ES2172943T3 - Procedimiento para la preparacion de una sal de acido (s)-3,4-epoxibutirico opticamente activa. - Google Patents

Procedimiento para la preparacion de una sal de acido (s)-3,4-epoxibutirico opticamente activa.

Info

Publication number
ES2172943T3
ES2172943T3 ES98959263T ES98959263T ES2172943T3 ES 2172943 T3 ES2172943 T3 ES 2172943T3 ES 98959263 T ES98959263 T ES 98959263T ES 98959263 T ES98959263 T ES 98959263T ES 2172943 T3 ES2172943 T3 ES 2172943T3
Authority
ES
Spain
Prior art keywords
salt
preparation
following formula
expressed
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98959263T
Other languages
English (en)
Inventor
Ho Sung Yu
Jae Young Bae
Yik Haeng Cho
Young Mi Park
Il Suk Byun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lotte Fine Chemical Co Ltd
Original Assignee
Samsung Fine Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samsung Fine Chemicals Co Ltd filed Critical Samsung Fine Chemicals Co Ltd
Application granted granted Critical
Publication of ES2172943T3 publication Critical patent/ES2172943T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D301/00Preparation of oxiranes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

un procedimiento para la preparación de sal de ácido (s)-3,4-epoxibutírico expresado mediante la fórmula 1 siguiente, en donde la reacción de apertura de anillo de (s)- 3-hidroxibutirolactona expresado por la fórmula 2 siguiente se lleva a cabo utilizando hidroácido-ácido carboxílico para dar un derivado butírico expresado por la fórmula 3 siguiente y luego se epoxida dicho derivado en presencia de una base y solución acuosa a la gama de temperatura de -20ºC- 100ºC. **fórmula** en donde R1 representa átomo de metal alcalino, átomo de metal alcalinotérreo, grupo alquilamina o grupo amínico cuaternario; R2 representa grupo halógeno; R3 representa átomo de hidrógeno o grupo acilo alifático.
ES98959263T 1998-07-24 1998-12-08 Procedimiento para la preparacion de una sal de acido (s)-3,4-epoxibutirico opticamente activa. Expired - Lifetime ES2172943T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019980029911A KR100332703B1 (ko) 1998-07-24 1998-07-24 광학활성을갖는(s)-3,4-에폭시부티르산염의제조방법

Publications (1)

Publication Number Publication Date
ES2172943T3 true ES2172943T3 (es) 2002-10-01

Family

ID=19545118

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98959263T Expired - Lifetime ES2172943T3 (es) 1998-07-24 1998-12-08 Procedimiento para la preparacion de una sal de acido (s)-3,4-epoxibutirico opticamente activa.

Country Status (10)

Country Link
US (1) US6284902B1 (es)
EP (1) EP1109797B1 (es)
JP (1) JP3333184B2 (es)
KR (1) KR100332703B1 (es)
CN (1) CN1125059C (es)
CA (1) CA2338758A1 (es)
DE (1) DE69804515T2 (es)
ES (1) ES2172943T3 (es)
IN (1) IN187642B (es)
WO (1) WO2000005227A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4589508B2 (ja) * 2000-09-28 2010-12-01 花王株式会社 スルホアルキル化剤の製造法
KR100846673B1 (ko) * 2006-03-22 2008-07-16 엔자이텍 주식회사 엘-카르니틴의 제조방법
CN109265336B (zh) * 2018-09-26 2021-05-07 大丰跃龙化学有限公司 一种合成γ-氯代丁酸的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1189069B (it) * 1986-03-14 1988-01-28 Donegani Guido Ist Processo per la preparazione biotecnologica della l(-)-carnitina cloruro
JP2834501B2 (ja) * 1989-11-25 1998-12-09 鐘淵化学工業株式会社 3,4―エポキシ酪酸エステルの製法および中間体
US5097049A (en) * 1990-05-03 1992-03-17 Eli Lilly And Company Process and intermediates for chiral epoxides
JP2710688B2 (ja) * 1990-10-09 1998-02-10 鐘淵化学工業株式会社 4―ブロモ―3―ヒドロキシ酪酸エステル誘導体の製造法
US5998633A (en) * 1996-07-29 1999-12-07 Warner-Lambert Company Process for the synthesis of protected esters of (S)-3,4-dihydroxybutyric acid

Also Published As

Publication number Publication date
EP1109797A1 (en) 2001-06-27
JP3333184B2 (ja) 2002-10-07
WO2000005227A1 (en) 2000-02-03
DE69804515T2 (de) 2002-11-07
DE69804515D1 (de) 2002-05-02
CN1125059C (zh) 2003-10-22
EP1109797B1 (en) 2002-03-27
US6284902B1 (en) 2001-09-04
IN187642B (es) 2002-06-01
KR20000009466A (ko) 2000-02-15
KR100332703B1 (ko) 2002-08-27
CA2338758A1 (en) 2000-02-03
JP2002521379A (ja) 2002-07-16
CN1322199A (zh) 2001-11-14

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