ES2040720T3 - Nuevos derivados de imidazolilguanidina, procedimiento para su fabricacion y medicamentos conteniendo estos compuestos. - Google Patents
Nuevos derivados de imidazolilguanidina, procedimiento para su fabricacion y medicamentos conteniendo estos compuestos.Info
- Publication number
- ES2040720T3 ES2040720T3 ES198787112906T ES87112906T ES2040720T3 ES 2040720 T3 ES2040720 T3 ES 2040720T3 ES 198787112906 T ES198787112906 T ES 198787112906T ES 87112906 T ES87112906 T ES 87112906T ES 2040720 T3 ES2040720 T3 ES 2040720T3
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- procedure
- manufacture
- new
- medicines containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
SE DESCRIBEN NUEVOS DERIVADOS DE IMIDAZOLIL GUANIDINA DE FORMULA GENERAL (I), QUE COMO CONSECUENCIA DE LA ACTIVIDAD AGONISTA SOBRE LOS RECEPTORES H2 DE HISTAMINA, ASI COMO TAMBIEN PARCIALMENTE COMO CONSECUENCIA DE SU ACTIVIDAD RECEPTORA ADICIONAL AGONISTA DE H1, PUEDEN APLICARSE EN ENFERMEDADES DEL CORAZON, EN DETERMINADAS FORMAS DE HIPERTONIA, ASI COMO EN ENFERMEDADES OBTURANTES DE LAS ARTERIAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19863631334 DE3631334A1 (de) | 1986-09-15 | 1986-09-15 | Neue imidazolylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2040720T3 true ES2040720T3 (es) | 1993-11-01 |
Family
ID=6309606
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198787112906T Expired - Lifetime ES2040720T3 (es) | 1986-09-15 | 1987-09-03 | Nuevos derivados de imidazolilguanidina, procedimiento para su fabricacion y medicamentos conteniendo estos compuestos. |
Country Status (17)
Country | Link |
---|---|
US (1) | US4912119A (es) |
EP (1) | EP0262448B1 (es) |
JP (1) | JPS6383072A (es) |
KR (1) | KR950010326B1 (es) |
AT (1) | ATE70533T1 (es) |
AU (1) | AU606882B2 (es) |
CA (1) | CA1249829A (es) |
DE (2) | DE3631334A1 (es) |
DK (1) | DK165982C (es) |
ES (1) | ES2040720T3 (es) |
GR (1) | GR3003388T3 (es) |
HU (1) | HU212302B (es) |
IE (1) | IE59278B1 (es) |
IL (1) | IL83804A (es) |
NZ (1) | NZ221611A (es) |
PT (1) | PT85697B (es) |
ZA (1) | ZA876163B (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0199845B1 (de) * | 1985-04-02 | 1990-08-01 | HEUMANN PHARMA GMBH & CO | Imidazolylalkylguanidinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
DE3726381A1 (de) * | 1987-08-07 | 1989-02-16 | Heumann Pharma Gmbh & Co | Guanidincarbonsaeureester, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3814057A1 (de) * | 1988-04-26 | 1989-11-09 | Heumann Pharma Gmbh & Co | 6-oxo-pyridazinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
ES2058651T3 (es) * | 1990-03-30 | 1994-11-01 | Heumann Pharma Gmbh & Co | Uso derivados de guanidina para la fabricacion de un medicamento con actividad antagonista de npy. |
NL9100365A (nl) * | 1991-02-27 | 1992-09-16 | Seed Capital Investments | Imidazoolderivaten met agonistische of antagonistische activiteit op de histamine h3-receptor. |
DE69222757T2 (de) * | 1991-02-27 | 1998-02-12 | Seed Capital Investments | Imidazol-derivate mit antagonistischer aktivität auf den histamin-h3-receptor |
EP0526395A1 (de) * | 1991-07-22 | 1993-02-03 | Zyma SA | Arylalkylaminderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
USRE37303E1 (en) * | 1992-01-10 | 2001-07-31 | Institut National Del La Sante Et De La Recherche Medicale | Imidazole compounds and their therapeutic applications |
FR2686084B1 (fr) * | 1992-01-10 | 1995-12-22 | Bioprojet Soc Civ | Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques. |
US6127343A (en) * | 1996-05-14 | 2000-10-03 | Novo Nordisk A/S | Somatostatin agonists and antagonists |
ZA974147B (en) * | 1996-05-14 | 1997-11-14 | Novo Nordisk As | Somatostatin agonists and antagonists. |
JP2001502712A (ja) * | 1996-10-31 | 2001-02-27 | ノボ ノルディスク アクティーゼルスカブ | 束縛されたソマトスタチン・アゴニスト及びアンタゴニスト |
US5889016A (en) * | 1997-06-26 | 1999-03-30 | Bristol-Myers Squibb Company | Dihydropyrimidone derivatives as NPY antagonists |
US6177429B1 (en) | 1999-06-21 | 2001-01-23 | Bristol-Myers Squibb Company | Dihydropyrazine derivatives as NPY antagonists |
MXPA03002447A (es) * | 2000-09-20 | 2003-07-21 | Schering Corp | Imidazoles sustituidos como agonistas o antagonistas duales h1 y h3 de histamina. |
KR101892241B1 (ko) * | 2015-11-06 | 2018-08-27 | 송재근 | 유분 분리 장치 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1431589A (en) * | 1973-07-13 | 1976-04-07 | Smith Kline French Lab | Ureas, thioureas and guanidines n,n-disubstituted by heterocyclo- alkylene and/or heterocycloalkylenethioalkylene groups |
IL49528A (en) * | 1975-05-21 | 1980-11-30 | Smith Kline French Lab | Imidazolyl(or thiazolyl)methylthio(or butyl)guanidine or thiourea derivatives,their preparation and pharmaceutical compositions comprising them |
DE2835695A1 (de) * | 1977-08-29 | 1979-03-15 | Yamanouchi Pharma Co Ltd | Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten |
DK221081A (da) * | 1980-05-31 | 1981-12-01 | Smith Kline French Lab | Fremgangsmaade til fremstilling af heterocyklylalkylanidiner mellemprodukter til anvendelse ved denne fremgangsmaade og en fremgangsmaade til fremstilling af disse mellemprodukter |
JPH0660096B2 (ja) * | 1983-11-04 | 1994-08-10 | 富山化学工業株式会社 | アミン誘導体またはその塩を含有する抗潰瘍剤 |
DE3528214A1 (de) * | 1985-08-06 | 1987-02-12 | Heumann Ludwig & Co Gmbh | Arylalkylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
EP0199845B1 (de) * | 1985-04-02 | 1990-08-01 | HEUMANN PHARMA GMBH & CO | Imidazolylalkylguanidinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
DE3726381A1 (de) * | 1987-08-07 | 1989-02-16 | Heumann Pharma Gmbh & Co | Guanidincarbonsaeureester, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1986
- 1986-09-15 DE DE19863631334 patent/DE3631334A1/de not_active Withdrawn
-
1987
- 1987-08-20 ZA ZA876163A patent/ZA876163B/xx unknown
- 1987-08-21 CA CA000545051A patent/CA1249829A/en not_active Expired
- 1987-08-28 AU AU77672/87A patent/AU606882B2/en not_active Ceased
- 1987-08-28 NZ NZ221611A patent/NZ221611A/xx unknown
- 1987-09-03 DE DE8787112906T patent/DE3775319D1/de not_active Expired - Fee Related
- 1987-09-03 ES ES198787112906T patent/ES2040720T3/es not_active Expired - Lifetime
- 1987-09-03 EP EP87112906A patent/EP0262448B1/de not_active Expired - Lifetime
- 1987-09-03 AT AT87112906T patent/ATE70533T1/de not_active IP Right Cessation
- 1987-09-06 IL IL83804A patent/IL83804A/xx not_active IP Right Cessation
- 1987-09-10 DK DK472887A patent/DK165982C/da active
- 1987-09-11 KR KR1019870010072A patent/KR950010326B1/ko active IP Right Grant
- 1987-09-14 US US07/095,892 patent/US4912119A/en not_active Expired - Fee Related
- 1987-09-14 HU HU874069A patent/HU212302B/hu not_active IP Right Cessation
- 1987-09-14 JP JP62230875A patent/JPS6383072A/ja active Pending
- 1987-09-14 IE IE246387A patent/IE59278B1/en not_active IP Right Cessation
- 1987-09-14 PT PT85697A patent/PT85697B/pt not_active IP Right Cessation
-
1991
- 1991-12-19 GR GR91400990T patent/GR3003388T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE70533T1 (de) | 1992-01-15 |
DK472887D0 (da) | 1987-09-10 |
DE3775319D1 (de) | 1992-01-30 |
HUT56352A (en) | 1991-08-28 |
DE3631334A1 (de) | 1988-03-17 |
PT85697B (pt) | 1990-08-31 |
GR3003388T3 (en) | 1993-02-17 |
AU606882B2 (en) | 1991-02-21 |
IE59278B1 (en) | 1994-02-09 |
CA1249829A (en) | 1989-02-07 |
IE872463L (en) | 1988-03-15 |
KR880003937A (ko) | 1988-06-01 |
IL83804A0 (en) | 1988-02-29 |
EP0262448B1 (de) | 1991-12-18 |
KR950010326B1 (ko) | 1995-09-14 |
AU7767287A (en) | 1988-03-17 |
JPS6383072A (ja) | 1988-04-13 |
DK472887A (da) | 1988-03-16 |
EP0262448A1 (de) | 1988-04-06 |
ZA876163B (en) | 1988-02-23 |
IL83804A (en) | 1993-02-21 |
DK165982B (da) | 1993-02-22 |
DK165982C (da) | 1993-07-26 |
PT85697A (de) | 1987-10-01 |
HU212302B (en) | 1996-05-28 |
US4912119A (en) | 1990-03-27 |
NZ221611A (en) | 1989-09-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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