City Of New York |
Osteocalcin as a treatment for frailty associated with aging
|
WO2016100716A1
(en)
|
2014-12-18 |
2016-06-23 |
Vasant Jadhav |
Reversirtm compounds
|
MA41795A
(fr)
|
2015-03-18 |
2018-01-23 |
Sarepta Therapeutics Inc |
Exclusion d'un exon induite par des composés antisens dans la myostatine
|
JP6873052B2
(ja)
|
2015-06-01 |
2021-05-19 |
サレプタ セラピューティクス,インコーポレイテッド |
Vii型コラーゲンにおけるアンチセンス誘導エクソン排除
|
CA2989827A1
(en)
|
2015-06-17 |
2016-12-22 |
Poseida Therapeutics, Inc. |
Compositions and methods for directing proteins to specific loci in the genome
|
WO2017058881A1
(en)
|
2015-09-28 |
2017-04-06 |
The Trustees Of Columbia University In The City Of New York |
Use of pentoxifylline with immune checkpoint-blockade therapies for the treatment of melanoma
|
JP2018530560A
(ja)
|
2015-10-09 |
2018-10-18 |
サレプタ セラピューティクス, インコーポレイテッド |
デュシェンヌ型筋ジストロフィーおよび関連障害の処置のための組成物および方法
|
US11273151B2
(en)
|
2015-11-04 |
2022-03-15 |
Icahn School Of Medicine At Mount Sinai |
Methods of treating tumors and cancer, and identifying candidate subjects for such treatment
|
AU2016349954B2
(en)
|
2015-11-05 |
2022-08-25 |
Antisense Therapeutics Ltd |
Mobilizing leukemia cells
|
WO2017106926A1
(en)
|
2015-12-23 |
2017-06-29 |
Queensland University Of Technology |
Nucleic acid oligomers and uses therefor
|
CA3019952A1
(en)
|
2016-02-04 |
2017-08-10 |
Curis, Inc. |
Mutant smoothened and methods of using the same
|
SG11201808964PA
(en)
|
2016-04-18 |
2018-11-29 |
Sarepta Therapeutics Inc |
Antisense oligomers and methods of using the same for treating diseases associated with the acid alpha-glucosidase gene
|
WO2017189730A1
(en)
|
2016-04-26 |
2017-11-02 |
Icahn School Of Medicine At Mount Sinai |
Treatment of hippo pathway mutant tumors and methods of identifying subjects as candidates for treatment
|
CN110023321A
(zh)
|
2016-08-17 |
2019-07-16 |
索尔斯蒂斯生物有限公司 |
多核苷酸构建体
|
US10994025B2
(en)
|
2017-05-12 |
2021-05-04 |
Massachusetts Institute Of Technology |
Argonaute protein-double stranded RNA complexes and uses related thereto
|
WO2019006455A1
(en)
|
2017-06-30 |
2019-01-03 |
Solstice Biologics, Ltd. |
AUXILIARIES OF CHIRAL PHOSPHORAMIDITIS AND METHODS OF USE THEREOF
|
WO2019055460A1
(en)
|
2017-09-13 |
2019-03-21 |
The Children's Medical Center Corporation |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF TRANSPOSON-ASSOCIATED DISEASES
|
EP3697910A4
(en)
|
2017-10-18 |
2021-07-14 |
Sarepta Therapeutics, Inc. |
ANTISENSE OLIGOMERIC COMPOUNDS
|
WO2019126578A1
(en)
|
2017-12-20 |
2019-06-27 |
Poseida Therapeutics, Inc. |
Compositions and methods for directing proteins to specific loci in the genome
|
KR20200141470A
(ko)
|
2018-04-06 |
2020-12-18 |
칠드런'즈 메디컬 센터 코포레이션 |
체세포 재프로그래밍 및 각인의 조정을 위한 조성물 및 방법
|
EP4326873A1
(en)
|
2021-04-22 |
2024-02-28 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating cancer
|
WO2024168010A2
(en)
|
2023-02-09 |
2024-08-15 |
Alnylam Pharmaceuticals, Inc. |
Reversir molecules and methods of use thereof
|