ES383868A1 - Un procedimiento de preparar oxindolcarboxamidas. - Google Patents
Un procedimiento de preparar oxindolcarboxamidas.Info
- Publication number
- ES383868A1 ES383868A1 ES383868A ES383868A ES383868A1 ES 383868 A1 ES383868 A1 ES 383868A1 ES 383868 A ES383868 A ES 383868A ES 383868 A ES383868 A ES 383868A ES 383868 A1 ES383868 A1 ES 383868A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- formula
- phenyl
- oxo
- dihydroindole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004455 (C1-C3) alkylthio group Chemical group 0.000 abstract 1
- RVPIGWJIDHZSBT-UHFFFAOYSA-N 2-oxo-N-phenyl-1,3-dihydroindole-3-carboxamide Chemical class O=C1NC2=CC=CC=C2C1C(=O)NC1=CC=CC=C1 RVPIGWJIDHZSBT-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 235000013877 carbamide Nutrition 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 di-substituted phenyl Chemical group 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- JYGFTBXVXVMTGB-UHFFFAOYSA-N indolin-2-one Chemical class C1=CC=C2NC(=O)CC2=C1 JYGFTBXVXVMTGB-UHFFFAOYSA-N 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- DGTNSSLYPYDJGL-UHFFFAOYSA-N phenyl isocyanate Chemical class O=C=NC1=CC=CC=C1 DGTNSSLYPYDJGL-UHFFFAOYSA-N 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
- 150000003672 ureas Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86673869A | 1969-10-15 | 1969-10-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES383868A1 true ES383868A1 (es) | 1973-08-16 |
Family
ID=25348298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES383868A Expired ES383868A1 (es) | 1969-10-15 | 1970-09-22 | Un procedimiento de preparar oxindolcarboxamidas. |
Country Status (11)
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3882236A (en) * | 1973-12-26 | 1975-05-06 | Lilly Co Eli | Pharmaceutical compositions containing substituted 2-oxo-indolines and the use thereof to treat anxiety and tension |
| JPS5235956U (enrdf_load_stackoverflow) * | 1975-09-05 | 1977-03-14 | ||
| IN163263B (enrdf_load_stackoverflow) * | 1984-02-07 | 1988-08-27 | Pfizer | |
| US4721712A (en) * | 1984-06-12 | 1988-01-26 | Pfizer Inc. | 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents |
| ATE41420T1 (de) * | 1984-02-07 | 1989-04-15 | Pfizer | 1,3-disubstituierte 2-oxindole und deren anwendung als analgetische und antiinflammatorische mittel. |
| US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
| US4569942A (en) * | 1984-05-04 | 1986-02-11 | Pfizer Inc. | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents |
| US4695571A (en) * | 1984-08-24 | 1987-09-22 | Pfizer Inc. | Tricyclic oxindole antiinflammatory agents |
| US4690943A (en) * | 1984-09-19 | 1987-09-01 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| US4686224A (en) * | 1984-10-31 | 1987-08-11 | Pfizer Inc. | Oxindole antiinflammatory agents |
| US4644005A (en) * | 1984-10-31 | 1987-02-17 | Pfizer Inc. | Oxindole antiinflammatory agents |
| US4678802A (en) * | 1985-07-09 | 1987-07-07 | Pfizer Inc. | 1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents |
| US4791131A (en) * | 1985-07-09 | 1988-12-13 | Pfizer Inc. | Analgesic and antiinflammatory 1-acyl-2-oxindole-3-carboxamides |
| US4730004A (en) * | 1986-01-22 | 1988-03-08 | Pfizer Inc. | Analgesic and anti-inflammatory 1-acyl-2-oxindole-3-carboxamides |
| US4791129A (en) * | 1987-01-20 | 1988-12-13 | Pfizer Inc. | 1,3-dicarboxamidooxindoles as analgesic and antiinflammatory agents |
| RO109195B1 (ro) * | 1988-10-18 | 1994-12-30 | Pfizer | Derivati de 3-acil-2-oxindol-1-carboxamide |
| US5047554A (en) * | 1989-04-18 | 1991-09-10 | Pfizer Inc. | 3-substituted-2-oxindole derivatives |
| US5300655A (en) * | 1989-04-18 | 1994-04-05 | Pfizer Inc. | 2-carboxy-thiophene derivatives |
| GB8915449D0 (en) * | 1989-07-06 | 1989-08-23 | Unicorn Ind Plc | Grinding tools |
| US5023265A (en) * | 1990-06-01 | 1991-06-11 | Schering Corporation | Substituted 1-H-pyrrolopyridine-3-carboxamides |
| US5449788A (en) * | 1994-01-28 | 1995-09-12 | Catalytica, Inc. | Process for preparing 2-oxindole-1-carboxamides |
| US6469181B1 (en) | 1995-01-30 | 2002-10-22 | Catalytica, Inc. | Process for preparing 2-oxindoles and N-hydroxy-2-oxindoles |
-
0
- BE BE756447D patent/BE756447A/xx unknown
-
1969
- 1969-10-15 US US866738A patent/US3634453A/en not_active Expired - Lifetime
- 1969-12-17 BR BR215247/69A patent/BR6915247D0/pt unknown
- 1969-12-19 GB GB62142/69A patent/GB1247113A/en not_active Expired
-
1970
- 1970-09-22 DE DE19702046595 patent/DE2046595A1/de active Pending
- 1970-09-22 ES ES383868A patent/ES383868A1/es not_active Expired
- 1970-09-22 JP JP45082604A patent/JPS4835263B1/ja active Pending
- 1970-09-23 FR FR7034441A patent/FR2070130B1/fr not_active Expired
- 1970-09-23 SE SE12949/70A patent/SE368007B/xx unknown
- 1970-10-15 CH CH1528370A patent/CH517094A/fr not_active IP Right Cessation
- 1970-10-15 NL NL7015130A patent/NL7015130A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2046595A1 (de) | 1971-04-22 |
| FR2070130B1 (enrdf_load_stackoverflow) | 1974-08-30 |
| FR2070130A1 (enrdf_load_stackoverflow) | 1971-09-10 |
| GB1247113A (en) | 1971-09-22 |
| SE368007B (enrdf_load_stackoverflow) | 1974-06-17 |
| BR6915247D0 (pt) | 1973-04-19 |
| NL7015130A (enrdf_load_stackoverflow) | 1971-04-19 |
| US3634453A (en) | 1972-01-11 |
| CH517094A (fr) | 1971-12-31 |
| BE756447A (fr) | 1971-03-22 |
| JPS4835263B1 (enrdf_load_stackoverflow) | 1973-10-26 |
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