ES2173471T3 - Analisis para homocisteina y homocisteina desulfurasa a partir de tricomonas viginalis de protozoos. - Google Patents

Analisis para homocisteina y homocisteina desulfurasa a partir de tricomonas viginalis de protozoos.

Info

Publication number
ES2173471T3
ES2173471T3 ES97937707T ES97937707T ES2173471T3 ES 2173471 T3 ES2173471 T3 ES 2173471T3 ES 97937707 T ES97937707 T ES 97937707T ES 97937707 T ES97937707 T ES 97937707T ES 2173471 T3 ES2173471 T3 ES 2173471T3
Authority
ES
Spain
Prior art keywords
homocysteine
viginalis
tricomones
protozoos
homocisteine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97937707T
Other languages
English (en)
Inventor
Graham Herbert Coombs
Jeremy Charles Mottram
David John Pritchard
Robert Stewart Campbell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Glasgow
Original Assignee
University of Glasgow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Glasgow filed Critical University of Glasgow
Application granted granted Critical
Publication of ES2173471T3 publication Critical patent/ES2173471T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • G01N33/6812Assays for specific amino acids
    • G01N33/6815Assays for specific amino acids containing sulfur, e.g. cysteine, cystine, methionine, homocysteine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN ENSAYO PARA DETERMINAR LOS NIVELES DE HOMOCISTEINA, CISTEINA, O - ACETIL - L - SERINA Y/O METIONINA EN UNA MUESTRA BIOLOGICA, UTILIZANDO UNA ENZIMA QUE CATALIZA LA DEGRADACION DE HOMOCISTEINA, CISTEINA, O ACETIL - L - SERINA Y/O METIONINA, SIENDO DICHA ENZIMA ESPECIFICAMENTE HOMOCISTEINA DESULFURASA, UN FRAGMENTO POLINUCLEOTIDICO QUE CODIFICA PARA HOMOCISTEINA DESULFURASA PROTOZOARIA, UN VECTOR RECOMBINANTE QUE COMPRENDE DICHO FRAGMENTO, CELULAS TRANSFORMADAS O EL POLIPEPTIDO DE HOMOCISTEINA DESULFURASA PROTOZOARIA. ASIMISMO, SE DESCRIBEN COMPOSICIONES FARMACEUTICAS QUE COMPRENDEN HOMOCISTEINA DESULFURASA PARA UTILIZACION EN MEDICINA O VETERINARIA.
ES97937707T 1996-08-23 1997-08-23 Analisis para homocisteina y homocisteina desulfurasa a partir de tricomonas viginalis de protozoos. Expired - Lifetime ES2173471T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9617683.9A GB9617683D0 (en) 1996-08-23 1996-08-23 Homocysteine desulphurase

Publications (1)

Publication Number Publication Date
ES2173471T3 true ES2173471T3 (es) 2002-10-16

Family

ID=10798850

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97937707T Expired - Lifetime ES2173471T3 (es) 1996-08-23 1997-08-23 Analisis para homocisteina y homocisteina desulfurasa a partir de tricomonas viginalis de protozoos.

Country Status (18)

Country Link
US (1) US6306618B1 (es)
EP (1) EP0932689B1 (es)
JP (1) JP3360833B2 (es)
CN (1) CN1200105C (es)
AT (1) ATE213777T1 (es)
AU (1) AU713545B2 (es)
BR (1) BR9711238A (es)
CA (1) CA2264189C (es)
DE (1) DE69710747T2 (es)
DK (1) DK0932689T3 (es)
ES (1) ES2173471T3 (es)
GB (1) GB9617683D0 (es)
IL (1) IL128578A (es)
NO (1) NO326477B1 (es)
NZ (1) NZ334518A (es)
PT (1) PT932689E (es)
WO (1) WO1998007872A1 (es)
ZA (1) ZA977582B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140102A (en) * 1997-07-24 2000-10-31 Anticancer, Inc. High specificity homocysteinases and genes therefor
US6468762B1 (en) 1997-07-24 2002-10-22 Anticancer, Inc. High specificity homocysteinases
US5985540A (en) * 1997-07-24 1999-11-16 Anticancer, Inc. High specificity homocysteine assays for biological samples
US6066467A (en) * 1997-07-24 2000-05-23 Anticancer, Inc. High specificity homocysteine assays for biological samples
US6174696B1 (en) * 1999-11-12 2001-01-16 Genzyme Corporation Method for the determination of homocysteine
JP4426725B2 (ja) * 1998-11-12 2010-03-03 ジェンザイム・コーポレーション ホモシステイン測定法
TW546475B (en) * 1998-12-07 2003-08-11 Daiichi Pure Chemicals Co Ltd A method for quantifying hydrogen sulfide or sulfide ion and a method for quantifying homocysteine or cysteine by using the method
ATE380253T1 (de) * 1999-02-01 2007-12-15 Anticancer Inc Homogene enzymatische bestimmungsmethode für vitamin b6
US6635438B2 (en) * 1999-11-02 2003-10-21 Catch, Inc. Enzymatic cycling assays for homocysteine and cystathionine
GB0008784D0 (en) * 2000-04-10 2000-05-31 Axis Shield Plc Assay
EP1849875B1 (en) * 2000-06-30 2008-11-19 Alfresa Pharma Corporation Method for determining total homocysteine
EP1456399B1 (en) * 2001-11-20 2006-07-05 Anticancer, Inc. Total cysteine assay
JP2005537022A (ja) * 2002-09-03 2005-12-08 アンチキャンサー インコーポレーテッド スクリーニングに適応できるホモシステインアッセイ
JP2006149203A (ja) * 2003-02-19 2006-06-15 Alfresa Pharma Corp ホモシステインの測定方法
GB0311804D0 (en) * 2003-05-22 2003-06-25 Univ Glasgow Improved homocysteine assay
CN105717309A (zh) * 2016-04-07 2016-06-29 广州市微生物研究所 一种检测同型半胱氨酸的方法及试剂盒
CN113957116B (zh) * 2021-11-01 2023-05-30 温州医科大学 基于含半胱氨酸脱硫酶大肠杆菌活细胞检测l-丝氨酸的方法
CN118029165A (zh) * 2024-04-12 2024-05-14 四川大学 改性羊毛纤维、制备方法、复合发泡材料及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4940658A (en) * 1986-11-20 1990-07-10 University Patents, Inc. Assay for sulfhydryl amino acids and methods for detecting and distinguishing cobalamin and folic acid deficency
PT726322E (pt) 1992-01-22 2003-09-30 Axis Shield Asa Analise para determinacao de homocisteina
US5715835A (en) 1992-11-19 1998-02-10 Anticancer, Inc. Methods for treating and reducing the potential for cardiovascular disease using methioninase compositions
PT668933E (pt) 1992-11-19 2003-02-28 Anticancer Inc Utilizacao de metioninase como agente anti-tumor em qimioterapia anti-metionina
US6066467A (en) * 1997-07-24 2000-05-23 Anticancer, Inc. High specificity homocysteine assays for biological samples
US6140102A (en) 1997-07-24 2000-10-31 Anticancer, Inc. High specificity homocysteinases and genes therefor
US5985540A (en) 1997-07-24 1999-11-16 Anticancer, Inc. High specificity homocysteine assays for biological samples
US5885767A (en) 1998-05-22 1999-03-23 Biocatalytics, Inc. Methods and compositions for quantitating L-homocysteine and/or l-methionine in a solution

Also Published As

Publication number Publication date
AU4024097A (en) 1998-03-06
EP0932689B1 (en) 2002-02-27
CA2264189C (en) 2002-07-09
WO1998007872A1 (en) 1998-02-26
JP3360833B2 (ja) 2003-01-07
BR9711238A (pt) 2000-01-18
CN1200105C (zh) 2005-05-04
US6306618B1 (en) 2001-10-23
DE69710747D1 (en) 2002-04-04
ATE213777T1 (de) 2002-03-15
GB9617683D0 (en) 1996-10-02
EP0932689A1 (en) 1999-08-04
NO990823L (no) 1999-04-20
NO990823D0 (no) 1999-02-22
NZ334518A (en) 2000-08-25
DK0932689T3 (da) 2002-06-17
ZA977582B (en) 1998-02-23
AU713545B2 (en) 1999-12-02
CN1231696A (zh) 1999-10-13
PT932689E (pt) 2002-08-30
DE69710747T2 (de) 2002-10-24
NO326477B1 (no) 2008-12-15
CA2264189A1 (en) 1998-02-26
IL128578A0 (en) 2000-01-31
IL128578A (en) 2007-05-15
JP2000502262A (ja) 2000-02-29

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