FI935128A - SAMTIDIGA MAONGFALDIGA BESTAEMNINGAR - Google Patents

SAMTIDIGA MAONGFALDIGA BESTAEMNINGAR Download PDF

Info

Publication number
FI935128A
FI935128A FI935128A FI935128A FI935128A FI 935128 A FI935128 A FI 935128A FI 935128 A FI935128 A FI 935128A FI 935128 A FI935128 A FI 935128A FI 935128 A FI935128 A FI 935128A
Authority
FI
Finland
Prior art keywords
samtidiga
maongfaldiga
bestaemningar
fpa
entails
Prior art date
Application number
FI935128A
Other languages
Finnish (fi)
Other versions
FI935128A0 (en
Inventor
W Peter Hansen
Original Assignee
Sienna Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sienna Biotech Inc filed Critical Sienna Biotech Inc
Publication of FI935128A0 publication Critical patent/FI935128A0/en
Publication of FI935128A publication Critical patent/FI935128A/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4905Determining clotting time of blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N2015/0092Monitoring flocculation or agglomeration
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N2021/4704Angular selective
    • G01N2021/4707Forward scatter; Low angle scatter
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/808Optical sensing apparatus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/805Optical property

Abstract

A particle agglutination-based, stable kinetic method for simultaneously determining the concentrations of multiple analytes in a single fluid sample with the addition of a single reagent, that entails the use of a novel high resolution sheath flow cell, a novel optical flow particle analyzer (FPA), and unidirectional low angle forward light scattering from multiply-sized or refractive indexed, differently coated particles and their aggregates.
FI935128A 1991-05-20 1993-11-19 SAMTIDIGA MAONGFALDIGA BESTAEMNINGAR FI935128A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70230291A 1991-05-20 1991-05-20
US07/883,574 US5286452A (en) 1991-05-20 1992-05-15 Simultaneous multiple assays
PCT/US1992/004155 WO1992021024A1 (en) 1991-05-20 1992-05-19 Simultaneous multiple assays

Publications (2)

Publication Number Publication Date
FI935128A0 FI935128A0 (en) 1993-11-19
FI935128A true FI935128A (en) 1993-11-19

Family

ID=27106944

Family Applications (1)

Application Number Title Priority Date Filing Date
FI935128A FI935128A (en) 1991-05-20 1993-11-19 SAMTIDIGA MAONGFALDIGA BESTAEMNINGAR

Country Status (16)

Country Link
US (2) US5286452A (en)
EP (1) EP0585369B1 (en)
JP (1) JPH06507972A (en)
KR (1) KR100215348B1 (en)
AT (1) ATE169116T1 (en)
AU (1) AU656399B2 (en)
CA (1) CA2103455A1 (en)
DE (1) DE69226433T2 (en)
DK (1) DK0585369T3 (en)
ES (1) ES2120448T3 (en)
FI (1) FI935128A (en)
IE (1) IE921598A1 (en)
NO (1) NO934205L (en)
RU (1) RU2111488C1 (en)
TW (1) TW197940B (en)
WO (1) WO1992021024A1 (en)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6200820B1 (en) * 1992-12-22 2001-03-13 Sienna Biotech, Inc. Light scatter-based immunoassay
TW239881B (en) * 1992-12-22 1995-02-01 Sienna Biotech Inc
US5503982A (en) * 1993-09-30 1996-04-02 Research Corporation Technologies, Inc. Detection of an acute myocardial infarction in a patient
US5547833A (en) * 1994-01-04 1996-08-20 Intracel Corporation Radial flow assay, delivering member, test kit, and methods
US5561045A (en) * 1994-01-04 1996-10-01 Intracel Corporation Detection reagent, article, and immunoassay method
US5485270A (en) * 1994-07-25 1996-01-16 General Signal Corporation Dynamic light scattering microvolume cell assembly for continuous flow dialysis
US6951716B2 (en) * 1995-03-13 2005-10-04 Mark Hechinger Anti-platelet immunoglobulin bead positive control
US6159748A (en) * 1995-03-13 2000-12-12 Affinitech, Ltd Evaluation of autoimmune diseases using a multiple parameter latex bead suspension and flow cytometry
US20030008410A1 (en) * 1995-03-13 2003-01-09 Hechinger Mark K. Immunoassay apparatus, kit and methods
AU3094195A (en) * 1995-07-10 1997-02-10 Donald L. Kramer Light transmittance type analytical system, variable transmittance optical component, and test device
US5736330A (en) * 1995-10-11 1998-04-07 Luminex Corporation Method and compositions for flow cytometric determination of DNA sequences
US5981180A (en) * 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
DE69638321D1 (en) 1995-10-11 2011-03-03 Luminex Corp SIMULTANEOUS MULTI-ANALYSIS OF CLINICAL SAMPLES
US5817519A (en) * 1995-12-28 1998-10-06 Bayer Corporation Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
US6025201A (en) * 1995-12-28 2000-02-15 Bayer Corporation Highly sensitive, accurate, and precise automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
US5851777A (en) * 1996-02-05 1998-12-22 Dade Behring Inc. Homogeneous sol-sol assay
US5649576A (en) * 1996-02-26 1997-07-22 Pharmacopeia, Inc. Partitioning device
BR9710836A (en) 1996-04-25 2000-10-24 Spectrametrix Inc Analyte assay using particle marks
US6586193B2 (en) * 1996-04-25 2003-07-01 Genicon Sciences Corporation Analyte assay using particulate labels
US6449562B1 (en) 1996-10-10 2002-09-10 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
US5858648A (en) * 1996-11-04 1999-01-12 Sienna Biotech, Inc. Assays using reference microparticles
US6002788A (en) * 1997-09-24 1999-12-14 Compucyte Corporation Method and device for rendering cells observable with laser scanning cytometry
EP0919568A1 (en) 1997-12-01 1999-06-02 Sorin Diagnostics S.r.l. Escape mutant of the surface antigen of hepatitis B virus
AU2322099A (en) * 1998-01-16 1999-08-02 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
ITTO980473A1 (en) * 1998-06-02 1999-12-02 Sorin Diagnostics S R L NEW PROCEDURE FOR THE DETECTION OF ANTIBODIES AND / OR ISOTYPES OF SPECIFIC ANTIBODIES FOR AT LEAST TWO DIFFERENT PHASES OF AN INFECTION
US6315952B1 (en) 1998-10-05 2001-11-13 The University Of New Mexico Plug flow cytometry for high throughput screening and drug discovery
JP2000214070A (en) * 1999-01-21 2000-08-04 Sysmex Corp Sheath flow cell and hemanalyzer using the same
US6480276B1 (en) 1999-07-13 2002-11-12 Clemson University Enhanced photon-migration methods for particle sizing in concentrated suspensions
US6890487B1 (en) 1999-09-30 2005-05-10 Science & Technology Corporation ©UNM Flow cytometry for high throughput screening
US7416903B2 (en) * 1999-09-30 2008-08-26 Stc.Unm Wavy interface mixer
US6392327B1 (en) 2000-03-29 2002-05-21 James L. Sackrison Sonic transducer and feedback control method thereof
US20020028434A1 (en) * 2000-09-06 2002-03-07 Guava Technologies, Inc. Particle or cell analyzer and method
WO2002068932A2 (en) * 2001-02-23 2002-09-06 Genicon Sciences Corporation Methods for providing extended dynamic range in analyte assays
DE10122806A1 (en) * 2001-05-10 2002-11-14 Holger Kiesewetter Method for the detection of blood cell antigens and antibodies directed against them
WO2004010099A2 (en) * 2001-05-16 2004-01-29 Burstein Technologies, Inc. Variable sampling for rendering pixelization of analysis results in optical bio-disc assembly
WO2003021853A2 (en) * 2001-09-05 2003-03-13 Genicon Sciences Corporation Apparatus for reading signals generated from resonance light scattered particle labels
US20030109067A1 (en) 2001-12-06 2003-06-12 Immunetech, Inc. Homogeneous immunoassays for multiple allergens
FR2834796B1 (en) * 2002-01-11 2006-01-06 Biomedical Diagnostics Sa PROCESS FOR OBTAINING A SINGLE CALIBRATION SYSTEM APPLIED TO MULTIPARAMETRIC ASSAYS OF BIOLOGICAL SAMPLES, IMMUNOLOGICAL REAGENT PREPARED THEREFOR, AND ASSAY METHOD
DE60308259T2 (en) * 2002-05-22 2007-04-05 Sysmex Corp. Immunological methods, devices and reagents
US7560239B2 (en) * 2002-06-04 2009-07-14 Lin-Zhi International Inc. Homogeneous enzyme immunoassay for simultaneous detection of multiple analytes
WO2004031756A1 (en) * 2002-10-02 2004-04-15 Airadvice, Inc. Method and apparatus for particle sizing
US7016791B2 (en) * 2002-10-02 2006-03-21 Airadvice, Inc. Particle sizing refinement system
CN100357737C (en) * 2002-11-12 2007-12-26 松下电器产业株式会社 Specific combination reaction analyzing method, analyzer and used kit
US7053783B2 (en) 2002-12-18 2006-05-30 Biovigilant Systems, Inc. Pathogen detector system and method
WO2005029078A1 (en) * 2003-09-17 2005-03-31 Guava Technologies, Inc. Compositions and methods for analysis of target analytes
US20070054405A1 (en) * 2003-10-23 2007-03-08 Ortho-Clinical Diagnostics, Inc. Patient sample classification based upon low angle light scattering
US20050141843A1 (en) * 2003-12-31 2005-06-30 Invitrogen Corporation Waveguide comprising scattered light detectable particles
US7430046B2 (en) * 2004-07-30 2008-09-30 Biovigilant Systems, Inc. Pathogen and particle detector system and method
KR101283071B1 (en) * 2005-07-15 2013-07-05 바이오비질런트 시스템즈 인코포레이티드 Pathogen and particle detector system and method
US7851229B2 (en) * 2006-05-12 2010-12-14 Primus Corporation Two-phase optical assay with unitized container and double or single sensor systems
US7859664B2 (en) * 2007-09-13 2010-12-28 Brightwell Technologies Inc. Plurality of samples and method for selecting a target sample therefrom
US8628976B2 (en) 2007-12-03 2014-01-14 Azbil BioVigilant, Inc. Method for the detection of biologic particle contamination
FR2928656B1 (en) * 2008-03-14 2011-08-26 Biomerieux Sa METHOD FOR REAL - TIME DETECTION OF MICROORGANISMS IN A LIQUID CULTURE MEDIUM BY AGGLUTINATION.
US8154273B2 (en) * 2008-10-10 2012-04-10 Beckman Coulter, Inc. Detecting and handling coincidence in particle analysis
WO2010135627A1 (en) 2009-05-21 2010-11-25 Intellicyt System and method for separating samples in a continuous flow
US9752964B1 (en) 2009-06-22 2017-09-05 Stc.Unm Flow cytometry apparatus pulling sample stream through observation chamber
KR101139954B1 (en) * 2010-01-28 2012-04-30 서울대학교산학협력단 Apparatus and method for measuring intensity of particle immunoagglutination reaction
WO2011149526A2 (en) 2010-05-25 2011-12-01 Arryx, Inc. Methods and apparatuses for detection of positional freedom of particles in biological and chemical analyses and applications in immunodiagnostics
EP2466292B1 (en) * 2010-10-29 2017-12-13 F. Hoffmann-La Roche AG System for performing scattering and absorbance assays
US20130000738A1 (en) * 2011-02-28 2013-01-03 Pathogenetix, Inc. Method and system for transferring and/or concentrating a sample
DE102013212539B4 (en) * 2013-06-27 2015-07-23 Carl Von Ossietzky Universität Oldenburg Method and apparatus for analysis
EP3436798B1 (en) * 2016-03-30 2021-10-13 Sintrol Oy Method for measuring the properties of particles in a medium and a device for measuring the properties of particles in a flue gas
US11009504B2 (en) * 2017-01-31 2021-05-18 Maxim Integrated Products. Inc. System and method for performing an assay with sub-pixel sized beads

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4027971A (en) * 1973-01-08 1977-06-07 Philip Kolman Method of simultaneously counting blood cells
US4184849A (en) * 1977-12-05 1980-01-22 Technicon Instruments Corporation Mixed agglutination
GB2045431B (en) * 1979-02-26 1983-04-20 Technicon Instr Immunoassay utilising two particulate reagents
US4766083A (en) * 1982-04-04 1988-08-23 Wako Pure Chemical Industries, Ltd. Method for the photometric determination of biological agglutination
US4521521A (en) * 1983-03-11 1985-06-04 E. I. Du Pont De Nemours And Company Particle reagent size distribution measurements for immunoassay
US4665020A (en) * 1984-05-30 1987-05-12 United States Department Of Energy Flow cytometer measurement of binding assays
US4963498A (en) * 1985-08-05 1990-10-16 Biotrack Capillary flow device
US4851329A (en) * 1986-06-06 1989-07-25 Massachusetts Institute Of Technology Immunoassay employing optical pulse particle size analysis
US4850707A (en) * 1986-06-06 1989-07-25 Massachusetts Institute Of Technology Optical pulse particle size analyzer
US4765737A (en) * 1987-03-30 1988-08-23 Cornell Research Foundation Cell size measurements using light in flow cytometry and cell sorting
US4988630A (en) * 1987-04-27 1991-01-29 Hoffmann-La Roche Inc. Multiple beam laser instrument for measuring agglutination reactions
JPH0718879B2 (en) * 1988-02-15 1995-03-06 キヤノン株式会社 Specimen test method
US5162863A (en) * 1988-02-15 1992-11-10 Canon Kabushiki Kaisha Method and apparatus for inspecting a specimen by optical detection of antibody/antigen sensitized carriers
JP2667867B2 (en) * 1988-03-30 1997-10-27 東亜医用電子株式会社 Particle analyzer
NO164622C (en) * 1988-05-11 1990-10-24 Tore Lindmo BINAER IMMUNOMETRIC PARTICLE-BASED METHOD FOR MEASURING SPECIFIC SERUM ANTIGENS USING LIQUID FLOW MICROPHOTOMETRY AND A PREPARED TARGET SET UP THEREOF.
US5198369A (en) * 1990-04-25 1993-03-30 Canon Kabushiki Kaisha Sample measuring method using agglomeration reaction of microcarriers
US5144224A (en) * 1991-04-01 1992-09-01 Larsen Lawrence E Millimeter wave flow cytometer

Also Published As

Publication number Publication date
WO1992021024A1 (en) 1992-11-26
US5369037A (en) 1994-11-29
TW197940B (en) 1993-01-11
EP0585369A4 (en) 1996-07-10
IE921598A1 (en) 1992-12-02
AU2142092A (en) 1992-12-30
ES2120448T3 (en) 1998-11-01
DE69226433T2 (en) 1998-12-03
RU2111488C1 (en) 1998-05-20
DE69226433D1 (en) 1998-09-03
FI935128A0 (en) 1993-11-19
AU656399B2 (en) 1995-02-02
US5286452A (en) 1994-02-15
ATE169116T1 (en) 1998-08-15
NO934205D0 (en) 1993-11-19
EP0585369B1 (en) 1998-07-29
JPH06507972A (en) 1994-09-08
CA2103455A1 (en) 1992-11-21
EP0585369A1 (en) 1994-03-09
DK0585369T3 (en) 1999-04-26
NO934205L (en) 1993-11-19
KR100215348B1 (en) 1999-08-16

Similar Documents

Publication Publication Date Title
FI935128A (en) SAMTIDIGA MAONGFALDIGA BESTAEMNINGAR
RU93058382A (en) METHOD OF PARTICULAR AGGLUTINATION FOR SIMULTANEOUS RESEARCH OF SEVERAL ANALYTES IN ONE SAMPLE AND OPTICAL ANALYZER
US10876961B2 (en) Interactive variable pathlength device
Charlson et al. The direct measurement of atmospheric light scattering coefficient for studies of visibility and pollution
FR2106060A5 (en)
FI890591A (en) Sample vessels and apparatus for performing biological analyzes
ATE252229T1 (en) IMPROVEMENTS IN MEASUREMENT OF PARTICLE SIZE DISTRIBUTION
FI883868A0 (en) Sensor for biological, biochemical and chemical testing
US8922778B2 (en) Apparatus and method for increasing collection efficiency in capillary based flowcytometry
SE8100194L (en) FOTOMETERKUVETT
EP0672904A1 (en) A monolens for use in an optical detection system
IE40697L (en) Measuring particulate matter in suspension
ATE252230T1 (en) IMPROVEMENTS IN MEASUREMENT OF PARTICLE SIZE DISTRIBUTION
JPS5985945A (en) Liquid chromatograph device and its analysis method
CA2014388A1 (en) A device for determining the characteristics of particles in suspension in a liquid
EP0959353A3 (en) Calibrator for non-destructive transmission optical measuring apparatus
EP0383460A3 (en) Apparatus for measuring particles in liquid
Duling et al. A computerized system for densitometric analysis of the microcirculation
GB1303927A (en)
JPS57131036A (en) Light scattering type floating particle counting
Jakmunee et al. A low-cost light-scattering detector for the flow-injection nephelometric determination of sulfate
Bush et al. Computer simulation of light transmission through scattering and absorbing chromatographic media
JP3516536B2 (en) Receiving optical system and particle analyzer equipped with the receiving optical system
JPS6491036A (en) Measuring apparatus of particles in liquid
JPS5730951A (en) Blood analyzer