ES2141089T3 - Gp75 como vacuna tumoral para melanoma. - Google Patents
Gp75 como vacuna tumoral para melanoma.Info
- Publication number
- ES2141089T3 ES2141089T3 ES91908003T ES91908003T ES2141089T3 ES 2141089 T3 ES2141089 T3 ES 2141089T3 ES 91908003 T ES91908003 T ES 91908003T ES 91908003 T ES91908003 T ES 91908003T ES 2141089 T3 ES2141089 T3 ES 2141089T3
- Authority
- ES
- Spain
- Prior art keywords
- stimulate
- fragment
- molecula
- vaccines
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102100030310 5,6-dihydroxyindole-2-carboxylic acid oxidase Human genes 0.000 title abstract 5
- 101000773083 Homo sapiens 5,6-dihydroxyindole-2-carboxylic acid oxidase Proteins 0.000 title abstract 5
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000001441 melanoma Diseases 0.000 title 1
- 150000001413 amino acids Chemical group 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y110/00—Oxidoreductases acting on diphenols and related substances as donors (1.10)
- C12Y110/03—Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
- C12Y110/03001—Catechol oxidase (1.10.3.1), i.e. tyrosinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0055—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
- C12N9/0057—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
- C12N9/0059—Catechol oxidase (1.10.3.1), i.e. tyrosinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/16—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced pteridine as one donor, and incorporation of one atom of oxygen (1.14.16)
- C12Y114/16002—Tyrosine 3-monooxygenase (1.14.16.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/18—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with another compound as one donor, and incorporation of one atom of oxygen (1.14.18)
- C12Y114/18001—Tyrosinase (1.14.18.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
LA PRESENTE INVENCION SUMINISTRA UNA MOLECULA DE ACIDO NUCLEICO AISLADA CUYA SECUENCIA CODIFICA LA SECUENCIA DE ACIDO AMINO PARA GP75 O UN FRAGMENTO DE LA MISMA. LA INVENCION SUMINISTRA ADEMAS UNA MOLECULA DE CDNA AISLADA DE LA MOLECULA DEL ACIDO NUCLEICO GP75 O UN FRAGMENTO DE LA MISMA Y LA SECUENCIA DE ACIDO AMINO DERIVADA DE LA MISMA. ESTA INVENCION TAMBIEN SUMINISTRA VACUNAS PARA ESTIMULAR O MEJORAR, EN UN SUJETO A QUIEN SE HA SUMINISTRADO LA VACUNA, LA PRODUCCION DE ANTICUERPOS DIRIGIDOS EN CONTRA DE GP75. LA INVENCION SUMINISTRA ADEMAS METODOS PARA USAR LAS VACUNAS DE LA INVENCION PARA ESTIMULAR Y MEJORAR LA PRODUCCION DE ANTICUERPOS CONTRA GP75 ASI COMO PARA TRATAR, EVITAR O RETARDAR LA PRESENCIA DEL CANCER.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49743190A | 1990-03-22 | 1990-03-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2141089T3 true ES2141089T3 (es) | 2000-03-16 |
Family
ID=23976841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91908003T Expired - Lifetime ES2141089T3 (es) | 1990-03-22 | 1991-03-22 | Gp75 como vacuna tumoral para melanoma. |
Country Status (21)
Country | Link |
---|---|
US (2) | US6168946B1 (es) |
EP (2) | EP0965640A1 (es) |
JP (2) | JP3336006B2 (es) |
AT (1) | ATE187493T1 (es) |
AU (1) | AU660412B2 (es) |
CA (1) | CA2078773C (es) |
CZ (1) | CZ290278B6 (es) |
DE (1) | DE69131829T2 (es) |
DK (1) | DK0522078T3 (es) |
ES (1) | ES2141089T3 (es) |
FI (1) | FI113786B (es) |
GR (1) | GR3032804T3 (es) |
HK (1) | HK1014732A1 (es) |
HU (1) | HU218416B (es) |
IE (2) | IE910820A1 (es) |
NO (1) | NO311366B1 (es) |
NZ (1) | NZ237532A (es) |
PL (3) | PL168235B1 (es) |
PT (1) | PT97103B (es) |
SK (1) | SK282873B6 (es) |
WO (1) | WO1991014775A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE910820A1 (en) * | 1990-03-22 | 1991-09-25 | Sloan Kettering Inst Cancer | Gp75 as a tumor vaccine for melanoma |
US7041801B1 (en) * | 1995-06-07 | 2006-05-09 | Vanderbilt University | Antibodies binding to polypeptides encoded by developmentally-regulated endothelial cell locus-1 |
US5840839A (en) * | 1996-02-09 | 1998-11-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein |
US7015312B1 (en) | 1996-02-09 | 2006-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Antibodies to the protein product encoded by ORF3 of the TRP-1 gene and compositions and kits thereof |
US6083703A (en) * | 1996-02-09 | 2000-07-04 | The United States Of America As Represented By The Department Of Health And Human Services | Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes |
US7001600B1 (en) | 1996-02-09 | 2006-02-21 | The United States Of America As Represented By The Secretary Of Health And Human Services | Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes |
AU2001241533A1 (en) * | 2000-02-15 | 2001-08-27 | The Regents Of The University Of California | A universal vaccine and method for treating cancer employing telomerase reverse transcriptase |
US6613534B2 (en) | 2001-03-20 | 2003-09-02 | Wake Forest University Health Sciences | MAP-2 as a determinant of metastatic potential |
US20030113919A1 (en) * | 2001-08-17 | 2003-06-19 | Aventis Pasteur, Ltd. | Immunogenic targets for melanoma |
US20030157720A1 (en) * | 2002-02-06 | 2003-08-21 | Expression Technologies Inc. | Protein standard for estimating size and mass |
EP2171071B1 (en) | 2007-06-15 | 2015-08-05 | Genelux Corporation | Vaccinia virus vectors encoding a sodium-dependent transporter protein for imaging and/or treatment of tumors |
CN101970500B (zh) | 2008-03-12 | 2013-08-14 | 伊姆克罗尼责任有限公司 | 抗tyrp1抗体 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2504010B1 (fr) * | 1981-04-15 | 1985-10-25 | Sanofi Sa | Medicaments anticancereux contenant la chaine a de la ricine associee a un anticorps antimelanome et procede pour leur preparation |
US4808704A (en) * | 1981-09-30 | 1989-02-28 | Sloan-Kettering Institute For Cancer Research | Monoclonal antibodies to cell surface antigens of human malignant melanoma |
US4806628A (en) * | 1982-11-30 | 1989-02-21 | Sloan-Kettering Institute For Cancer Research | Monoclonal antibodies against melanocytes |
US4591572A (en) * | 1983-04-01 | 1986-05-27 | Sloan-Kettering Institute For Cancer Research | Pigmentation associated, differentiation antigen of human melanoma and autologous antibody |
USH819H (en) * | 1984-04-30 | 1990-09-04 | The United States Of America As Represented By The Secretary Of Energy | Palladium-109 labeled anti-melanoma monoclonal antibodies |
US4851510A (en) * | 1984-11-30 | 1989-07-25 | Wadley Technologies, Inc. | Monoclonal antibodies to novel melanoma-associated antigens |
US4798790A (en) * | 1985-07-18 | 1989-01-17 | Sloan-Kettering Institute | Monoclonal antibody specific for a pigmentation associated antigen |
US5262177A (en) * | 1986-02-07 | 1993-11-16 | Oncogen | Recombinant viruses encoding the human melanoma-associated antigen |
US5141742A (en) * | 1986-02-07 | 1992-08-25 | Oncogen | Vaccines against melanoma |
US5009995A (en) * | 1986-10-27 | 1991-04-23 | Sloan-Kettering Institute For Cancer Research | Monoclonal antibodies to melanoma cells |
US5059523A (en) * | 1988-05-02 | 1991-10-22 | Sloan-Kettering Institute For Cancer Research | Cell-surface glycoproteins of human sarcomas |
US5009495A (en) * | 1989-05-26 | 1991-04-23 | Williams Robert D | Hinge for eyeglasses |
JP3859695B2 (ja) | 1989-08-04 | 2006-12-20 | バーレックス ラボラトリーズ インコーポレイテッド | C―erbB―2外部ドメイン:GP75 |
IE910820A1 (en) * | 1990-03-22 | 1991-09-25 | Sloan Kettering Inst Cancer | Gp75 as a tumor vaccine for melanoma |
US5262117A (en) * | 1990-10-12 | 1993-11-16 | Centro Sviluppo Settori Impiego S.R.L. | Process for preparing thermoinsulating and/or structural formed articles and products so obtained |
US6180604B1 (en) * | 1996-08-21 | 2001-01-30 | Micrologix Biotech Inc. | Compositions and methods for treating infections using analogues of indolicidin |
-
1991
- 1991-03-12 IE IE082091A patent/IE910820A1/en not_active IP Right Cessation
- 1991-03-12 IE IE20000918A patent/IE20000918A1/en not_active IP Right Cessation
- 1991-03-21 NZ NZ237532A patent/NZ237532A/xx unknown
- 1991-03-21 CZ CS1991760A patent/CZ290278B6/cs not_active IP Right Cessation
- 1991-03-21 PT PT97103A patent/PT97103B/pt not_active IP Right Cessation
- 1991-03-21 SK SK760-91A patent/SK282873B6/sk unknown
- 1991-03-22 DE DE69131829T patent/DE69131829T2/de not_active Revoked
- 1991-03-22 CA CA002078773A patent/CA2078773C/en not_active Expired - Fee Related
- 1991-03-22 PL PL91289550A patent/PL168235B1/pl not_active IP Right Cessation
- 1991-03-22 PL PL91307929A patent/PL169105B1/pl not_active IP Right Cessation
- 1991-03-22 DK DK91908003T patent/DK0522078T3/da active
- 1991-03-22 PL PL91307930A patent/PL169168B1/pl not_active IP Right Cessation
- 1991-03-22 WO PCT/US1991/001942 patent/WO1991014775A1/en not_active Application Discontinuation
- 1991-03-22 AU AU76906/91A patent/AU660412B2/en not_active Ceased
- 1991-03-22 EP EP99109256A patent/EP0965640A1/en not_active Withdrawn
- 1991-03-22 AT AT91908003T patent/ATE187493T1/de not_active IP Right Cessation
- 1991-03-22 EP EP91908003A patent/EP0522078B1/en not_active Revoked
- 1991-03-22 HU HU9203009A patent/HU218416B/hu unknown
- 1991-03-22 ES ES91908003T patent/ES2141089T3/es not_active Expired - Lifetime
- 1991-03-22 JP JP50783191A patent/JP3336006B2/ja not_active Expired - Fee Related
-
1992
- 1992-09-21 NO NO19923659A patent/NO311366B1/no unknown
- 1992-09-21 FI FI924222A patent/FI113786B/fi active
-
1995
- 1995-03-24 US US08/409,794 patent/US6168946B1/en not_active Expired - Lifetime
-
1998
- 1998-12-28 HK HK98116009A patent/HK1014732A1/xx not_active IP Right Cessation
-
2000
- 2000-02-29 GR GR20000400507T patent/GR3032804T3/el not_active IP Right Cessation
-
2001
- 2001-12-25 JP JP2001391870A patent/JP2002241314A/ja active Pending
-
2004
- 2004-06-25 US US10/877,489 patent/US20050037462A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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