FI70228C - Foerfarande foer framstaellning av en enkefalin-analog-peptid - Google Patents

Foerfarande foer framstaellning av en enkefalin-analog-peptid Download PDF

Info

Publication number
FI70228C
FI70228C FI770254A FI770254A FI70228C FI 70228 C FI70228 C FI 70228C FI 770254 A FI770254 A FI 770254A FI 770254 A FI770254 A FI 770254A FI 70228 C FI70228 C FI 70228C
Authority
FI
Finland
Prior art keywords
tyr
formula
peptide
ala
gly
Prior art date
Application number
FI770254A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI770254A7 (enrdf_load_stackoverflow
FI70228B (fi
Inventor
Samuel Wilkinson
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB2900/76A external-priority patent/GB1577114A/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI770254A7 publication Critical patent/FI770254A7/fi
Application granted granted Critical
Publication of FI70228B publication Critical patent/FI70228B/fi
Publication of FI70228C publication Critical patent/FI70228C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FI770254A 1976-01-26 1977-01-26 Foerfarande foer framstaellning av en enkefalin-analog-peptid FI70228C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB2900/76A GB1577114A (en) 1976-01-26 1976-01-26 Biologically active peptides
GB290076 1976-01-26
GB848176 1976-03-03
GB848176 1976-03-03
GB4882176 1976-11-23
GB4882176 1976-11-23

Publications (3)

Publication Number Publication Date
FI770254A7 FI770254A7 (enrdf_load_stackoverflow) 1977-07-27
FI70228B FI70228B (fi) 1986-02-28
FI70228C true FI70228C (fi) 1986-09-15

Family

ID=27254145

Family Applications (1)

Application Number Title Priority Date Filing Date
FI770254A FI70228C (fi) 1976-01-26 1977-01-26 Foerfarande foer framstaellning av en enkefalin-analog-peptid

Country Status (11)

Country Link
JP (1) JPS5291839A (enrdf_load_stackoverflow)
CH (1) CH644352A5 (enrdf_load_stackoverflow)
DE (1) DE2703109A1 (enrdf_load_stackoverflow)
DK (1) DK33177A (enrdf_load_stackoverflow)
ES (1) ES455365A1 (enrdf_load_stackoverflow)
FI (1) FI70228C (enrdf_load_stackoverflow)
FR (1) FR2338925A1 (enrdf_load_stackoverflow)
HU (1) HU184704B (enrdf_load_stackoverflow)
IL (1) IL51332A (enrdf_load_stackoverflow)
NL (1) NL7700785A (enrdf_load_stackoverflow)
SE (1) SE7708404L (enrdf_load_stackoverflow)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003000A (en) * 1975-05-27 1977-01-11 Sperry Rand Corporation Sinusoidal oscillator with electronically variable frequency
US4261888A (en) * 1976-04-12 1981-04-14 Sandoz Ltd. Organic compounds
FR2359817A1 (fr) * 1976-07-27 1978-02-24 Reckitt & Colmann Prod Ltd Nouveaux peptides, leur procede de preparation et composition therapeutique les contenant
GB1532148A (en) * 1976-08-09 1978-11-15 Searle & Co 1-substituted enkepholin derivatives
HU178001B (en) * 1976-09-16 1982-02-28 Gyogyszekutato Intezet Process for preparing new pentapeptides with morphine-like activity and derivatives thereof
DE2819277A1 (de) * 1977-05-16 1978-11-23 Sandoz Ag Neue polypeptidderivate, ihre herstellung und verwendung
GB2000784B (en) * 1977-07-05 1982-01-20 American Home Prod Analgesic polypetide
DE2862327D1 (en) * 1977-07-22 1983-11-10 Wellcome Found Pentapeptide-n-alkylamides and their acid addition salts, methods for preparation of these compounds and pharmaceutical formulations containing them
US4264491A (en) * 1977-10-03 1981-04-28 Eli Lilly And Company Analgesic compounds
HU182051B (en) * 1978-05-02 1983-12-28 Takeda Chemical Industries Ltd Process for preparing tetrapeptide-hydrazyde derivatives
US4278596A (en) * 1978-08-08 1981-07-14 American Home Products Corporation Analgesic pentapeptides
CA1175810A (en) * 1979-03-30 1984-10-09 Frank A. Momany Synthetic peptides having pituitary growth hormone releasing activity
US4247543A (en) * 1979-04-09 1981-01-27 Sandoz Ltd. Organic compounds
US4396606A (en) * 1979-11-05 1983-08-02 Addiction Research Foundation Novel polypeptide analgesics
DE3163199D1 (en) * 1980-07-17 1984-05-24 Sandoz Ag Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use
FR2488253A1 (fr) * 1980-08-08 1982-02-12 Roques Bernard Nouveaux peptides et leur application en therapeutique
BR8208035A (pt) * 1981-12-28 1983-11-22 Beckman Instruments Inc Peptideos sinteticos tendo atividade liberadora de hormonio do crescimento da pituitaria
US4491541A (en) * 1982-11-10 1985-01-01 Farmitalia Carlo Erba Peptides
JPH0680079B2 (ja) * 1984-11-09 1994-10-12 エーザイ株式会社 ポリペプチド
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
NZ258345A (en) * 1992-11-12 1996-03-26 Biomeasure Inc Peptides (opioid) capable of selectively binding to cell receptors
WO2010120691A2 (en) * 2009-04-13 2010-10-21 Elc Management Llc Methionine sulfoxide peptide, compositions and methods of use
TW201920234A (zh) 2017-09-11 2019-06-01 美商領導醫療有限公司 類鴉片促效劑肽及其用途

Also Published As

Publication number Publication date
CH644352A5 (en) 1984-07-31
NL7700785A (nl) 1977-07-28
SE7708404L (sv) 1977-07-27
IL51332A0 (en) 1977-03-31
JPS5291839A (en) 1977-08-02
ES455365A1 (es) 1978-05-16
FI770254A7 (enrdf_load_stackoverflow) 1977-07-27
HU184704B (en) 1984-10-29
FR2338925A1 (fr) 1977-08-19
FR2338925B1 (enrdf_load_stackoverflow) 1980-08-08
DE2703109A1 (de) 1977-08-04
IL51332A (en) 1980-09-16
DK33177A (da) 1977-07-27
FI70228B (fi) 1986-02-28

Similar Documents

Publication Publication Date Title
FI70228C (fi) Foerfarande foer framstaellning av en enkefalin-analog-peptid
US5723575A (en) Process for the preparation of backbone cyclic peptides
US4472305A (en) Hexapeptide amides
US4337247A (en) Tetrapeptidesemicarbazide derivatives and their production and use
Salvadori et al. Synthesis and pharmacological activity of dermorphin and its N‐terminal sequences
DE3044793A1 (de) N-adamentansubstituierte tetrapeptidamide und deren pharmakologisch vertraegliche salze
US4540682A (en) Pharmaceutical peptides, preparation, use and intermediates
US4839465A (en) Di-(D-tryptophyl and/or tetrahydropyridoindolylcarbonyl)-containing peptide amides and process for preparation thereof
US4264491A (en) Analgesic compounds
US4254106A (en) Biologically active amides
US4322340A (en) Pharmacologically active peptides
US4407746A (en) Cyclohexyl and phenyl substituted enkephalins
EP2669276A1 (en) Ornithine- and lysine-derivatives for the treatment of pain
DD200799A5 (de) Verfahren zur herstellung von peptiden
US4092304A (en) 4-Substituted enkephalin derivatives
US4322342A (en) Analgesic compounds
GB2146026A (en) Peptides and process for preparing the same
HU186375B (en) Process for the preparation of biologically active encephalina derivatives
Hardy et al. Peripherally acting enkephalin analogs. 1. Polar pentapeptides
US4468383A (en) Dimeric enkephalins
HU190915B (en) Process for preparing new tripeptide derivatives
HU185230B (en) Process for producing pharmacologically active encephaline analogous peptides
US4148785A (en) Analgesic polypeptide
FI75175B (fi) Process foer framstaellning av n-karboxialkylprolin innehaollande tripeptider.
US4204991A (en) Sarcosine1 dehydroalanine8 angiotensin II derivatives

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: THE WELLCOME FOUNDATION LIMITED