FI875770A0 - Analytiskt foerfarande foer att detektera och maeta nukleinsyror med en specifik sekvens. - Google Patents

Analytiskt foerfarande foer att detektera och maeta nukleinsyror med en specifik sekvens.

Info

Publication number
FI875770A0
FI875770A0 FI875770A FI875770A FI875770A0 FI 875770 A0 FI875770 A0 FI 875770A0 FI 875770 A FI875770 A FI 875770A FI 875770 A FI875770 A FI 875770A FI 875770 A0 FI875770 A0 FI 875770A0
Authority
FI
Finland
Prior art keywords
syror
nuclein
detector
specific sequence
analytical formulation
Prior art date
Application number
FI875770A
Other languages
English (en)
Other versions
FI875770A (fi
Inventor
Ranald Macdonald Sutherland
Peter Bromley
Bernard Gentile
Original Assignee
Battelle Memorial Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Memorial Institute filed Critical Battelle Memorial Institute
Publication of FI875770A publication Critical patent/FI875770A/fi
Publication of FI875770A0 publication Critical patent/FI875770A0/fi

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Plasma & Fusion (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
FI875770A 1986-05-05 1987-12-30 Analytiskt foerfarande foer att detektera och maeta nukleinsyror med en specifik sekvens. FI875770A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP86810201 1986-05-05
PCT/EP1987/000234 WO1987006956A1 (en) 1986-05-05 1987-05-02 Analytical method for detecting and measuring specifically sequenced nucleic acids

Publications (2)

Publication Number Publication Date
FI875770A FI875770A (fi) 1987-12-30
FI875770A0 true FI875770A0 (fi) 1987-12-30

Family

ID=8196461

Family Applications (1)

Application Number Title Priority Date Filing Date
FI875770A FI875770A0 (fi) 1986-05-05 1987-12-30 Analytiskt foerfarande foer att detektera och maeta nukleinsyror med en specifik sekvens.

Country Status (6)

Country Link
EP (1) EP0245206A1 (fi)
JP (1) JPH01500221A (fi)
AU (1) AU7583887A (fi)
DK (1) DK688A (fi)
FI (1) FI875770A0 (fi)
WO (1) WO1987006956A1 (fi)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2190189B (en) * 1986-03-21 1990-06-13 Block Myron Jacques Assay for polynucleotides
GB8612087D0 (en) * 1986-05-19 1986-06-25 Ici Plc Hybridisation probes
US6270961B1 (en) * 1987-04-01 2001-08-07 Hyseq, Inc. Methods and apparatus for DNA sequencing and DNA identification
US5089387A (en) * 1988-07-07 1992-02-18 Adeza Biomedical Corporation Dna probe diffraction assay and reagents
GB8827853D0 (en) * 1988-11-29 1988-12-29 Ares Serono Res & Dev Ltd Sensor for optical assay
GB9008261D0 (en) * 1990-04-11 1990-06-13 Ares Serono Res & Dev Ltd Method of improving assay sensitivity
GB8919411D0 (en) * 1989-08-25 1989-10-11 Amersham Int Plc Assay method
CA2039517C (en) * 1990-04-03 2006-11-07 David Segev Dna probe signal amplification
DE69125441T2 (de) * 1990-09-28 1997-11-06 Toshiba Kawasaki Kk Verfahren zum Gennachweis
US5776672A (en) * 1990-09-28 1998-07-07 Kabushiki Kaisha Toshiba Gene detection method
GB9119735D0 (en) * 1991-09-16 1991-10-30 Secr Defence Gene probe biosensor method
WO1993010266A1 (en) * 1991-11-22 1993-05-27 The United States Of America, Represented By The Secretary, United States Department Of Commerce Device and method for detection of compounds which intercalate with nucleic acids
EP0717779B1 (en) * 1992-04-06 2001-10-31 Abbott Laboratories Method and device for detection of nucleic acid or analyte using total internal reflectance
US7241569B2 (en) 1993-01-18 2007-07-10 Olympus Corporation Method and a device for the evaluation of biopolymer fitness
ATE164943T1 (de) 1993-01-18 1998-04-15 Evotec Biosystems Gmbh Verfahren und vorrichtung zur bewertung der fitness von biopolymeren
WO1995026416A1 (en) * 1994-03-25 1995-10-05 Research Corporation Technologies, Inc. Nucleic acid biosensor diagnostics
US5922534A (en) 1995-03-28 1999-07-13 Hewlett-Packard Company Dry biochemical assay plate and method for making the same
AU755913B2 (en) 1997-06-18 2003-01-02 Masad Damha Nucleic acid biosensor diagnostics
WO2000058507A1 (en) * 1999-03-30 2000-10-05 Solexa Ltd. Polynucleotide sequencing
US6960432B2 (en) * 1999-07-26 2005-11-01 Canon Kabushiki Kaisha Detection/quantification of targeted nucleotide chains, and detection/quantification of multi-stranded nucleotide chains by fluorescence
DE19947616C2 (de) * 1999-10-01 2003-05-28 Fraunhofer Ges Forschung Verfahren zur Bestimmung von Substanzen, wie z.B. DNA-Sequenzen, in einer Probe und Vorrichtung zur Durchführung des Verfahrens
DE10002566A1 (de) * 2000-01-21 2001-08-02 Fraunhofer Ges Forschung Verfahren und Einrichtung zur Bestimmung des Schmelzpunktes und/oder der Bindungskonstante von Substanzen, wie z. B. DNA-Sequenzen, in einer Probe
JP2003014647A (ja) * 2001-07-04 2003-01-15 System Instruments Kk プローブ物質を載せた導波路法による蛍光測定方法
US7687437B2 (en) 2001-07-13 2010-03-30 Nanosphere, Inc. Method for immobilizing molecules onto surfaces
DE102004027957A1 (de) * 2004-06-08 2005-12-29 Carl Zeiss Jena Gmbh Verfahren und Anordnung zur Untersuchung der Wechselwirkung von Biomolekülen
US9040305B2 (en) 2004-09-28 2015-05-26 Singulex, Inc. Method of analysis for determining a specific protein in blood samples using fluorescence spectrometry
US8685711B2 (en) 2004-09-28 2014-04-01 Singulex, Inc. Methods and compositions for highly sensitive detection of molecules
US7429923B2 (en) * 2004-10-22 2008-09-30 Honeywell International Inc. Neuronal sensor networks
WO2008092291A1 (en) 2007-01-17 2008-08-07 Honeywell International Inc. Microarray reader based on evanescent wave detection and method of reading a microarray
CA2709217C (en) 2007-12-19 2021-01-05 Singulex, Inc. Scanning analyzer for single molecule detection and methods of use
US8163561B2 (en) 2009-11-30 2012-04-24 Corning Incorporated Method for depth resolved sensing of biological entities based on surface plasmon resonance sensors
US8243276B2 (en) 2009-11-30 2012-08-14 Corning Incorporated Variable penetration depth biosensor
WO2011143791A1 (en) 2010-05-20 2011-11-24 Honeywell International Inc. Microarray reader based on evanescent wave detection
US9757330B2 (en) 2013-10-18 2017-09-12 Industrial Technology Research Institute Recipe for in-situ gel, and implant, drug delivery system formed thereby

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU557816B2 (en) * 1981-09-18 1987-01-08 Prutec Ltd. Method for the determination of species in solution with an optical wave-guide
IL70765A (en) * 1983-01-27 1988-07-31 Enzo Biochem Inc Substrates containing non-radioactive chemically-labeled polynucleotides and methods using them
US4558014A (en) * 1983-06-13 1985-12-10 Myron J. Block Assay apparatus and methods
US4737454A (en) * 1983-07-14 1988-04-12 Molecular Diagnostics, Inc. Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays
CA1266998A (en) * 1984-09-21 1990-03-27 Donald Bruce Keck Dielectric waveguide sensors and their use in immunoassays
DE3481644D1 (de) * 1984-12-10 1990-04-19 Prutec Ltd Verfahren zum optischen nachweis von parametern von substanzen in einem fluessigen analyt.

Also Published As

Publication number Publication date
AU7583887A (en) 1987-12-01
DK688D0 (da) 1988-01-04
DK688A (da) 1988-02-17
EP0245206A1 (en) 1987-11-11
FI875770A (fi) 1987-12-30
WO1987006956A1 (en) 1987-11-19
JPH01500221A (ja) 1989-01-26

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Owner name: INTRACEL CORPORATION