ES8205796A1 - Sales acidas de adicion, amorfas a los rayos x,aceptables fisiologicamente,de alcaloides de la ergotina y alcaloides de la dihidroergotina, proceso para la preparacion de ellas y su uso terapeutico - Google Patents

Sales acidas de adicion, amorfas a los rayos x,aceptables fisiologicamente,de alcaloides de la ergotina y alcaloides de la dihidroergotina, proceso para la preparacion de ellas y su uso terapeutico

Info

Publication number
ES8205796A1
ES8205796A1 ES496969A ES496969A ES8205796A1 ES 8205796 A1 ES8205796 A1 ES 8205796A1 ES 496969 A ES496969 A ES 496969A ES 496969 A ES496969 A ES 496969A ES 8205796 A1 ES8205796 A1 ES 8205796A1
Authority
ES
Spain
Prior art keywords
alkaloids
physiologically acceptable
acid addition
addition salts
dihydroergot
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES496969A
Other languages
English (en)
Other versions
ES496969A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lek Pharmaceuticals dd
Original Assignee
Lek Pharmaceuticals and Chemical Co dd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals and Chemical Co dd filed Critical Lek Pharmaceuticals and Chemical Co dd
Publication of ES496969A0 publication Critical patent/ES496969A0/es
Publication of ES8205796A1 publication Critical patent/ES8205796A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02—Ergot alkaloids of the cyclic peptide type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE SALES ACIDAS DE ADICION, AMORFAS A LOS RAYOS X, FISIOLOGICAMENTE ACEPTABLES. DE ALCALOIDES DE LA ERGOTINA Y DE LA DHIHIDROERGOTINA, DE FORMULA (I), EN LA QUE HA ES UN ACIDO ORGANICO MONOBASICO O DIBASICO; X-Y REPRESENTA EL GRUPO -CH2-CH= O EL GRUPO -CH=C=; R1 ES AQUILO C1-4, Y R2 ES ALQUILO C1-2 O BENCILO. CONSISTE EN LA DISOLUCION DEL ALCOLOIDE EN UN DISOLVENTE INERTE QUE CONTIENE DEL 1 A 1,05 MOLES DE UN ACIDO FISIOLOGICAMENTE COMPATIBLE POR MOL DE ALCAOLIDE, SEGUIDA DE LA PRECIPITACION DE LA SAL DE ADICION, EN FORMA AMORFA A LOS RAYOS X, POR ADICION DE UN DISOLVENTE PRECIPITANTE.
ES496969A 1979-11-22 1980-11-19 Sales acidas de adicion, amorfas a los rayos x,aceptables fisiologicamente,de alcaloides de la ergotina y alcaloides de la dihidroergotina, proceso para la preparacion de ellas y su uso terapeutico Expired ES8205796A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU2867/79A YU41681B (en) 1979-11-22 1979-11-22 Process for preparing x-ray amorhous physiologically tolerated acid additional salts of ergot alcaloids and dihydroergot alcaloids

Publications (2)

Publication Number Publication Date
ES496969A0 ES496969A0 (es) 1982-08-01
ES8205796A1 true ES8205796A1 (es) 1982-08-01

Family

ID=25558910

Family Applications (1)

Application Number Title Priority Date Filing Date
ES496969A Expired ES8205796A1 (es) 1979-11-22 1980-11-19 Sales acidas de adicion, amorfas a los rayos x,aceptables fisiologicamente,de alcaloides de la ergotina y alcaloides de la dihidroergotina, proceso para la preparacion de ellas y su uso terapeutico

Country Status (10)

Country Link
JP (1) JPS56164195A (es)
BE (1) BE886262A (es)
DE (1) DE3043832A1 (es)
ES (1) ES8205796A1 (es)
FR (1) FR2470133A1 (es)
GB (1) GB2063864B (es)
LU (1) LU82945A1 (es)
NL (1) NL8006341A (es)
PT (1) PT72078B (es)
YU (1) YU41681B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU87190A1 (fr) * 1988-04-06 1989-11-14 Wurth Paul Sa Machine de percage de trous de coulee d'un four a cuve

Also Published As

Publication number Publication date
GB2063864A (en) 1981-06-10
PT72078A (en) 1980-12-01
NL8006341A (nl) 1981-06-16
BE886262A (fr) 1981-03-16
JPS56164195A (en) 1981-12-17
PT72078B (en) 1981-09-29
GB2063864B (en) 1983-07-20
YU286779A (en) 1983-06-30
FR2470133B3 (es) 1982-09-03
LU82945A1 (de) 1981-03-26
YU41681B (en) 1987-12-31
ES496969A0 (es) 1982-08-01
FR2470133A1 (fr) 1981-05-29
DE3043832A1 (de) 1981-09-17

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