FI107434B - Osmoottiset pumput - Google Patents
Osmoottiset pumput Download PDFInfo
- Publication number
- FI107434B FI107434B FI915904A FI915904A FI107434B FI 107434 B FI107434 B FI 107434B FI 915904 A FI915904 A FI 915904A FI 915904 A FI915904 A FI 915904A FI 107434 B FI107434 B FI 107434B
- Authority
- FI
- Finland
- Prior art keywords
- osmotic
- chamber
- piston
- fluid
- pump according
- Prior art date
Links
- 230000003204 osmotic effect Effects 0.000 claims description 167
- 239000012530 fluid Substances 0.000 claims description 121
- 150000003839 salts Chemical class 0.000 claims description 50
- 239000012528 membrane Substances 0.000 claims description 48
- 238000003860 storage Methods 0.000 claims description 32
- 230000004888 barrier function Effects 0.000 claims description 30
- 239000000126 substance Substances 0.000 claims description 23
- 238000004891 communication Methods 0.000 claims description 3
- 235000002639 sodium chloride Nutrition 0.000 description 46
- 239000003795 chemical substances by application Substances 0.000 description 18
- 239000007924 injection Substances 0.000 description 11
- 238000002347 injection Methods 0.000 description 11
- 239000007788 liquid Substances 0.000 description 11
- 239000003981 vehicle Substances 0.000 description 10
- 239000003814 drug Substances 0.000 description 7
- 239000000463 material Substances 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 230000004913 activation Effects 0.000 description 5
- 230000009977 dual effect Effects 0.000 description 5
- 238000001802 infusion Methods 0.000 description 5
- 239000004033 plastic Substances 0.000 description 5
- 229920003023 plastic Polymers 0.000 description 5
- 230000009172 bursting Effects 0.000 description 4
- 230000002779 inactivation Effects 0.000 description 4
- 230000007246 mechanism Effects 0.000 description 4
- 241000220317 Rosa Species 0.000 description 3
- 230000003213 activating effect Effects 0.000 description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 3
- 229910052782 aluminium Inorganic materials 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 230000000994 depressogenic effect Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 238000007911 parenteral administration Methods 0.000 description 3
- 239000008177 pharmaceutical agent Substances 0.000 description 3
- 238000003825 pressing Methods 0.000 description 3
- 108090000765 processed proteins & peptides Proteins 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000000881 depressing effect Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000010408 film Substances 0.000 description 2
- 239000011888 foil Substances 0.000 description 2
- 238000001990 intravenous administration Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000005192 partition Methods 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000729 antidote Substances 0.000 description 1
- 229940075522 antidotes Drugs 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 229920005549 butyl rubber Polymers 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 229920006217 cellulose acetate butyrate Polymers 0.000 description 1
- 229920001727 cellulose butyrate Polymers 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 229940124447 delivery agent Drugs 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229920001179 medium density polyethylene Polymers 0.000 description 1
- 239000004701 medium-density polyethylene Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000003094 microcapsule Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920001195 polyisoprene Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000009291 secondary effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229920003048 styrene butadiene rubber Polymers 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M2005/14513—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Details Of Reciprocating Pumps (AREA)
- Reciprocating Pumps (AREA)
- Medicinal Preparation (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909027422A GB9027422D0 (en) | 1990-12-18 | 1990-12-18 | Osmotically driven infusion device |
| GB9027422 | 1990-12-18 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI915904A0 FI915904A0 (fi) | 1991-12-16 |
| FI915904A7 FI915904A7 (fi) | 1992-06-19 |
| FI107434B true FI107434B (fi) | 2001-08-15 |
Family
ID=10687181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI915904A FI107434B (fi) | 1990-12-18 | 1991-12-16 | Osmoottiset pumput |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US5279608A (cs) |
| JP (1) | JP3058738B2 (cs) |
| KR (1) | KR920011529A (cs) |
| AR (1) | AR244091A1 (cs) |
| AT (1) | AT403884B (cs) |
| AU (1) | AU652199B2 (cs) |
| BE (1) | BE1004788A4 (cs) |
| CA (1) | CA2057817A1 (cs) |
| CH (1) | CH686871A5 (cs) |
| CZ (1) | CZ282437B6 (cs) |
| DE (1) | DE4141819B4 (cs) |
| DK (1) | DK174860B1 (cs) |
| DZ (1) | DZ1548A1 (cs) |
| ES (1) | ES2055649B1 (cs) |
| FI (1) | FI107434B (cs) |
| FR (1) | FR2670387B1 (cs) |
| GB (1) | GB9027422D0 (cs) |
| GR (1) | GR1001122B (cs) |
| HK (1) | HK111895A (cs) |
| IE (1) | IE67181B1 (cs) |
| IT (1) | IT1252243B (cs) |
| LU (1) | LU88040A1 (cs) |
| MA (1) | MA22368A1 (cs) |
| MY (1) | MY131056A (cs) |
| NL (1) | NL194432C (cs) |
| NO (1) | NO302686B1 (cs) |
| NZ (1) | NZ240824A (cs) |
| OA (1) | OA09413A (cs) |
| PT (1) | PT99828B (cs) |
| RU (1) | RU2098141C1 (cs) |
| SE (1) | SE503662C2 (cs) |
| TN (1) | TNSN91121A1 (cs) |
| ZA (1) | ZA919342B (cs) |
Families Citing this family (125)
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| US5595760A (en) * | 1994-09-02 | 1997-01-21 | Delab | Sustained release of peptides from pharmaceutical compositions |
| US6132420A (en) * | 1996-02-02 | 2000-10-17 | Alza Corporation | Osmotic delivery system and method for enhancing start-up and performance of osmotic delivery systems |
| US6395292B2 (en) * | 1996-02-02 | 2002-05-28 | Alza Corporation | Sustained delivery of an active agent using an implantable system |
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| CA2591581C (en) * | 1996-12-20 | 2013-01-29 | Alza Corporation | Gel composition and methods |
| US6994851B1 (en) * | 1997-07-10 | 2006-02-07 | Mannkind Corporation | Method of inducing a CTL response |
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| US6610042B2 (en) | 1997-12-05 | 2003-08-26 | Felton Medical, Inc. | Disposable unit-dose jet-injection syringe for pre-filled and/or transfilled liquid injectable medical drug or vaccine products and method thereof |
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1991
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- 1991-11-26 ZA ZA919342A patent/ZA919342B/xx unknown
- 1991-11-27 GR GR910100481A patent/GR1001122B/el not_active IP Right Cessation
- 1991-11-29 AR AR91321277A patent/AR244091A1/es active
- 1991-12-02 NZ NZ240824A patent/NZ240824A/en unknown
- 1991-12-03 CH CH03552/91A patent/CH686871A5/fr not_active IP Right Cessation
- 1991-12-04 US US07/802,326 patent/US5279608A/en not_active Expired - Fee Related
- 1991-12-10 BE BE9101123A patent/BE1004788A4/fr not_active IP Right Cessation
- 1991-12-10 IT ITMI913307A patent/IT1252243B/it active IP Right Grant
- 1991-12-11 MY MYPI91002293A patent/MY131056A/en unknown
- 1991-12-12 LU LU88040A patent/LU88040A1/fr unknown
- 1991-12-16 AT AT0248891A patent/AT403884B/de not_active IP Right Cessation
- 1991-12-16 FI FI915904A patent/FI107434B/fi not_active IP Right Cessation
- 1991-12-16 SE SE9103717A patent/SE503662C2/sv not_active IP Right Cessation
- 1991-12-16 MA MA22652A patent/MA22368A1/fr unknown
- 1991-12-17 DK DK199102019A patent/DK174860B1/da not_active IP Right Cessation
- 1991-12-17 DZ DZ910168A patent/DZ1548A1/fr active
- 1991-12-17 IE IE438591A patent/IE67181B1/en not_active IP Right Cessation
- 1991-12-17 ES ES09102800A patent/ES2055649B1/es not_active Expired - Fee Related
- 1991-12-17 KR KR1019910023193A patent/KR920011529A/ko not_active Ceased
- 1991-12-17 RU SU915010426A patent/RU2098141C1/ru not_active IP Right Cessation
- 1991-12-17 PT PT99828A patent/PT99828B/pt not_active IP Right Cessation
- 1991-12-17 NO NO914990A patent/NO302686B1/no unknown
- 1991-12-17 CA CA002057817A patent/CA2057817A1/en not_active Abandoned
- 1991-12-17 AU AU89727/91A patent/AU652199B2/en not_active Ceased
- 1991-12-18 DE DE4141819A patent/DE4141819B4/de not_active Expired - Fee Related
- 1991-12-18 FR FR9115698A patent/FR2670387B1/fr not_active Expired - Fee Related
- 1991-12-18 TN TNTNSN91121A patent/TNSN91121A1/fr unknown
- 1991-12-18 JP JP3334996A patent/JP3058738B2/ja not_active Expired - Fee Related
- 1991-12-18 OA OA60116A patent/OA09413A/xx unknown
- 1991-12-18 CZ CS913877A patent/CZ282437B6/cs not_active IP Right Cessation
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1995
- 1995-07-06 HK HK111895A patent/HK111895A/xx not_active IP Right Cessation
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| Date | Code | Title | Description |
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| MA | Patent expired |