ES2141089T3 - Gp75 como vacuna tumoral para melanoma. - Google Patents

Gp75 como vacuna tumoral para melanoma.

Info

Publication number
ES2141089T3
ES2141089T3 ES91908003T ES91908003T ES2141089T3 ES 2141089 T3 ES2141089 T3 ES 2141089T3 ES 91908003 T ES91908003 T ES 91908003T ES 91908003 T ES91908003 T ES 91908003T ES 2141089 T3 ES2141089 T3 ES 2141089T3
Authority
ES
Spain
Prior art keywords
stimulate
fragment
molecula
vaccines
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91908003T
Other languages
English (en)
Inventor
Alan N Houghton
Setaluri Vijayasaradhi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Memorial Sloan Kettering Cancer Center
Original Assignee
Sloan Kettering Institute for Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23976841&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2141089(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sloan Kettering Institute for Cancer Research filed Critical Sloan Kettering Institute for Cancer Research
Application granted granted Critical
Publication of ES2141089T3 publication Critical patent/ES2141089T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y110/00Oxidoreductases acting on diphenols and related substances as donors (1.10)
    • C12Y110/03Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
    • C12Y110/03001Catechol oxidase (1.10.3.1), i.e. tyrosinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0055Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
    • C12N9/0057Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
    • C12N9/0059Catechol oxidase (1.10.3.1), i.e. tyrosinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/16Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced pteridine as one donor, and incorporation of one atom of oxygen (1.14.16)
    • C12Y114/16002Tyrosine 3-monooxygenase (1.14.16.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/18Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with another compound as one donor, and incorporation of one atom of oxygen (1.14.18)
    • C12Y114/18001Tyrosinase (1.14.18.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA PRESENTE INVENCION SUMINISTRA UNA MOLECULA DE ACIDO NUCLEICO AISLADA CUYA SECUENCIA CODIFICA LA SECUENCIA DE ACIDO AMINO PARA GP75 O UN FRAGMENTO DE LA MISMA. LA INVENCION SUMINISTRA ADEMAS UNA MOLECULA DE CDNA AISLADA DE LA MOLECULA DEL ACIDO NUCLEICO GP75 O UN FRAGMENTO DE LA MISMA Y LA SECUENCIA DE ACIDO AMINO DERIVADA DE LA MISMA. ESTA INVENCION TAMBIEN SUMINISTRA VACUNAS PARA ESTIMULAR O MEJORAR, EN UN SUJETO A QUIEN SE HA SUMINISTRADO LA VACUNA, LA PRODUCCION DE ANTICUERPOS DIRIGIDOS EN CONTRA DE GP75. LA INVENCION SUMINISTRA ADEMAS METODOS PARA USAR LAS VACUNAS DE LA INVENCION PARA ESTIMULAR Y MEJORAR LA PRODUCCION DE ANTICUERPOS CONTRA GP75 ASI COMO PARA TRATAR, EVITAR O RETARDAR LA PRESENCIA DEL CANCER.
ES91908003T 1990-03-22 1991-03-22 Gp75 como vacuna tumoral para melanoma. Expired - Lifetime ES2141089T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49743190A 1990-03-22 1990-03-22

Publications (1)

Publication Number Publication Date
ES2141089T3 true ES2141089T3 (es) 2000-03-16

Family

ID=23976841

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91908003T Expired - Lifetime ES2141089T3 (es) 1990-03-22 1991-03-22 Gp75 como vacuna tumoral para melanoma.

Country Status (21)

Country Link
US (2) US6168946B1 (es)
EP (2) EP0965640A1 (es)
JP (2) JP3336006B2 (es)
AT (1) ATE187493T1 (es)
AU (1) AU660412B2 (es)
CA (1) CA2078773C (es)
CZ (1) CZ290278B6 (es)
DE (1) DE69131829T2 (es)
DK (1) DK0522078T3 (es)
ES (1) ES2141089T3 (es)
FI (1) FI113786B (es)
GR (1) GR3032804T3 (es)
HK (1) HK1014732A1 (es)
HU (1) HU218416B (es)
IE (2) IE910820A1 (es)
NO (1) NO311366B1 (es)
NZ (1) NZ237532A (es)
PL (3) PL168235B1 (es)
PT (1) PT97103B (es)
SK (1) SK282873B6 (es)
WO (1) WO1991014775A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE910820A1 (en) * 1990-03-22 1991-09-25 Sloan Kettering Inst Cancer Gp75 as a tumor vaccine for melanoma
US7041801B1 (en) * 1995-06-07 2006-05-09 Vanderbilt University Antibodies binding to polypeptides encoded by developmentally-regulated endothelial cell locus-1
US5840839A (en) * 1996-02-09 1998-11-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein
US7015312B1 (en) 1996-02-09 2006-03-21 The United States Of America As Represented By The Department Of Health And Human Services Antibodies to the protein product encoded by ORF3 of the TRP-1 gene and compositions and kits thereof
US6083703A (en) * 1996-02-09 2000-07-04 The United States Of America As Represented By The Department Of Health And Human Services Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes
US7001600B1 (en) 1996-02-09 2006-02-21 The United States Of America As Represented By The Secretary Of Health And Human Services Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes
AU2001241533A1 (en) * 2000-02-15 2001-08-27 The Regents Of The University Of California A universal vaccine and method for treating cancer employing telomerase reverse transcriptase
US6613534B2 (en) 2001-03-20 2003-09-02 Wake Forest University Health Sciences MAP-2 as a determinant of metastatic potential
US20030113919A1 (en) * 2001-08-17 2003-06-19 Aventis Pasteur, Ltd. Immunogenic targets for melanoma
US20030157720A1 (en) * 2002-02-06 2003-08-21 Expression Technologies Inc. Protein standard for estimating size and mass
EP2171071B1 (en) 2007-06-15 2015-08-05 Genelux Corporation Vaccinia virus vectors encoding a sodium-dependent transporter protein for imaging and/or treatment of tumors
CN101970500B (zh) 2008-03-12 2013-08-14 伊姆克罗尼责任有限公司 抗tyrp1抗体

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2504010B1 (fr) * 1981-04-15 1985-10-25 Sanofi Sa Medicaments anticancereux contenant la chaine a de la ricine associee a un anticorps antimelanome et procede pour leur preparation
US4808704A (en) * 1981-09-30 1989-02-28 Sloan-Kettering Institute For Cancer Research Monoclonal antibodies to cell surface antigens of human malignant melanoma
US4806628A (en) * 1982-11-30 1989-02-21 Sloan-Kettering Institute For Cancer Research Monoclonal antibodies against melanocytes
US4591572A (en) * 1983-04-01 1986-05-27 Sloan-Kettering Institute For Cancer Research Pigmentation associated, differentiation antigen of human melanoma and autologous antibody
USH819H (en) * 1984-04-30 1990-09-04 The United States Of America As Represented By The Secretary Of Energy Palladium-109 labeled anti-melanoma monoclonal antibodies
US4851510A (en) * 1984-11-30 1989-07-25 Wadley Technologies, Inc. Monoclonal antibodies to novel melanoma-associated antigens
US4798790A (en) * 1985-07-18 1989-01-17 Sloan-Kettering Institute Monoclonal antibody specific for a pigmentation associated antigen
US5262177A (en) * 1986-02-07 1993-11-16 Oncogen Recombinant viruses encoding the human melanoma-associated antigen
US5141742A (en) * 1986-02-07 1992-08-25 Oncogen Vaccines against melanoma
US5009995A (en) * 1986-10-27 1991-04-23 Sloan-Kettering Institute For Cancer Research Monoclonal antibodies to melanoma cells
US5059523A (en) * 1988-05-02 1991-10-22 Sloan-Kettering Institute For Cancer Research Cell-surface glycoproteins of human sarcomas
US5009495A (en) * 1989-05-26 1991-04-23 Williams Robert D Hinge for eyeglasses
JP3859695B2 (ja) 1989-08-04 2006-12-20 バーレックス ラボラトリーズ インコーポレイテッド C―erbB―2外部ドメイン:GP75
IE910820A1 (en) * 1990-03-22 1991-09-25 Sloan Kettering Inst Cancer Gp75 as a tumor vaccine for melanoma
US5262117A (en) * 1990-10-12 1993-11-16 Centro Sviluppo Settori Impiego S.R.L. Process for preparing thermoinsulating and/or structural formed articles and products so obtained
US6180604B1 (en) * 1996-08-21 2001-01-30 Micrologix Biotech Inc. Compositions and methods for treating infections using analogues of indolicidin

Also Published As

Publication number Publication date
CA2078773C (en) 2001-07-03
CZ290278B6 (cs) 2002-07-17
ATE187493T1 (de) 1999-12-15
FI113786B (fi) 2004-06-15
PT97103A (pt) 1991-12-31
NO923659D0 (no) 1992-09-21
JPH06501837A (ja) 1994-03-03
PL289550A1 (en) 1992-07-27
AU7690691A (en) 1991-10-21
NZ237532A (en) 1993-03-26
FI924222A (fi) 1992-09-21
IE910820A1 (en) 1991-09-25
SK282873B6 (sk) 2003-01-09
PL168235B1 (pl) 1996-01-31
EP0522078B1 (en) 1999-12-08
PT97103B (pt) 1999-02-26
GR3032804T3 (en) 2000-06-30
FI924222A0 (fi) 1992-09-21
DE69131829D1 (de) 2000-01-13
AU660412B2 (en) 1995-06-29
US6168946B1 (en) 2001-01-02
IE20000918A1 (en) 2001-05-30
HUT62934A (en) 1993-06-28
EP0522078A1 (en) 1993-01-13
WO1991014775A1 (en) 1991-10-03
CA2078773A1 (en) 1991-09-23
HK1014732A1 (en) 1999-09-30
JP3336006B2 (ja) 2002-10-21
CS76091A3 (en) 1992-02-19
PL169168B1 (pl) 1996-06-28
DE69131829T2 (de) 2000-06-15
JP2002241314A (ja) 2002-08-28
PL169105B1 (pl) 1996-06-28
US20050037462A1 (en) 2005-02-17
NO923659L (no) 1992-11-06
NO311366B1 (no) 2001-11-19
EP0522078A4 (en) 1993-05-26
EP0965640A1 (en) 1999-12-22
HU218416B (hu) 2000-08-28
DK0522078T3 (da) 2000-06-13

Similar Documents

Publication Publication Date Title
MX2020010458A (es) Conjugados de camptotecina-peptido.
ES2141089T3 (es) Gp75 como vacuna tumoral para melanoma.
MX2020009366A (es) Anticuerpos anti-cd73 y usos de los mismos.
EA200800268A1 (ru) КОМБИНИРОВАННАЯ ТЕРАПИЯ АНТИТЕЛОМ ПРОТИВ CTLA-4 И СОДЕРЖАЩИМ CpG-МОТИВ СИНТЕТИЧЕСКИМ ОЛИГОДЕЗОКСИНУКЛЕОТИДОМ ДЛЯ ЛЕЧЕНИЯ ЗЛОКАЧЕСТВЕННОЙ ОПУХОЛИ
MX2022003930A (es) Conjugados de péptido de camptotecina.
DE60044665D1 (de) Her2/neu fusionsproteine
CY1107628T1 (el) Ανθρωπινα ctla-4 αντισωματα και χρησεις αυτων
CR8444A (es) Immunogenic peptide carrier conjugates and methods of producing same
MX2022011676A (es) Proteinas de fusion de il12 con enmascaramiento y metodos para su uso.
HK1112367A1 (en) Survivin peptide vaccine
CY1117129T1 (el) Συγκεκριμενες φωσφορικες ενωσεις αμυναλκιλικου γλυκοζαμινιδιου και η χρηση τους
DE69739385D1 (de) Verbesserte impfstoffe
WO2023049636A3 (en) Cancer therapy compositions and uses thereof
MX2024002238A (es) Anticuerpos anti-ccr8 y uso de los mismos.
EA202192757A1 (ru) Способ лечения опухолей
CY1105179T1 (el) Φαρμακα για την ανοσοθepαπεια κακοηθων ογκων
MX2021010862A (es) Arn terapeutico para el cancer de prostata.
ZA202110285B (en) Antibodies and methods of use
BR0316132A (pt) Método para estimular o crescimento de cabelo utilizando benzopiranos
UY26170A1 (es) Antigeno (c42) asociados a tumores
UA83989C2 (ru) Выделенный пептид, который стимулирует противоопухолевый иммунный ответ, фармацевтическая композиция на его основе и ее применение
ATE328082T1 (de) Verkürztes bard1 protein und dessen diagnostische und therapeutische anwendungen
EA202193035A1 (ru) Материалы и способы для модуляции иммунитета, опосредованного т-клетками
UY26127A1 (es) Antígeno asociado con tumores
EA202191761A1 (ru) Новые конъюгированные молекулы нуклеиновой кислоты и их применение

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 522078

Country of ref document: ES