FI834023A0 - Tiofen-2-karboxylsyraderivat och foerfarande foer framstaellning av dem - Google Patents

Tiofen-2-karboxylsyraderivat och foerfarande foer framstaellning av dem

Info

Publication number
FI834023A0
FI834023A0 FI834023A FI834023A FI834023A0 FI 834023 A0 FI834023 A0 FI 834023A0 FI 834023 A FI834023 A FI 834023A FI 834023 A FI834023 A FI 834023A FI 834023 A0 FI834023 A0 FI 834023A0
Authority
FI
Finland
Prior art keywords
syraderated
framstaellning
foerfarande
dem
thiophene
Prior art date
Application number
FI834023A
Other languages
English (en)
Other versions
FI75565B (fi
FI75565C (fi
FI834023A (fi
Inventor
Dieter Binder
Christian Noe
Original Assignee
Laevosan Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laevosan Gmbh & Co Kg filed Critical Laevosan Gmbh & Co Kg
Publication of FI834023A0 publication Critical patent/FI834023A0/fi
Publication of FI834023A publication Critical patent/FI834023A/fi
Publication of FI75565B publication Critical patent/FI75565B/fi
Application granted granted Critical
Publication of FI75565C publication Critical patent/FI75565C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28Halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
FI834023A 1982-11-05 1983-11-02 Foerfarande foer framstaellning av terapeutiskt vaerdefulla tiofen-2-karboxylsyraderivat. FI75565C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0404182A AT376436B (de) 1982-11-05 1982-11-05 Verfahren zur herstellung neuer thiophen-2carbons[urederivate und pharmazeutisch vertraeglicher saeure- oder basenadditionssalze davon
AT404182 1982-11-05

Publications (4)

Publication Number Publication Date
FI834023A0 true FI834023A0 (fi) 1983-11-02
FI834023A FI834023A (fi) 1984-05-06
FI75565B FI75565B (fi) 1988-03-31
FI75565C FI75565C (fi) 1988-07-11

Family

ID=3558851

Family Applications (1)

Application Number Title Priority Date Filing Date
FI834023A FI75565C (fi) 1982-11-05 1983-11-02 Foerfarande foer framstaellning av terapeutiskt vaerdefulla tiofen-2-karboxylsyraderivat.

Country Status (9)

Country Link
US (1) US4590203A (fi)
EP (1) EP0109381B1 (fi)
JP (1) JPS59108780A (fi)
AT (1) AT376436B (fi)
CA (1) CA1209576A (fi)
DE (1) DE3364995D1 (fi)
DK (1) DK162645C (fi)
FI (1) FI75565C (fi)
PT (1) PT77613B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0284892B1 (de) * 1987-04-03 1990-10-31 Cl Pharma Aktiengesellschaft Neue 2-Thienyloxyessigsäurederivate, ein Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
AT395425B (de) * 1991-04-04 1992-12-28 Laevosan Gmbh & Co Kg Neue thiophen-2-carbonsaeurederivate und verfahren zu deren herstellung
US5608082A (en) * 1994-07-28 1997-03-04 Agouron Pharmaceuticals, Inc. Compounds useful as antiproliferative agents and GARFT inhibitors
US5527920A (en) * 1994-11-18 1996-06-18 Singh; Inder P. Economical manufacturing process for 1,2,3-triazoles
US6545163B1 (en) * 1995-10-02 2003-04-08 Napp Technologies Process to prepare 1-aryl-2-(1-imidazolyl) alkyl ethers and thioethers
JP5578809B2 (ja) * 2008-06-26 2014-08-27 石原産業株式会社 3−メチル−2−チオフェンカルボン酸の製造方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3186990A (en) * 1961-08-22 1965-06-01 Union Carbide Corp 2-thienylmethylmercaptoamidine hydrochlorides and cyclic derivatives thereof
SE339235B (fi) * 1965-06-01 1971-10-04 Haessle Ab
SU557755A3 (ru) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Способ получени производных имидазола
US3658813A (en) * 1970-01-13 1972-04-25 Janssen Pharmaceutica Nv 1-(beta-aryl-beta-(r-oxy)-ethyl)-imidazoles
JPS5734275B2 (fi) * 1973-07-30 1982-07-22
US4087536A (en) * 1976-05-04 1978-05-02 The Dow Chemical Company Method for the use of thienylvinylimidazoles as anthelmintics
DK151884C (da) * 1979-03-07 1988-06-13 Pfizer Analogifremgangsmaade til fremstilling af 3-(1-imidazolylalkyl)indolderivater eller farmaceutisk acceptable syreadditionssalte deraf
DE2950064A1 (de) * 1979-12-13 1981-06-19 Basf Ag, 6700 Ludwigshafen Piperidinderivate von 3-hydroxythiophen-2-carbonsaeure und -estern, ihre herstellung und diese enthaltende pharmazeutische zubereitungen
DE2951601A1 (de) * 1979-12-21 1981-07-02 C.H. Boehringer Sohn, 6507 Ingelheim Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben

Also Published As

Publication number Publication date
PT77613B (de) 1986-03-19
DK162645C (da) 1992-04-13
DE3364995D1 (en) 1986-09-04
PT77613A (de) 1983-12-01
US4590203A (en) 1986-05-20
EP0109381B1 (de) 1986-07-30
DK162645B (da) 1991-11-25
JPS59108780A (ja) 1984-06-23
FI75565B (fi) 1988-03-31
EP0109381A1 (de) 1984-05-23
AT376436B (de) 1984-11-26
FI75565C (fi) 1988-07-11
DK505583A (da) 1984-05-06
ATA404182A (de) 1984-04-15
CA1209576A (en) 1986-08-12
DK505583D0 (da) 1983-11-04
FI834023A (fi) 1984-05-06
JPH0210157B2 (fi) 1990-03-06

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Owner name: LAEVOSAN GESELLSCHAFT M.B.H.