ES2073292T3 - Preparacion de acidos benzoicos trisustituidos y compuestos intermedios. - Google Patents

Preparacion de acidos benzoicos trisustituidos y compuestos intermedios.

Info

Publication number
ES2073292T3
ES2073292T3 ES92905867T ES92905867T ES2073292T3 ES 2073292 T3 ES2073292 T3 ES 2073292T3 ES 92905867 T ES92905867 T ES 92905867T ES 92905867 T ES92905867 T ES 92905867T ES 2073292 T3 ES2073292 T3 ES 2073292T3
Authority
ES
Spain
Prior art keywords
preparation
trisustituded
intermediate compounds
benzoic acids
benzoic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92905867T
Other languages
English (en)
Inventor
Richard W Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Application granted granted Critical
Publication of ES2073292T3 publication Critical patent/ES2073292T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/24—Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE PRESENTAN COMPUESTOS QUE TIENEN LA FORMULA ESTRUCTURAL (A) EN DONDE R ES HIDROGENO, HALOGENO O ALKILO C1-C2 Y R2 ES ALKILO C1-C4 QUE SE PREPARAN HACIENDO REACCIONAR UN MOL DE UN COMPUESTO DE FENOL QUE TENGA LA FORMULA ESTRUCTURAL (B), EN DONDE R Y R2 SON COMO SE HAN DEFINIDO, CON UN MOL DE ACIDO DE LEWIS PARA FORMAR UN COMPLEJO Y POR LO MENOS DOS MOLES, CADA UNO DE HALURO DE ACETILO Y UN ACIDO DE LEWIS SIEMPRE Y CUANDO SE HAGAN REACCIONAR EL FENOL Y POR LO MENOS UN MOL DEL ACIDO DE LEWIS PARA FORMAR UN COMPLEJO ANTES DE QUE EL FENOL REACCIONE CON UN COMPLEJO DE HALURO DE ACETILO Y DEL ACIDO DE LEWIS. SE PRESENTAN COMPUESTOS QUE TIENEN LAS FORMULAS (C), (D), (E) O (F) EN QUE R Y R2 SE HAN DEFINIDO ARRIBA Y R1 ES ALKILO C1-C4, HALOALKILO C1-C4, -CH2CH2OCH3, -CH2CH2OC2H5, -CH2CH2SCH3 O -CH2CH2SC2H5 Y R2 ES ALKILO C1-C4.
ES92905867T 1991-02-04 1992-01-23 Preparacion de acidos benzoicos trisustituidos y compuestos intermedios. Expired - Lifetime ES2073292T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/650,337 US5101065A (en) 1991-02-04 1991-02-04 Acetophenone intermediates

Publications (1)

Publication Number Publication Date
ES2073292T3 true ES2073292T3 (es) 1995-08-01

Family

ID=24608478

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92905867T Expired - Lifetime ES2073292T3 (es) 1991-02-04 1992-01-23 Preparacion de acidos benzoicos trisustituidos y compuestos intermedios.

Country Status (10)

Country Link
US (1) US5101065A (es)
EP (1) EP0570488B1 (es)
AT (1) ATE123766T1 (es)
BR (1) BR9205584A (es)
DE (1) DE69202970T2 (es)
DK (1) DK0570488T3 (es)
ES (1) ES2073292T3 (es)
HU (1) HU217447B (es)
WO (1) WO1992013834A1 (es)
ZA (1) ZA92754B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2135176C1 (ru) * 1993-12-14 1999-08-27 Эли Лилли Энд Компани Водорастворенный комплекс включения соединений бензотиофена с водорастворимым циклодекстрином, способ его получения и фармацевтическая композиция

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE34545B1 (en) * 1969-10-01 1975-06-11 Continental Pharma Amino-alcohols,their salts and process for preparing the same
US4327224A (en) * 1976-06-25 1982-04-27 Sterling Drug Inc. α-[(alkylamino)alkyl]-4-hydroxy-3-(alkylthio)benzenemethanols, derivatives thereof and intermediates therefor
GB1544872A (en) * 1976-06-25 1979-04-25 Sterling Drug Inc 4-hydroxyphenylalkanolamine derivatives and preparation thereof
US4898973A (en) * 1985-03-07 1990-02-06 Ici Americas Inc. Trisubstituted benzoic acid intermediates
JPH02134360A (ja) * 1988-09-21 1990-05-23 Hoechst Celanese Corp チオアルキル又はチオアリールフェノンの製法

Also Published As

Publication number Publication date
ATE123766T1 (de) 1995-06-15
EP0570488B1 (en) 1995-06-14
ZA92754B (en) 1992-12-30
BR9205584A (pt) 1994-05-03
DE69202970D1 (de) 1995-07-20
HU217447B (hu) 2000-01-28
DE69202970T2 (de) 1995-11-16
HU9302151D0 (en) 1993-11-29
HUT64947A (en) 1994-03-28
EP0570488A1 (en) 1993-11-24
US5101065A (en) 1992-03-31
DK0570488T3 (da) 1995-08-07
WO1992013834A1 (en) 1992-08-20

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