ES2870505T3 - Gel de cartílago para la reparación cartilaginosa, que comprende quitosano y condrocitos - Google Patents
Gel de cartílago para la reparación cartilaginosa, que comprende quitosano y condrocitos Download PDFInfo
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- ES2870505T3 ES2870505T3 ES15817457T ES15817457T ES2870505T3 ES 2870505 T3 ES2870505 T3 ES 2870505T3 ES 15817457 T ES15817457 T ES 15817457T ES 15817457 T ES15817457 T ES 15817457T ES 2870505 T3 ES2870505 T3 ES 2870505T3
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
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- A—HUMAN NECESSITIES
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
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- A—HUMAN NECESSITIES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/56—Fibrin; Thrombin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Rheumatology (AREA)
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- Urology & Nephrology (AREA)
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- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
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- Vascular Medicine (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
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- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| FR1461746A FR3029116B1 (fr) | 2014-12-01 | 2014-12-01 | Procede d'obtention d'un gel de cartilage pour la reparation cartilagineuse, comprenant du chitosane et des chondrocytes |
| PCT/FR2015/053271 WO2016087762A1 (fr) | 2014-12-01 | 2015-12-01 | Gel de cartilage pour la réparation cartilagineuse, comprenant du chitosane et des chondrocytes |
Publications (1)
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| ES2870505T3 true ES2870505T3 (es) | 2021-10-27 |
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| ES15817457T Active ES2870505T3 (es) | 2014-12-01 | 2015-12-01 | Gel de cartílago para la reparación cartilaginosa, que comprende quitosano y condrocitos |
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| JP (1) | JP6821583B2 (https=) |
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| DK (1) | DK3226923T3 (https=) |
| ES (1) | ES2870505T3 (https=) |
| FR (2) | FR3029116B1 (https=) |
| PT (1) | PT3226923T (https=) |
| WO (1) | WO2016087762A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
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| FR3038318B1 (fr) * | 2015-07-02 | 2017-08-04 | Univ De Lille 1 Sciences Et Technologies | Procede de fabrication d'hydrogel a base de chitosan et de polyelectrolytes charges negativement et materiau poreux alveolaire issu dudit hydrogel |
| US10898608B2 (en) | 2017-02-02 | 2021-01-26 | Nanofiber Solutions, Llc | Methods of improving bone-soft tissue healing using electrospun fibers |
| EP3595515A4 (en) | 2017-03-14 | 2020-12-30 | University of Connecticut | BIODEGRADABLE PRESSURE SENSOR |
| FR3074043B1 (fr) | 2017-11-28 | 2020-11-13 | Kiomed Pharma | Chitosane a charge anionique |
| FR3074044B1 (fr) | 2017-11-28 | 2019-11-01 | Kiomed Pharma | Carboxyalkyl chitosane |
| WO2019113511A1 (en) * | 2017-12-08 | 2019-06-13 | Cohen Brian S | Electrospun fibers for the repair and regrowth of hyaline cartilage |
| CN108774330B (zh) * | 2018-08-30 | 2020-11-10 | 华熙生物科技股份有限公司 | 一种交联透明质酸凝胶的制备方法及所得产品和应用 |
| JP2022513442A (ja) | 2018-12-11 | 2022-02-08 | ナノファイバー ソリューションズ、エルエルシー | 電界紡糸繊維を使用した慢性創傷の治療方法 |
| US11826495B2 (en) | 2019-03-01 | 2023-11-28 | University Of Connecticut | Biodegradable piezoelectric ultrasonic transducer system |
| KR102197871B1 (ko) * | 2019-03-28 | 2021-01-04 | 이화여자대학교 산학협력단 | 엽산, 엽산 유도체, 또는 엽산 저해제를 이용한 줄기세포의 연골세포로의 분화 유도 방법 |
| KR102337350B1 (ko) * | 2019-11-22 | 2021-12-08 | 아주대학교산학협력단 | 내재성 전구세포 또는 줄기세포 포집능 및 포집된 세포의 혈관 분화 유도능을 갖는 주입형 하이드로겔 조성물 |
| US11745001B2 (en) | 2020-03-10 | 2023-09-05 | University Of Connecticut | Therapeutic bandage |
| US12491290B2 (en) | 2020-06-08 | 2025-12-09 | University Of Connecticut | Biodegradable piezoelectric composite materials |
| FR3116534B1 (fr) | 2020-11-23 | 2023-12-22 | Kiomed Pharma | Billes à base de chitosane, préparation, compositions et applications |
| US20230404765A1 (en) * | 2020-12-07 | 2023-12-21 | University Of Connecticut | A system and method for osteoarthritis treatment |
| CN114652895A (zh) * | 2020-12-23 | 2022-06-24 | 上海其胜生物制剂有限公司 | 一种可注射组织再生型壳聚糖复合凝胶支架的制备方法 |
| CN113663085B (zh) * | 2021-08-25 | 2023-12-15 | 福州市大福瑞生物科技有限公司 | 基于卤代环氧烷烃接枝制备皂苷-壳聚糖衍生物的方法及其应用 |
| CN114908038B (zh) * | 2022-06-06 | 2024-03-15 | 苏州大学 | 一种体外3d关节损伤模型及其构建与应用 |
| CN115154673B (zh) * | 2022-06-28 | 2023-07-14 | 北京航空航天大学宁波创新研究院 | 人工软骨植入物预成型体及制备方法和应用、类生人工软骨植入物胶原纤维原位构建方法 |
| PL443403A1 (pl) | 2023-01-03 | 2024-07-08 | Politechnika Gdańska | Hydrożelowy kompozyt na bazie chitozanu, sposób wytwarzania hydrożelowego kompozytu na bazie chitozanu oraz zastosowanie kompozytu w postaci biotuszu do tworzenia przestrzennych obiektów, zwłaszcza z wykorzystaniem technologii wytwarzania addytywnego, zwłaszcza celem prowadzenia hodowli komórkowych |
Family Cites Families (13)
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| AU3097999A (en) | 1998-03-18 | 1999-10-11 | University Of Pittsburgh | Chitosan-based composite materials containing glycosaminoglycan for cartilage repair |
| KR100375422B1 (ko) * | 1999-12-21 | 2003-03-10 | 한국과학기술연구원 | 다공성 키토산 구슬 및 그의 제조 방법 |
| JP2002209573A (ja) * | 2001-01-15 | 2002-07-30 | Toru Yamazaki | 細胞及び又は生体組織の担持体と移植体、及び担持方法 |
| JP3616344B2 (ja) * | 2001-03-29 | 2005-02-02 | 紳一郎 西村 | 軟骨細胞培養方法および軟骨組織再生基材 |
| WO2002078761A1 (fr) | 2001-03-30 | 2002-10-10 | Laboratoires Genevrier | Neo-tissu cartilagineux greffable |
| FR2822842B1 (fr) * | 2001-03-30 | 2004-11-19 | Genevrier Lab | Procede de preparation d'un neo-tissu cartilagineux |
| US8173171B2 (en) * | 2003-11-17 | 2012-05-08 | Taiwan Textile Research Institute | Hydrogel microparticle composition, application thereof and method for preparing the same |
| US7524514B2 (en) * | 2003-12-01 | 2009-04-28 | Tissue Engineering Consultants, Inc. | Biomimetic composition reinforced by a polyelectrolytic complex of hyaluronic acid and chitosan |
| CN101098718A (zh) * | 2004-12-20 | 2008-01-02 | 卡博格拉夫特有限公司 | 壳聚糖组合物 |
| SG10201500237TA (en) | 2008-01-30 | 2015-04-29 | Histogen Inc | Extracellular matrix compositions |
| EP2361640A1 (en) * | 2010-02-25 | 2011-08-31 | Université de Liège | Cell cultivation in chitosan alginate hydrogel beads |
| FR2963351B1 (fr) | 2010-07-30 | 2013-03-08 | Univ Claude Bernard Lyon | Particules formees d'un complexe polyelectrolyte de chitosane et d'un polysaccharide anionique, presentant une stabilite amelioree |
| FR2965278B1 (fr) | 2010-09-23 | 2014-10-10 | Univ Caen Basse Normandie | Procede d'obtention in vitro ou ex vivo de chondrocytes et leurs utilisations |
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2014
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2015
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- 2015-12-01 JP JP2017547081A patent/JP6821583B2/ja active Active
- 2015-12-01 US US15/532,020 patent/US10612001B2/en active Active
- 2015-12-01 CA CA2969285A patent/CA2969285C/fr active Active
- 2015-12-01 ES ES15817457T patent/ES2870505T3/es active Active
- 2015-12-01 WO PCT/FR2015/053271 patent/WO2016087762A1/fr not_active Ceased
- 2015-12-01 PT PT158174573T patent/PT3226923T/pt unknown
- 2015-12-01 EP EP15817457.3A patent/EP3226923B1/fr active Active
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2018
- 2018-01-23 FR FR1850498A patent/FR3062064B1/fr active Active
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2020
- 2020-03-25 US US16/829,634 patent/US11718828B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DK3226923T3 (da) | 2021-05-17 |
| EP3226923B1 (fr) | 2021-02-17 |
| FR3062064B1 (fr) | 2020-11-27 |
| CA2969285C (fr) | 2023-09-05 |
| US10612001B2 (en) | 2020-04-07 |
| US11718828B2 (en) | 2023-08-08 |
| US20200248144A1 (en) | 2020-08-06 |
| JP2017535405A (ja) | 2017-11-30 |
| WO2016087762A1 (fr) | 2016-06-09 |
| US20170306295A1 (en) | 2017-10-26 |
| FR3062064A1 (fr) | 2018-07-27 |
| EP3226923A1 (fr) | 2017-10-11 |
| PT3226923T (pt) | 2021-05-07 |
| JP6821583B2 (ja) | 2021-01-27 |
| FR3029116A1 (fr) | 2016-06-03 |
| CA2969285A1 (fr) | 2016-06-09 |
| FR3029116B1 (fr) | 2018-03-30 |
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