ES2183563T3 - Sistema de deteccion optico multicanal. - Google Patents

Sistema de deteccion optico multicanal.

Info

Publication number
ES2183563T3
ES2183563T3 ES99925705T ES99925705T ES2183563T3 ES 2183563 T3 ES2183563 T3 ES 2183563T3 ES 99925705 T ES99925705 T ES 99925705T ES 99925705 T ES99925705 T ES 99925705T ES 2183563 T3 ES2183563 T3 ES 2183563T3
Authority
ES
Spain
Prior art keywords
mixture
excitation
vessel
filters
chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99925705T
Other languages
English (en)
Inventor
Lee A Christel
M Allen Northrup
Kurt E Petersen
William A Mcmillan
Gregory T A Kovacs
Steven J Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cepheid
Original Assignee
Cepheid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cepheid filed Critical Cepheid
Application granted granted Critical
Publication of ES2183563T3 publication Critical patent/ES2183563T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/0303—Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/0332—Cuvette constructions with temperature control

Landscapes

  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Optical Communication System (AREA)
  • Optical Measuring Cells (AREA)

Abstract

Un aparato para interrogar ópticamente a una mezcla de reacción contenida en un vaso de reacción que tiene paredes de transmisión óptica primera y segunda, comprendiendo el aparato: a) una ranura para recibir el vaso; y b) conjuntos ópticos primero y segundo situados de tal modo que cuando se pone el vaso en la ranura, los conjuntos ópticos primero y segundo están en comunicación óptica con las paredes de transmisión óptica primera y segunda de las paredes del vaso, respectivamente; en que el primer conjunto óptico comprende: i) un primer alojamiento que tiene una primera ventana óptica; ii) al menos dos manantiales de luz para transmitir haces de excitación a la mezcla de reacción a través de la primera ventana; y iii)un primer juego de filtros para filtrar los haces de excitación de tal modo que cada uno de los haces tenga un margen de longitudes de onda de excitación sustancialmente distinto, en el que los manantiales de luz yel primer juego de filtros están fijados rígidamente al primer alojamiento; y en el que el segundo conjunto óptico comprende: i) un segundo alojamiento que tiene una segunda ventana óptica para recibir la luz emitida desde la mezcla; ii) al menos dos detectores para detectar la luz emitida; y iii)un segundo juego de filtros para separar la luz emitida en al menos dos márgenes de longitudes de onda de emisión y para dirigir la luz emitida en cada uno de los márgenes de longitudes de onda de emisión a uno respectivo de los detectores, en el que los detectores y el segundo juego de filtros están fijados rígidamente en el segundo alojamiento.
ES99925705T 1998-05-19 1999-05-19 Sistema de deteccion optico multicanal. Expired - Lifetime ES2183563T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8126098A 1998-05-19 1998-05-19

Publications (1)

Publication Number Publication Date
ES2183563T3 true ES2183563T3 (es) 2003-03-16

Family

ID=22163078

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99925705T Expired - Lifetime ES2183563T3 (es) 1998-05-19 1999-05-19 Sistema de deteccion optico multicanal.

Country Status (9)

Country Link
EP (1) EP1080364B1 (es)
JP (1) JP3957457B2 (es)
KR (1) KR100840949B1 (es)
AT (1) ATE228242T1 (es)
AU (1) AU746069B2 (es)
CA (1) CA2331678C (es)
DE (1) DE69904043T2 (es)
ES (1) ES2183563T3 (es)
WO (1) WO1999060380A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6660228B1 (en) 1998-03-02 2003-12-09 Cepheid Apparatus for performing heat-exchanging, chemical reactions
US6707555B1 (en) * 1998-10-15 2004-03-16 Sysmex Corporation Optical information measuring apparatus
US6403037B1 (en) 2000-02-04 2002-06-11 Cepheid Reaction vessel and temperature control system
KR20010008151A (ko) * 2000-11-13 2001-02-05 정두락 유니버설 시리얼 버스를 이용한 방사선 디지탈센서 연결보드
JP2003287491A (ja) * 2002-01-28 2003-10-10 Sysmex Corp 粒子分析装置および粒子分析方法
US9429509B2 (en) * 2002-01-28 2016-08-30 Sysmex Corporation Particle analyzer and particle analysis method
GB0209329D0 (en) * 2002-04-24 2002-06-05 Imp College Innovations Ltd A device
CN100472192C (zh) 2002-10-25 2009-03-25 爱科来株式会社 光源组件、受光组件以及使用了它们的多通道光检测装置
EP2284278A1 (en) 2003-04-04 2011-02-16 Roche Diagnostics GmbH Improved system for multi color real time PCR
US7170594B2 (en) * 2003-05-28 2007-01-30 Smiths Detection, Inc. Device for polymerase chain reactions
DE102008025865A1 (de) * 2008-05-29 2009-12-03 Lumitech Produktion Und Entwicklung Gmbh LED-Modul mit integrierten elektronischen Bauteilen für die Farbort- und Intensitätssteuerung
DE102010003365A1 (de) * 2010-03-26 2011-09-29 Micropelt Gmbh Vorrichtung zur Durchführung der PCR und PCR-Verfahren
DE102010048443B4 (de) * 2010-10-15 2015-05-21 Technische Universität Braunschweig Carolo-Wilhelmina Verfahren zur durchführung von zeitaufgelösten untersuchungen an zellproben
WO2015200926A1 (en) * 2014-06-27 2015-12-30 Pulse Heath Llc Fluorescence detection assembly
US10501788B2 (en) * 2015-02-06 2019-12-10 Life Technologies Corporation System and methods for calibrating binding dyes
CN106353295A (zh) * 2016-11-11 2017-01-25 中国科学院生物物理研究所 一种蛋白质热稳定分析仪
JP7021717B2 (ja) * 2019-03-12 2022-02-17 株式会社島津製作所 分光光度計
TWI715997B (zh) 2019-06-13 2021-01-11 新加坡商克雷多生物醫學私人有限公司 一種可即時偵測一種以上螢光訊號之聚合酶鏈式反應裝置
CN110806491B (zh) * 2019-11-15 2024-03-29 成都宜乐芯生物科技有限公司 一种全自动poct多重检测液相芯片系统
KR102412464B1 (ko) * 2020-05-29 2022-06-22 중앙대학교 산학협력단 피씨알 장치
CN111812215B (zh) * 2020-07-22 2021-06-29 南京航空航天大学 一种飞行器结构损伤的监测方法
DE102020216541A1 (de) 2020-12-23 2022-06-23 Robert Bosch Gesellschaft mit beschränkter Haftung Vorrichtung und Verfahren für eine Fluoreszenzmessung für eine Analyse einer biochemischen Probe
DE102022201532A1 (de) 2022-02-15 2023-08-17 Robert Bosch Gesellschaft mit beschränkter Haftung Verfahren zur Kalibrierung eines Analysesystems für Lab-on-Chip-Kartuschen
US20240167956A1 (en) * 2022-11-22 2024-05-23 10X Genomics, Inc. Systems and methods for imaging samples

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4074939A (en) * 1973-12-19 1978-02-21 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Apparatus for investigating fast chemical reactions by optical detection
US5073029A (en) * 1990-02-16 1991-12-17 Eqm Research, Inc. Multisource device for photometric analysis and associated chromogens
JPH04348258A (ja) * 1991-05-27 1992-12-03 Kowa Co 多チャンネル光学測定装置
DE4140411A1 (de) * 1991-12-07 1993-06-09 Hoechst Ag, 6230 Frankfurt, De Messeinrichtung zur bestimmung der konzentration von anorganischen und organischen verbindungen in einer probe
JPH05258784A (ja) * 1992-03-09 1993-10-08 Toshiba Lighting & Technol Corp 電気器具および端子装置
WO1995003537A1 (en) * 1993-07-26 1995-02-02 Biotechtronix, Inc. Colorimetric titration method and apparatus
US5397709A (en) * 1993-08-27 1995-03-14 Becton Dickinson And Company System for detecting bacterial growth in a plurality of culture vials
WO1995030139A1 (en) * 1994-04-29 1995-11-09 Perkin-Elmer Corporation System for real time detection of nucleic acid amplification products
US5589136A (en) * 1995-06-20 1996-12-31 Regents Of The University Of California Silicon-based sleeve devices for chemical reactions
AU738290B2 (en) * 1995-08-22 2001-09-13 Abraxis Bioscience, Llc Method and apparatus for determining characteristics of a sample in the presence of ambient light
JP3886153B2 (ja) * 1996-03-19 2007-02-28 ユニバーシティー オブ ユタ リサーチ ファンデーション レンズおよび連結可能なフローセル
JP3720458B2 (ja) * 1996-06-19 2005-11-30 オリンパス株式会社 分析装置

Also Published As

Publication number Publication date
AU4194099A (en) 1999-12-06
EP1080364A1 (en) 2001-03-07
DE69904043D1 (de) 2003-01-02
AU746069B2 (en) 2002-04-11
ATE228242T1 (de) 2002-12-15
JP2002515602A (ja) 2002-05-28
DE69904043T2 (de) 2003-07-31
WO1999060380A1 (en) 1999-11-25
CA2331678C (en) 2009-09-15
KR100840949B1 (ko) 2008-06-24
KR20010034860A (ko) 2001-04-25
EP1080364B1 (en) 2002-11-20
JP3957457B2 (ja) 2007-08-15
CA2331678A1 (en) 1999-11-25

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