FI120311B - Menetelmiä solunsisäisiä sitoutumisproteiineja (PIL) koodaavien nukleiinihappojen ja niitä sisältävien virusten, vektoreiden ja farmaseuttisten koostumusten valmistamiseksi - Google Patents

Menetelmiä solunsisäisiä sitoutumisproteiineja (PIL) koodaavien nukleiinihappojen ja niitä sisältävien virusten, vektoreiden ja farmaseuttisten koostumusten valmistamiseksi Download PDF

Info

Publication number
FI120311B
FI120311B FI956057A FI956057A FI120311B FI 120311 B FI120311 B FI 120311B FI 956057 A FI956057 A FI 956057A FI 956057 A FI956057 A FI 956057A FI 120311 B FI120311 B FI 120311B
Authority
FI
Finland
Prior art keywords
nucleic acid
acid sequence
peptide
antibody
virus
Prior art date
Application number
FI956057A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI956057A0 (fi
FI956057A (fi
Inventor
Bruno Tocque
Fabien Schweighoffer
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of FI956057A0 publication Critical patent/FI956057A0/fi
Publication of FI956057A publication Critical patent/FI956057A/fi
Application granted granted Critical
Publication of FI120311B publication Critical patent/FI120311B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/084Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1072Regulatory proteins, e.g. tat, rev, vpt
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI956057A 1993-06-16 1995-12-15 Menetelmiä solunsisäisiä sitoutumisproteiineja (PIL) koodaavien nukleiinihappojen ja niitä sisältävien virusten, vektoreiden ja farmaseuttisten koostumusten valmistamiseksi FI120311B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9307241A FR2706486B1 (fr) 1993-06-16 1993-06-16 Séquences nucléiques, vecteurs les contenant, compositions pharmaceutiques et utilisations thérapeutiques.
FR9307241 1993-06-16
FR9400714 1994-06-15
PCT/FR1994/000714 WO1994029446A2 (fr) 1993-06-16 1994-06-15 Proteines intracellulaires de liaison (pil) et leurs utilisations

Publications (3)

Publication Number Publication Date
FI956057A0 FI956057A0 (fi) 1995-12-15
FI956057A FI956057A (fi) 1995-12-15
FI120311B true FI120311B (fi) 2009-09-15

Family

ID=9448183

Family Applications (1)

Application Number Title Priority Date Filing Date
FI956057A FI120311B (fi) 1993-06-16 1995-12-15 Menetelmiä solunsisäisiä sitoutumisproteiineja (PIL) koodaavien nukleiinihappojen ja niitä sisältävien virusten, vektoreiden ja farmaseuttisten koostumusten valmistamiseksi

Country Status (24)

Country Link
US (1) US6159947A (ru)
EP (1) EP0703980B1 (ru)
JP (1) JP4384260B2 (ru)
KR (1) KR100342233B1 (ru)
CN (1) CN1076052C (ru)
AT (1) ATE231916T1 (ru)
AU (1) AU7076394A (ru)
BR (1) BR9407512A (ru)
CA (1) CA2165458C (ru)
CZ (1) CZ289039B6 (ru)
DE (1) DE69432075T2 (ru)
DK (1) DK0703980T3 (ru)
ES (1) ES2191031T3 (ru)
FI (1) FI120311B (ru)
FR (1) FR2706486B1 (ru)
HU (1) HU219138B (ru)
NO (1) NO319466B1 (ru)
NZ (1) NZ268038A (ru)
PL (1) PL180760B1 (ru)
RU (1) RU2218400C2 (ru)
SK (1) SK285169B6 (ru)
UA (1) UA46709C2 (ru)
WO (1) WO1994029446A2 (ru)
ZA (1) ZA944303B (ru)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8003342B1 (en) 1990-04-18 2011-08-23 Board Of Regents, The University Of Texas System Method for identifying farnesyl transferase inhibitors
US6790633B1 (en) * 1990-04-18 2004-09-14 Michael S. Brown Method of inhibiting a farnesyl transferase enzyme
FR2724320B1 (fr) * 1994-09-13 1996-12-20 Transgene Sa Nouvel implant pour le traitement des maladies acquises
US5518042A (en) * 1994-09-16 1996-05-21 Huyck Licensco, Inc. Papermaker's forming fabric with additional cross machine direction locator and fiber supporting yarns
FR2738151B1 (fr) * 1995-09-04 1997-09-26 Rhone Poulenc Rorer Sa Antagonistes de l'activite oncogenique de la proteine mdm2, et leur utilisation dans le traitement des cancers
US7008776B1 (en) 1996-12-06 2006-03-07 Aventis Pharmaceuticals Inc. Compositions and methods for effecting the levels of high density lipoprotein (HDL) cholesterol and apolipoprotein AI very low density lipoprotein (VLDL) cholesterol and low density lipoprotein (LDL) cholesterol
PL191624B1 (pl) * 1996-12-06 2006-06-30 Aventis Pharma Inc Wyizolowany polipeptyd kodowany przez gen białka podobnego do lipazy, jego fragment antygenowy, wyizolowany kwas nukleinowy kodujący ten polipeptyd i wektor go zawierający, zrekombinowana komórka zawierająca ten wektor, sposób wytwarzania polipeptydu, przeciwciało zdolne do wiązania polipeptydu i komórka hybrydomy je wytwarzająca, kompozycja farmaceutyczna, sposób wyszukiwania agonistów lub antagonistów aktywności polipeptydu, sposób enzymatycznej hydrolizy in vitro estru fosfatydylocholiny, zastosowanie polipeptydu oraz transgeniczna mysz
FR2758569B1 (fr) * 1997-01-20 1999-04-02 Centre Nat Rech Scient Materiel biologique pour le traitement d'un mammifere par transfert de gene d'anticorps et composition pharmaceutique le concernant
WO2000050089A2 (en) * 1999-02-26 2000-08-31 Mindset Biopharmaceuticals (Usa) Ltd. Regulation of the stability of recombinant proteins and antiboodies
FR2794771B1 (fr) 1999-06-11 2001-08-10 Aventis Pharma Sa Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis)
GB0018307D0 (en) 2000-07-26 2000-09-13 Aventis Pharm Prod Inc Polypeptides
AU4793101A (en) 2000-03-31 2001-10-15 Aventis Pharm Prod Inc Nuclear factor kb inducing factor
AU2002338446A1 (en) * 2001-01-23 2002-11-05 University Of Rochester Medical Center Methods of producing or identifying intrabodies in eukaryotic cells
WO2012162628A2 (en) 2011-05-25 2012-11-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Lipopeptide inhibitors of ras oncoproteins
KR101602870B1 (ko) 2014-07-22 2016-03-21 아주대학교산학협력단 완전한 이뮤노글로불린 형태의 항체를 세포막을 투과하여 세포질에 위치시키는 방법 및 그의 이용
KR101602876B1 (ko) 2014-07-22 2016-03-11 아주대학교산학협력단 완전한 이뮤노글로불린 형태의 세포질 침투능을 갖는 항체를 이용하여 세포내 활성화된 ras를 억제하는 방법 및 그의 이용
BR122020006914B8 (pt) * 2014-10-23 2023-01-31 Singh Biotechnology Llc Anticorpo de domínio único anti-tnf-alfa e seu uso, métodos in vitro para medir os níveis do referido anticorpo e para diagnosticar um distúrbio mediado por um componente intracelular, polipeptídeo isolado e composição compreendendo o referido anticorpo ou polipeptídeo isolado
US20180072815A1 (en) 2014-10-23 2018-03-15 Singh Biotechnology, Llc Single Domain Antibodies Directed Against Intracellular Antigens
TWI746473B (zh) 2015-11-02 2021-11-21 美商辛分子醫藥有限公司 針對細胞內抗原之單域抗體
AU2017271189B2 (en) 2016-05-27 2020-02-20 Orum Therapeutics Inc. Cytosol-penetrating antibody and use thereof
WO2019244086A1 (en) 2018-06-21 2019-12-26 Orum Therapeutics Inc. Cell/tissue-specific cell-penetrating antibodies
CN110981943B (zh) * 2019-12-02 2021-08-03 清华大学 多肽及其在制备药物中的用途和药物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
DE3915952A1 (de) * 1989-05-12 1990-12-06 Peter Werner Wirkstoff/medikament/biotechnologisches verfahren zur behandlung von erkrankungen, die mit exo- oder endogenen intrazellulaeren proteinen (onkogene etc.) assoziert sind
EP0556197A4 (en) * 1990-09-25 1994-05-18 Univ Connecticut Prolonging expression of polynucleotides introduced into a cell
CA2072249C (en) * 1991-06-28 2003-06-17 Saiko Hosokawa Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
AU675413B2 (en) * 1991-09-30 1997-02-06 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Recombinant immunotoxins
AU668374B2 (en) * 1991-12-10 1996-05-02 Dana-Farber Cancer Institute Reactive neutralizing human anti-GP120 recombinant antibody, DNA coding the same and use thereof
DE69334095T2 (de) * 1992-07-17 2007-04-12 Dana-Farber Cancer Institute, Boston Verfahren zur intrazellulären Bindung von zielgerichteten Molekülen

Also Published As

Publication number Publication date
CA2165458A1 (fr) 1994-12-22
PL312213A1 (en) 1996-04-01
FR2706486B1 (fr) 1995-09-01
JP4384260B2 (ja) 2009-12-16
HU219138B (hu) 2001-02-28
WO1994029446A3 (fr) 1995-02-02
DE69432075T2 (de) 2003-09-04
ES2191031T3 (es) 2003-09-01
DE69432075D1 (de) 2003-03-06
JPH08511162A (ja) 1996-11-26
FR2706486A1 (fr) 1994-12-23
UA46709C2 (uk) 2002-06-17
CZ289039B6 (cs) 2001-10-17
CA2165458C (fr) 2011-05-10
NO955011L (no) 1995-12-11
AU7076394A (en) 1995-01-03
EP0703980A1 (fr) 1996-04-03
SK285169B6 (sk) 2006-07-07
US6159947A (en) 2000-12-12
CZ329595A3 (en) 1996-03-13
NO955011D0 (no) 1995-12-11
SK156895A3 (en) 1996-05-08
EP0703980B1 (fr) 2003-01-29
FI956057A0 (fi) 1995-12-15
ATE231916T1 (de) 2003-02-15
HUT74266A (en) 1996-11-28
NO319466B1 (no) 2005-08-15
WO1994029446A2 (fr) 1994-12-22
RU2218400C2 (ru) 2003-12-10
KR100342233B1 (ko) 2002-12-05
NZ268038A (en) 1997-12-19
HU9503615D0 (en) 1996-02-28
DK0703980T3 (da) 2003-05-19
ZA944303B (en) 1995-02-14
BR9407512A (pt) 1997-01-07
PL180760B1 (pl) 2001-04-30
CN1076052C (zh) 2001-12-12
FI956057A (fi) 1995-12-15
CN1126491A (zh) 1996-07-10

Similar Documents

Publication Publication Date Title
FI120311B (fi) Menetelmiä solunsisäisiä sitoutumisproteiineja (PIL) koodaavien nukleiinihappojen ja niitä sisältävien virusten, vektoreiden ja farmaseuttisten koostumusten valmistamiseksi
JP7374995B2 (ja) 抗pd-1/抗vegfa二官能性抗体、その医薬組成物およびその使用
US7186697B2 (en) Nucleic acid delivery system, methods of synthesis and use thereof
KR102017396B1 (ko) 항-ctla4 모노클로날 항체 또는 그의 항원 결합 단편, 제약 조성물 및 용도
KR101944263B1 (ko) 에이치비브이 감염 및 관련 질병의 치료를 위한 폴리펩타이드 및 항체
KR100337069B1 (ko) 항-hiv모노클로날항체
JP2006523086A (ja) 発癌性形態のrasに対する細胞内発現抗体
JP2024514246A (ja) Cldn18.2抗原結合タンパク質およびその使用
WO1997021809A1 (en) Dna sequence encoding the tumor suppressor ing1
Giovane et al. Targetting of the N‐terminal domain of the human papillomavirus type 16 E6 oncoprotein with monomeric scFvs blocks the E6‐mediated degradation of cellular p53
JP4371178B2 (ja) 抗p53一本鎖抗体フラグメント及びその使用
EP1002864A1 (en) HIgR and related V domain for the manufacture of a medicament for preventing or treating HSV-1, HSV-2 and BHV infections
EP0846761A1 (en) A novel transcription factor expressed in cycling cells, nucleic acid molecules encoding said transcription factor and its promoter region and uses thereof
AU722702B2 (en) Intracellular binding proteins and use thereof
US5439886A (en) Monoclonal antibody, polypeptides and production thereof
ITMI950676A1 (it) Vaccini polinucleotidici
CN111978393A (zh) 抗乙肝病毒新型抗体及其用途
KR20240128132A (ko) 중화 항-tl1a 단일 클론 항체
Curiel Intracellular Antibody-Mediated Knockout of the ErbB-2 Oncoprotein as a Cancer Gene Therapy Approach

Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: AVENTIS PHARMA S.A.

FG Patent granted

Ref document number: 120311

Country of ref document: FI

MM Patent lapsed